CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 417 | K417N | nonsyn | aaG | aaT | 45693 | 45671 | 0.999519 | 22811-22813 | |
S | 417 | K417N | nonsyn | aaG | aaC | 45693 | 22 | 0.000481474 | 22811-22813 |
Details of the mutation K417N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 417 | K417N | aaG | aaT | 45671 | 45693 | All | 0.008735 |
S | 417 | K417N | aaG | aaC | 22 | 45693 | All | 0.000004 |
S | 417 | K417N | aaG | aaT | 31424 | 31425 | B.1.351 | 0.934126 |
S | 417 | K417N | aaG | aaC | 1 | 31425 | B.1.351 | 0.00003 |
S | 417 | K417N | aaG | aaT | 3279 | 3279 | B.1.351.2 | 0.992133 |
S | 417 | K417N | aaG | aaT | 2808 | 2808 | AY.2 | 1 |
S | 417 | K417N | aaG | aaT | 2527 | 2527 | AY.1 | 1 |
S | 417 | K417N | aaG | aaT | 1662 | 1662 | B.1.351.5 | 0.996403 |
S | 417 | K417N | aaG | aaT | 1124 | 1124 | B.1.351.3 | 0.985101 |
S | 417 | K417N | aaG | aaT | 756 | 756 | B.1.621 | 0.06692 |
S | 417 | K417N | aaG | aaT | 360 | 362 | B.1.617.2 | 0.001356 |
S | 417 | K417N | aaG | aaC | 2 | 362 | B.1.617.2 | 0.000008 |
S | 417 | K417N | aaG | aaT | 341 | 341 | B.1 | 0.003123 |
S | 417 | K417N | aaG | aaT | 150 | 158 | B.1.1.7 | 0.000134 |
S | 417 | K417N | aaG | aaC | 8 | 158 | B.1.1.7 | 0.000007 |
S | 417 | K417N | aaG | aaT | 128 | 128 | B.1.554 | 0.563877 |
S | 417 | K417N | aaG | aaT | 105 | 105 | AY.103 | 0.000652 |
S | 417 | K417N | aaG | aaT | 97 | 98 | AY.25 | 0.000583 |
S | 417 | K417N | aaG | aaC | 1 | 98 | AY.25 | 0.000006 |
S | 417 | K417N | aaG | aaT | 79 | 79 | AY.44 | 0.000481 |
S | 417 | K417N | aaG | aaT | 51 | 51 | AY.43 | 0.000226 |
S | 417 | K417N | aaG | aaT | 51 | 51 | B.1.1 | 0.000925 |
S | 417 | K417N | aaG | aaT | 36 | 36 | AY.69 | 0.00672 |
S | 417 | K417N | aaG | aaT | 34 | 34 | B.1.170 | 0.146552 |
S | 417 | K417N | aaG | aaT | 28 | 28 | AY.56 | 0.044944 |
S | 417 | K417N | aaG | aaT | 25 | 25 | B.1.351.1 | 0.961538 |
S | 417 | K417N | aaG | aaT | 22 | 22 | AY.4 | 0.000034 |
S | 417 | K417N | aaG | aaT | 22 | 22 | AY.71 | 0.010451 |
S | 417 | K417N | aaG | aaT | 19 | 19 | AY.117 | 0.001606 |
S | 417 | K417N | aaG | aaT | 19 | 19 | AY.62 | 0.008279 |
S | 417 | K417N | aaG | aaT | 16 | 16 | AY.120 | 0.000595 |
S | 417 | K417N | aaG | aaT | 16 | 16 | B | 0.002045 |
S | 417 | K417N | aaG | aaT | 15 | 15 | AY.38 | 0.007489 |
S | 417 | K417N | aaG | aaT | 15 | 15 | AY.47 | 0.000467 |
S | 417 | K417N | aaG | aaT | 15 | 15 | AY.5 | 0.00031 |
S | 417 | K417N | aaG | aaT | 15 | 15 | B.1.429 | 0.000353 |
S | 417 | K417N | aaG | aaT | 14 | 14 | AY.26 | 0.000396 |
S | 417 | K417N | aaG | aaT | 13 | 13 | AY.39 | 0.000321 |
S | 417 | K417N | aaG | aaT | 13 | 13 | B.1.620 | 0.012299 |
S | 417 | K417N | aaG | aaT | 11 | 12 | AY.3 | 0.000109 |
S | 417 | K417N | aaG | aaC | 1 | 12 | AY.3 | 0.00001 |
S | 417 | K417N | aaG | aaT | 11 | 11 | B.1.177.73 | 0.006229 |
S | 417 | K417N | aaG | aaT | 11 | 11 | B.1.470 | 0.015449 |
S | 417 | K417N | aaG | aaT | 10 | 10 | AY.75 | 0.00056 |
S | 417 | K417N | aaG | aaT | 10 | 10 | AY.82 | 0.013569 |
S | 417 | K417N | aaG | aaT | 10 | 10 | B.1.636 | 0.067114 |
S | 417 | K417N | aaG | aaT | 9 | 9 | AY.20 | 0.00035 |
S | 417 | K417N | aaG | aaT | 8 | 9 | B.1.2 | 0.00007 |
S | 417 | K417N | aaG | aaC | 1 | 9 | B.1.2 | 0.000009 |
S | 417 | K417N | aaG | aaT | 8 | 8 | B.1.258 | 0.000532 |
S | 417 | K417N | aaG | aaT | 7 | 7 | AY.33 | 0.000467 |
S | 417 | K417N | aaG | aaT | 7 | 7 | B.1.595 | 0.001827 |
S | 417 | K417N | aaG | aaT | 6 | 6 | AY.119 | 0.000212 |
S | 417 | K417N | aaG | aaT | 6 | 6 | AY.23 | 0.000418 |
S | 417 | K417N | aaG | aaT | 6 | 6 | AY.37 | 0.001896 |
S | 417 | K417N | aaG | aaT | 6 | 6 | AY.65 | 0.003198 |
S | 417 | K417N | aaG | aaT | 6 | 6 | B.1.1.28 | 0.001867 |
S | 417 | K417N | aaG | aaT | 6 | 6 | B.1.177 | 0.000079 |
S | 417 | K417N | aaG | aaT | 6 | 6 | B.1.258.17 | 0.000624 |
S | 417 | K417N | aaG | aaT | 5 | 5 | AY.29 | 0.000079 |
S | 417 | K417N | aaG | aaT | 5 | 5 | AY.85 | 0.002136 |
S | 417 | K417N | aaG | aaT | 5 | 5 | B.1.1.389 | 0.030303 |
S | 417 | K417N | aaG | aaT | 5 | 5 | B.1.609 | 0.002397 |
S | 417 | K417N | aaG | aaT | 4 | 5 | B.1.637 | 0.000292 |
