CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = M177I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S177M177InonsynatGatA804433370.41484322091-22093
S177M177InonsynatGatT804425090.31190922091-22093
S177M177InonsynatGatC804421980.27324722091-22093

Details of the mutation M177I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S177M177IatGatA33378044All0.000638
S177M177IatGatT25098044All0.00048
S177M177IatGatC21988044All0.00042
S177M177IatGatA26592694AY.30.026447
S177M177IatGatC192694AY.30.000189
S177M177IatGatT162694AY.30.000159
S177M177IatGatT12041209AY.260.034085
S177M177IatGatC41209AY.260.000113
S177M177IatGatA11209AY.260.000028
S177M177IatGatC6201007B.1.1.70.000555
S177M177IatGatT2961007B.1.1.70.000265
S177M177IatGatA911007B.1.1.70.000081
S177M177IatGatT145293AY.250.000872
S177M177IatGatA139293AY.250.000836
S177M177IatGatC9293AY.250.000054
S177M177IatGatC140278AY.40.000218
S177M177IatGatT105278AY.40.000163
S177M177IatGatA33278AY.40.000051
S177M177IatGatC173270B.1.20.001523
S177M177IatGatT80270B.1.20.000704
S177M177IatGatA17270B.1.20.00015
S177M177IatGatC230231B.1.5960.020042
S177M177IatGatT1231B.1.5960.000087
S177M177IatGatC110226B.1.617.20.000414
S177M177IatGatA93226B.1.617.20.00035
S177M177IatGatT23226B.1.617.20.000087
S177M177IatGatT152154AY.60.006252
S177M177IatGatC1154AY.60.000041
S177M177IatGatA1154AY.60.000041
S177M177IatGatT88150AY.440.000536
S177M177IatGatC52150AY.440.000317
S177M177IatGatA10150AY.440.000061
S177M177IatGatC146146Q.30.021175
S177M177IatGatC129129AY.220.269874
S177M177IatGatC8082B.1.6210.007082
S177M177IatGatT282B.1.6210.000177
S177M177IatGatT6277AY.1030.000385
S177M177IatGatC1277AY.1030.000075
S177M177IatGatA377AY.1030.000019
S177M177IatGatC6668AY.1000.003036
S177M177IatGatA168AY.1000.000046
S177M177IatGatT168AY.1000.000046
S177M177IatGatT6064AY.4.20.001301
S177M177IatGatC464AY.4.20.000087
S177M177IatGatC5960B.1.1770.000777
S177M177IatGatT160B.1.1770.000013
S177M177IatGatT2239AY.430.000097
S177M177IatGatC939AY.430.00004
S177M177IatGatA839AY.430.000035
S177M177IatGatC2837B.10.000256
S177M177IatGatT837B.10.000073
S177M177IatGatA137B.10.000009
S177M177IatGatA1436AY.1020.000371
S177M177IatGatC1336AY.1020.000345
S177M177IatGatT936AY.1020.000239
S177M177IatGatA3535B.1.258.150.660377
S177M177IatGatA2828B.1.1.1680.736842
S177M177IatGatC2328B.1.5260.000541
S177M177IatGatT428B.1.5260.000094
S177M177IatGatA128B.1.5260.000024
S177M177IatGatT1428P.10.000221
S177M177IatGatA828P.10.000126
S177M177IatGatC628P.10.000095
S177M177IatGatC1724AY.1130.002421
S177M177IatGatT724AY.1130.000997
S177M177IatGatT2323B.1.1310.201754
S177M177IatGatA1718AY.920.004884
S177M177IatGatT118AY.920.000287
S177M177IatGatC1217P.1.150.002788
S177M177IatGatA517P.1.150.001162
S177M177IatGatA815B.1.10.000145
S177M177IatGatC515B.1.10.000091
S177M177IatGatT215B.1.10.000036
S177M177IatGatT1515B.1.3050.032258
S177M177IatGatC1414AZ.30.021277
S177M177IatGatA1214P.1.10.003812
S177M177IatGatT214P.1.10.000635
S177M177IatGatT813B.1.4290.000188
S177M177IatGatC513B.1.4290.000118
S177M177IatGatA912AY.1170.000761
S177M177IatGatC312AY.1170.000254
S177M177IatGatA912AY.1190.000318
S177M177IatGatC212AY.1190.000071
S177M177IatGatT112AY.1190.000035
S177M177IatGatA612B.1.1600.000187
S177M177IatGatT612B.1.1600.000187
S177M177IatGatC1212Q.10.001516
S177M177IatGatA1011AY.340.00097
S177M177IatGatC111AY.340.000097
S177M177IatGatT711AY.390.000173
S177M177IatGatC311AY.390.000074
S177M177IatGatA111AY.390.000025
S177M177IatGatA1011AY.840.004374
