CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 25 | P25P | syn | ccC | ccT | 11603 | 11457 | 0.987417 | 21635-21637 | |
S | 25 | P25P | syn | ccC | ccA | 11603 | 101 | 0.00870465 | 21635-21637 | |
S | 25 | P25P | syn | ccC | ccG | 11603 | 45 | 0.00387831 | 21635-21637 |
Details of the mutation P25P within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 25 | P25P | ccC | ccT | 11457 | 11603 | All | 0.002191 |
S | 25 | P25P | ccC | ccA | 101 | 11603 | All | 0.000019 |
S | 25 | P25P | ccC | ccG | 45 | 11603 | All | 0.000009 |
S | 25 | P25P | ccC | ccT | 5048 | 5049 | B.1.1.37 | 0.973578 |
S | 25 | P25P | ccC | ccG | 1 | 5049 | B.1.1.37 | 0.000193 |
S | 25 | P25P | ccC | ccT | 1558 | 1558 | B.1.619.1 | 0.999359 |
S | 25 | P25P | ccC | ccT | 1101 | 1101 | B.1.619 | 0.959059 |
S | 25 | P25P | ccC | ccT | 600 | 631 | B.1.1.7 | 0.000537 |
S | 25 | P25P | ccC | ccA | 30 | 631 | B.1.1.7 | 0.000027 |
S | 25 | P25P | ccC | ccG | 1 | 631 | B.1.1.7 | 0.000001 |
S | 25 | P25P | ccC | ccT | 380 | 380 | AY.54 | 0.036232 |
S | 25 | P25P | ccC | ccT | 343 | 344 | AY.103 | 0.00213 |
S | 25 | P25P | ccC | ccA | 1 | 344 | AY.103 | 0.000006 |
S | 25 | P25P | ccC | ccT | 216 | 253 | AY.4 | 0.000336 |
S | 25 | P25P | ccC | ccA | 36 | 253 | AY.4 | 0.000056 |
S | 25 | P25P | ccC | ccG | 1 | 253 | AY.4 | 0.000002 |
S | 25 | P25P | ccC | ccT | 185 | 198 | B.1.617.2 | 0.000697 |
S | 25 | P25P | ccC | ccA | 7 | 198 | B.1.617.2 | 0.000026 |
S | 25 | P25P | ccC | ccG | 6 | 198 | B.1.617.2 | 0.000023 |
S | 25 | P25P | ccC | ccT | 185 | 185 | B.1.630 | 0.968586 |
S | 25 | P25P | ccC | ccT | 148 | 148 | B.1.526 | 0.003479 |
S | 25 | P25P | ccC | ccT | 126 | 126 | B.1.2 | 0.001109 |
S | 25 | P25P | ccC | ccT | 98 | 98 | AY.25 | 0.000589 |
S | 25 | P25P | ccC | ccT | 87 | 92 | B.1 | 0.000797 |
S | 25 | P25P | ccC | ccA | 3 | 92 | B.1 | 0.000027 |
S | 25 | P25P | ccC | ccG | 2 | 92 | B.1 | 0.000018 |
S | 25 | P25P | ccC | ccT | 80 | 80 | AY.4.2 | 0.001735 |
S | 25 | P25P | ccC | ccT | 73 | 73 | B.1.177.80 | 0.139579 |
S | 25 | P25P | ccC | ccT | 66 | 68 | AY.44 | 0.000402 |
S | 25 | P25P | ccC | ccA | 2 | 68 | AY.44 | 0.000012 |
S | 25 | P25P | ccC | ccT | 61 | 61 | AY.100 | 0.002806 |
S | 25 | P25P | ccC | ccT | 59 | 59 | B.1.1.222 | 0.012036 |
S | 25 | P25P | ccC | ccT | 57 | 57 | P.1 | 0.000898 |
S | 25 | P25P | ccC | ccT | 52 | 52 | AY.47 | 0.001617 |
S | 25 | P25P | ccC | ccT | 49 | 49 | AY.39 | 0.001211 |
S | 25 | P25P | ccC | ccT | 45 | 47 | AY.43 | 0.000199 |
S | 25 | P25P | ccC | ccA | 2 | 47 | AY.43 | 0.000009 |
S | 25 | P25P | ccC | ccT | 44 | 45 | B.1.1.519 | 0.001747 |
S | 25 | P25P | ccC | ccA | 1 | 45 | B.1.1.519 | 0.00004 |
S | 25 | P25P | ccC | ccT | 39 | 40 | AY.3 | 0.000388 |
S | 25 | P25P | ccC | ccA | 1 | 40 | AY.3 | 0.00001 |
S | 25 | P25P | ccC | ccT | 35 | 35 | AY.26 | 0.000991 |
S | 25 | P25P | ccC | ccT | 33 | 33 | AY.99.2 | 0.003041 |
S | 25 | P25P | ccC | ccG | 29 | 29 | B.1.1.28 | 0.009026 |
S | 25 | P25P | ccC | ccT | 28 | 28 | AY.121 | 0.003789 |
S | 25 | P25P | ccC | ccT | 22 | 22 | B.1.1 | 0.000399 |
S | 25 | P25P | ccC | ccT | 22 | 22 | B.1.177.81 | 0.004165 |
S | 25 | P25P | ccC | ccT | 21 | 21 | AY.20 | 0.000816 |
S | 25 | P25P | ccC | ccT | 18 | 20 | B.1.177 | 0.000237 |
S | 25 | P25P | ccC | ccA | 2 | 20 | B.1.177 | 0.000026 |
S | 25 | P25P | ccC | ccT | 20 | 20 | C.37 | 0.002321 |
S | 25 | P25P | ccC | ccT | 17 | 17 | AY.14 | 0.001496 |
S | 25 | P25P | ccC | ccT | 17 | 17 | AY.46.3 | 0.015873 |
S | 25 | P25P | ccC | ccT | 12 | 16 | B.1.258 | 0.000799 |
