CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 51 | T51I | nonsyn | aCt | aTt | 6429 | 6427 | 0.999689 | 21713-21715 | |
S | 51 | T51I | nonsyn | aCT | aTC | 6429 | 2 | 0.00031109 | 21713-21715 |
Details of the mutation T51I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 51 | T51I | aCt | aTt | 6427 | 6429 | All | 0.001229 |
S | 51 | T51I | aCT | aTC | 2 | 6429 | All | 0 |
S | 51 | T51I | aCt | aTt | 4295 | 4295 | AY.120 | 0.159683 |
S | 51 | T51I | aCt | aTt | 825 | 825 | B.1.177.62 | 0.983313 |
S | 51 | T51I | aCt | aTt | 234 | 234 | B.1.177 | 0.003081 |
S | 51 | T51I | aCt | aTt | 137 | 137 | B.1.617.2 | 0.000516 |
S | 51 | T51I | aCt | aTt | 116 | 116 | B.1.1.7 | 0.000104 |
S | 51 | T51I | aCt | aTt | 106 | 106 | AY.4 | 0.000165 |
S | 51 | T51I | aCt | aTt | 82 | 82 | AY.43 | 0.000363 |
S | 51 | T51I | aCt | aTt | 40 | 40 | AY.44 | 0.000243 |
S | 51 | T51I | aCt | aTt | 35 | 35 | AY.103 | 0.000217 |
S | 51 | T51I | aCt | aTt | 35 | 35 | B.1 | 0.000321 |
S | 51 | T51I | aCt | aTt | 29 | 29 | AY.120.2 | 0.037275 |
S | 51 | T51I | aCt | aTt | 28 | 28 | B.1.351 | 0.000832 |
S | 51 | T51I | aCt | aTt | 27 | 27 | B.1.1 | 0.00049 |
S | 51 | T51I | aCt | aTt | 27 | 27 | B.1.1.70 | 0.009209 |
S | 51 | T51I | aCt | aTt | 24 | 24 | B.1.526 | 0.000564 |
S | 51 | T51I | aCt | aTt | 21 | 21 | B.1.177.61 | 0.913043 |
S | 51 | T51I | aCt | aTt | 14 | 14 | AY.102 | 0.000371 |
S | 51 | T51I | aCt | aTt | 14 | 14 | AY.46.3 | 0.013072 |
S | 51 | T51I | aCt | aTt | 14 | 14 | AY.6 | 0.000576 |
S | 51 | T51I | aCt | aTt | 14 | 14 | C.36.1 | 0.058091 |
S | 51 | T51I | aCt | aTt | 13 | 13 | B.1.499 | 0.013655 |
S | 51 | T51I | aCt | aTt | 12 | 12 | AY.25 | 0.000072 |
S | 51 | T51I | aCt | aTt | 12 | 12 | B.1.2 | 0.000106 |
S | 51 | T51I | aCt | aTt | 12 | 12 | B.1.525 | 0.001358 |
S | 51 | T51I | aCt | aTt | 11 | 11 | AY.5 | 0.000227 |
S | 51 | T51I | aCt | aTt | 11 | 11 | B.1.1.519 | 0.000437 |
S | 51 | T51I | aCt | aTt | 11 | 11 | B.1.177.21 | 0.000841 |
S | 51 | T51I | aCt | aTt | 10 | 10 | AY.3 | 0.000099 |
S | 51 | T51I | aCt | aTt | 10 | 10 | AY.42 | 0.000402 |
S | 51 | T51I | aCt | aTt | 9 | 9 | AY.46.5 | 0.001786 |
S | 51 | T51I | aCt | aTt | 9 | 9 | B.1.570 | 0.026471 |
S | 51 | T51I | aCt | aTt | 8 | 8 | B.1.429 | 0.000188 |
S | 51 | T51I | aCt | aTt | 7 | 7 | AY.119 | 0.000247 |
S | 51 | T51I | aCt | aTt | 7 | 7 | AY.13 | 0.001127 |
S | 51 | T51I | aCt | aTt | 7 | 7 | AY.39 | 0.000173 |
S | 51 | T51I | aCt | aTt | 6 | 6 | B.1.221 | 0.000426 |
S | 51 | T51I | aCt | aTt | 6 | 6 | C.16 | 0.006363 |
S | 51 | T51I | aCt | aTt | 5 | 5 | AY.116 | 0.001434 |
S | 51 | T51I | aCt | aTt | 5 | 5 | AY.20 | 0.000194 |
S | 51 | T51I | aCt | aTt | 5 | 5 | AY.29 | 0.000079 |
S | 51 | T51I | aCt | aTt | 5 | 5 | B.1.258 | 0.000333 |
S | 51 | T51I | aCT | aTC | 2 | 4 | 0.111111 | |
S | 51 | T51I | aCt | aTt | 2 | 4 | 0.111111 | |
S | 51 | T51I | aCt | aTt | 4 | 4 | AY.46 | 0.000416 |
S | 51 | T51I | aCt | aTt | 4 | 4 | B.1.637 | 0.000292 |
S | 51 | T51I | aCt | aTt | 4 | 4 | P.1 | 0.000063 |
S | 51 | T51I | aCt | aTt | 3 | 3 | AY.26 | 0.000085 |
S | 51 | T51I | aCt | aTt | 3 | 3 | AY.33 | 0.0002 |
S | 51 | T51I | aCt | aTt | 3 | 3 | AY.98.1 | 0.000145 |
S | 51 | T51I | aCt | aTt | 3 | 3 | B.1.160 | 0.000094 |
S | 51 | T51I | aCt | aTt | 3 | 3 | B.1.213 | 0.044776 |
S | 51 | T51I | aCt | aTt | 3 | 3 | B.1.427 | 0.000151 |
S | 51 | T51I | aCt | aTt | 3 | 3 | B.1.575 | 0.00091 |
S | 51 | T51I | aCt | aTt | 3 | 3 | B.1.596 | 0.000261 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AE.8 | 0.000978 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.117 | 0.000169 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.118 | 0.000125 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.14 | 0.000176 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.16.1 | 0.00094 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.4.2 | 0.000043 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.53 | 0.000575 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.59 | 0.001059 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.61 | 0.00021 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.68 | 0.000547 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.75 | 0.000112 |