S177M177IatGatT111AY.840.000437
S177M177IatGatC811AY.98.10.000387
S177M177IatGatT311AY.98.10.000145
S177M177IatGatT911B.1.1.2430.036735
S177M177IatGatC211B.1.1.2430.008163
S177M177IatGatA510AY.290.000079
S177M177IatGatC510AY.290.000079
S177M177IatGatT410AY.50.000083
S177M177IatGatA410AY.50.000083
S177M177IatGatC210AY.50.000041
S177M177IatGatC610B.1.2430.000418
S177M177IatGatT410B.1.2430.000278
S177M177IatGatA1010B.1.2770.238095
S177M177IatGatA99AY.530.002588
S177M177IatGatC79B0.000895
S177M177IatGatA19B0.000128
S177M177IatGatT19B0.000128
S177M177IatGatC59B.1.2580.000333
S177M177IatGatT49B.1.2580.000266
S177M177IatGatT59B.1.3510.000149
S177M177IatGatC49B.1.3510.000119
S177M177IatGatA48AY.420.000161
S177M177IatGatT38AY.420.000121
S177M177IatGatC18AY.420.00004
S177M177IatGatC78B.1.2210.000497
S177M177IatGatT18B.1.2210.000071
S177M177IatGatT88P.1.160.002993
S177M177IatGatA37AY.130.000483
S177M177IatGatC27AY.130.000322
S177M177IatGatT27AY.130.000322
S177M177IatGatT37AY.200.000117
S177M177IatGatC37AY.200.000117
S177M177IatGatA17AY.200.000039
S177M177IatGatA66AY.1050.003859
S177M177IatGatA46AY.470.000124
S177M177IatGatT26AY.470.000062
S177M177IatGatA66AY.570.003937
S177M177IatGatC56B.1.1.5190.000199
S177M177IatGatT16B.1.1.5190.00004
S177M177IatGatC66B.1.177.200.009105
S177M177IatGatC66B.1.3490.004289
S177M177IatGatC46P.1.140.000191
S177M177IatGatA26P.1.140.000096
S177M177IatGatA45AY.230.000279
S177M177IatGatT15AY.230.00007
S177M177IatGatC55AY.46.60.000361
S177M177IatGatC55B.1.1.1700.006234
S177M177IatGatT35B.400.001093
S177M177IatGatA25B.400.000729
S177M177IatGatA55C.36.30.002836
S177M177IatGatT45D.20.0003
S177M177IatGatA15D.20.000075
S177M177IatGatT240.111111
S177M177IatGatC240.111111
S177M177IatGatC44AY.140.000352
S177M177IatGatA24AY.270.000129
S177M177IatGatC14AY.270.000065
S177M177IatGatT14AY.270.000065
S177M177IatGatT24AY.450.000243
S177M177IatGatC14AY.450.000122
S177M177IatGatA14AY.450.000122
S177M177IatGatA24AY.610.00021
S177M177IatGatT14AY.610.000105
S177M177IatGatC14AY.610.000105
S177M177IatGatC34AY.90.000203
S177M177IatGatT14AY.90.000068
S177M177IatGatA34AY.910.002191
S177M177IatGatC14AY.910.00073
S177M177IatGatT44B.1.1.2190.02
S177M177IatGatC44B.1.177.170.003284
S177M177IatGatA44B.1.177.690.005935
S177M177IatGatC44B.1.3670.00317
S177M177IatGatT44B.1.4040.005208
S177M177IatGatT24B.1.5250.000226
S177M177IatGatC24B.1.5250.000226
S177M177IatGatT24Q.80.00033
S177M177IatGatA24Q.80.00033
S177M177IatGatT23AE.80.000978
S177M177IatGatC13AE.80.000489
S177M177IatGatT33AY.1040.005952
S177M177IatGatC33AY.39.10.000119
S177M177IatGatC33AY.460.000312
S177M177IatGatC33AY.680.000821
S177M177IatGatA23AY.880.001768
S177M177IatGatC13AY.880.000884
S177M177IatGatT23B.1.1.10.000653
S177M177IatGatC13B.1.1.10.000327
S177M177IatGatT23B.1.177.40.000422
S177M177IatGatA13B.1.177.40.000211
S177M177IatGatC23B.1.2340.000264
S177M177IatGatT13B.1.2340.000132
S177M177IatGatC23B.1.3970.009709
S177M177IatGatT13B.1.3970.004854
S177M177IatGatC23B.1.5950.000522
S177M177IatGatT13B.1.5950.000261
S177M177IatGatT33C.370.000348
S177M177IatGatT33C.60.111111
S177M177IatGatT22A.2.50.000998
S177M177IatGatA22AY.1180.000125
S177M177IatGatT22AY.1210.000271
S177M177IatGatC12AY.23.10.000417
S177M177IatGatT12AY.23.10.000417
S177M177IatGatC22AY.330.000134
S177M177IatGatT12AY.5.30.000337
S177M177IatGatA12AY.5.30.000337
S177M177IatGatC22AY.690.000373
S177M177IatGatC22AY.750.000112
S177M177IatGatT22AY.75.10.000361
S177M177IatGatT12AY.930.000273
