CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 477 | S477S | syn | agC | agT | 18490 | 18487 | 0.999838 | 22991-22993 | |
S | 477 | S477S | syn | AGc | TCc | 18490 | 3 | 0.00016225 | 22991-22993 |
Details of the mutation S477S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 477 | S477S | agC | agT | 18487 | 18490 | All | 0.003536 |
S | 477 | S477S | AGc | TCc | 3 | 18490 | All | 0.000001 |
S | 477 | S477S | agC | agT | 8110 | 8110 | B.1.617.2 | 0.030538 |
S | 477 | S477S | agC | agT | 5513 | 5513 | AY.43 | 0.024425 |
S | 477 | S477S | agC | agT | 514 | 514 | AY.39 | 0.012702 |
S | 477 | S477S | agC | agT | 431 | 431 | AY.4 | 0.000671 |
S | 477 | S477S | agC | agT | 427 | 427 | B.1.1.7 | 0.000382 |
S | 477 | S477S | agC | agT | 353 | 353 | AY.44 | 0.002149 |
S | 477 | S477S | agC | agT | 233 | 233 | AY.25 | 0.001401 |
S | 477 | S477S | agC | agT | 228 | 228 | AY.102 | 0.006045 |
S | 477 | S477S | agC | agT | 125 | 125 | AY.103 | 0.000776 |
S | 477 | S477S | agC | agT | 125 | 125 | AY.119 | 0.004414 |
S | 477 | S477S | agC | agT | 121 | 121 | B.1.541 | 0.535398 |
S | 477 | S477S | agC | agT | 116 | 116 | AY.72 | 0.157823 |
S | 477 | S477S | agC | agT | 114 | 114 | B.1.1.429 | 0.525346 |
S | 477 | S477S | agC | agT | 106 | 106 | B.1.2 | 0.000933 |
S | 477 | S477S | agC | agT | 104 | 104 | AY.12 | 0.03287 |
S | 477 | S477S | agC | agT | 85 | 85 | B.1.1 | 0.001542 |
S | 477 | S477S | agC | agT | 83 | 83 | AY.46 | 0.008639 |
S | 477 | S477S | agC | agT | 79 | 79 | AY.20 | 0.00307 |
S | 477 | S477S | agC | agT | 69 | 69 | AY.3 | 0.000686 |
S | 477 | S477S | agC | agT | 65 | 65 | AY.42 | 0.002615 |
S | 477 | S477S | agC | agT | 62 | 62 | AY.5.3 | 0.020918 |
S | 477 | S477S | agC | agT | 51 | 51 | AY.32 | 0.027157 |
S | 477 | S477S | agC | agT | 47 | 47 | AY.116 | 0.013479 |
S | 477 | S477S | agC | agT | 46 | 46 | AY.33 | 0.003072 |
S | 477 | S477S | agC | agT | 45 | 45 | AY.120 | 0.001673 |
S | 477 | S477S | agC | agT | 42 | 42 | B.1.429 | 0.000988 |
S | 477 | S477S | agC | agT | 41 | 41 | AY.5.4 | 0.011345 |
S | 477 | S477S | agC | agT | 40 | 40 | AY.120.1 | 0.012841 |
S | 477 | S477S | agC | agT | 38 | 38 | AY.98 | 0.003002 |
S | 477 | S477S | agC | agT | 37 | 37 | AY.111 | 0.006777 |
S | 477 | S477S | agC | agT | 36 | 36 | AY.46.6 | 0.002599 |
S | 477 | S477S | agC | agT | 32 | 32 | AY.23 | 0.002232 |
S | 477 | S477S | agC | agT | 27 | 30 | P.1 | 0.000425 |
S | 477 | S477S | AGc | TCc | 3 | 30 | P.1 | 0.000047 |
S | 477 | S477S | agC | agT | 28 | 28 | AY.100 | 0.001288 |
S | 477 | S477S | agC | agT | 28 | 28 | B.1.625 | 0.065882 |
S | 477 | S477S | agC | agT | 24 | 24 | AY.5 | 0.000496 |
S | 477 | S477S | agC | agT | 22 | 22 | AY.117 | 0.001859 |
S | 477 | S477S | agC | agT | 22 | 22 | AY.47 | 0.000684 |
S | 477 | S477S | agC | agT | 22 | 22 | B.1.177 | 0.00029 |
S | 477 | S477S | agC | agT | 21 | 21 | AY.106 | 0.007033 |
S | 477 | S477S | agC | agT | 21 | 21 | B.1 | 0.000192 |
S | 477 | S477S | agC | agT | 20 | 20 | P.2 | 0.003733 |
S | 477 | S477S | agC | agT | 19 | 19 | AY.118 | 0.00119 |
S | 477 | S477S | agC | agT | 19 | 19 | C.37 | 0.002205 |
S | 477 | S477S | agC | agT | 18 | 18 | AY.84 | 0.007874 |
S | 477 | S477S | agC | agT | 17 | 17 | AY.41 | 0.004997 |
S | 477 | S477S | agC | agT | 17 | 17 | AY.92 | 0.004884 |
S | 477 | S477S | agC | agT | 15 | 15 | AY.121 | 0.00203 |
S | 477 | S477S | agC | agT | 15 | 15 | AY.45 | 0.001825 |
S | 477 | S477S | agC | agT | 15 | 15 | AY.77 | 0.016911 |
S | 477 | S477S | agC | agT | 15 | 15 | B.1.177.86 | 0.002752 |
S | 477 | S477S | agC | agT | 14 | 14 | AY.113 | 0.001993 |
S | 477 | S477S | agC | agT | 14 | 14 | AY.74 | 0.001619 |
S | 477 | S477S | agC | agT | 13 | 13 | B.1.427 | 0.000656 |
S | 477 | S477S | agC | agT | 12 | 12 | AY.26 | 0.00034 |
S | 477 | S477S | agC | agT | 11 | 11 | AY.46.1 | 0.011294 |
S | 477 | S477S | agC | agT | 11 | 11 | AY.75 | 0.000616 |
S | 477 | S477S | agC | agT | 11 | 11 | AY.99 | 0.011542 |
S | 477 | S477S | agC | agT | 11 | 11 | B.1.1.214 | 0.00061 |
S | 477 | S477S | agC | agT | 10 | 10 | AY.48 | 0.004651 |
S | 477 | S477S | agC | agT | 10 | 10 | AY.59 | 0.005297 |
S | 477 | S477S | agC | agT | 10 | 10 | AY.9.2 | 0.000367 |
S | 477 | S477S | agC | agT | 10 | 10 | M.1 | 0.232558 |
S | 477 | S477S | agC | agT | 9 | 9 | AY.34.1 | 0.004589 |
S | 477 | S477S | agC | agT | 9 | 9 | B.1.210 | 0.01919 |
S | 477 | S477S | agC | agT | 9 | 9 | B.1.351 | 0.000268 |
S | 477 | S477S | agC | agT | 8 | 8 | AY.27 | 0.000518 |
S | 477 | S477S | agC | agT | 8 | 8 | AY.29 | 0.000126 |
S | 477 | S477S | agC | agT | 8 | 8 | AY.36 | 0.001186 |
S | 477 | S477S | agC | agT | 8 | 8 | AY.4.2 | 0.000174 |
S | 477 | S477S | agC | agT | 8 | 8 | AY.64 | 0.004762 |
S | 477 | S477S | agC | agT | 8 | 8 | AY.98.1 | 0.000387 |
