CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = Y145Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	145	Y145Y		syn	taC	taT	3147	3147	1	21995-21997

Details of the mutation Y145Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	145	Y145Y	taC	taT	3147	3147	All	0.000602
S	145	Y145Y	taC	taT	557	557	AY.4	0.000867
S	145	Y145Y	taC	taT	209	209	AY.44	0.001272
S	145	Y145Y	taC	taT	171	171	B.1.617.2	0.000644
S	145	Y145Y	taC	taT	167	167	P.1	0.002631
S	145	Y145Y	taC	taT	125	125	AY.39	0.003089
S	145	Y145Y	taC	taT	120	120	AY.43	0.000532
S	145	Y145Y	taC	taT	112	112	B.1.2	0.000986
S	145	Y145Y	taC	taT	83	83	AY.25	0.000499
S	145	Y145Y	taC	taT	82	82	AY.3	0.000816
S	145	Y145Y	taC	taT	81	81	AY.99.2	0.007465
S	145	Y145Y	taC	taT	79	79	B.1.568	0.087778
S	145	Y145Y	taC	taT	77	77	B.1.177	0.001014
S	145	Y145Y	taC	taT	70	70	B.1.177.21	0.005353
S	145	Y145Y	taC	taT	68	68	AY.103	0.000422
S	145	Y145Y	taC	taT	60	60	B.1	0.00055
S	145	Y145Y	taC	taT	42	42	B.1.526	0.000987
S	145	Y145Y	taC	taT	41	41	AY.120	0.001524
S	145	Y145Y	taC	taT	37	37	AY.100	0.001702
S	145	Y145Y	taC	taT	37	37	AY.5	0.000764
S	145	Y145Y	taC	taT	37	37	B.1.497	0.011646
S	145	Y145Y	taC	taT	35	35	AY.102	0.000928
S	145	Y145Y	taC	taT	34	34	AY.26	0.000963
S	145	Y145Y	taC	taT	33	33	B.1.160.30	0.098214
S	145	Y145Y	taC	taT	31	31	B.1.561	0.012306
S	145	Y145Y	taC	taT	30	30	B.1.1	0.000544
S	145	Y145Y	taC	taT	26	26	B.1.1.44	0.062651
S	145	Y145Y	taC	taT	25	25	B.1.160	0.00078
S	145	Y145Y	taC	taT	23	23	B.1.243	0.0016
S	145	Y145Y	taC	taT	22	22	AY.42	0.000885
S	145	Y145Y	taC	taT	22	22	B.1.466.2	0.008607
S	145	Y145Y	taC	taT	19	19	B.1.429	0.000447
S	145	Y145Y	taC	taT	17	17	AY.27	0.0011
S	145	Y145Y	taC	taT	15	15	AY.29	0.000237
S	145	Y145Y	taC	taT	15	15	AY.47	0.000467
S	145	Y145Y	taC	taT	15	15	B.1.621	0.001328
S	145	Y145Y	taC	taT	14	14	AY.75	0.000784
S	145	Y145Y	taC	taT	14	14	B.1.232	0.007523
S	145	Y145Y	taC	taT	12	12	B.1.214.2	0.007194
S	145	Y145Y	taC	taT	12	12	B.1.381	0.09375
S	145	Y145Y	taC	taT	11	11	AY.113	0.001566
S	145	Y145Y	taC	taT	11	11	AY.59	0.005826
S	145	Y145Y	taC	taT	11	11	B.1.177.64	1
S	145	Y145Y	taC	taT	11	11	B.1.596	0.000959
S	145	Y145Y	taC	taT	10	10	AY.46.5	0.001984
S	145	Y145Y	taC	taT	10	10	B.1.1.28	0.003112
S	145	Y145Y	taC	taT	9	9	AY.20	0.00035
S	145	Y145Y	taC	taT	9	9	B.1.1.214	0.000499
S	145	Y145Y	taC	taT	9	9	B.1.234	0.001187
