CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = P681R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S681P681RnonsyncCtcGt276292027625600.9998723603-23605
S681P681RnonsyncCTcGC27629203040.00011002923603-23605
S681P681RnonsyncCTcGG2762920310.0000112223603-23605
S681P681RnonsyncCTcGA2762920250.000009048423603-23605

Details of the mutation P681R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S681P681RcCtcGt27625602762920All0.528372
S681P681RcCTcGC3042762920All0.000058
S681P681RcCTcGG312762920All0.000006
S681P681RcCTcGA252762920All0.000005
S681P681RcCtcGt641813641875AY.40.998932
S681P681RcCTcGC62641875AY.40.000096
S681P681RcCtcGt264157264167B.1.617.20.994661
S681P681RcCTcGC10264167B.1.617.20.000038
S681P681RcCtcGt224371224371AY.430.994068
S681P681RcCtcGt165836165844AY.250.997474
S681P681RcCTcGC7165844AY.250.000042
S681P681RcCTcGA1165844AY.250.000006
S681P681RcCtcGt163492163539AY.440.995137
S681P681RcCTcGC44163539AY.440.000268
S681P681RcCTcGG2163539AY.440.000012
S681P681RcCTcGA1163539AY.440.000006
S681P681RcCtcGt160438160443AY.1030.996169
S681P681RcCTcGC5160443AY.1030.000031
S681P681RcCtcGt100253100318AY.30.997155
S681P681RcCTcGG24100318AY.30.000239
S681P681RcCTcGC22100318AY.30.000219
S681P681RcCTcGA19100318AY.30.000189
S681P681RcCtcGt6333663336AY.290.999038
S681P681RcCtcGt4834648348AY.50.998307
S681P681RcCTcGC248348AY.50.000041
S681P681RcCtcGt4607946079AY.4.20.999393
S681P681RcCtcGt4019840198AY.390.993353
S681P681RcCtcGt3762237626AY.1020.997508
S681P681RcCTcGC437626AY.1020.000106
S681P681RcCtcGt3520535212AY.260.996659
S681P681RcCTcGC735212AY.260.000198
S681P681RcCtcGt3193232054AY.470.99325
S681P681RcCTcGC12232054AY.470.003795
S681P681RcCtcGt2822928229AY.1190.996716
S681P681RcCtcGt2710327105AY.9.20.995482
S681P681RcCTcGG127105AY.9.20.000037
S681P681RcCTcGC127105AY.9.20.000037
S681P681RcCtcGt2685726857AY.1200.998513
S681P681RcCtcGt2566025661AY.200.997279
S681P681RcCTcGC125661AY.200.000039
S681P681RcCtcGt2514425144AY.39.10.996039
S681P681RcCtcGt2476424764AY.420.996259
S681P681RcCtcGt2428924289AY.60.998972
S681P681RcCtcGt2166121661AY.1000.99655
S681P681RcCtcGt2058220583AY.98.10.996804
S681P681RcCTcGC120583AY.98.10.000048
S681P681RcCtcGt1778917790AY.750.996583
S681P681RcCTcGC117790AY.750.000056
S681P681RcCtcGt1591515915AY.1180.997056
S681P681RcCtcGt1544115441AY.270.999353
S681P681RcCtcGt1485514855AY.330.991987
S681P681RcCtcGt1478314783AY.90.999256
S681P681RcCtcGt1427714277AY.230.995815
S681P681RcCtcGt1377313773AY.46.60.994512
S681P681RcCtcGt1258612587AY.980.994233
S681P681RcCTcGC112587AY.980.000079
