CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = W258L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S258W258LnonsyntGgtTg13596135880.99941222334-22336
S258W258LnonsynTGgCTg1359640.00029420422334-22336
S258W258LnonsyntGGtTA1359620.00014710222334-22336
S258W258LnonsynTGGCTT1359610.00007355122334-22336
S258W258LnonsynTGGCTC1359610.00007355122334-22336

Details of the mutation W258L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S258W258LtGgtTg1358813596All0.002599
S258W258LTGgCTg413596All0.000001
S258W258LtGGtTA213596All0
S258W258LTGGCTC113596All0
S258W258LTGGCTT113596All0
S258W258LtGgtTg51375137B.1.4270.259405
S258W258LtGgtTg22802280AY.10.902256
S258W258LtGgtTg750752B.1.1.70.000671
S258W258LtGGtTA1752B.1.1.70.000001
S258W258LTGGCTT1752B.1.1.70.000001
S258W258LtGgtTg658661AY.430.002915
S258W258LTGgCTg2661AY.430.000009
S258W258LTGGCTC1661AY.430.000004
S258W258LtGgtTg621621AY.40.000967
S258W258LtGgtTg434435B.1.617.20.001634
S258W258LTGgCTg1435B.1.617.20.000004
S258W258LtGgtTg301301AY.330.0201
S258W258LtGgtTg221221AY.250.001329
S258W258LtGgtTg206206AY.30.002049
S258W258LtGgtTg178179B.10.00163
S258W258LTGgCTg1179B.10.000009
S258W258LtGgtTg177177AZ.50.621053
S258W258LtGgtTg135135AY.440.000822
S258W258LtGgtTg114114AY.1030.000708
S258W258LtGgtTg111111B.1.6370.008111
S258W258LtGgtTg9696AY.50.001982
S258W258LtGgtTg8383AY.690.015494
S258W258LtGgtTg7979AY.390.001952
S258W258LtGgtTg7979B.1.4290.001859
S258W258LtGgtTg6464AY.1210.00866
S258W258LtGgtTg5959AY.99.20.005437
S258W258LtGgtTg5656P.1.140.002677
S258W258LtGgtTg5555AY.1060.018419
S258W258LtGgtTg5555B.1.5260.001293
S258W258LtGgtTg5252AY.1170.004395
S258W258LtGgtTg4848AY.200.001866
S258W258LtGgtTg4848AY.60.001974
S258W258LtGgtTg4747AY.750.002633
S258W258LtGgtTg4646AY.1020.00122
S258W258LtGgtTg4444AY.260.001246
S258W258LtGgtTg4444AY.39.10.001743
S258W258LtGgtTg4343AY.1200.001599
S258W258LtGgtTg4040AY.920.011491
S258W258LtGgtTg3838AY.90.002569
S258W258LtGgtTg3434AY.4.20.000737
S258W258LtGgtTg3232AY.590.016949
S258W258LtGgtTg3131AY.970.052721
S258W258LtGgtTg3030AY.7.10.003381
S258W258LtGgtTg3030Q.20.018405
S258W258LtGgtTg2929AY.290.000457
S258W258LtGgtTg2929AY.9.20.001065
S258W258LtGgtTg2929B.1.10.000526
S258W258LtGgtTg2828B.1.617.10.003611
S258W258LtGgtTg2727B.1.1.2530.067669
S258W258LtGgtTg2626AY.98.10.001259
S258W258LtGgtTg2525B.1.1.4800.625
S258W258LtGgtTg2424B.1.20.000211
S258W258LtGgtTg2323B.1.3690.00656
S258W258LtGgtTg2222AY.910.01607
S258W258LtGgtTg2020B.1.1770.000263
S258W258LtGgtTg1919B.1.1570.056716
S258W258LtGgtTg1818AY.230.001255
S258W258LtGgtTg1616AY.1190.000565
S258W258LtGgtTg1616AY.540.001526
S258W258LtGgtTg1616AY.730.010645
S258W258LtGgtTg1616B.1.1.5190.000635
S258W258LtGgtTg1515AY.1130.002136
S258W258LtGgtTg1515AY.420.000603
S258W258LtGgtTg1414P.10.000221
S258W258LtGgtTg1313B.1.1600.000405
S258W258LtGgtTg1212AY.850.005126
S258W258LtGgtTg1212B.1.3890.012024
S258W258LtGgtTg1212P.20.00224
S258W258LtGgtTg1111AY.1000.000506
S258W258LtGgtTg1111AY.460.001145
S258W258LtGgtTg1111AY.960.022822
S258W258LtGgtTg1111AY.980.000869
S258W258LtGgtTg1010A.2.50.00499
S258W258LtGgtTg1010AY.1180.000626