S | 25 | P25P | ccC | ccA | 4 | 16 | B.1.258 | 0.000266 |
S | 25 | P25P | ccC | ccT | 16 | 16 | B.1.351 | 0.000476 |
S | 25 | P25P | ccC | ccT | 15 | 15 | B.1.177.83 | 0.022222 |
S | 25 | P25P | ccC | ccT | 15 | 15 | B.1.36 | 0.002189 |
S | 25 | P25P | ccC | ccT | 13 | 15 | B.1.596 | 0.001133 |
S | 25 | P25P | ccC | ccA | 2 | 15 | B.1.596 | 0.000174 |
S | 25 | P25P | ccC | ccT | 13 | 13 | B.1.177.21 | 0.000994 |
S | 25 | P25P | ccC | ccT | 13 | 13 | P.1.15 | 0.00302 |
S | 25 | P25P | ccC | ccT | 12 | 12 | AY.5 | 0.000248 |
S | 25 | P25P | ccC | ccT | 12 | 12 | B.1.438.1 | 0.001287 |
S | 25 | P25P | ccC | ccT | 12 | 12 | W.2 | 0.057971 |
S | 25 | P25P | ccC | ccT | 11 | 11 | B.1.236 | 0.022587 |
S | 25 | P25P | ccC | ccT | 11 | 11 | B.1.429 | 0.000259 |
S | 25 | P25P | ccC | ccT | 10 | 10 | AY.80 | 0.011287 |
S | 25 | P25P | ccC | ccT | 10 | 10 | B.1.628 | 0.003524 |
S | 25 | P25P | ccC | ccT | 9 | 9 | B.1.1.39 | 0.004587 |
S | 25 | P25P | ccC | ccT | 9 | 9 | B.1.637 | 0.000658 |
S | 25 | P25P | ccC | ccT | 8 | 8 | AY.33 | 0.000534 |
S | 25 | P25P | ccC | ccT | 8 | 8 | AY.98.1 | 0.000387 |
S | 25 | P25P | ccC | ccT | 8 | 8 | B.1.1.354 | 0.035088 |
S | 25 | P25P | ccC | ccT | 8 | 8 | B.1.177.4 | 0.001688 |
S | 25 | P25P | ccC | ccT | 8 | 8 | B.1.221 | 0.000568 |
S | 25 | P25P | ccC | ccT | 6 | 7 | AY.102 | 0.000159 |
S | 25 | P25P | ccC | ccA | 1 | 7 | AY.102 | 0.000027 |
S | 25 | P25P | ccC | ccT | 7 | 7 | AY.3.1 | 0.000597 |
S | 25 | P25P | ccC | ccT | 7 | 7 | AY.5.3 | 0.002362 |
S | 25 | P25P | ccC | ccT | 7 | 7 | AY.61 | 0.000733 |
S | 25 | P25P | ccC | ccT | 7 | 7 | B.1.311 | 0.001922 |
S | 25 | P25P | ccC | ccT | 6 | 6 | AY.119 | 0.000212 |
S | 25 | P25P | ccC | ccT | 6 | 6 | AY.29 | 0.000095 |
S | 25 | P25P | ccC | ccT | 6 | 6 | B.1.160 | 0.000187 |
S | 25 | P25P | ccC | ccT | 6 | 6 | P.1.7 | 0.001916 |
S | 25 | P25P | ccC | ccT | 5 | 5 | AY.118 | 0.000313 |
S | 25 | P25P | ccC | ccT | 5 | 5 | AY.21 | 0.009488 |
S | 25 | P25P | ccC | ccT | 5 | 5 | AY.9 | 0.000338 |
S | 25 | P25P | ccC | ccT | 5 | 5 | AY.9.2 | 0.000184 |
S | 25 | P25P | ccC | ccT | 5 | 5 | B.1.177.50 | 0.023474 |
S | 25 | P25P | ccC | ccT | 5 | 5 | B.1.243 | 0.000348 |
S | 25 | P25P | ccC | ccT | 5 | 5 | C.36.3 | 0.002836 |
S | 25 | P25P | ccC | ccT | 5 | 5 | P.1.12 | 0.00242 |
S | 25 | P25P | ccC | ccT | 5 | 5 | Q.8 | 0.000825 |
S | 25 | P25P | ccC | ccT | 5 | 5 | R.1 | 0.00045 |
S | 25 | P25P | ccC | ccT | 2 | 4 | 0.111111 | |
S | 25 | P25P | ccC | ccA | 2 | 4 | 0.111111 | |
S | 25 | P25P | ccC | ccT | 4 | 4 | AY.4.5 | 0.00043 |
S | 25 | P25P | ccC | ccT | 4 | 4 | AY.42 | 0.000161 |
S | 25 | P25P | ccC | ccT | 4 | 4 | AY.59 | 0.002119 |
S | 25 | P25P | ccC | ccT | 4 | 4 | B.1.1.216 | 0.003562 |
S | 25 | P25P | ccC | ccT | 4 | 4 | B.1.1.263 | 0.006231 |
S | 25 | P25P | ccC | ccT | 4 | 4 | B.1.206 | 0.003263 |
S | 25 | P25P | ccC | ccT | 4 | 4 | D.2 | 0.0003 |
S | 25 | P25P | ccC | ccT | 4 | 4 | P.1.14 | 0.000191 |
S | 25 | P25P | ccC | ccT | 3 | 3 | A | 0.001161 |
S | 25 | P25P | ccC | ccT | 3 | 3 | AY.113 | 0.000427 |
S | 25 | P25P | ccC | ccT | 2 | 3 | AY.120 | 0.000074 |
S | 25 | P25P | ccC | ccA | 1 | 3 | AY.120 | 0.000037 |
S | 25 | P25P | ccC | ccT | 3 | 3 | AY.29.1 | 0.000662 |
S | 25 | P25P | ccC | ccG | 3 | 3 | AY.9.1 | 0.000251 |
S | 25 | P25P | ccC | ccT | 2 | 3 | B | 0.000256 |