S681P681RcCtcGt1189611896AY.9.10.995981
S681P681RcCtcGt1179111792AY.1170.996535
S681P681RcCTcGG111792AY.1170.000085
S681P681RcCtcGt1170311703AY.3.10.997783
S681P681RcCtcGt1134511345AY.140.998504
S681P681RcCtcGt1073210732AY.99.20.989033
S681P681RcCtcGt1045710457AY.540.997044
S681P681RcCtcGt1028310283AY.340.997091
S681P681RcCtcGt94409440AY.610.989103
S681P681RcCtcGt93559356AY.460.973668
S681P681RcCTcGC19356AY.460.000104
S681P681RcCtcGt89538953AY.4.50.962378
S681P681RcCtcGt88568856AY.7.10.998084
S681P681RcCtcGt88468846AY.1100.996845
S681P681RcCtcGt86328632AY.740.998265
S681P681RcCtcGt80608060AY.450.980774
S681P681RcCtcGt76637664B.1.617.10.988264
S681P681RcCTcGA17664B.1.617.10.000129
S681P681RcCtcGt73527358AY.1210.994858
S681P681RcCTcGC67358AY.1210.000812
S681P681RcCtcGt69856985AY.1130.994589
S681P681RcCtcGt66956695AY.4.2.10.997467
S681P681RcCtcGt66616661AY.360.987254
S681P681RcCtcGt62076207AY.130.999195
S681P681RcCtcGt60746074AY.46.40.999177
S681P681RcCtcGt54835483AY.75.10.98864
S681P681RcCtcGt54475447AY.1110.997619
S681P681RcCtcGt53455345AY.690.99776
S681P681RcCtcGt51005100AY.70.999608
S681P681RcCtcGt50295034AY.46.50.997817
S681P681RcCTcGC55034AY.46.50.000992
S681P681RcCtcGt47824783AY.700.997081
S681P681RcCTcGC14783AY.700.000209
S681P681RcCtcGt45344534AY.29.10.999779
S681P681RcCtcGt43164316AY.1140.997458
S681P681RcCtcGt42824282AY.350.997903
S681P681RcCtcGt36513651AY.930.996996
S681P681RcCtcGt36013601AY.5.40.996403
S681P681RcCtcGt35743574AY.680.978374
S681P681RcCtcGt34683468AY.530.997125
S681P681RcCtcGt34583458AY.920.993393
S681P681RcCtcGt34543454AY.1160.990536
S681P681RcCtcGt33543354AY.410.985891
S681P681RcCtcGt32053206AY.116.10.998131
S681P681RcCTcGG13206AY.116.10.000311
S681P681RcCtcGt31523152AY.370.996207
S681P681RcCtcGt31393139AY.120.992099
S681P681RcCtcGt31063106AY.120.10.997111
S681P681RcCtcGt29622962AY.1060.991962
S681P681RcCtcGt29482948AY.5.30.994602
S681P681RcCtcGt27982798AY.20.996439
S681P681RcCtcGt25852585AY.160.981397
S681P681RcCtcGt25852585AY.631
S681P681RcCtcGt25212521AY.300.997626
S681P681RcCtcGt25162516AY.10.995647
S681P681RcCtcGt24202420AY.4.40.99018
S681P681RcCtcGt23962396AY.23.11
S681P681RcCtcGt23292329AY.850.994874
S681P681RcCtcGt23192319B.1.466.20.907277
S681P681RcCtcGt22982298AY.240.990517
S681P681RcCtcGt22882288AY.620.99695
S681P681RcCtcGt22692270AY.840.992563
S681P681RcCTcGA12270AY.840.000437
S681P681RcCtcGt22532253AY.940.997344
S681P681RcCtcGt21502151AY.670.998143
S681P681RcCTcGA12151AY.670.000464
S681P681RcCtcGt21472147AY.480.998605
S681P681RcCtcGt21342134AY.1070.994408
