CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 747 | T747I | nonsyn | aCt | aTt | 3088 | 3088 | 1 | 23801-23803 |
Details of the mutation T747I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 747 | T747I | aCt | aTt | 3088 | 3088 | All | 0.000591 |
S | 747 | T747I | aCt | aTt | 1134 | 1134 | B.1.1.7 | 0.001015 |
S | 747 | T747I | aCt | aTt | 383 | 383 | AY.4 | 0.000596 |
S | 747 | T747I | aCt | aTt | 239 | 239 | AY.103 | 0.001484 |
S | 747 | T747I | aCt | aTt | 140 | 140 | B.1.2 | 0.001233 |
S | 747 | T747I | aCt | aTt | 122 | 122 | B.1.617.2 | 0.000459 |
S | 747 | T747I | aCt | aTt | 93 | 93 | B.1.221 | 0.006606 |
S | 747 | T747I | aCt | aTt | 61 | 61 | B.1.1.222 | 0.012444 |
S | 747 | T747I | aCt | aTt | 55 | 55 | B.1.526 | 0.001293 |
S | 747 | T747I | aCt | aTt | 52 | 52 | AY.43 | 0.00023 |
S | 747 | T747I | aCt | aTt | 44 | 44 | AY.44 | 0.000268 |
S | 747 | T747I | aCt | aTt | 37 | 37 | AY.14 | 0.003256 |
S | 747 | T747I | aCt | aTt | 36 | 36 | AY.45 | 0.004381 |
S | 747 | T747I | aCt | aTt | 33 | 33 | B.1.1.519 | 0.00131 |
S | 747 | T747I | aCt | aTt | 29 | 29 | B.1 | 0.000266 |
S | 747 | T747I | aCt | aTt | 29 | 29 | B.1.1.72 | 0.878788 |
S | 747 | T747I | aCt | aTt | 26 | 26 | N.2 | 1 |
S | 747 | T747I | aCt | aTt | 25 | 25 | B.1.429 | 0.000588 |
S | 747 | T747I | aCt | aTt | 25 | 25 | B.1.551 | 0.032258 |
S | 747 | T747I | aCt | aTt | 21 | 21 | AY.102 | 0.000557 |
S | 747 | T747I | aCt | aTt | 21 | 21 | AY.7 | 0.004116 |
S | 747 | T747I | aCt | aTt | 20 | 20 | B.1.1 | 0.000363 |
S | 747 | T747I | aCt | aTt | 19 | 19 | B.1.177 | 0.00025 |
S | 747 | T747I | aCt | aTt | 18 | 18 | AY.74 | 0.002082 |
S | 747 | T747I | aCt | aTt | 18 | 18 | B.1.234 | 0.002375 |
S | 747 | T747I | aCt | aTt | 14 | 14 | AY.25 | 0.000084 |
S | 747 | T747I | aCt | aTt | 13 | 13 | AY.26 | 0.000368 |
S | 747 | T747I | aCt | aTt | 12 | 12 | AY.120 | 0.000446 |
S | 747 | T747I | aCt | aTt | 12 | 12 | AY.3 | 0.000119 |
S | 747 | T747I | aCt | aTt | 12 | 12 | AY.75 | 0.000672 |
S | 747 | T747I | aCt | aTt | 11 | 11 | AY.119 | 0.000388 |
S | 747 | T747I | aCt | aTt | 11 | 11 | AY.84 | 0.004812 |
S | 747 | T747I | aCt | aTt | 11 | 11 | B.1.351 | 0.000327 |
S | 747 | T747I | aCt | aTt | 11 | 11 | P.1 | 0.000173 |
S | 747 | T747I | aCt | aTt | 10 | 10 | B.1.177.86 | 0.001835 |
S | 747 | T747I | aCt | aTt | 10 | 10 | B.1.561 | 0.00397 |
S | 747 | T747I | aCt | aTt | 9 | 9 | AY.116.1 | 0.002803 |
S | 747 | T747I | aCt | aTt | 7 | 7 | B.1.258 | 0.000466 |
S | 747 | T747I | aCt | aTt | 6 | 6 | AY.110 | 0.000676 |
S | 747 | T747I | aCt | aTt | 6 | 6 | AY.118 | 0.000376 |
S | 747 | T747I | aCt | aTt | 6 | 6 | AY.121 | 0.000812 |
S | 747 | T747I | aCt | aTt | 6 | 6 | AY.29 | 0.000095 |
S | 747 | T747I | aCt | aTt | 6 | 6 | B.1.160 | 0.000187 |
S | 747 | T747I | aCt | aTt | 6 | 6 | B.1.596 | 0.000523 |
S | 747 | T747I | aCt | aTt | 6 | 6 | C.37 | 0.000696 |
S | 747 | T747I | aCt | aTt | 5 | 5 | AY.100 | 0.00023 |
S | 747 | T747I | aCt | aTt | 5 | 5 | AY.20 | 0.000194 |
S | 747 | T747I | aCt | aTt | 5 | 5 | AY.39 | 0.000124 |
S | 747 | T747I | aCt | aTt | 5 | 5 | AY.4.2 | 0.000108 |
S | 747 | T747I | aCt | aTt | 5 | 5 | AY.9.2 | 0.000184 |
S | 747 | T747I | aCt | aTt | 5 | 5 | B.1.324 | 0.008026 |
S | 747 | T747I | aCt | aTt | 5 | 5 | B.1.36 | 0.00073 |
S | 747 | T747I | aCt | aTt | 5 | 5 | B.1.469 | 0.018051 |
S | 747 | T747I | aCt | aTt | 5 | 5 | B.1.580 | 0.020325 |
S | 747 | T747I | aCt | aTt | 4 | 4 | AY.106 | 0.00134 |
S | 747 | T747I | aCt | aTt | 4 | 4 | B.1.1.216 | 0.003562 |
S | 747 | T747I | aCt | aTt | 4 | 4 | B.1.1.416 | 0.00362 |
S | 747 | T747I | aCt | aTt | 4 | 4 | B.1.177.55 | 0.009324 |
S | 747 | T747I | aCt | aTt | 4 | 4 | B.1.575 | 0.001214 |
S | 747 | T747I | aCt | aTt | 4 | 4 | B.1.621 | 0.000354 |
S | 747 | T747I | aCt | aTt | 4 | 4 | P.1.7 | 0.001277 |
S | 747 | T747I | aCt | aTt | 3 | 3 | AY.27 | 0.000194 |
S | 747 | T747I | aCt | aTt | 3 | 3 | AY.32 | 0.001597 |
S | 747 | T747I | aCt | aTt | 3 | 3 | AY.54 | 0.000286 |
S | 747 | T747I | aCt | aTt | 3 | 3 | AY.79 | 0.003632 |
S | 747 | T747I | aCt | aTt | 3 | 3 | AY.98.1 | 0.000145 |
S | 747 | T747I | aCt | aTt | 3 | 3 | AY.99.2 | 0.000276 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.1.157 | 0.00274 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.1.317 | 0.001235 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.1.48 | 0.008621 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.1.518 | 0.018987 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.177.8 | 0.002257 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.427 | 0.000151 |
S | 747 | T747I | aCt | aTt | 3 | 3 | B.1.451 | 0.02459 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.19 | 0.002281 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.39.1 | 0.000079 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.46 | 0.000208 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.47 | 0.000062 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.5 | 0.000041 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.61 | 0.00021 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.62 | 0.000871 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.75.1 | 0.000361 |
