CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = T723I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	723	T723I		nonsyn	aCc	aTc	2911	2877	0.98832	23729-23731
S	723	T723I		nonsyn	aCC	aTT	2911	34	0.0116798	23729-23731

Details of the mutation T723I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	723	T723I	aCc	aTc	2877	2911	All	0.00055
S	723	T723I	aCC	aTT	34	2911	All	0.000007
S	723	T723I	aCc	aTc	994	994	B.1.389	0.995992
S	723	T723I	aCc	aTc	832	833	B.1.1.7	0.000745
S	723	T723I	aCC	aTT	1	833	B.1.1.7	0.000001
S	723	T723I	aCc	aTc	108	108	B.1	0.000989
S	723	T723I	aCc	aTc	78	95	B.1.526	0.001833
S	723	T723I	aCC	aTT	17	95	B.1.526	0.0004
S	723	T723I	aCc	aTc	79	79	B.1.2	0.000696
S	723	T723I	aCc	aTc	70	70	B.1.617.2	0.000264
S	723	T723I	aCc	aTc	66	66	AY.103	0.00041
S	723	T723I	aCc	aTc	60	60	B.1.1.284	0.006444
S	723	T723I	aCc	aTc	51	51	AY.25	0.000307
S	723	T723I	aCc	aTc	46	46	AY.4	0.000072
S	723	T723I	aCc	aTc	44	44	P.1	0.000693
S	723	T723I	aCc	aTc	42	42	AY.44	0.000256
S	723	T723I	aCc	aTc	38	38	B.1.1.519	0.001509
S	723	T723I	aCc	aTc	31	31	B.1.429	0.000729
S	723	T723I	aCc	aTc	30	30	AY.3	0.000298
S	723	T723I	aCc	aTc	29	29	B.1.637	0.002119
S	723	T723I	aCc	aTc	17	17	B.1.1.214	0.000943
S	723	T723I	aCc	aTc	15	15	AY.37	0.004741
S	723	T723I	aCc	aTc	12	12	AY.26	0.00034
S	723	T723I	aCc	aTc	12	12	AY.39	0.000297
S	723	T723I	aCc	aTc	9	9	B.1.243	0.000626
S	723	T723I	aCc	aTc	9	9	B.1.427	0.000454
S	723	T723I	aCc	aTc	9	9	B.1.575	0.002731
S	723	T723I	aCc	aTc	9	9	Q.3	0.001305
S	723	T723I	aCc	aTc	9	9	R.1	0.00081
S	723	T723I	aCc	aTc	8	8	AY.47	0.000249
S	723	T723I	aCc	aTc	8	8	B.1.351	0.000238
S	723	T723I	aCc	aTc	7	7	AY.118	0.000439
S	723	T723I	aCc	aTc	7	7	AY.43	0.000031
S	723	T723I	aCc	aTc	7	7	B.1.1	0.000127
S	723	T723I	aCc	aTc	7	7	B.1.596	0.00061
S	723	T723I	aCc	aTc	7	7	B.1.623	0.003755
S	723	T723I	aCc	aTc	6	6	B.1.1.523	0.009375
S	723	T723I	aCc	aTc	6	6	B.1.525	0.000679
S	723	T723I	aCc	aTc	6	6	B.1.564	0.002555
S	723	T723I	aCC	aTT	6	6	C.37	0.000696
S	723	T723I	aCc	aTc	5	5	AY.20	0.000194
S	723	T723I	aCc	aTc	5	5	AY.39.1	0.000198
S	723	T723I	aCc	aTc	5	5	B.1.311	0.001373
S	723	T723I	aCc	aTc	4	4	AY.75	0.000224
S	723	T723I	aCc	aTc	4	4	B.1.621	0.000354
S	723	T723I	aCC	aTT	4	4	C.38	0.032258
S	723	T723I	aCc	aTc	4	4	P.1.17	0.000647
S	723	T723I	aCc	aTc	3	3	AY.117	0.000254
S	723	T723I	aCc	aTc	3	3	AY.119	0.000106
S	723	T723I	aCc	aTc	3	3	AY.27	0.000194
S	723	T723I	aCc	aTc	3	3	AY.3.1	0.000256
S	723	T723I	aCc	aTc	3	3	B.1.221	0.000213