S681P681RcCtcGt21042104Q.40.956799
S681P681RcCtcGt21012101AY.16.10.987312
S681P681RcCtcGt20942094AY.710.994774
S681P681RcCtcGt20292029AY.1010.995096
S681P681RcCtcGt20032003AY.120.2.10.998007
S681P681RcCtcGt19731973AY.380.985022
S681P681RcCtcGt19151915B.10.01754
S681P681RcCtcGt18981898AY.34.10.967874
S681P681RcCtcGt18831883AY.100.99788
S681P681RcCtcGt18741874AY.320.99787
S681P681RcCtcGt18741874AY.590.992585
S681P681RcCtcGt18681868AY.650.995736
S681P681RcCtcGt17821782AY.7.20.996644
S681P681RcCtcGt16751675AY.640.997024
S681P681RcCtcGt16501650AY.81
S681P681RcCtcGt15631563AY.46.20.993011
S681P681RcCtcGt15471547AY.1050.994855
S681P681RcCtcGt15201520AY.570.997375
S681P681RcCtcGt15001500AY.730.998004
S681P681RcCtcGt14611461AY.901
S681P681RcCtcGt14001400A.23.10.985915
S681P681RcCtcGt13781378AY.39.1.10.998551
S681P681RcCtcGt13531353AY.4.10.997788
S681P681RcCtcGt13361336AY.910.975895
S681P681RcCtcGt13351335AY.1090.987426
S681P681RcCtcGt12471247AY.500.996803
S681P681RcCtcGt12361236AY.950.940639
S681P681RcCtcGt12241224AY.520.996743
S681P681RcCtcGt12031203AY.860.99834
S681P681RcCtcGt11951195AY.870.995004
S681P681RcCtcGt11821182AY.4.30.994949
S681P681RcCtcGt11241125AY.880.993811
S681P681RcCTcGA11125AY.880.000884
S681P681RcCtcGt11001100AY.511
S681P681RcCtcGt10881088AY.580.987296
S681P681RcCtcGt10821082AY.550.992661
S681P681RcCtcGt10611061AY.600.99531
S681P681RcCtcGt10531053AY.46.30.983193
S681P681RcCtcGt10361036AY.400.999036
S681P681RcCtcGt971971AY.46.10.99692
S681P681RcCtcGt938938AY.990.98426
S681P681RcCtcGt935935AY.661
S681P681RcCtcGt899899AY.1080.99118
S681P681RcCtcGt887887AY.771
S681P681RcCtcGt886886AY.801
S681P681RcCtcGt869869AY.190.990878
S681P681RcCtcGt823823AY.790.996368
S681P681RcCtcGt771771B.1.5510.994839
S681P681RcCtcGt762762AY.120.20.979434
S681P681RcCtcGt747747AY.111
S681P681RcCtcGt735735AY.721
S681P681RcCtcGt734734AY.820.995929
S681P681RcCtcGt649649AY.39.21
S681P681RcCtcGt647647AY.780.996918
S681P681RcCtcGt640640AY.99.10.993789
S681P681RcCtcGt620620AY.560.995185
S681P681RcCtcGt586586AY.970.996599
S681P681RcCtcGt578578AY.830.996552
S681P681RcCtcGt524524AY.210.994307
S681P681RcCtcGt513513AY.280.969754
S681P681RcCtcGt506506AY.9.2.11
S681P681RcCtcGt501501AY.810.998008
S681P681RcCtcGt498498AY.1040.988095
S681P681RcCtcGt477477AY.220.997908
S681P681RcCtcGt473473AU.30.99789
S681P681RcCtcGt449449AY.150.997778
S681P681RcCtcGt412412AU.20.997579
S681P681RcCtcGt406406AY.5.21
S681P681RcCtcGt399399AY.960.827801
S681P681RcCtcGt334334B.1.617.30.997015
S681P681RcCtcGt311311AY.490.99361
S681P681RcCtcGt305305B.1.1.250.173394