S | 417 | K417N | aaG | aaC | 1 | 5 | B.1.637 | 0.000073 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.102 | 0.000106 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.118 | 0.000251 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.16 | 0.001519 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.27 | 0.000259 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.4.5 | 0.00043 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.5.3 | 0.00135 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.52 | 0.003257 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.59 | 0.002119 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.61 | 0.000419 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.88 | 0.003537 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.92 | 0.001149 |
S | 417 | K417N | aaG | aaT | 4 | 4 | AY.98 | 0.000316 |
S | 417 | K417N | aaG | aaC | 4 | 4 | B.1.1.329 | 0.015385 |
S | 417 | K417N | aaG | aaT | 4 | 4 | B.1.1.432 | 0.005063 |
S | 417 | K417N | aaG | aaT | 4 | 4 | P.3 | 0.00638 |
S | 417 | K417N | aaG | aaT | 4 | 4 | P.5 | 0.054795 |
S | 417 | K417N | aaG | aaT | 3 | 3 | A | 0.001161 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.105 | 0.001929 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.106 | 0.001005 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.113 | 0.000427 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.116 | 0.00086 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.19 | 0.003421 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.34 | 0.000291 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.45 | 0.000365 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.54 | 0.000286 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.84 | 0.001312 |
S | 417 | K417N | aaG | aaT | 3 | 3 | AY.99 | 0.003148 |
S | 417 | K417N | aaG | aaT | 3 | 3 | B.1.1.306 | 0.001315 |
S | 417 | K417N | aaG | aaT | 3 | 3 | B.1.1.372 | 0.002066 |
S | 417 | K417N | aaG | aaT | 2 | 3 | B.1.526 | 0.000047 |
S | 417 | K417N | aaG | aaC | 1 | 3 | B.1.526 | 0.000024 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AU.2 | 0.004843 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.120.2.1 | 0.000997 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.121 | 0.000271 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.13 | 0.000322 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.42 | 0.00008 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.46.4 | 0.000329 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.5.4 | 0.000553 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.60 | 0.001876 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.63 | 0.000774 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.67 | 0.000929 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.7 | 0.000392 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.73 | 0.001331 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.79 | 0.002421 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.86 | 0.00166 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.94 | 0.000885 |
S | 417 | K417N | aaG | aaT | 2 | 2 | AY.99.2 | 0.000184 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.1.216 | 0.001781 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.1.222 | 0.000408 |
S | 417 | K417N | aaG | aaT | 1 | 2 | B.1.1.269 | 0.001353 |
S | 417 | K417N | aaG | aaC | 1 | 2 | B.1.1.269 | 0.001353 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.1.375 | 0.02381 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.177.52 | 0.003515 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.177.86 | 0.000367 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.221 | 0.000142 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.367 | 0.001585 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.596 | 0.000174 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.623 | 0.001073 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.626 | 0.011429 |
S | 417 | K417N | aaG | aaT | 2 | 2 | B.1.634 | 0.006849 |
