CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = K1045N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S1045K1045NnonsynaaGaaT5595570.99642224695-24697
S1045K1045NnonsynaaGaaC55920.0035778224695-24697

Details of the mutation K1045N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S1045K1045NaaGaaT557559All0.000107
S1045K1045NaaGaaC2559All0
S1045K1045NaaGaaT126126AY.40.000196
S1045K1045NaaGaaT9595B.1.177.380.989583
S1045K1045NaaGaaT5555B.1.1.70.000049
S1045K1045NaaGaaT2424AY.980.001896
S1045K1045NaaGaaT2121B.1.3510.000624
S1045K1045NaaGaaT1919AY.1020.000504
S1045K1045NaaGaaT1616B.1.5260.000376
S1045K1045NaaGaaT1516B.1.617.20.000056
S1045K1045NaaGaaC116B.1.617.20.000004
S1045K1045NaaGaaT1212AY.1030.000075
S1045K1045NaaGaaT1212B.1.4290.000282
S1045K1045NaaGaaT1010B.10.000092
S1045K1045NaaGaaT99B.1.20.000079
S1045K1045NaaGaaT88AY.250.000048
S1045K1045NaaGaaT88AY.440.000049
S1045K1045NaaGaaT66AY.50.000124
S1045K1045NaaGaaT66B.1.1.5190.000238
S1045K1045NaaGaaT55AY.1200.000186
S1045K1045NaaGaaT55AY.1210.000677
S1045K1045NaaGaaT55AY.390.000124
S1045K1045NaaGaaT55B.1.36.170.00247
S1045K1045NaaGaaT44AY.1190.000141
S1045K1045NaaGaaT44B.1.3490.002859
S1045K1045NaaGaaT33AY.260.000085
S1045K1045NaaGaaT33AY.360.000445
S1045K1045NaaGaaT33AY.4.20.000065
S1045K1045NaaGaaT33AY.470.000093
S1045K1045NaaGaaT33AY.600.002814
S1045K1045NaaGaaT33C.370.000348
S1045K1045NaaGaaT33P.10.000047
S1045K1045NaaGaaT22AY.1110.000366
S1045K1045NaaGaaT22AY.330.000134
S1045K1045NaaGaaT22AY.430.000009
S1045K1045NaaGaaT22AY.46.60.000144
S1045K1045NaaGaaT22AY.610.00021
S1045K1045NaaGaaT22AY.7.10.000225
S1045K1045NaaGaaT22AY.750.000112
S1045K1045NaaGaaT22AY.99.20.000184
S1045K1045NaaGaaT22B.1.10.000036
S1045K1045NaaGaaT22B.1.1600.000062
S1045K1045NaaGaaT22B.1.177.620.002384
S1045K1045NaaGaaT22B.1.2400.000431
S1045K1045NaaGaaC12B.1.2580.000067
S1045K1045NaaGaaT12B.1.2580.000067
S1045K1045NaaGaaT22B.1.5880.00182
S1045K1045NaaGaaT22B.1.617.10.000258
S1045K1045NaaGaaT110.055556
S1045K1045NaaGaaT11AT.10.005128
S1045K1045NaaGaaT11AY.10.000396
S1045K1045NaaGaaT11AY.1000.000046
S1045K1045NaaGaaT11AY.1090.00074
S1045K1045NaaGaaT11AY.1180.000063
S1045K1045NaaGaaT11AY.200.000039
S1045K1045NaaGaaT11AY.29.10.000221
S1045K1045NaaGaaT11AY.30.00001
S1045K1045NaaGaaT11AY.34.10.00051
S1045K1045NaaGaaT11AY.350.000233
S1045K1045NaaGaaT11AY.400.000964
S1045K1045NaaGaaT11AY.450.000122
S1045K1045NaaGaaT11AY.460.000104
S1045K1045NaaGaaT11AY.46.40.000165
S1045K1045NaaGaaT11AY.520.000814
S1045K1045NaaGaaT11AY.620.000436
S1045K1045NaaGaaT11AY.690.000187
S1045K1045NaaGaaT11AY.75.10.00018
S1045K1045NaaGaaT11AY.840.000437
S1045K1045NaaGaaT11AY.920.000287
S1045K1045NaaGaaT11B0.000128
S1045K1045NaaGaaT11B.1.1.2100.005714
S1045K1045NaaGaaT11B.1.1.280.000311
S1045K1045NaaGaaT11B.1.1.330.000421
S1045K1045NaaGaaT11B.1.1.4280.009434
S1045K1045NaaGaaT11B.1.1.4850.016667
S1045K1045NaaGaaT11B.1.1280.000635
S1045K1045NaaGaaT11B.1.1610.017241
S1045K1045NaaGaaT11B.1.177.150.000631
S1045K1045NaaGaaT11B.1.177.810.000189
S1045K1045NaaGaaT11B.1.1870.033333
S1045K1045NaaGaaT11B.1.3010.005917
S1045K1045NaaGaaT11B.1.360.000146
S1045K1045NaaGaaT11B.1.3670.000792
S1045K1045NaaGaaT11B.6.60.000889
S1045K1045NaaGaaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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