S681P681RcCtcGt265265AY.5.10.996241
S681P681RcCtcGt245245AY.91.10.995935
S681P681RcCtcGt223223B0.028502
S681P681RcCtcGt209209P.1.81
S681P681RcCtcGt207207AY.761
S681P681RcCtcGt204204AY.891
S681P681RcCtcGt189189B.1.1.70.000169
S681P681RcCtcGt184184AY.1150.958333
S681P681RcCtcGt148150C.360.134791
S681P681RcCTcGG2150C.360.001821
S681P681RcCtcGt136136B.1.1.5280.653846
S681P681RcCtcGt123123B.1.10.002231
S681P681RcCtcGt120120AY.170.983607
S681P681RcCtcGt9999AY.181
S681P681RcCtcGt9999B.1.1.5260.351064
S681P681RcCtcGt9898P.1.111
S681P681RcCtcGt6767B.1.1.500.045485
S681P681RcCtcGt6363B.1.5960.00549
S681P681RcCtcGt5757B.1.1.3340.934426
S681P681RcCtcGt5555P.10.000866
S681P681RcCtcGt5454AY.311
S681P681RcCtcGt5454B.1.6040.931034
S681P681RcCtcGt4747B.1.3510.001397
S681P681RcCtcGt4242B.1.1.1410.084507
S681P681RcCtcGt4242B.1.4620.304348
S681P681RcCtcGt3939B.1.36.220.047101
S681P681RcCtcGt3737B.1.36.80.037
S681P681RcCtcGt3535A0.013545
S681P681RcCtcGt3535Q.80.005772
S681P681RcCtcGt3131B.1.5760.028105
S681P681RcCtcGt2626B.1.20.000229
S681P681RcCtcGt2222B.1.1770.00029
S681P681RcCtcGt2222B.1.6230.011803
S681P681RcCtcGt2020C.370.002321
S681P681RcCtcGt1818B.1.4740.034221
S681P681RcCtcGt1717B.1.6330.708333
S681P681RcCtcGt1616B.1.6210.001416
S681P681RcCtcGt1414B.1.2430.000974
S681P681RcCtcGt99B.1.1.2160.008014
S681P681RcCtcGt99B.1.5260.000212
S681P681RcCtcGt99B.1.6320.060403
S681P681RcCtcGt88B.1.1.10.002614
S681P681RcCtcGt88C.140.034632
S681P681RcCtcGt77B.1.2580.000466
S681P681RcCtcGt77P.1.70.002235
S681P681RcCtcGt66B.1.1.2940.007595
S681P681RcCtcGt66B.1.1.340.078947
S681P681RcCtcGt66B.1.2140.021978
S681P681RcCtcGt66B.1.360.000875
S681P681RcCtcGt66B.1.36.310.010508
S681P681RcCtcGt66B.1.4690.021661
S681P681RcCtcGt66B.1.6280.002114
S681P681RcCtcGt55B.1.1.3060.002192
S681P681RcCtcGt55B.1.1.3170.002058
S681P681RcCtcGt55B.1.177.860.000917
S681P681RcCtcGt55B.1.36.10.005701
S681P681RcCtcGt55B.1.3690.001426
S681P681RcCtcGt55B.1.3750.004098
S681P681RcCtcGt55B.1.4590.020408
S681P681RcCtcGt44B.1.1.3110.001433
S681P681RcCtcGt44B.1.1.5190.000159
S681P681RcCtcGt44B.1.1.5230.00625
S681P681RcCtcGt44B.1.1.530.054795
S681P681RcCtcGt44B.1.1570.01194
S681P681RcCtcGt44B.1.1920.037037
S681P681RcCtcGt44B.1.6290.053333
S681P681RcCtcGt44B.1.6370.000292
S681P681RcCtcGt330.166667
S681P681RcCtcGt33B.1.1.3550.046154
S681P681RcCtcGt33B.1.1.4200.003018
S681P681RcCtcGt33B.1.2470.044776
S681P681RcCtcGt33B.1.3350.030928
S681P681RcCtcGt33B.1.36.290.001552
S681P681RcCtcGt33B.1.6000.017544
S681P681RcCtcGt33B.1.6180.012097
S681P681RcCtcGt22A.10.000564
S681P681RcCtcGt22B.1.1.4090.005666
