CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = N440K

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S440N440KnonsynaaTaaG872061050.70011522880-22882
S440N440KnonsynaaTaaA872026150.29988522880-22882

Details of the mutation N440K within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S440N440KaaTaaG61058720All0.001168
S440N440KaaTaaA26158720All0.0005
S440N440KaaTaaA22382238B.1.6280.788584
S440N440KaaTaaG15481548B.1.619.10.992944
S440N440KaaTaaG13821382B.1.36.290.714951
S440N440KaaTaaG992992B.1.6190.864111
S440N440KaaTaaG821821B.1.1.4200.825956
S440N440KaaTaaG379379B.1.6250.891765
S440N440KaaTaaG173250B.10.001585
S440N440KaaTaaA77250B.10.000705
S440N440KaaTaaA243243B.1.6310.818182
S440N440KaaTaaG210210B.1.6340.719178
S440N440KaaTaaG140140B.1.20.001233
S440N440KaaTaaG9898B.1.360.014298
S440N440KaaTaaG6669B.1.10.001197
S440N440KaaTaaA369B.1.10.000054
S440N440KaaTaaG5858B.1.1.2160.051647
S440N440KaaTaaG3839B.1.1.70.000034
S440N440KaaTaaA139B.1.1.70.000001
S440N440KaaTaaG3232C.370.003714
S440N440KaaTaaG1919B.1.36.170.009387
S440N440KaaTaaG1515B.1.4560.04902
S440N440KaaTaaA1414B.1.6270.028283
S440N440KaaTaaG1112B.1.5960.000959
S440N440KaaTaaA112B.1.5960.000087
S440N440KaaTaaA1011P.1.120.00484
S440N440KaaTaaG111P.1.120.000484
S440N440KaaTaaG99AY.1010.004414
S440N440KaaTaaG66B.1.1280.003812
S440N440KaaTaaG66C.1.20.025532
S440N440KaaTaaG45B.1.2470.059701
S440N440KaaTaaA15B.1.2470.014925
S440N440KaaTaaG44AY.450.000487
S440N440KaaTaaG44B.1.2140.014652
S440N440KaaTaaG44B.1.6380.210526
S440N440KaaTaaG33AT.10.015385
S440N440KaaTaaG33AY.40.000005
S440N440KaaTaaA23AY.430.000009
S440N440KaaTaaG13AY.430.000004
S440N440KaaTaaA33AY.440.000018
S440N440KaaTaaA33B.1.1.3170.001235
S440N440KaaTaaG33B.1.1.4090.008499
S440N440KaaTaaG33B.1.1600.000094
S440N440KaaTaaG33B.1.1700.012931
S440N440KaaTaaG33B.1.2600.010033
S440N440KaaTaaG33B.1.36.160.004274
S440N440KaaTaaG33B.1.4620.021739
S440N440KaaTaaG33B.1.9.50.017045
S440N440KaaTaaG33C.140.012987
S440N440KaaTaaA22AY.250.000012
S440N440KaaTaaG22B0.000256
S440N440KaaTaaG22B.1.1.280.000622
S440N440KaaTaaG22B.1.1.830.00542
S440N440KaaTaaG22B.1.1570.00597
S440N440KaaTaaA12B.1.177.730.000566
S440N440KaaTaaG12B.1.177.730.000566
S440N440KaaTaaG22B.1.3690.00057
S440N440KaaTaaG22B.1.4600.035714
S440N440KaaTaaG22B.1.4650.007605
S440N440KaaTaaA22B.1.617.10.000258
S440N440KaaTaaG12B.1.617.20.000004
S440N440KaaTaaA12B.1.617.20.000004
S440N440KaaTaaG22C.36.3.10.005435
S440N440KaaTaaG22P.1.160.000748
S440N440KaaTaaG11A.2.50.000499
S440N440KaaTaaG11A.230.010526
S440N440KaaTaaA11AY.130.000161
S440N440KaaTaaA11AY.290.000016
S440N440KaaTaaA11AY.470.000031
S440N440KaaTaaA11AY.620.000436
S440N440KaaTaaG11AY.99.20.000092
S440N440KaaTaaA11B.1.1.1170.009709
S440N440KaaTaaA11B.1.1.1610.003534
S440N440KaaTaaG11B.1.1.1740.003378
S440N440KaaTaaG11B.1.1.2000.007463
S440N440KaaTaaG11B.1.1.2540.011236
S440N440KaaTaaG11B.1.1.2790.001121
S440N440KaaTaaG11B.1.1.3040.002809
S440N440KaaTaaG11B.1.1.3070.002532
S440N440KaaTaaG11B.1.1.3110.000358
S440N440KaaTaaG11B.1.1.3260.001761
S440N440KaaTaaG11B.1.1.3480.000796
S440N440KaaTaaG11B.1.1.370.000193
S440N440KaaTaaG11B.1.1.4170.002703
S440N440KaaTaaG11B.1.1.4480.002033
S440N440KaaTaaA11B.1.1.4590.015385
S440N440KaaTaaG11B.1.1.560.017857
S440N440KaaTaaG11B.1.1.570.011494
S440N440KaaTaaG11B.1.214.20.0006
S440N440KaaTaaA11B.1.2210.000071
S440N440KaaTaaA11B.1.3200.001245
S440N440KaaTaaG11B.1.3510.00003
S440N440KaaTaaG11B.1.36.100.004785
S440N440KaaTaaG11B.1.36.190.009259
S440N440KaaTaaG11B.1.36.20.010753
S440N440KaaTaaG11B.1.36.220.001208
S440N440KaaTaaG11B.1.36.240.006173
S440N440KaaTaaG11B.1.36.310.001751
S440N440KaaTaaA11B.1.3670.000792
S440N440KaaTaaA11B.1.3990.001934
S440N440KaaTaaG11B.1.4270.00005
S440N440KaaTaaG11B.1.4320.011236
S440N440KaaTaaG11B.1.5330.009615
S440N440KaaTaaG11B.1.5480.035714
S440N440KaaTaaG11B.1.5610.000397
S440N440KaaTaaA11B.1.6370.000073
S440N440KaaTaaG11B.4.10.018868
S440N440KaaTaaG11C.37.10.002618
S440N440KaaTaaG11P.10.000016
S440N440KaaTaaA11P.1.100.000269
S440N440KaaTaaG11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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