CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = L452L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S452L452LsynctGctT313726480.84411922916-22918
S452L452LsynCtgTtg31373040.096907922916-22918
S452L452LsynctGctA31371640.052279222916-22918
S452L452LsynCtGTtA3137190.0060567422916-22918
S452L452LsynctGctC313720.00063755222916-22918

Details of the mutation L452L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S452L452LctGctT26483137All0.000506
S452L452LCtgTtg3043137All0.000058
S452L452LctGctA1643137All0.000031
S452L452LCtGTtA193137All0.000004
S452L452LctGctC23137All0
S452L452LctGctT386641B.1.1.70.000346
S452L452LCtgTtg150641B.1.1.70.000134
S452L452LctGctA104641B.1.1.70.000093
S452L452LctGctC1641B.1.1.70.000001
S452L452LctGctT607607B.1.36.380.996716
S452L452LctGctT387415B.1.20.003408
S452L452LCtgTtg23415B.1.20.000203
S452L452LctGctA5415B.1.20.000044
S452L452LctGctT324324B.1.1.2980.27931
S452L452LctGctT196198B.1.1600.006113
S452L452LctGctA2198B.1.1600.000062
S452L452LctGctT139139P.1.100.037456
S452L452LctGctT7070B.1.36.20.752688
S452L452LctGctT5050B.1.1.3050.19305
S452L452LctGctA2646P.10.00041
S452L452LctGctT2046P.10.000315
S452L452LctGctT3544B.10.000321
S452L452LCtgTtg544B.10.000046
S452L452LctGctA344B.10.000027
S452L452LCtGTtA144B.10.000009
S452L452LctGctT3739B.1.5250.004187
S452L452LCtgTtg239B.1.5250.000226
S452L452LCtgTtg3232A.290.170213
S452L452LctGctT2028B.1.10.000363
S452L452LCtgTtg628B.1.10.000109
S452L452LctGctA228B.1.10.000036
S452L452LctGctT2527P.1.140.001195
S452L452LctGctA227P.1.140.000096
S452L452LctGctT2727Q.40.012278
S452L452LctGctT2326B.1.1770.000303
S452L452LCtgTtg226B.1.1770.000026
S452L452LctGctA126B.1.1770.000013
S452L452LctGctT1826B.1.3510.000535
S452L452LCtgTtg726B.1.3510.000208
S452L452LctGctA126B.1.3510.00003
S452L452LctGctT2121B.1.1.5190.000834
S452L452LctGctT1218B.1.1.2140.000665
S452L452LCtgTtg618B.1.1.2140.000333
S452L452LctGctT915B.1.5960.000784
S452L452LCtgTtg615B.1.5960.000523
S452L452LCtgTtg1313B.1.3110.003569
S452L452LctGctT1212B.1.177.730.006795
S452L452LctGctT1212B.1.2210.000852
S452L452LctGctA1011B.1.177.860.001835
S452L452LctGctT111B.1.177.860.000183
S452L452LctGctT711B.1.6210.00062
S452L452LCtgTtg411B.1.6210.000354
S452L452LCtgTtg1010B.1.1.3160.009251
S452L452LCtgTtg910B.1.2580.000599
S452L452LctGctT110B.1.2580.000067
S452L452LctGctT89B.1.1.3060.003507
S452L452LCtgTtg19B.1.1.3060.000438
S452L452LctGctT99B.1.3990.017408
S452L452LCtGTtA68AY.430.000027
S452L452LCtgTtg28AY.430.000009
S452L452LctGctT88B.1.177.750.008325
S452L452LctGctT77B.1.1.700.002387
S452L452LctGctT77B.1.5740.015054
S452L452LctGctT57B.1.5750.001517
S452L452LCtgTtg27B.1.5750.000607
S452L452LctGctT66B.1.1.2220.001224
S452L452LctGctT56P.1.150.001162
S452L452LCtgTtg16P.1.150.000232
S452L452LctGctT55A.10.001409
S452L452LctGctT55B.1.1.1280.035461
S452L452LctGctT55B.1.1.2840.000537
S452L452LctGctT55B.1.1.4330.007123
S452L452LctGctT55B.1.177.240.006477
S452L452LctGctT55B.1.4150.071429
S452L452LctGctT35B.1.5260.000071
S452L452LCtgTtg25B.1.5260.000047
S452L452LctGctT55P.1.170.000809
S452L452LctGctT55P.20.000933
S452L452LCtgTtg140.055556
S452L452LctGctA140.055556
S452L452LCtGTtA140.055556
S452L452LctGctT140.055556
S452L452LCtGTtA24B.1.1.10.000653
S452L452LctGctT24B.1.1.10.000653
S452L452LctGctT44B.1.1.2160.003562
S452L452LctGctT44B.1.177.400.020619
S452L452LctGctT34B.1.177.810.000568
