CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 719 | T719I | nonsyn | aCt | aTt | 11969 | 11969 | 1 | 23717-23719 |
Details of the mutation T719I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 719 | T719I | aCt | aTt | 11969 | 11969 | All | 0.002289 |
S | 719 | T719I | aCt | aTt | 10272 | 10272 | AY.42 | 0.413244 |
S | 719 | T719I | aCt | aTt | 463 | 463 | B.1.1.7 | 0.000414 |
S | 719 | T719I | aCt | aTt | 197 | 197 | B.1.448 | 0.51706 |
S | 719 | T719I | aCt | aTt | 150 | 150 | AY.103 | 0.000931 |
S | 719 | T719I | aCt | aTt | 87 | 87 | AY.4 | 0.000135 |
S | 719 | T719I | aCt | aTt | 67 | 67 | B.1.617.2 | 0.000252 |
S | 719 | T719I | aCt | aTt | 51 | 51 | B.1.1 | 0.000925 |
S | 719 | T719I | aCt | aTt | 49 | 49 | B.1.177 | 0.000645 |
S | 719 | T719I | aCt | aTt | 47 | 47 | AY.43 | 0.000208 |
S | 719 | T719I | aCt | aTt | 46 | 46 | B.1.2 | 0.000405 |
S | 719 | T719I | aCt | aTt | 43 | 43 | AY.44 | 0.000262 |
S | 719 | T719I | aCt | aTt | 27 | 27 | B.1.351 | 0.000803 |
S | 719 | T719I | aCt | aTt | 26 | 26 | AY.25 | 0.000156 |
S | 719 | T719I | aCt | aTt | 25 | 25 | B.1 | 0.000229 |
S | 719 | T719I | aCt | aTt | 22 | 22 | AY.26 | 0.000623 |
S | 719 | T719I | aCt | aTt | 22 | 22 | AY.29 | 0.000347 |
S | 719 | T719I | aCt | aTt | 17 | 17 | AY.98.1 | 0.000823 |
S | 719 | T719I | aCt | aTt | 15 | 15 | AY.100 | 0.00069 |
S | 719 | T719I | aCt | aTt | 15 | 15 | AY.3 | 0.000149 |
S | 719 | T719I | aCt | aTt | 14 | 14 | AY.102 | 0.000371 |
S | 719 | T719I | aCt | aTt | 11 | 11 | AY.41 | 0.003233 |
S | 719 | T719I | aCt | aTt | 10 | 10 | AY.39 | 0.000247 |
S | 719 | T719I | aCt | aTt | 10 | 10 | B.1.243 | 0.000696 |
S | 719 | T719I | aCt | aTt | 10 | 10 | B.1.596 | 0.000871 |
S | 719 | T719I | aCt | aTt | 10 | 10 | P.2 | 0.001866 |
S | 719 | T719I | aCt | aTt | 7 | 7 | AY.110 | 0.000789 |
S | 719 | T719I | aCt | aTt | 7 | 7 | AY.20 | 0.000272 |
S | 719 | T719I | aCt | aTt | 7 | 7 | B.1.422 | 0.005686 |
S | 719 | T719I | aCt | aTt | 7 | 7 | D.2 | 0.000525 |
S | 719 | T719I | aCt | aTt | 7 | 7 | P.1 | 0.00011 |
S | 719 | T719I | aCt | aTt | 6 | 6 | AY.9.1 | 0.000502 |
S | 719 | T719I | aCt | aTt | 6 | 6 | B.1.240 | 0.001293 |
S | 719 | T719I | aCt | aTt | 5 | 5 | AY.34 | 0.000485 |
S | 719 | T719I | aCt | aTt | 5 | 5 | AY.45 | 0.000608 |
S | 719 | T719I | aCt | aTt | 5 | 5 | AY.9 | 0.000338 |
S | 719 | T719I | aCt | aTt | 5 | 5 | B.1.258 | 0.000333 |
S | 719 | T719I | aCt | aTt | 4 | 4 | AY.4.2 | 0.000087 |
S | 719 | T719I | aCt | aTt | 4 | 4 | AY.46.4 | 0.000658 |
S | 719 | T719I | aCt | aTt | 4 | 4 | AY.5.3 | 0.00135 |
S | 719 | T719I | aCt | aTt | 4 | 4 | AY.54 | 0.000381 |
S | 719 | T719I | aCt | aTt | 4 | 4 | B.1.1.519 | 0.000159 |
S | 719 | T719I | aCt | aTt | 4 | 4 | B.1.369 | 0.001141 |
S | 719 | T719I | aCt | aTt | 4 | 4 | B.1.429 | 0.000094 |
S | 719 | T719I | aCt | aTt | 4 | 4 | C.23 | 0.023256 |
S | 719 | T719I | aCt | aTt | 4 | 4 | C.37 | 0.000464 |
S | 719 | T719I | aCt | aTt | 4 | 4 | P.1.14 | 0.000191 |
S | 719 | T719I | aCt | aTt | 3 | 3 | AY.119 | 0.000106 |
S | 719 | T719I | aCt | aTt | 3 | 3 | AY.47 | 0.000093 |
S | 719 | T719I | aCt | aTt | 3 | 3 | AY.5 | 0.000062 |
S | 719 | T719I | aCt | aTt | 3 | 3 | AY.61 | 0.000314 |
S | 719 | T719I | aCt | aTt | 3 | 3 | AY.98 | 0.000237 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.160 | 0.000094 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.177.10 | 0.002634 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.36 | 0.000438 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.375 | 0.002459 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.526 | 0.000071 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.577 | 0.002062 |
S | 719 | T719I | aCt | aTt | 3 | 3 | B.1.637 | 0.000219 |
S | 719 | T719I | aCt | aTt | 3 | 3 | Q.1 | 0.000379 |
S | 719 | T719I | aCt | aTt | 2 | 2 | A.2.5 | 0.000998 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.116 | 0.000574 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.121 | 0.000271 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.23 | 0.000139 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.3.1 | 0.000171 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.33 | 0.000134 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.39.1 | 0.000079 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.4.2.1 | 0.000298 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.73 | 0.001331 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.74 | 0.000231 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.75 | 0.000112 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.91 | 0.001461 |
S | 719 | T719I | aCt | aTt | 2 | 2 | AY.99.2 | 0.000184 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B | 0.000256 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.1.409 | 0.005666 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.177.24 | 0.002591 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.177.43 | 0.002954 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.221 | 0.000142 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.36.19 | 0.018519 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.36.8 | 0.002 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.427 | 0.000101 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.525 | 0.000226 |