S | 51 | T51I | aCt | aTt | 2 | 2 | AY.9.2 | 0.000073 |
S | 51 | T51I | aCt | aTt | 2 | 2 | B | 0.000256 |
S | 51 | T51I | aCt | aTt | 2 | 2 | B.1.1.28 | 0.000622 |
S | 51 | T51I | aCt | aTt | 2 | 2 | B.1.36 | 0.000292 |
S | 51 | T51I | aCt | aTt | 2 | 2 | B.1.36.16 | 0.002849 |
S | 51 | T51I | aCt | aTt | 2 | 2 | C.36 | 0.001821 |
S | 51 | T51I | aCt | aTt | 2 | 2 | P.1.7 | 0.000639 |
S | 51 | T51I | aCt | aTt | 1 | 1 | A.2.5 | 0.000499 |
S | 51 | T51I | aCt | aTt | 1 | 1 | A.23.1 | 0.000704 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AD.2 | 0.000219 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.107 | 0.000466 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.120.2.1 | 0.000498 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.23 | 0.00007 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.30 | 0.000396 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.35 | 0.000233 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.38 | 0.000499 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.39.1 | 0.00004 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.39.1.1 | 0.000725 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.40 | 0.000964 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.47 | 0.000031 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.54 | 0.000095 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.62 | 0.000436 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.63 | 0.000387 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.7 | 0.000196 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.70 | 0.000209 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.74 | 0.000116 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.9 | 0.000068 |
S | 51 | T51I | aCt | aTt | 1 | 1 | AY.99 | 0.001049 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.152 | 0.04 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.214 | 0.000055 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.25 | 0.000569 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.263 | 0.001558 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.284 | 0.000107 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.294 | 0.001266 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.317 | 0.000412 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.326 | 0.001761 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.1.434 | 0.000349 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.177.15 | 0.000631 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.177.4 | 0.000211 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.177.5 | 0.001242 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.177.6 | 0.000977 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.177.65 | 0.000665 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.177.73 | 0.000566 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.234 | 0.000132 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.240 | 0.000216 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.243 | 0.00007 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.260 | 0.003344 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.351.3 | 0.000876 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.362 | 0.001541 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.404 | 0.001302 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.524 | 0.001406 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.532 | 0.006211 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.617.1 | 0.000129 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.621 | 0.000089 |
S | 51 | T51I | aCt | aTt | 1 | 1 | B.1.630 | 0.005236 |
S | 51 | T51I | aCt | aTt | 1 | 1 | C.36.3 | 0.000567 |
S | 51 | T51I | aCt | aTt | 1 | 1 | C.37 | 0.000116 |
S | 51 | T51I | aCt | aTt | 1 | 1 | C.37.1 | 0.002618 |
S | 51 | T51I | aCt | aTt | 1 | 1 | D.2 | 0.000075 |
S | 51 | T51I | aCt | aTt | 1 | 1 | P.1.14 | 0.000048 |
S | 51 | T51I | aCt | aTt | 1 | 1 | Q.1 | 0.000126 |
S | 51 | T51I | aCt | aTt | 1 | 1 | Q.8 | 0.000165 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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