S452L452LCtgTtg14B.1.177.810.000189
S452L452LctGctT44B.1.4060.024242
S452L452LctGctT34B.1.5090.002597
S452L452LCtgTtg14B.1.5090.000866
S452L452LCtGTtA24B.1.617.20.000008
S452L452LctGctC14B.1.617.20.000004
S452L452LctGctT14B.1.617.20.000004
S452L452LctGctT44Q.80.00066
S452L452LctGctT33B.1.1390.002199
S452L452LctGctT33B.1.177.70.000495
S452L452LctGctT33B.1.2430.000209
S452L452LctGctT33B.1.416.10.004687
S452L452LctGctT23Q.10.000253
S452L452LCtgTtg13Q.10.000126
S452L452LctGctT22B.1.110.30.001437
S452L452LctGctT22B.1.177.430.002954
S452L452LctGctT22B.1.2370.00995
S452L452LctGctT22B.1.2450.0625
S452L452LctGctT22B.1.360.000292
S452L452LctGctA22B.1.36.190.018519
S452L452LctGctT22B.1.36.220.002415
S452L452LctGctT22B.1.4000.000858
S452L452LctGctT22B.1.4620.014493
S452L452LctGctT22B.1.4690.00722
S452L452LctGctT22B.1.5950.000522
S452L452LctGctT22B.1.6250.004706
S452L452LCtgTtg22B.400.000729
S452L452LctGctA22B.6.60.001778
S452L452LctGctT22P.1.20.002312
S452L452LctGctT22P.1.80.009569
S452L452LctGctT22R.10.00018
S452L452LCtgTtg11A.20.000662
S452L452LctGctT11A.2.40.003367
S452L452LCtgTtg11AD.20.000219
S452L452LctGctT11AP.10.001502
S452L452LCtgTtg11AY.1060.000335
S452L452LCtGTtA11AY.1130.000142
S452L452LCtGTtA11AY.420.00004
S452L452LCtGTtA11AY.440.000006
S452L452LCtGTtA11AY.450.000122
S452L452LCtgTtg11AY.550.000917
S452L452LCtGTtA11AY.840.000437
S452L452LCtGTtA11AY.9.20.000037
S452L452LCtGTtA11AY.990.001049
S452L452LctGctT11AZ.30.00152
S452L452LctGctA11B0.000128
S452L452LctGctT11B.1.1.1480.008772
S452L452LctGctT11B.1.1.1640.005155
S452L452LctGctA11B.1.1.3170.000412
S452L452LctGctT11B.1.1.3180.000302
S452L452LctGctT11B.1.1.3280.016949
S452L452LctGctT11B.1.1.3480.000796
S452L452LCtgTtg11B.1.1.390.00051
S452L452LCtgTtg11B.1.1.3910.008547
S452L452LctGctT11B.1.1.3970.002252
S452L452LctGctA11B.1.1.4090.002833
S452L452LctGctT11B.1.1.4620.008621
S452L452LctGctT11B.1.1.5280.004808
S452L452LctGctT11B.1.1.590.006494
S452L452LctGctT11B.1.1.80.003584
S452L452LCtgTtg11B.1.1100.004525
S452L452LCtgTtg11B.1.1190.010526
S452L452LCtgTtg11B.1.1420.002899
S452L452LctGctT11B.1.1570.002985
S452L452LCtgTtg11B.1.160.260.002421
S452L452LctGctT11B.1.177.100.000878
S452L452LctGctT11B.1.177.180.00116
S452L452LctGctT11B.1.177.330.001645
S452L452LctGctT11B.1.177.40.000211
S452L452LctGctT11B.1.177.570.000281
S452L452LctGctT11B.1.177.840.006667
S452L452LctGctT11B.1.221.20.004016
S452L452LctGctT11B.1.2340.000132
S452L452LCtgTtg11B.1.2400.000216
S452L452LctGctT11B.1.258.170.000104
S452L452LctGctT11B.1.3050.002151
S452L452LctGctT11B.1.3290.000608
S452L452LctGctT11B.1.36.100.004785
S452L452LCtgTtg11B.1.36.180.00042
S452L452LctGctT11B.1.36.290.000517
S452L452LctGctT11B.1.36.80.001
S452L452LCtgTtg11B.1.3780.006849
S452L452LctGctT11B.1.3900.010638
S452L452LCtgTtg11B.1.3960.000706
S452L452LctGctT11B.1.3970.004854
S452L452LCtgTtg11B.1.4040.001302
S452L452LctGctT11B.1.4290.000024
S452L452LctGctT11B.1.5560.007519
S452L452LctGctT11B.1.5690.014493
S452L452LctGctT11B.1.619.10.000641
S452L452LctGctT11B.1.621.10.000506
S452L452LctGctT11B.570.015152
S452L452LctGctT11C.1.20.004255
S452L452LctGctT11C.350.000774
S452L452LctGctT11D.20.000075
S452L452LctGctT11N.50.001767
S452L452LctGctT11P.1.120.000484
S452L452LctGctT11P.1.70.000319
S452L452LctGctT11P.30.001595

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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