CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 153 | M153T | nonsyn | aTg | aCg | 10286 | 10264 | 0.997861 | 22019-22021 | |
S | 153 | M153T | nonsyn | aTG | aCT | 10286 | 20 | 0.00194439 | 22019-22021 | |
S | 153 | M153T | nonsyn | aTG | aCA | 10286 | 1 | 0.0000972195 | 22019-22021 | |
S | 153 | M153T | nonsyn | aTG | aCC | 10286 | 1 | 0.0000972195 | 22019-22021 |
Details of the mutation M153T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 153 | M153T | aTg | aCg | 10264 | 10286 | All | 0.001963 |
S | 153 | M153T | aTG | aCT | 20 | 10286 | All | 0.000004 |
S | 153 | M153T | aTG | aCC | 1 | 10286 | All | 0 |
S | 153 | M153T | aTG | aCA | 1 | 10286 | All | 0 |
S | 153 | M153T | aTg | aCg | 4973 | 4977 | B.1.1.284 | 0.534099 |
S | 153 | M153T | aTG | aCT | 4 | 4977 | B.1.1.284 | 0.00043 |
S | 153 | M153T | aTg | aCg | 900 | 902 | B.1.1 | 0.016327 |
S | 153 | M153T | aTG | aCT | 2 | 902 | B.1.1 | 0.000036 |
S | 153 | M153T | aTg | aCg | 727 | 727 | B.1.1.7 | 0.000651 |
S | 153 | M153T | aTg | aCg | 702 | 702 | B.1 | 0.00643 |
S | 153 | M153T | aTg | aCg | 473 | 473 | B.1.1.141 | 0.95171 |
S | 153 | M153T | aTg | aCg | 431 | 444 | B.1.627 | 0.870707 |
S | 153 | M153T | aTG | aCT | 13 | 444 | B.1.627 | 0.026263 |
S | 153 | M153T | aTg | aCg | 410 | 410 | B.1.1.397 | 0.923423 |
S | 153 | M153T | aTg | aCg | 311 | 311 | B.1.1.280 | 0.959877 |
S | 153 | M153T | aTg | aCg | 277 | 277 | B.1.1.28 | 0.086212 |
S | 153 | M153T | aTg | aCg | 131 | 131 | B.1.632 | 0.879195 |
S | 153 | M153T | aTg | aCg | 64 | 64 | B.1.36 | 0.009338 |
S | 153 | M153T | aTg | aCg | 45 | 45 | AY.25 | 0.000271 |
S | 153 | M153T | aTg | aCg | 45 | 45 | B.1.639 | 0.978261 |
S | 153 | M153T | aTg | aCg | 43 | 43 | B.1.1.343 | 0.895833 |
S | 153 | M153T | aTg | aCg | 33 | 33 | B.1.1.83 | 0.089431 |
S | 153 | M153T | aTg | aCg | 31 | 31 | N.5 | 0.05477 |
S | 153 | M153T | aTg | aCg | 28 | 28 | AY.3.1 | 0.002387 |
S | 153 | M153T | aTg | aCg | 23 | 23 | B.1.617.2 | 0.000087 |
S | 153 | M153T | aTg | aCg | 22 | 22 | B.1.1.160 | 0.52381 |
S | 153 | M153T | aTg | aCg | 22 | 22 | B.1.1.396 | 1 |
S | 153 | M153T | aTg | aCg | 22 | 22 | B.1.595 | 0.005741 |
S | 153 | M153T | aTg | aCg | 18 | 18 | B.1.1.409 | 0.050992 |
S | 153 | M153T | aTg | aCg | 18 | 18 | B.1.2 | 0.000158 |
S | 153 | M153T | aTg | aCg | 17 | 17 | B.1.1.319 | 0.298246 |
S | 153 | M153T | aTg | aCg | 17 | 17 | B.1.177.16 | 0.011296 |
S | 153 | M153T | aTg | aCg | 16 | 16 | B.1.1.330 | 1 |
S | 153 | M153T | aTg | aCg | 16 | 16 | B.1.525 | 0.001811 |
S | 153 | M153T | aTg | aCg | 14 | 14 | AY.44 | 0.000085 |
S | 153 | M153T | aTg | aCg | 14 | 14 | P.2 | 0.002613 |
S | 153 | M153T | aTg | aCg | 13 | 13 | AY.102 | 0.000345 |
S | 153 | M153T | aTg | aCg | 13 | 13 | B.1.1.203 | 0.220339 |
S | 153 | M153T | aTg | aCg | 12 | 12 | AY.42 | 0.000483 |
S | 153 | M153T | aTg | aCg | 11 | 11 | B.1.177 | 0.000145 |
S | 153 | M153T | aTg | aCg | 11 | 11 | B.1.509 | 0.009524 |
S | 153 | M153T | aTg | aCg | 10 | 10 | A.19 | 0.09434 |
S | 153 | M153T | aTg | aCg | 10 | 10 | AY.34 | 0.00097 |
S | 153 | M153T | aTg | aCg | 10 | 10 | B.1.258 | 0.000665 |
S | 153 | M153T | aTg | aCg | 9 | 9 | AY.35 | 0.002097 |
S | 153 | M153T | aTg | aCg | 9 | 9 | AY.4 | 0.000014 |
S | 153 | M153T | aTg | aCg | 9 | 9 | B.1.1.135 | 0.042254 |
S | 153 | M153T | aTg | aCg | 8 | 8 | B | 0.001022 |
S | 153 | M153T | aTg | aCg | 8 | 8 | B.1.1.291 | 0.005939 |
S | 153 | M153T | aTg | aCg | 8 | 8 | B.1.336 | 0.019512 |
S | 153 | M153T | aTg | aCg | 6 | 8 | P.1 | 0.000095 |
S | 153 | M153T | aTG | aCT | 1 | 8 | P.1 | 0.000016 |
S | 153 | M153T | aTG | aCA | 1 | 8 | P.1 | 0.000016 |
S | 153 | M153T | aTg | aCg | 7 | 7 | AY.47 | 0.000218 |
S | 153 | M153T | aTg | aCg | 7 | 7 | AY.9.1 | 0.000586 |
S | 153 | M153T | aTg | aCg | 7 | 7 | B.1.429 | 0.000165 |
S | 153 | M153T | aTg | aCg | 6 | 6 | AL.1 | 0.077922 |
S | 153 | M153T | aTg | aCg | 6 | 6 | B.1.1.51 | 0.010309 |
S | 153 | M153T | aTg | aCg | 5 | 5 | A.2.5 | 0.002495 |
S | 153 | M153T | aTg | aCg | 5 | 5 | AY.3 | 0.00005 |
S | 153 | M153T | aTg | aCg | 5 | 5 | B.1.1.398 | 0.016129 |
S | 153 | M153T | aTg | aCg | 5 | 5 | B.1.1.446 | 0.384615 |