S	723	T723I	aCc	aTc	3	3	P.1.13	0.002695
S	723	T723I	aCC	aTT	2	2		0.111111
S	723	T723I	aCc	aTc	2	2	AY.113	0.000285
S	723	T723I	aCc	aTc	2	2	AY.34	0.000194
S	723	T723I	aCc	aTc	2	2	B.1.1.128	0.014184
S	723	T723I	aCc	aTc	2	2	B.1.1.318	0.000604
S	723	T723I	aCc	aTc	2	2	B.1.1.37	0.000386
S	723	T723I	aCc	aTc	2	2	B.1.1.486	0.003155
S	723	T723I	aCc	aTc	2	2	B.1.111	0.00235
S	723	T723I	aCc	aTc	2	2	B.1.177	0.000026
S	723	T723I	aCc	aTc	2	2	B.1.628	0.000705
S	723	T723I	aCC	aTT	2	2	C.36.3.1	0.005435
S	723	T723I	aCc	aTc	2	2	P.1.10	0.000539
S	723	T723I	aCc	aTc	1	1	A.1	0.000282
S	723	T723I	aCc	aTc	1	1	A.2.5	0.000499
S	723	T723I	aCc	aTc	1	1	AY.10	0.00053
S	723	T723I	aCc	aTc	1	1	AY.107	0.000466
S	723	T723I	aCc	aTc	1	1	AY.110	0.000113
S	723	T723I	aCc	aTc	1	1	AY.114	0.000231
S	723	T723I	aCc	aTc	1	1	AY.12	0.000316
S	723	T723I	aCc	aTc	1	1	AY.121	0.000135
S	723	T723I	aCc	aTc	1	1	AY.16	0.00038
S	723	T723I	aCc	aTc	1	1	AY.2	0.000356
S	723	T723I	aCc	aTc	1	1	AY.29	0.000016
S	723	T723I	aCc	aTc	1	1	AY.38	0.000499
S	723	T723I	aCc	aTc	1	1	AY.4.2	0.000022
S	723	T723I	aCc	aTc	1	1	AY.4.4	0.000409
S	723	T723I	aCc	aTc	1	1	AY.42	0.00004
S	723	T723I	aCc	aTc	1	1	AY.5	0.000021
S	723	T723I	aCc	aTc	1	1	AY.54	0.000095
S	723	T723I	aCc	aTc	1	1	AY.66	0.00107
S	723	T723I	aCc	aTc	1	1	AY.68	0.000274
S	723	T723I	aCc	aTc	1	1	AY.98.1	0.000048
S	723	T723I	aCc	aTc	1	1	AZ.3	0.00152
S	723	T723I	aCc	aTc	1	1	B.1.1.222	0.000204
S	723	T723I	aCc	aTc	1	1	B.1.1.269	0.001353
S	723	T723I	aCc	aTc	1	1	B.1.1.28	0.000311
S	723	T723I	aCc	aTc	1	1	B.1.1.306	0.000438
S	723	T723I	aCc	aTc	1	1	B.1.1.348	0.000796
S	723	T723I	aCc	aTc	1	1	B.1.1.464	0.001473
S	723	T723I	aCc	aTc	1	1	B.1.177.7	0.000165
S	723	T723I	aCc	aTc	1	1	B.1.214.2	0.0006
S	723	T723I	aCc	aTc	1	1	B.1.349	0.000715
S	723	T723I	aCc	aTc	1	1	B.1.396	0.000706
S	723	T723I	aCc	aTc	1	1	B.1.397	0.004854
S	723	T723I	aCc	aTc	1	1	B.1.438.1	0.000107
S	723	T723I	aCc	aTc	1	1	B.1.577	0.000687
S	723	T723I	aCc	aTc	1	1	B.1.588	0.00091
S	723	T723I	aCc	aTc	1	1	B.1.621.1	0.000506
S	723	T723I	aCc	aTc	1	1	B.1.636	0.006711
S	723	T723I	aCc	aTc	1	1	B.35	0.007812
S	723	T723I	aCC	aTT	1	1	C.1.2	0.004255
S	723	T723I	aCC	aTT	1	1	C.36.3	0.000567
S	723	T723I	aCc	aTc	1	1	P.1.1	0.000318
S	723	T723I	aCc	aTc	1	1	P.1.12	0.000484
S	723	T723I	aCc	aTc	1	1	P.2	0.000187
S	723	T723I	aCc	aTc	1	1	Q.4	0.000455
S	723	T723I	aCc	aTc	1	1	Q.5	0.016949
S	723	T723I	aCc	aTc	1	1	Q.6	0.006623

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.