S | 417 | K417N | aaG | aaT | 2 | 2 | Q.3 | 0.00029 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AT.1 | 0.005128 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.10 | 0.00053 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.108 | 0.001103 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.110 | 0.000113 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.114 | 0.000231 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.12 | 0.000316 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.120.1 | 0.000321 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.21 | 0.001898 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.22 | 0.002092 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.28 | 0.00189 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.32 | 0.000532 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.39.1 | 0.00004 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.4.3 | 0.000842 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.40 | 0.000964 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.41 | 0.000294 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.46 | 0.000104 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.51 | 0.000909 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.53 | 0.000288 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.55 | 0.000917 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.7.1 | 0.000113 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.75.1 | 0.00018 |
S | 417 | K417N | aaG | aaC | 1 | 1 | AY.77 | 0.001127 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.78 | 0.001541 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.87 | 0.000833 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.9 | 0.000068 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.9.2 | 0.000037 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.91 | 0.00073 |
S | 417 | K417N | aaG | aaT | 1 | 1 | AY.98.1 | 0.000048 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.1 | 0.000327 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.119 | 0.034483 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.203 | 0.016949 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.25 | 0.000569 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.277 | 0.000759 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.318 | 0.000302 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.354 | 0.004386 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.409 | 0.002833 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.422 | 0.045455 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.44 | 0.00241 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.519 | 0.00004 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.1.525 | 0.005464 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.177.31 | 0.011494 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.177.7 | 0.000165 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.179 | 0.003759 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.214.3 | 0.007143 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.279 | 0.000514 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.311 | 0.000275 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.320 | 0.001245 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.36.29 | 0.000517 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.375 | 0.00082 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.399 | 0.001934 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.427 | 0.00005 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.441 | 0.009615 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.524 | 0.001406 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.525 | 0.000113 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.599 | 0.00365 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.601 | 0.030303 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.617.3 | 0.002985 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.619 | 0.000871 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.621.1 | 0.000506 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.1.78 | 0.008547 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.27 | 0.015385 |
S | 417 | K417N | aaG | aaT | 1 | 1 | B.6 | 0.00091 |
S | 417 | K417N | aaG | aaT | 1 | 1 | C.16 | 0.00106 |
S | 417 | K417N | aaG | aaT | 1 | 1 | C.36.3 | 0.000567 |
S | 417 | K417N | aaG | aaT | 1 | 1 | C.37 | 0.000116 |
S | 417 | K417N | aaG | aaT | 1 | 1 | C.39 | 0.018868 |
S | 417 | K417N | aaG | aaT | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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