S	145	Y145Y	taC	taT	9	9	B.1.369	0.002567
S	145	Y145Y	taC	taT	9	9	P.1.15	0.002091
S	145	Y145Y	taC	taT	8	8	B.1.1.519	0.000318
S	145	Y145Y	taC	taT	8	8	B.1.160.10	0.064516
S	145	Y145Y	taC	taT	8	8	B.1.617.1	0.001032
S	145	Y145Y	taC	taT	7	7	A.23.1	0.00493
S	145	Y145Y	taC	taT	7	7	B.1.351.2	0.002118
S	145	Y145Y	taC	taT	7	7	D.2	0.000525
S	145	Y145Y	taC	taT	6	6	AY.39.1	0.000238
S	145	Y145Y	taC	taT	6	6	B.1.1.294	0.007595
S	145	Y145Y	taC	taT	6	6	B.1.110.3	0.00431
S	145	Y145Y	taC	taT	6	6	B.1.351	0.000178
S	145	Y145Y	taC	taT	6	6	P.1.14	0.000287
S	145	Y145Y	taC	taT	5	5	A.2.5.3	0.051546
S	145	Y145Y	taC	taT	5	5	AY.106	0.001674
S	145	Y145Y	taC	taT	5	5	AY.28	0.009452
S	145	Y145Y	taC	taT	5	5	AY.61	0.000524
S	145	Y145Y	taC	taT	5	5	AY.85	0.002136
S	145	Y145Y	taC	taT	5	5	AY.98	0.000395
S	145	Y145Y	taC	taT	5	5	B.1.177.86	0.000917
S	145	Y145Y	taC	taT	5	5	B.1.409	0.003906
S	145	Y145Y	taC	taT	5	5	C.36.3	0.002836
S	145	Y145Y	taC	taT	4	4	AD.2	0.000876
S	145	Y145Y	taC	taT	4	4	AY.119	0.000141
S	145	Y145Y	taC	taT	4	4	AY.33	0.000267
S	145	Y145Y	taC	taT	4	4	AY.39.2	0.006163
S	145	Y145Y	taC	taT	4	4	AY.46.4	0.000658
S	145	Y145Y	taC	taT	4	4	AY.75.1	0.000721
S	145	Y145Y	taC	taT	4	4	AY.88	0.003537
S	145	Y145Y	taC	taT	4	4	AY.9.2	0.000147
S	145	Y145Y	taC	taT	4	4	AY.98.1	0.000194
S	145	Y145Y	taC	taT	4	4	B.1.177.12	0.000607
S	145	Y145Y	taC	taT	4	4	B.1.408	0.01476
S	145	Y145Y	taC	taT	4	4	C.37	0.000464
S	145	Y145Y	taC	taT	4	4	P.1.1	0.001271
S	145	Y145Y	taC	taT	3	3	A.2	0.001985
S	145	Y145Y	taC	taT	3	3	A.2.5	0.001497
S	145	Y145Y	taC	taT	3	3	AY.1	0.001187
S	145	Y145Y	taC	taT	3	3	AY.110	0.000338
S	145	Y145Y	taC	taT	3	3	AY.111	0.000549
S	145	Y145Y	taC	taT	3	3	AY.13	0.000483
S	145	Y145Y	taC	taT	3	3	AY.23	0.000209
S	145	Y145Y	taC	taT	3	3	AY.7.1	0.000338
S	145	Y145Y	taC	taT	3	3	AY.9.1	0.000251
S	145	Y145Y	taC	taT	3	3	B.1.1.432	0.003797
S	145	Y145Y	taC	taT	3	3	B.1.240	0.000647
S	145	Y145Y	taC	taT	3	3	B.1.241	0.002435
S	145	Y145Y	taC	taT	3	3	B.1.36	0.000438
S	145	Y145Y	taC	taT	3	3	B.1.628	0.001057
S	145	Y145Y	taC	taT	3	3	B.6.6	0.002667
S	145	Y145Y	taC	taT	3	3	P.1.12	0.001452
S	145	Y145Y	taC	taT	3	3	P.1.17	0.000485
S	145	Y145Y	taC	taT	3	3	P.2	0.00056
S	145	Y145Y	taC	taT	3	3	R.1	0.00027
S	145	Y145Y	taC	taT	2	2	A.1	0.000564
S	145	Y145Y	taC	taT	2	2	AY.23.1	0.000835
S	145	Y145Y	taC	taT	2	2	AY.29.1	0.000441