S | 25 | P25P | ccC | ccA | 1 | 3 | B | 0.000128 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.1.214 | 0.000166 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.1.232 | 0.005445 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.1.25 | 0.001706 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.1.316 | 0.002775 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.36.29 | 0.001552 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.427 | 0.000151 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.437 | 0.0625 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.575 | 0.00091 |
S | 25 | P25P | ccC | ccT | 3 | 3 | B.1.621 | 0.000266 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.16 | 0.000759 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.23 | 0.000139 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.45 | 0.000243 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.46.6 | 0.000144 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.55 | 0.001835 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.69 | 0.000373 |
S | 25 | P25P | ccC | ccT | 2 | 2 | AY.98 | 0.000158 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.1.241 | 0.004141 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.1.284 | 0.000215 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.1.306 | 0.000877 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.1.63 | 0.000772 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.177.7 | 0.00033 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.177.86 | 0.000367 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.240 | 0.000431 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.346 | 0.002621 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.369 | 0.00057 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.525 | 0.000226 |
S | 25 | P25P | ccC | ccT | 2 | 2 | B.1.617.1 | 0.000258 |
S | 25 | P25P | ccC | ccT | 1 | 1 | A.18 | 0.05 |
S | 25 | P25P | ccC | ccT | 1 | 1 | A.2.5 | 0.000499 |
S | 25 | P25P | ccC | ccT | 1 | 1 | A.23.1 | 0.000704 |
S | 25 | P25P | ccC | ccT | 1 | 1 | A.6 | 0.005128 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.101 | 0.00049 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.106 | 0.000335 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.116.1 | 0.000311 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.117 | 0.000085 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.27 | 0.000065 |
S | 25 | P25P | ccC | ccG | 1 | 1 | AY.38 | 0.000499 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.39.1 | 0.00004 |
S | 25 | P25P | ccC | ccA | 1 | 1 | AY.39.2 | 0.001541 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.40 | 0.000964 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.46 | 0.000104 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.46.4 | 0.000165 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.49 | 0.003195 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.6 | 0.000041 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.63 | 0.000387 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.7.1 | 0.000113 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.75 | 0.000056 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.75.1 | 0.00018 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.84 | 0.000437 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.85 | 0.000427 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.90 | 0.000684 |
