CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 791 | T791I | nonsyn | aCa | aTa | 8138 | 8137 | 0.999877 | 23933-23935 | |
S | 791 | T791I | nonsyn | aCA | aTC | 8138 | 1 | 0.00012288 | 23933-23935 |
Details of the mutation T791I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 791 | T791I | aCa | aTa | 8137 | 8138 | All | 0.001556 |
S | 791 | T791I | aCA | aTC | 1 | 8138 | All | 0 |
S | 791 | T791I | aCa | aTa | 2985 | 2985 | AY.12 | 0.943426 |
S | 791 | T791I | aCa | aTa | 1870 | 1870 | B.1.637 | 0.136646 |
S | 791 | T791I | aCa | aTa | 1059 | 1059 | B.1.1.7 | 0.000948 |
S | 791 | T791I | aCa | aTa | 758 | 758 | AY.43 | 0.003358 |
S | 791 | T791I | aCa | aTa | 252 | 252 | AY.4 | 0.000392 |
S | 791 | T791I | aCa | aTa | 122 | 122 | AY.9.2 | 0.004481 |
S | 791 | T791I | aCa | aTa | 93 | 93 | AY.44 | 0.000566 |
S | 791 | T791I | aCa | aTa | 83 | 83 | P.1 | 0.001308 |
S | 791 | T791I | aCa | aTa | 51 | 51 | AY.103 | 0.000317 |
S | 791 | T791I | aCa | aTa | 48 | 48 | B.1 | 0.00044 |
S | 791 | T791I | aCa | aTa | 44 | 44 | B.1.617.2 | 0.000166 |
S | 791 | T791I | aCa | aTa | 42 | 42 | AY.29 | 0.000662 |
S | 791 | T791I | aCa | aTa | 38 | 38 | B.1.351 | 0.00113 |
S | 791 | T791I | aCa | aTa | 32 | 32 | AY.84 | 0.013998 |
S | 791 | T791I | aCa | aTa | 32 | 32 | B.1.177.21 | 0.002447 |
S | 791 | T791I | aCa | aTa | 25 | 25 | AY.25 | 0.00015 |
S | 791 | T791I | aCa | aTa | 23 | 24 | AY.3 | 0.000229 |
S | 791 | T791I | aCA | aTC | 1 | 24 | AY.3 | 0.00001 |
S | 791 | T791I | aCa | aTa | 23 | 23 | B.1.595 | 0.006002 |
S | 791 | T791I | aCa | aTa | 22 | 22 | B.1.438.1 | 0.00236 |
S | 791 | T791I | aCa | aTa | 18 | 18 | B.1.177 | 0.000237 |
S | 791 | T791I | aCa | aTa | 17 | 17 | AY.118 | 0.001065 |
S | 791 | T791I | aCa | aTa | 17 | 17 | AY.42 | 0.000684 |
S | 791 | T791I | aCa | aTa | 16 | 16 | B.1.177.60 | 0.003495 |
S | 791 | T791I | aCa | aTa | 15 | 15 | AY.46.6 | 0.001083 |
S | 791 | T791I | aCa | aTa | 15 | 15 | B.1.1 | 0.000272 |
S | 791 | T791I | aCa | aTa | 15 | 15 | B.1.2 | 0.000132 |
S | 791 | T791I | aCa | aTa | 14 | 14 | B.1.177.86 | 0.002568 |
S | 791 | T791I | aCa | aTa | 13 | 13 | AY.39 | 0.000321 |
S | 791 | T791I | aCa | aTa | 13 | 13 | B.1.526 | 0.000306 |
S | 791 | T791I | aCa | aTa | 12 | 12 | Q.1 | 0.001516 |
S | 791 | T791I | aCa | aTa | 11 | 11 | B.1.525 | 0.001245 |
S | 791 | T791I | aCa | aTa | 10 | 10 | AY.9.1 | 0.000837 |
S | 791 | T791I | aCa | aTa | 9 | 9 | AY.47 | 0.00028 |
S | 791 | T791I | aCa | aTa | 8 | 8 | AY.30 | 0.003166 |
S | 791 | T791I | aCa | aTa | 7 | 7 | AY.36 | 0.001037 |
S | 791 | T791I | aCa | aTa | 7 | 7 | B.1.1.33 | 0.002946 |
S | 791 | T791I | aCa | aTa | 7 | 7 | B.1.1.519 | 0.000278 |
S | 791 | T791I | aCa | aTa | 7 | 7 | B.1.429 | 0.000165 |
S | 791 | T791I | aCa | aTa | 7 | 7 | B.4 | 0.015453 |
S | 791 | T791I | aCa | aTa | 6 | 6 | AY.117 | 0.000507 |
S | 791 | T791I | aCa | aTa | 6 | 6 | AY.45 | 0.00073 |
S | 791 | T791I | aCa | aTa | 6 | 6 | B.1.524 | 0.008439 |
S | 791 | T791I | aCa | aTa | 6 | 6 | B.1.575 | 0.00182 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.113 | 0.000712 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.120 | 0.000186 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.26 | 0.000142 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.4.5 | 0.000537 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.5.3 | 0.001687 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.74 | 0.000578 |
S | 791 | T791I | aCa | aTa | 5 | 5 | AY.92 | 0.001436 |
S | 791 | T791I | aCa | aTa | 5 | 5 | B | 0.000639 |
S | 791 | T791I | aCa | aTa | 5 | 5 | B.1.160 | 0.000156 |
S | 791 | T791I | aCa | aTa | 5 | 5 | B.1.214.2 | 0.002998 |
S | 791 | T791I | aCa | aTa | 5 | 5 | B.1.243 | 0.000348 |
S | 791 | T791I | aCa | aTa | 5 | 5 | B.1.596 | 0.000436 |
S | 791 | T791I | aCa | aTa | 5 | 5 | B.1.621 | 0.000443 |
S | 791 | T791I | aCa | aTa | 5 | 5 | P.1.14 | 0.000239 |
S | 791 | T791I | aCa | aTa | 4 | 4 | A.21 | 0.01108 |
S | 791 | T791I | aCa | aTa | 4 | 4 | AY.1 | 0.001583 |
S | 791 | T791I | aCa | aTa | 4 | 4 | AY.23 | 0.000279 |
S | 791 | T791I | aCa | aTa | 4 | 4 | AY.33 | 0.000267 |
S | 791 | T791I | aCa | aTa | 4 | 4 | AY.39.1 | 0.000158 |
S | 791 | T791I | aCa | aTa | 4 | 4 | AY.95 | 0.003044 |
S | 791 | T791I | aCa | aTa | 4 | 4 | B.1.240 | 0.000862 |
S | 791 | T791I | aCa | aTa | 4 | 4 | B.1.369 | 0.001141 |
S | 791 | T791I | aCa | aTa | 4 | 4 | B.1.396 | 0.002823 |
S | 791 | T791I | aCa | aTa | 4 | 4 | B.1.427 | 0.000202 |
S | 791 | T791I | aCa | aTa | 4 | 4 | B.1.628 | 0.001409 |
S | 791 | T791I | aCa | aTa | 4 | 4 | C.37 | 0.000464 |
S | 791 | T791I | aCa | aTa | 4 | 4 | P.1.7 | 0.001277 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.106 | 0.001005 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.119 | 0.000106 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.4.2 | 0.000065 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.46 | 0.000312 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.5 | 0.000062 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.7 | 0.000588 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.73 | 0.001996 |
S | 791 | T791I | aCa | aTa | 3 | 3 | AY.75 | 0.000168 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.1.176 | 0.001318 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.1.214 | 0.000166 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.1.318 | 0.000905 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.177.81 | 0.000568 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.177.82 | 0.001432 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.258 | 0.0002 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.265 | 0.003812 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.1.623 | 0.001609 |