S177M177IatGatA12AY.930.000273
S177M177IatGatA22AY.960.004149
S177M177IatGatC22AZ.50.007018
S177M177IatGatT22B.1.1.1280.014184
S177M177IatGatC22B.1.1.2160.001781
S177M177IatGatC22B.1.1.2410.004141
S177M177IatGatC22B.1.1.250.001137
S177M177IatGatC12B.1.1.3180.000302
S177M177IatGatT12B.1.1.3180.000302
S177M177IatGatT22B.1.1.3290.007692
S177M177IatGatC22B.1.1.4130.013793
S177M177IatGatT22B.1.177.550.004662
S177M177IatGatC22B.1.177.820.000955
S177M177IatGatA22B.1.36.180.00084
S177M177IatGatT12B.1.4200.010417
S177M177IatGatC12B.1.4200.010417
S177M177IatGatC12B.1.4270.00005
S177M177IatGatT12B.1.4270.00005
S177M177IatGatT12B.1.466.20.000391
S177M177IatGatC12B.1.466.20.000391
S177M177IatGatC22B.1.5800.00813
S177M177IatGatC22B.1.617.10.000258
S177M177IatGatT12B.1.6230.000536
S177M177IatGatC12B.1.6230.000536
S177M177IatGatT22B.4.20.133333
S177M177IatGatC12N.50.001767
S177M177IatGatA12N.50.001767
S177M177IatGatC12P.1.170.000162
S177M177IatGatT12P.1.170.000162
S177M177IatGatT12P.20.000187
S177M177IatGatA12P.20.000187
S177M177IatGatC12Q.40.000455
S177M177IatGatT12Q.40.000455
S177M177IatGatT11A.180.05
S177M177IatGatA11A.30.002096
S177M177IatGatC11AD.20.000219
S177M177IatGatC11AY.1010.00049
S177M177IatGatT11AY.1110.000183
S177M177IatGatA11AY.1200.000037
S177M177IatGatT11AY.120.10.000321
S177M177IatGatA11AY.3.10.000085
S177M177IatGatC11AY.300.000396
S177M177IatGatC11AY.360.000148
S177M177IatGatA11AY.380.000499
S177M177IatGatC11AY.46.40.000165
S177M177IatGatA11AY.480.000465
S177M177IatGatA11AY.550.000917
S177M177IatGatC11AY.600.000938
S177M177IatGatT11AY.620.000436
S177M177IatGatT11AY.640.000595
S177M177IatGatC11AY.670.000464
S177M177IatGatT11AY.7.20.000559
S177M177IatGatC11AY.700.000209
S177M177IatGatC11AY.9.20.000037
S177M177IatGatA11AY.980.000079
S177M177IatGatC11AY.99.20.000092
S177M177IatGatT11B.1.1.1570.000913
S177M177IatGatT11B.1.1.2010.02439
S177M177IatGatA11B.1.1.2070.001182
S177M177IatGatC11B.1.1.2140.000055
S177M177IatGatC11B.1.1.2180.007692
S177M177IatGatC11B.1.1.2220.000204
S177M177IatGatT11B.1.1.280.000311
S177M177IatGatT11B.1.1.2840.000107
S177M177IatGatC11B.1.1.3260.001761
S177M177IatGatT11B.1.1.3720.000689
S177M177IatGatT11B.1.1.3910.008547
S177M177IatGatA11B.1.1.4320.001266
S177M177IatGatC11B.1.1.440.00241
S177M177IatGatT11B.1.1.500.000679
S177M177IatGatT11B.1.1110.001175
S177M177IatGatC11B.1.1470.000756
S177M177IatGatC11B.1.177.100.000878
S177M177IatGatC11B.1.177.650.000665
S177M177IatGatC11B.1.177.730.000566
S177M177IatGatC11B.1.177.740.015152
S177M177IatGatC11B.1.214.20.0006
S177M177IatGatT11B.1.2370.004975
S177M177IatGatA11B.1.2400.000216
S177M177IatGatT11B.1.258.140.00098
S177M177IatGatA11B.1.2940.032258
S177M177IatGatT11B.1.3380.008621
S177M177IatGatC11B.1.360.000146
S177M177IatGatT11B.1.36.100.004785
S177M177IatGatT11B.1.36.290.000517
S177M177IatGatT11B.1.36.80.001
S177M177IatGatC11B.1.3600.012658
S177M177IatGatC11B.1.3800.006623
S177M177IatGatT11B.1.3980.002976
S177M177IatGatT11B.1.4150.014286
S177M177IatGatC11B.1.438.10.000107
S177M177IatGatC11B.1.5170.000427
S177M177IatGatC11B.1.5650.00081
S177M177IatGatT11B.1.5810.009434
S177M177IatGatC11B.1.5820.000491
S177M177IatGatC11B.1.6090.000479
S177M177IatGatA11B.1.6370.000073
S177M177IatGatC11B.190.037037
S177M177IatGatA11B.4.40.018868
S177M177IatGatC11C.160.00106
S177M177IatGatC11P.1.120.000484
S177M177IatGatC11P.1.40.000977
S177M177IatGatC11Q.60.006623
S177M177IatGatC11W.10.008696
S177M177IatGatC11Y.10.012821

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.