S	145	Y145Y	taC	taT	2	2	AY.45	0.000243
S	145	Y145Y	taC	taT	2	2	AY.46.6	0.000144
S	145	Y145Y	taC	taT	2	2	AY.53	0.000575
S	145	Y145Y	taC	taT	2	2	AY.55	0.001835
S	145	Y145Y	taC	taT	2	2	AY.6	0.000082
S	145	Y145Y	taC	taT	2	2	AY.69	0.000373
S	145	Y145Y	taC	taT	2	2	AY.9	0.000135
S	145	Y145Y	taC	taT	2	2	B.1.1.221	0.020202
S	145	Y145Y	taC	taT	2	2	B.1.1.306	0.000877
S	145	Y145Y	taC	taT	2	2	B.1.1.317	0.000823
S	145	Y145Y	taC	taT	2	2	B.1.1.326	0.003521
S	145	Y145Y	taC	taT	2	2	B.1.1.351	0.005587
S	145	Y145Y	taC	taT	2	2	B.1.1.7	0.000002
S	145	Y145Y	taC	taT	2	2	B.1.13	0.004751
S	145	Y145Y	taC	taT	2	2	B.1.177.7	0.00033
S	145	Y145Y	taC	taT	2	2	B.1.279	0.001027
S	145	Y145Y	taC	taT	2	2	B.1.36.18	0.00084
S	145	Y145Y	taC	taT	2	2	B.1.36.29	0.001035
S	145	Y145Y	taC	taT	2	2	B.1.564	0.000852
S	145	Y145Y	taC	taT	2	2	B.1.582	0.000981
S	145	Y145Y	taC	taT	2	2	B.1.595	0.000522
S	145	Y145Y	taC	taT	2	2	B.1.612	0.005305
S	145	Y145Y	taC	taT	2	2	B.1.9.4	0.01227
S	145	Y145Y	taC	taT	1	1		0.055556
S	145	Y145Y	taC	taT	1	1	AC.1	0.037037
S	145	Y145Y	taC	taT	1	1	AY.114	0.000231
S	145	Y145Y	taC	taT	1	1	AY.116	0.000287
S	145	Y145Y	taC	taT	1	1	AY.12	0.000316
S	145	Y145Y	taC	taT	1	1	AY.121	0.000135
S	145	Y145Y	taC	taT	1	1	AY.14	0.000088
S	145	Y145Y	taC	taT	1	1	AY.16	0.00038
S	145	Y145Y	taC	taT	1	1	AY.22	0.002092
S	145	Y145Y	taC	taT	1	1	AY.24	0.000431
S	145	Y145Y	taC	taT	1	1	AY.3.1	0.000085
S	145	Y145Y	taC	taT	1	1	AY.30	0.000396
S	145	Y145Y	taC	taT	1	1	AY.34	0.000097
S	145	Y145Y	taC	taT	1	1	AY.36	0.000148
S	145	Y145Y	taC	taT	1	1	AY.38	0.000499
S	145	Y145Y	taC	taT	1	1	AY.46	0.000104
S	145	Y145Y	taC	taT	1	1	AY.46.2	0.000635
S	145	Y145Y	taC	taT	1	1	AY.51	0.000909
S	145	Y145Y	taC	taT	1	1	AY.52	0.000814
S	145	Y145Y	taC	taT	1	1	AY.54	0.000095
S	145	Y145Y	taC	taT	1	1	AY.56	0.001605
S	145	Y145Y	taC	taT	1	1	AY.57	0.000656
S	145	Y145Y	taC	taT	1	1	AY.62	0.000436
S	145	Y145Y	taC	taT	1	1	AY.64	0.000595
S	145	Y145Y	taC	taT	1	1	AY.65	0.000533
S	145	Y145Y	taC	taT	1	1	AY.72	0.001361
S	145	Y145Y	taC	taT	1	1	AY.74	0.000116
S	145	Y145Y	taC	taT	1	1	AY.78	0.001541
S	145	Y145Y	taC	taT	1	1	AY.92	0.000287
S	145	Y145Y	taC	taT	1	1	AY.99	0.001049
S	145	Y145Y	taC	taT	1	1	B.1.1.1	0.000327
S	145	Y145Y	taC	taT	1	1	B.1.1.141	0.002012
S	145	Y145Y	taC	taT	1	1	B.1.1.157	0.000913
S	145	Y145Y	taC	taT	1	1	B.1.1.189	0.001513
