CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = T732A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	732	T732A		nonsyn	Acc	Gcc	30964	30891	0.997642	23756-23758
S	732	T732A		nonsyn	AcC	GcT	30964	72	0.00232528	23756-23758
S	732	T732A		nonsyn	AcC	GcG	30964	1	0.0000322956	23756-23758

Details of the mutation T732A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	732	T732A	Acc	Gcc	30891	30964	All	0.005908
S	732	T732A	AcC	GcT	72	30964	All	0.000014
S	732	T732A	AcC	GcG	1	30964	All	0
S	732	T732A	Acc	Gcc	24680	24708	B.1.1.519	0.980065
S	732	T732A	AcC	GcT	28	24708	B.1.1.519	0.001112
S	732	T732A	Acc	Gcc	4864	4884	B.1.1.222	0.992248
S	732	T732A	AcC	GcT	19	4884	B.1.1.222	0.003876
S	732	T732A	AcC	GcG	1	4884	B.1.1.222	0.000204
S	732	T732A	Acc	Gcc	391	392	B.1	0.003581
S	732	T732A	AcC	GcT	1	392	B.1	0.000009
S	732	T732A	Acc	Gcc	193	193	B.1.1	0.003501
S	732	T732A	Acc	Gcc	146	146	B.1.1.517	0.993197
S	732	T732A	Acc	Gcc	113	113	B.1.1.322	0.991228
S	732	T732A	Acc	Gcc	109	109	B.1.429	0.002565
S	732	T732A	Acc	Gcc	53	53	B.1.2	0.000467
S	732	T732A	Acc	Gcc	45	45	AY.4	0.00007
S	732	T732A	Acc	Gcc	22	44	B.1.1.418	0.5
S	732	T732A	AcC	GcT	22	44	B.1.1.418	0.5
S	732	T732A	Acc	Gcc	31	31	B.1.177	0.000408
S	732	T732A	Acc	Gcc	28	28	B.1.1.7	0.000025
S	732	T732A	Acc	Gcc	23	23	B.1.1.306	0.010083
S	732	T732A	Acc	Gcc	17	17	B.1.179	0.06391
S	732	T732A	Acc	Gcc	13	13	AY.5.3	0.004386
S	732	T732A	Acc	Gcc	11	11	B.1.160	0.000343
S	732	T732A	Acc	Gcc	9	9	AY.98.1	0.000436
S	732	T732A	Acc	Gcc	9	9	B.1.1.28	0.002801
S	732	T732A	Acc	Gcc	8	8	B.1.596	0.000697
S	732	T732A	Acc	Gcc	8	8	B.1.617.2	0.00003
S	732	T732A	Acc	Gcc	6	6	AY.43	0.000027
S	732	T732A	Acc	Gcc	6	6	B.1.545	0.086957
S	732	T732A	Acc	Gcc	6	6	P.1	0.000095
S	732	T732A	Acc	Gcc	5	5	B.1.351	0.000149
S	732	T732A	Acc	Gcc	4	4	AY.103	0.000025
S	732	T732A	Acc	Gcc	4	4	AY.25	0.000024
S	732	T732A	Acc	Gcc	4	4	B.1.311	0.001098
S	732	T732A	Acc	Gcc	4	4	B.1.609	0.001918
S	732	T732A	Acc	Gcc	3	3	AY.26	0.000085
S	732	T732A	Acc	Gcc	3	3	AY.3	0.00003
S	732	T732A	Acc	Gcc	3	3	AY.67	0.001393
S	732	T732A	Acc	Gcc	3	3	B.1.1.189	0.004539
S	732	T732A	Acc	Gcc	3	3	B.1.1.526	0.010638