S258W258LtGgtTg1010AY.450.001217
S258W258LtGgtTg1010AY.820.013569
S258W258LtGgtTg1010B.1.3360.02439
S258W258LtGgtTg1010B.1.3510.000297
S258W258LtGgtTg1010B.1.575.10.02439
S258W258LtGgtTg99AY.340.000873
S258W258LtGgtTg99B.1.6190.00784
S258W258LtGgtTg99D.20.000675
S258W258LtGgtTg88AY.46.60.000578
S258W258LtGgtTg88AY.740.000925
S258W258LtGgtTg88AY.9.10.00067
S258W258LtGgtTg88B.1.5950.002088
S258W258LtGgtTg77AY.630.002708
S258W258LtGgtTg77B.1.1.1360.148936
S258W258LtGgtTg66AY.46.40.000987
S258W258LtGgtTg66B.1.1.3990.545455
S258W258LtGgtTg55AY.130.000805
S258W258LtGgtTg55AY.240.002155
S258W258LtGgtTg55AY.3.10.000426
S258W258LtGgtTg55AY.4.50.000537
S258W258LtGgtTg55AY.600.00469
S258W258LtGgtTg55AY.610.000524
S258W258LtGgtTg55AY.670.002321
S258W258LtGgtTg55AY.75.10.000902
S258W258LtGgtTg55B.1.1.250.002843
S258W258LtGgtTg55B.1.1.3180.001509
S258W258LtGgtTg55B.1.1.330.002104
S258W258LtGgtTg55B.1.2580.000333
S258W258LtGgtTg55B.1.258.170.00052
S258W258LtGgtTg55B.1.360.00073
S258W258LtGgtTg55B.1.466.20.001956
S258W258LtGgtTg55B.1.5960.000436
S258W258LtGgtTg55B.1.6210.000443
S258W258LtGgtTg44AY.1160.001147
S258W258LtGgtTg44AY.270.000259
S258W258LtGgtTg44AY.4.40.001637
S258W258LtGgtTg44AY.510.003636
S258W258LtGgtTg44AY.550.00367
S258W258LtGgtTg44AY.560.006421
S258W258LtGgtTg44AY.620.001743
S258W258LtGgtTg44AY.700.000834
S258W258LtGgtTg44AY.800.004515
S258W258LtGgtTg44AY.930.001092
S258W258LtGgtTg44B.1.1.280.001245
S258W258LtGgtTg44B.1.177.450.001525
S258W258LtGgtTg44B.1.2430.000278
S258W258LtGgtTg44C.370.000464
S258W258LtGgtTg44P.1.10.001271
S258W258LtGgtTg33A.300.428571
S258W258LtGgtTg33AY.1100.000338
S258W258LtGgtTg33AY.1110.000549
S258W258LtGgtTg33AY.29.10.000662
S258W258LtGgtTg33AY.470.000093
S258W258LtGgtTg33AY.5.30.001012
S258W258LtGgtTg33AY.680.000821
S258W258LtGgtTg33B.1.1.1890.004539
S258W258LtGgtTg33B.1.1.2160.002671
S258W258LtGgtTg33B.1.1.2910.002227
S258W258LtGgtTg33B.1.2400.000647
S258W258LtGgtTg33C.180.007772
S258W258LtGgtTg33P.1.40.00293
S258W258LtGgtTg22A.240.142857
S258W258LtGgtTg22AY.1050.001286
S258W258LtGgtTg22AY.1090.001479
S258W258LtGgtTg22AY.120.000632
S258W258LtGgtTg22AY.16.10.00094
S258W258LtGgtTg22AY.280.003781
S258W258LtGgtTg22AY.300.000791
S258W258LtGgtTg22AY.34.10.00102
S258W258LtGgtTg22AY.360.000296
S258W258LtGgtTg22AY.400.001929
S258W258LtGgtTg22AY.46.20.001271
S258W258LtGgtTg22AY.46.30.001867
S258W258LtGgtTg22AY.480.00093
S258W258LtGgtTg22AY.520.001629
S258W258LtGgtTg22AY.650.001066
S258W258LtGgtTg22AY.780.003082
S258W258LtGgtTg22AY.790.002421
S258W258LtGgtTg22AY.80.001212
S258W258LtGgtTg22AY.840.000875
S258W258LtGgtTg22AY.870.001665
S258W258LtGgtTg22B0.000256
S258W258LtGgtTg22B.1.1.2140.000111
S258W258LtGgtTg22B.1.1.2220.000408
S258W258LtGgtTg22B.1.1.2770.001517
S258W258LtGgtTg22B.1.1.3290.007692
S258W258LtGgtTg22B.1.1.3350.025974
S258W258LtGgtTg22B.1.1.3480.001592
S258W258LtGgtTg22B.1.1.4640.002946
S258W258LtGgtTg22B.1.1.630.000772
S258W258LtGgtTg22B.1.120.016
S258W258LtGgtTg22B.1.177.210.000153
S258W258LtGgtTg22B.1.177.430.002954
S258W258LtGgtTg22B.1.177.570.000562
S258W258LtGgtTg22B.1.177.70.00033
S258W258LtGgtTg22B.1.177.730.001133