S | 25 | P25P | ccC | ccT | 1 | 1 | AY.93 | 0.000273 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.1 | 0.000327 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.192 | 0.002309 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.198 | 0.001468 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.227 | 0.004348 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.240 | 0.004695 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.277 | 0.000759 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.294 | 0.001266 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.311 | 0.000358 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.33 | 0.000421 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.344 | 0.010753 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.348 | 0.000796 |
S | 25 | P25P | ccC | ccA | 1 | 1 | B.1.1.380 | 0.009804 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.50 | 0.000679 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.1.517 | 0.006803 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.105 | 0.009615 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.110 | 0.004525 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.111 | 0.001175 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.119 | 0.010526 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.149 | 0.003425 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.177.12 | 0.000152 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.177.17 | 0.000821 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.177.57 | 0.000281 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.177.6 | 0.000977 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.177.60 | 0.000218 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.177.84 | 0.006667 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.241 | 0.000812 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.258.14 | 0.00098 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.258.7 | 0.001912 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.351.2 | 0.000303 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.36.8 | 0.001 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.361 | 0.001289 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.367 | 0.000792 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.400 | 0.000429 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.448 | 0.002625 |
S | 25 | P25P | ccC | ccA | 1 | 1 | B.1.459 | 0.004082 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.466.2 | 0.000391 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.467 | 0.04 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.470 | 0.001404 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.517 | 0.000427 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.523 | 0.002451 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.564 | 0.000426 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.565 | 0.00081 |
S | 25 | P25P | ccC | ccG | 1 | 1 | B.1.582 | 0.000491 |
S | 25 | P25P | ccC | ccA | 1 | 1 | B.1.595 | 0.000261 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.596.1 | 0.009346 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.609 | 0.000479 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.1.8 | 0.001972 |
S | 25 | P25P | ccC | ccT | 1 | 1 | B.13 | 0.045455 |
S | 25 | P25P | ccC | ccA | 1 | 1 | B.40 | 0.000364 |
S | 25 | P25P | ccC | ccT | 1 | 1 | P.1.1 | 0.000318 |
S | 25 | P25P | ccC | ccT | 1 | 1 | P.1.10 | 0.000269 |
S | 25 | P25P | ccC | ccT | 1 | 1 | P.1.4 | 0.000977 |
S | 25 | P25P | ccC | ccT | 1 | 1 | Q.1 | 0.000126 |
S | 25 | P25P | ccC | ccT | 1 | 1 | Q.3 | 0.000145 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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