S	732	T732A	Acc	Gcc	3	3	B.1.530	0.021429
S	732	T732A	Acc	Gcc	3	3	B.6	0.00273
S	732	T732A	AcC	GcT	2	2		0.111111
S	732	T732A	Acc	Gcc	2	2	A.27	0.003311
S	732	T732A	Acc	Gcc	2	2	AY.44	0.000012
S	732	T732A	Acc	Gcc	2	2	B.1.1.236	0.013793
S	732	T732A	Acc	Gcc	2	2	B.1.1.37	0.000386
S	732	T732A	Acc	Gcc	2	2	B.1.1.372	0.001377
S	732	T732A	Acc	Gcc	2	2	B.1.1.521	0.010695
S	732	T732A	Acc	Gcc	2	2	B.1.234	0.000264
S	732	T732A	Acc	Gcc	2	2	B.1.349	0.00143
S	732	T732A	Acc	Gcc	2	2	B.1.595	0.000522
S	732	T732A	Acc	Gcc	2	2	B.1.78	0.017094
S	732	T732A	Acc	Gcc	1	1	A	0.000387
S	732	T732A	Acc	Gcc	1	1	A.1	0.000282
S	732	T732A	Acc	Gcc	1	1	AU.3	0.00211
S	732	T732A	Acc	Gcc	1	1	AY.100	0.000046
S	732	T732A	Acc	Gcc	1	1	AY.102	0.000027
S	732	T732A	Acc	Gcc	1	1	AY.121	0.000135
S	732	T732A	Acc	Gcc	1	1	AY.36	0.000148
S	732	T732A	Acc	Gcc	1	1	AY.38	0.000499
S	732	T732A	Acc	Gcc	1	1	AY.46	0.000104
S	732	T732A	Acc	Gcc	1	1	AY.46.4	0.000165
S	732	T732A	Acc	Gcc	1	1	AY.5	0.000021
S	732	T732A	Acc	Gcc	1	1	B	0.000128
S	732	T732A	Acc	Gcc	1	1	B.1.1.160	0.02381
S	732	T732A	Acc	Gcc	1	1	B.1.1.220	0.001859
S	732	T732A	Acc	Gcc	1	1	B.1.1.261	0.008621
S	732	T732A	Acc	Gcc	1	1	B.1.1.269	0.001353
S	732	T732A	Acc	Gcc	1	1	B.1.1.33	0.000421
S	732	T732A	Acc	Gcc	1	1	B.1.1.500	0.02
S	732	T732A	Acc	Gcc	1	1	B.1.1.54	0.003021
S	732	T732A	Acc	Gcc	1	1	B.1.1.98	0.018519
S	732	T732A	Acc	Gcc	1	1	B.1.126	0.001276
S	732	T732A	Acc	Gcc	1	1	B.1.157	0.002985
S	732	T732A	Acc	Gcc	1	1	B.1.206	0.000816
S	732	T732A	Acc	Gcc	1	1	B.1.210	0.002132
S	732	T732A	Acc	Gcc	1	1	B.1.239	0.001221
S	732	T732A	Acc	Gcc	1	1	B.1.240	0.000216
S	732	T732A	Acc	Gcc	1	1	B.1.243	0.00007
S	732	T732A	Acc	Gcc	1	1	B.1.258	0.000067
S	732	T732A	Acc	Gcc	1	1	B.1.279	0.000514
S	732	T732A	Acc	Gcc	1	1	B.1.354	0.043478
S	732	T732A	Acc	Gcc	1	1	B.1.36.29	0.000517
S	732	T732A	Acc	Gcc	1	1	B.1.362	0.001541
S	732	T732A	Acc	Gcc	1	1	B.1.427	0.00005
S	732	T732A	Acc	Gcc	1	1	B.1.462	0.007246
S	732	T732A	Acc	Gcc	1	1	B.1.525	0.000113
S	732	T732A	Acc	Gcc	1	1	B.1.577	0.000687
S	732	T732A	Acc	Gcc	1	1	B.1.621	0.000089
S	732	T732A	Acc	Gcc	1	1	B.1.637	0.000073

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.