S258W258LtGgtTg22B.1.2210.000142
S258W258LtGgtTg22B.1.3670.001585
S258W258LtGgtTg22B.1.438.10.000215
S258W258LtGgtTg22B.1.4970.00063
S258W258LtGgtTg22B.1.5900.009091
S258W258LtGgtTg22B.1.617.30.00597
S258W258LtGgtTg22B.1.6280.000705
S258W258LtGgtTg22B.400.000729
S258W258LtGgtTg22P.1.150.000465
S258W258LtGgtTg22Q.80.00033
S258W258LtGgtTg11A0.000387
S258W258LtGgtTg11A.2.20.001689
S258W258LtGgtTg11A.23.10.000704
S258W258LtGgtTg11AY.1010.00049
S258W258LtGgtTg11AY.1080.001103
S258W258LtGgtTg11AY.140.000088
S258W258LtGgtTg11AY.160.00038
S258W258LtGgtTg11AY.190.00114
S258W258LtGgtTg11AY.220.002092
S258W258LtGgtTg11AY.320.000532
S258W258LtGgtTg11AY.380.000499
S258W258LtGgtTg11AY.4.2.10.000149
S258W258LtGgtTg11AY.490.003195
S258W258LtGgtTg11AY.5.40.000277
S258W258LtGgtTg11AY.580.000907
S258W258LtGgtTg11AY.770.001127
S258W258LtGgtTg11AY.860.00083
S258W258LtGgtTg11AY.880.000884
S258W258LtGgtTg11AY.940.000443
S258W258LtGgtTg11AY.950.000761
S258W258LtGgtTg11AY.990.001049
S258W258LtGgtTg11AZ.20.000821
S258W258LtGgtTg11B.1.1.10.000327
S258W258LtGgtTg11B.1.1.1530.001095
S258W258LtGgtTg11B.1.1.1860.003436
S258W258LtGgtTg11B.1.1.1980.001468
S258W258LtGgtTg11B.1.1.2200.001859
S258W258LtGgtTg11B.1.1.2690.001353
S258W258LtGgtTg11B.1.1.2840.000107
S258W258LtGgtTg11B.1.1.3170.000412
S258W258LtGgtTg11B.1.1.3440.010753
S258W258LtGgtTg11B.1.1.3590.027778
S258W258LtGgtTg11B.1.1.3690.000446
S258W258LtGgtTg11B.1.1.3880.045455
S258W258LtGgtTg11B.1.1.390.00051
S258W258LtGgtTg11B.1.1.4160.000905
S258W258LtGgtTg11B.1.1.4320.001266
S258W258LtGgtTg11B.1.1.460.004367
S258W258LtGgtTg11B.1.1130.015625
S258W258LtGgtTg11B.1.177.320.00135
S258W258LtGgtTg11B.1.177.350.000691
S258W258LtGgtTg11B.1.177.50.001242
S258W258LtGgtTg11B.1.177.60.000977
S258W258LtGgtTg11B.1.177.600.000218
S258W258LtGgtTg11B.1.177.650.000665
S258W258LtGgtTg11B.1.177.80.000752
S258W258LtGgtTg11B.1.177.830.001481
S258W258LtGgtTg11B.1.177.860.000183
S258W258LtGgtTg11B.1.177.870.000728
S258W258LtGgtTg11B.1.177.90.001332
S258W258LtGgtTg11B.1.2060.000816
S258W258LtGgtTg11B.1.2270.047619
S258W258LtGgtTg11B.1.2320.000537
S258W258LtGgtTg11B.1.258.120.007874
S258W258LtGgtTg11B.1.2790.000514
S258W258LtGgtTg11B.1.2890.00266
S258W258LtGgtTg11B.1.3110.000275
S258W258LtGgtTg11B.1.36.220.001208
S258W258LtGgtTg11B.1.36.380.001642
S258W258LtGgtTg11B.1.36.80.001
S258W258LtGgtTg11B.1.3610.001289
S258W258LtGgtTg11B.1.3950.007042
S258W258LtGgtTg11B.1.3980.002976
S258W258LtGgtTg11B.1.4000.000429
S258W258LtGgtTg11B.1.416.10.001563
S258W258LtGgtTg11B.1.4990.00105
S258W258LtGgtTg11B.1.5380.008065
S258W258LtGgtTg11B.1.5610.000397
S258W258LtGgtTg11B.1.5650.00081
S258W258LtGgtTg11B.1.5750.000303
S258W258LtGGtTA11B.1.5770.000687
S258W258LtGgtTg11B.1.5780.017857
S258W258LtGgtTg11B.1.5870.001898
S258W258LtGgtTg11B.1.6200.000946
S258W258LtGgtTg11B.1.940.027027
S258W258LtGgtTg11B.60.00091
S258W258LtGgtTg11C.36.30.000567
S258W258LtGgtTg11P.1.120.000484
S258W258LtGgtTg11P.1.160.000374
S258W258LtGgtTg11P.1.170.000162
S258W258LtGgtTg11P.1.20.001156
S258W258LtGgtTg11P.1.80.004785
S258W258LtGgtTg11Q.10.000126
S258W258LtGgtTg11Q.70.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.