S | 153 | M153T | aTg | aCg | 5 | 5 | B.1.1.452 | 0.555556 |
S | 153 | M153T | aTg | aCg | 5 | 5 | B.1.1.519 | 0.000199 |
S | 153 | M153T | aTg | aCg | 5 | 5 | B.1.210 | 0.010661 |
S | 153 | M153T | aTg | aCg | 5 | 5 | B.1.551 | 0.006452 |
S | 153 | M153T | aTg | aCg | 5 | 5 | P.5 | 0.068493 |
S | 153 | M153T | aTg | aCg | 5 | 5 | Q.8 | 0.000825 |
S | 153 | M153T | aTg | aCg | 4 | 4 | AY.39 | 0.000099 |
S | 153 | M153T | aTg | aCg | 4 | 4 | B.1.1.161 | 0.014134 |
S | 153 | M153T | aTg | aCg | 4 | 4 | B.1.1.37 | 0.000771 |
S | 153 | M153T | aTg | aCg | 4 | 4 | B.1.1.370 | 0.050633 |
S | 153 | M153T | aTg | aCg | 4 | 4 | B.1.433 | 0.01278 |
S | 153 | M153T | aTg | aCg | 4 | 4 | B.1.609 | 0.001918 |
S | 153 | M153T | aTg | aCg | 4 | 4 | Q.1 | 0.000505 |
S | 153 | M153T | aTg | aCg | 3 | 3 | AY.119 | 0.000106 |
S | 153 | M153T | aTg | aCg | 3 | 3 | AY.33 | 0.0002 |
S | 153 | M153T | aTg | aCg | 3 | 3 | AY.4.2 | 0.000065 |
S | 153 | M153T | aTg | aCg | 3 | 3 | AY.43 | 0.000013 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.1.253 | 0.007519 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.1.31 | 0.2 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.1.54 | 0.009063 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.124 | 0.023438 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.22 | 0.003953 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.356 | 0.005181 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.6 | 0.051724 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.634 | 0.010274 |
S | 153 | M153T | aTg | aCg | 3 | 3 | B.1.637 | 0.000219 |
S | 153 | M153T | aTg | aCg | 3 | 3 | N.3 | 0.017442 |
S | 153 | M153T | aTg | aCg | 2 | 2 | 0.111111 | |
S | 153 | M153T | aTg | aCg | 2 | 2 | AB.1 | 0.016393 |
S | 153 | M153T | aTg | aCg | 2 | 2 | AY.7.1 | 0.000225 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.117 | 0.019417 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.148 | 0.017544 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.170 | 0.002494 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.277 | 0.001517 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.317 | 0.000823 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.33 | 0.000842 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.453 | 0.016949 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.1.523 | 0.003125 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.143 | 0.042553 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.177.44 | 0.001038 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.177.60 | 0.000437 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.298 | 0.004228 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.311 | 0.000549 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.36.29 | 0.001035 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.360 | 0.025316 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.388 | 0.181818 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.558 | 0.009132 |
S | 153 | M153T | aTg | aCg | 2 | 2 | B.1.623 | 0.001073 |
S | 153 | M153T | aTg | aCg | 2 | 2 | P.1.15 | 0.000465 |
S | 153 | M153T | aTg | aCg | 2 | 2 | P.6 | 0.006289 |
S | 153 | M153T | aTg | aCg | 1 | 1 | A.1 | 0.000282 |
S | 153 | M153T | aTg | aCg | 1 | 1 | A.2.5.2 | 0.001572 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.114 | 0.000231 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.118 | 0.000063 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.121 | 0.000135 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.13 | 0.000161 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.23 | 0.00007 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.23.1 | 0.000417 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.26 | 0.000028 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.4.5 | 0.000107 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.5.3 | 0.000337 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.64 | 0.000595 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.71 | 0.000475 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.74 | 0.000116 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.92 | 0.000287 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.95 | 0.000761 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.98 | 0.000079 |