S | 791 | T791I | aCa | aTa | 3 | 3 | B.39 | 0.006993 |
S | 791 | T791I | aCa | aTa | 3 | 3 | P.1.15 | 0.000697 |
S | 791 | T791I | aCa | aTa | 2 | 2 | 0.111111 | |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.111 | 0.000366 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.20 | 0.000078 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.24 | 0.000862 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.54 | 0.000191 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.59 | 0.001059 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.6 | 0.000082 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.60 | 0.001876 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.62 | 0.000871 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.69 | 0.000373 |
S | 791 | T791I | aCa | aTa | 2 | 2 | AY.91 | 0.001461 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.1.222 | 0.000408 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.1.434 | 0.000697 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.1.63 | 0.000772 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.208 | 0.08 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.234 | 0.000264 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.466.2 | 0.000782 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.565 | 0.001621 |
S | 791 | T791I | aCa | aTa | 2 | 2 | B.1.617.1 | 0.000258 |
S | 791 | T791I | aCa | aTa | 2 | 2 | D.2 | 0.00015 |
S | 791 | T791I | aCa | aTa | 1 | 1 | A.2.5 | 0.000499 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AE.8 | 0.000489 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.102 | 0.000027 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.114 | 0.000231 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.120.1 | 0.000321 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.13 | 0.000161 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.2 | 0.000356 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.3.1 | 0.000085 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.34.1 | 0.00051 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.46.2 | 0.000635 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.55 | 0.000917 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.67 | 0.000464 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.68 | 0.000274 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.7.2 | 0.000559 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.75.1 | 0.00018 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.9.2.1 | 0.001976 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.98.1 | 0.000048 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.99 | 0.001049 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AY.99.2 | 0.000092 |
S | 791 | T791I | aCa | aTa | 1 | 1 | AZ.2 | 0.000821 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.1.25 | 0.000569 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.1.255 | 0.00303 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.1.291 | 0.000742 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.1.333 | 0.001076 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.1.354 | 0.004386 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.1.461 | 0.012048 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.111 | 0.001175 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.126 | 0.001276 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.177.24 | 0.001295 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.177.45 | 0.000381 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.177.57 | 0.000281 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.177.65 | 0.000665 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.221 | 0.000071 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.239 | 0.001221 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.258.17 | 0.000104 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.280 | 0.007143 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.351.2 | 0.000303 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.36 | 0.000146 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.362 | 0.001541 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.367 | 0.000792 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.375 | 0.00082 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.400 | 0.000429 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.409 | 0.000781 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.560 | 0.00463 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.576 | 0.000907 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.596.1 | 0.009346 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.1.627 | 0.00202 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.10 | 0.008264 |
S | 791 | T791I | aCa | aTa | 1 | 1 | B.6 | 0.00091 |
S | 791 | T791I | aCa | aTa | 1 | 1 | C.36 | 0.000911 |
S | 791 | T791I | aCa | aTa | 1 | 1 | C.8 | 0.004464 |
S | 791 | T791I | aCa | aTa | 1 | 1 | P.1.10 | 0.000269 |
S | 791 | T791I | aCa | aTa | 1 | 1 | P.1.17 | 0.000162 |
S | 791 | T791I | aCa | aTa | 1 | 1 | P.3 | 0.001595 |
S | 791 | T791I | aCa | aTa | 1 | 1 | Q.2 | 0.000613 |
S | 791 | T791I | aCa | aTa | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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