S681P681RcCtcGt22B.1.1.5120.057143
S681P681RcCtcGt22B.1.1600.000062
S681P681RcCtcGt22B.1.258.30.00335
S681P681RcCtcGt22B.1.3010.011834
S681P681RcCtcGt22B.1.3230.041667
S681P681RcCtcGt22B.1.351.30.001753
S681P681RcCtcGt22B.1.36.170.000988
S681P681RcCtcGt22B.1.3670.001585
S681P681RcCtcGt22B.1.3800.013245
S681P681RcCtcGt22B.1.415.10.015152
S681P681RcCtcGt22B.1.4270.000101
S681P681RcCtcGt22B.1.4410.019231
S681P681RcCtcGt22B.1.5300.014286
S681P681RcCtcGt22B.1.5640.000852
S681P681RcCtcGt22B.1.5820.000981
S681P681RcCtcGt22B.1.6090.000959
S681P681RcCtcGt22B.1.6190.001742
S681P681RcCtcGt22B.60.00182
S681P681RcCtcGt22C.180.005181
S681P681RcCtcGt22C.330.117647
S681P681RcCtcGt22C.36.3.10.005435
S681P681RcCtcGt22C.37.10.005236
S681P681RcCtcGt22L.30.007092
S681P681RcCtcGt22P.1.10.000635
S681P681RcCtcGt22P.1.130.001797
S681P681RcCtcGt22P.1.160.000748
S681P681RcCtcGt22P.1.170.000324
S681P681RcCtcGt22P.1.17.10.00175
S681P681RcCtcGt11B.1.1.1170.009709
S681P681RcCtcGt11B.1.1.1210.002427
S681P681RcCtcGt11B.1.1.2200.001859
S681P681RcCtcGt11B.1.1.2310.003096
S681P681RcCtcGt11B.1.1.2690.001353
S681P681RcCtcGt11B.1.1.280.000311
S681P681RcCtcGt11B.1.1.2980.000862
S681P681RcCtcGt11B.1.1.3010.001179
S681P681RcCtcGt11B.1.1.3120.001912
S681P681RcCtcGt11B.1.1.3180.000302
S681P681RcCtcGt11B.1.1.330.000421
S681P681RcCtcGt11B.1.1.390.00051
S681P681RcCtcGt11B.1.1.4040.015873
S681P681RcCtcGt11B.1.1.4640.001473
S681P681RcCtcGt11B.1.1.510.001718
S681P681RcCtcGt11B.1.1260.001276
S681P681RcCtcGt11B.1.1310.008772
S681P681RcCtcGt11B.1.177.730.000566
S681P681RcCtcGt11B.1.2060.000816
S681P681RcCtcGt11B.1.2210.000071
S681P681RcCtcGt11B.1.2220.001692
S681P681RcCtcGt11B.1.258.110.000396
S681P681RcCtcGt11B.1.258.120.007874
S681P681RcCtcGt11B.1.3550.011111
S681P681RcCtcGt11B.1.3660.004878
S681P681RcCTcGC11B.1.3770.004566
S681P681RcCtcGt11B.1.3930.028571
S681P681RcCtcGt11B.1.3960.000706
S681P681RcCtcGt11B.1.4000.000429
S681P681RcCtcGt11B.1.4320.011236
S681P681RcCtcGt11B.1.4330.003195
S681P681RcCtcGt11B.1.4600.017857
S681P681RcCtcGt11B.1.4850.014925
S681P681RcCtcGt11B.1.5250.000113
S681P681RcCtcGt11B.1.5270.003704
S681P681RcCtcGt11B.1.5330.009615
S681P681RcCtcGt11B.1.5600.00463
S681P681RcCtcGt11B.1.5800.004065
S681P681RcCtcGt11B.1.5990.00365
S681P681RcCtcGt11B.1.619.10.000641
S681P681RcCtcGt11B.1.6310.003367
S681P681RcCtcGt11B.550.00295
S681P681RcCtcGt11C.170.055556
S681P681RcCtcGt11C.36.30.000567
S681P681RcCtcGt11P.1.150.000232
S681P681RcCtcGt11P.20.000187
S681P681RcCtcGt11P.50.013699

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.