S | 719 | T719I | aCt | aTt | 2 | 2 | B.1.618 | 0.008065 |
S | 719 | T719I | aCt | aTt | 2 | 2 | C.36 | 0.001821 |
S | 719 | T719I | aCt | aTt | 2 | 2 | P.1.12 | 0.000968 |
S | 719 | T719I | aCt | aTt | 2 | 2 | R.1 | 0.00018 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AE.5 | 0.018519 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.106 | 0.000335 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.113 | 0.000142 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.118 | 0.000063 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.120.2 | 0.001285 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.16 | 0.00038 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.23.1 | 0.000417 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.32 | 0.000532 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.34.1 | 0.00051 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.35 | 0.000233 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.37 | 0.000316 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.40 | 0.000964 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.46 | 0.000104 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.46.6 | 0.000072 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.51 | 0.000909 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.53 | 0.000288 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.59 | 0.00053 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.6 | 0.000041 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.7.2 | 0.000559 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.75.1 | 0.00018 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.79 | 0.001211 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.9.2 | 0.000037 |
S | 719 | T719I | aCt | aTt | 1 | 1 | AY.99 | 0.001049 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.153 | 0.001095 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.176 | 0.000439 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.241 | 0.00207 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.265 | 0.003155 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.269 | 0.001353 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.306 | 0.000438 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.33 | 0.000421 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.348 | 0.000796 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.355 | 0.015385 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.39 | 0.00051 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.464 | 0.001473 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.63 | 0.000386 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.1.70 | 0.000341 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.110 | 0.004525 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.147 | 0.000756 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.151 | 0.011111 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.167 | 0.007812 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.177.21 | 0.000076 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.177.4 | 0.000211 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.177.41 | 0.0025 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.177.7 | 0.000165 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.177.75 | 0.001041 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.177.81 | 0.000189 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.206 | 0.000816 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.279 | 0.000514 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.36.29 | 0.000517 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.36.38 | 0.001642 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.400 | 0.000429 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.416.1 | 0.001563 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.426 | 0.001009 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.470 | 0.001404 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.509 | 0.000866 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.561 | 0.000397 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.609 | 0.000479 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.621 | 0.000089 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.627 | 0.00202 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.628 | 0.000352 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.630 | 0.005236 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.1.93 | 0.000934 |
S | 719 | T719I | aCt | aTt | 1 | 1 | B.61 | 0.005747 |
S | 719 | T719I | aCt | aTt | 1 | 1 | C.35 | 0.000774 |
S | 719 | T719I | aCt | aTt | 1 | 1 | P.1.17 | 0.000162 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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