S | 477 | S477S | agC | agT | 8 | 8 | B.1.221 | 0.000568 |
S | 477 | S477S | agC | agT | 8 | 8 | C.35 | 0.006192 |
S | 477 | S477S | agC | agT | 7 | 7 | AY.114 | 0.001618 |
S | 477 | S477S | agC | agT | 7 | 7 | AY.39.1 | 0.000277 |
S | 477 | S477S | agC | agT | 7 | 7 | AY.6 | 0.000288 |
S | 477 | S477S | agC | agT | 7 | 7 | AY.95 | 0.005327 |
S | 477 | S477S | agC | agT | 7 | 7 | B.1.258 | 0.000466 |
S | 477 | S477S | agC | agT | 6 | 6 | AY.3.1 | 0.000512 |
S | 477 | S477S | agC | agT | 6 | 6 | AY.55 | 0.005505 |
S | 477 | S477S | agC | agT | 6 | 6 | AY.67 | 0.002786 |
S | 477 | S477S | agC | agT | 6 | 6 | B.1.517 | 0.002562 |
S | 477 | S477S | agC | agT | 6 | 6 | P.1.7 | 0.001916 |
S | 477 | S477S | agC | agT | 5 | 5 | A.27 | 0.008278 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.10 | 0.00265 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.107 | 0.00233 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.23.1 | 0.002087 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.4.3 | 0.004209 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.46.2 | 0.003177 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.58 | 0.004537 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.75.1 | 0.000902 |
S | 477 | S477S | agC | agT | 5 | 5 | AY.89 | 0.02451 |
S | 477 | S477S | agC | agT | 5 | 5 | B | 0.000639 |
S | 477 | S477S | agC | agT | 5 | 5 | B.1.1.28 | 0.001556 |
S | 477 | S477S | agC | agT | 5 | 5 | B.1.234 | 0.00066 |
S | 477 | S477S | agC | agT | 5 | 5 | B.1.526 | 0.000118 |
S | 477 | S477S | agC | agT | 5 | 5 | B.1.629 | 0.066667 |
S | 477 | S477S | agC | agT | 5 | 5 | B.1.637 | 0.000365 |
S | 477 | S477S | agC | agT | 5 | 5 | Q.3 | 0.000725 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.110 | 0.000451 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.35 | 0.000932 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.53 | 0.00115 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.61 | 0.000419 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.68 | 0.001095 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.86 | 0.00332 |
S | 477 | S477S | agC | agT | 4 | 4 | AY.9.1 | 0.000335 |
S | 477 | S477S | agC | agT | 4 | 4 | B.1.1.354 | 0.017544 |
S | 477 | S477S | agC | agT | 4 | 4 | B.1.1.434 | 0.001394 |
S | 477 | S477S | agC | agT | 4 | 4 | B.1.177.23 | 0.012945 |
S | 477 | S477S | agC | agT | 4 | 4 | P.1.10 | 0.001078 |
S | 477 | S477S | agC | agT | 3 | 3 | AY.108 | 0.003308 |
S | 477 | S477S | agC | agT | 3 | 3 | AY.14 | 0.000264 |
S | 477 | S477S | agC | agT | 3 | 3 | AY.29.1 | 0.000662 |
S | 477 | S477S | agC | agT | 3 | 3 | AY.52 | 0.002443 |
S | 477 | S477S | agC | agT | 3 | 3 | AY.87 | 0.002498 |
S | 477 | S477S | agC | agT | 3 | 3 | AY.91 | 0.002191 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.1.255 | 0.009091 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.1.294 | 0.003797 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.1.63 | 0.001157 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.177.88 | 0.037037 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.258.14 | 0.002941 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.466.2 | 0.001174 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.525 | 0.000339 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.596 | 0.000261 |
S | 477 | S477S | agC | agT | 3 | 3 | B.1.609 | 0.001438 |
S | 477 | S477S | agC | agT | 2 | 2 | 0.111111 | |
S | 477 | S477S | agC | agT | 2 | 2 | A.2.5 | 0.000998 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.1 | 0.000791 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.105 | 0.001286 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.109 | 0.001479 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.11 | 0.002677 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.19 | 0.002281 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.21 | 0.003795 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.46.4 | 0.000329 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.54 | 0.000191 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.56 | 0.00321 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.73 | 0.001331 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.93 | 0.000546 |
S | 477 | S477S | agC | agT | 2 | 2 | AY.94 | 0.000885 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.1.1 | 0.000653 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.1.269 | 0.002706 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.1.300 | 0.021505 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.1.311 | 0.000716 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.1.369 | 0.000892 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.1.500 | 0.04 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.166 | 0.016949 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.177.44 | 0.001038 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.177.65 | 0.001331 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.243 | 0.000139 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.36 | 0.000292 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.560 | 0.009259 |