S | 153 | M153T | aTg | aCg | 1 | 1 | AY.99 | 0.001049 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.129 | 0.009174 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.189 | 0.001513 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.192 | 0.002309 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.194 | 0.00495 |
S | 153 | M153T | aTG | aCC | 1 | 1 | B.1.1.207 | 0.001182 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.214 | 0.000055 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.216 | 0.00089 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.220 | 0.001859 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.222 | 0.000204 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.265 | 0.003155 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.269 | 0.001353 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.272 | 0.005208 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.282 | 0.011628 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.294 | 0.001266 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.300 | 0.010753 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.311 | 0.000358 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.316 | 0.000925 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.413 | 0.006897 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.419 | 0.007407 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.432 | 0.001266 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.437 | 0.010417 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.485 | 0.016667 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.56 | 0.017857 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.74 | 0.00431 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.89 | 0.006061 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.1.99 | 0.02381 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.160 | 0.000031 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.177.73 | 0.000566 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.177.86 | 0.000183 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.221 | 0.000071 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.221.1 | 0.002907 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.240 | 0.000216 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.302 | 0.013333 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.340 | 0.004292 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.341 | 0.022727 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.349 | 0.000715 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.367 | 0.000792 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.375 | 0.00082 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.396 | 0.000706 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.400 | 0.000429 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.417 | 0.028571 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.427 | 0.00005 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.443 | 0.004673 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.452 | 0.013699 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.480 | 0.002488 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.503 | 0.002488 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.526 | 0.000024 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.533 | 0.009615 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.596 | 0.000087 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.617.1 | 0.000129 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.618 | 0.004032 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.8 | 0.001972 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.1.81 | 0.021277 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.29 | 0.003509 |
S | 153 | M153T | aTg | aCg | 1 | 1 | B.6 | 0.00091 |
S | 153 | M153T | aTg | aCg | 1 | 1 | C.37 | 0.000116 |
S | 153 | M153T | aTg | aCg | 1 | 1 | N.9 | 0.005952 |
S | 153 | M153T | aTg | aCg | 1 | 1 | P.1.1 | 0.000318 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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