S	145	Y145Y	taC	taT	1	1	B.1.1.216	0.00089
S	145	Y145Y	taC	taT	1	1	B.1.1.222	0.000204
S	145	Y145Y	taC	taT	1	1	B.1.1.303	0.002762
S	145	Y145Y	taC	taT	1	1	B.1.1.311	0.000358
S	145	Y145Y	taC	taT	1	1	B.1.1.348	0.000796
S	145	Y145Y	taC	taT	1	1	B.1.1.354	0.004386
S	145	Y145Y	taC	taT	1	1	B.1.1.419	0.007407
S	145	Y145Y	taC	taT	1	1	B.1.1.47	0.005348
S	145	Y145Y	taC	taT	1	1	B.1.1.486	0.001577
S	145	Y145Y	taC	taT	1	1	B.1.1.50	0.000679
S	145	Y145Y	taC	taT	1	1	B.1.1.517	0.006803
S	145	Y145Y	taC	taT	1	1	B.1.1.528	0.004808
S	145	Y145Y	taC	taT	1	1	B.1.1.63	0.000386
S	145	Y145Y	taC	taT	1	1	B.1.110	0.004525
S	145	Y145Y	taC	taT	1	1	B.1.126	0.001276
S	145	Y145Y	taC	taT	1	1	B.1.160.7	0.002079
S	145	Y145Y	taC	taT	1	1	B.1.177.3	0.007634
S	145	Y145Y	taC	taT	1	1	B.1.177.4	0.000211
S	145	Y145Y	taC	taT	1	1	B.1.177.43	0.001477
S	145	Y145Y	taC	taT	1	1	B.1.177.53	0.002392
S	145	Y145Y	taC	taT	1	1	B.1.177.56	0.000668
S	145	Y145Y	taC	taT	1	1	B.1.177.74	0.015152
S	145	Y145Y	taC	taT	1	1	B.1.177.75	0.001041
S	145	Y145Y	taC	taT	1	1	B.1.177.81	0.000189
S	145	Y145Y	taC	taT	1	1	B.1.189	0.004292
S	145	Y145Y	taC	taT	1	1	B.1.208	0.04
S	145	Y145Y	taC	taT	1	1	B.1.210	0.002132
S	145	Y145Y	taC	taT	1	1	B.1.214	0.003663
S	145	Y145Y	taC	taT	1	1	B.1.221	0.000071
S	145	Y145Y	taC	taT	1	1	B.1.239	0.001221
S	145	Y145Y	taC	taT	1	1	B.1.240.2	0.030303
S	145	Y145Y	taC	taT	1	1	B.1.258.17	0.000104
S	145	Y145Y	taC	taT	1	1	B.1.3	0.002618
S	145	Y145Y	taC	taT	1	1	B.1.311	0.000275
S	145	Y145Y	taC	taT	1	1	B.1.343	0.020833
S	145	Y145Y	taC	taT	1	1	B.1.36.17	0.000494
S	145	Y145Y	taC	taT	1	1	B.1.360	0.012658
S	145	Y145Y	taC	taT	1	1	B.1.396	0.000706
S	145	Y145Y	taC	taT	1	1	B.1.399	0.001934
S	145	Y145Y	taC	taT	1	1	B.1.433	0.003195
S	145	Y145Y	taC	taT	1	1	B.1.459	0.004082
S	145	Y145Y	taC	taT	1	1	B.1.470	0.001404
S	145	Y145Y	taC	taT	1	1	B.1.503	0.002488
S	145	Y145Y	taC	taT	1	1	B.1.523	0.002451
S	145	Y145Y	taC	taT	1	1	B.1.524	0.001406
S	145	Y145Y	taC	taT	1	1	B.1.527	0.003704
S	145	Y145Y	taC	taT	1	1	B.1.575	0.000303
S	145	Y145Y	taC	taT	1	1	B.1.588	0.00091
S	145	Y145Y	taC	taT	1	1	B.1.597	0.00463
S	145	Y145Y	taC	taT	1	1	B.1.623	0.000536
S	145	Y145Y	taC	taT	1	1	B.11	0.005128
S	145	Y145Y	taC	taT	1	1	B.40	0.000364
S	145	Y145Y	taC	taT	1	1	P.1.16	0.000374
S	145	Y145Y	taC	taT	1	1	P.1.2	0.001156

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.