S | 477 | S477S | agC | agT | 2 | 2 | B.1.575.1 | 0.004878 |
S | 477 | S477S | agC | agT | 2 | 2 | P.3 | 0.00319 |
S | 477 | S477S | agC | agT | 2 | 2 | Q.4 | 0.00091 |
S | 477 | S477S | agC | agT | 2 | 2 | S.1 | 0.009901 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.104 | 0.001984 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.2 | 0.000356 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.30 | 0.000396 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.34 | 0.000097 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.37 | 0.000316 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.38 | 0.000499 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.4.4 | 0.000409 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.4.5 | 0.000107 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.51 | 0.000909 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.60 | 0.000938 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.62 | 0.000436 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.65 | 0.000533 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.7.1 | 0.000113 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.76 | 0.004831 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.79 | 0.001211 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.85 | 0.000427 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.9 | 0.000068 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.90 | 0.000684 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.91.1 | 0.004065 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.96 | 0.002075 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.97 | 0.001701 |
S | 477 | S477S | agC | agT | 1 | 1 | AY.99.2 | 0.000092 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.121 | 0.002427 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.161 | 0.003534 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.197 | 0.037037 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.237 | 0.005405 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.284 | 0.000107 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.303 | 0.002762 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.306 | 0.000438 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.316 | 0.000925 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.317 | 0.000412 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.376 | 0.005952 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.409 | 0.002833 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.519 | 0.00004 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.61 | 0.008772 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.1.70 | 0.000341 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.177.35 | 0.000691 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.177.75 | 0.001041 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.222 | 0.001692 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.240 | 0.000216 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.256 | 0.017241 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.289 | 0.00266 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.332 | 0.003497 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.340 | 0.004292 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.357 | 0.009524 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.36.29 | 0.000517 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.378 | 0.006849 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.426 | 0.001009 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.496 | 0.125 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.540 | 0.009709 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.568 | 0.001111 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.575.2 | 0.004808 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.595 | 0.000261 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.617.1 | 0.000129 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.619.1 | 0.000641 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.627 | 0.00202 |
S | 477 | S477S | agC | agT | 1 | 1 | B.1.8 | 0.001972 |
S | 477 | S477S | agC | agT | 1 | 1 | C.37.1 | 0.002618 |
S | 477 | S477S | agC | agT | 1 | 1 | P.1.12 | 0.000484 |
S | 477 | S477S | agC | agT | 1 | 1 | P.1.6 | 0.001946 |
S | 477 | S477S | agC | agT | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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