S | 747 | T747I | aCt | aTt | 2 | 2 | AY.98 | 0.000158 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B | 0.000256 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.1.28 | 0.000622 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.1.294 | 0.002532 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.349 | 0.00143 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.36.10 | 0.009569 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.36.19 | 0.018519 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.369 | 0.00057 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.435 | 0.022727 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.465 | 0.007605 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.582 | 0.000981 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.628 | 0.000705 |
S | 747 | T747I | aCt | aTt | 2 | 2 | B.1.637 | 0.000146 |
S | 747 | T747I | aCt | aTt | 2 | 2 | P.1.14 | 0.000096 |
S | 747 | T747I | aCt | aTt | 2 | 2 | P.1.15 | 0.000465 |
S | 747 | T747I | aCt | aTt | 2 | 2 | P.2 | 0.000373 |
S | 747 | T747I | aCt | aTt | 1 | 1 | A.2 | 0.000662 |
S | 747 | T747I | aCt | aTt | 1 | 1 | A.2.2 | 0.001689 |
S | 747 | T747I | aCt | aTt | 1 | 1 | A.5 | 0.001923 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.1 | 0.000396 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.107 | 0.000466 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.116 | 0.000287 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.3.1 | 0.000085 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.4.4 | 0.000409 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.4.5 | 0.000107 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.42 | 0.00004 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.46.2 | 0.000635 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.46.6 | 0.000072 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.55 | 0.000917 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.68 | 0.000274 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.7.2 | 0.000559 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.85 | 0.000427 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.88 | 0.000884 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.9 | 0.000068 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.93 | 0.000273 |
S | 747 | T747I | aCt | aTt | 1 | 1 | AY.94 | 0.000443 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.10 | 0.001115 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.214 | 0.000055 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.265 | 0.003155 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.280 | 0.003086 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.286 | 0.002899 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.302 | 0.002075 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.306 | 0.000438 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.309 | 0.005848 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.318 | 0.000302 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.39 | 0.00051 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.526 | 0.003546 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.1.63 | 0.000386 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.110.3 | 0.000718 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.116 | 0.011628 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.126 | 0.001276 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.177.21 | 0.000076 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.177.42 | 0.000894 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.177.58 | 0.001332 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.199 | 0.004132 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.201 | 0.005682 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.206 | 0.000816 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.210 | 0.002132 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.232 | 0.000537 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.258.16 | 0.001637 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.3 | 0.002618 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.338 | 0.008621 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.36.18 | 0.00042 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.389 | 0.001002 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.395 | 0.007042 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.400 | 0.000429 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.421 | 0.007463 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.438.1 | 0.000107 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.471 | 0.002732 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.503 | 0.002488 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.571 | 0.009709 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.595 | 0.000261 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.617.1 | 0.000129 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.619.1 | 0.000641 |
S | 747 | T747I | aCt | aTt | 1 | 1 | B.1.627 | 0.00202 |
S | 747 | T747I | aCt | aTt | 1 | 1 | C.18 | 0.002591 |
S | 747 | T747I | aCt | aTt | 1 | 1 | P.1.12 | 0.000484 |
S | 747 | T747I | aCt | aTt | 1 | 1 | Q.1 | 0.000126 |
S | 747 | T747I | aCt | aTt | 1 | 1 | Q.3 | 0.000145 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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