CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = I834I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	834	I834I		syn	atC	atT	731	695	0.950752	24062-24064
S	834	I834I		syn	atC	atA	731	36	0.0492476	24062-24064

Details of the mutation I834I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	834	I834I	atC	atT	695	731	All	0.000133
S	834	I834I	atC	atA	36	731	All	0.000007
S	834	I834I	atC	atT	137	141	B.1.617.2	0.000516
S	834	I834I	atC	atA	4	141	B.1.617.2	0.000015
S	834	I834I	atC	atT	96	96	AY.4	0.000149
S	834	I834I	atC	atT	68	78	B.1.1.7	0.000061
S	834	I834I	atC	atA	10	78	B.1.1.7	0.000009
S	834	I834I	atC	atT	69	69	B.1.243.2	1
S	834	I834I	atC	atT	48	48	AY.44	0.000292
S	834	I834I	atC	atT	37	37	B.1.177.54	0.022438
S	834	I834I	atC	atT	27	27	R.1	0.00243
S	834	I834I	atC	atT	24	24	AY.4.2	0.000521
S	834	I834I	atC	atT	12	18	B.1	0.00011
S	834	I834I	atC	atA	6	18	B.1	0.000055
S	834	I834I	atC	atT	16	16	AY.39	0.000395
S	834	I834I	atC	atT	10	11	AY.3	0.000099
S	834	I834I	atC	atA	1	11	AY.3	0.00001
S	834	I834I	atC	atT	11	11	B.1.438.1	0.00118
S	834	I834I	atC	atT	8	9	AY.43	0.000035
S	834	I834I	atC	atA	1	9	AY.43	0.000004
S	834	I834I	atC	atT	9	9	AY.92	0.002585
S	834	I834I	atC	atT	7	7	AY.23	0.000488
S	834	I834I	atC	atT	7	7	AY.5	0.000145
S	834	I834I	atC	atT	7	7	B.1.1	0.000127
S	834	I834I	atC	atT	7	7	B.1.243	0.000487
S	834	I834I	atC	atT	6	6	AY.45	0.00073
S	834	I834I	atC	atT	6	6	B.1.609	0.002876
S	834	I834I	atC	atT	5	5	AY.100	0.00023
S	834	I834I	atC	atT	5	5	AY.102	0.000133
S	834	I834I	atC	atT	4	5	AY.103	0.000025
S	834	I834I	atC	atA	1	5	AY.103	0.000006
S	834	I834I	atC	atT	5	5	AY.26	0.000142
S	834	I834I	atC	atT	5	5	B.1.389	0.00501
S	834	I834I	atC	atT	4	4	AY.46	0.000416
S	834	I834I	atC	atT	4	4	AY.64	0.002381
S	834	I834I	atC	atT	3	3	AY.120	0.000112
S	834	I834I	atC	atT	3	3	AY.40	0.002893
S	834	I834I	atC	atT	2	3	B.1.177	0.000026
S	834	I834I	atC	atA	1	3	B.1.177	0.000013
S	834	I834I	atC	atT	2	2	AY.117	0.000169
S	834	I834I	atC	atT	2	2	AY.33	0.000134
S	834	I834I	atC	atT	2	2	AY.47	0.000062
S	834	I834I	atC	atT	2	2	AY.67	0.000929
S	834	I834I	atC	atT	2	2	AY.75.1	0.000361
S	834	I834I	atC	atA	2	2	AY.9.2	0.000073
S	834	I834I	atC	atT	2	2	B.1.1.325	0.051282
S	834	I834I	atC	atA	2	2	B.1.2	0.000018
S	834	I834I	atC	atT	2	2	B.1.36	0.000292
S	834	I834I	atC	atA	2	2	B.6.6	0.001778
S	834	I834I	atC	atA	1	2	D.2	0.000075
S	834	I834I	atC	atT	1	2	D.2	0.000075
S	834	I834I	atC	atT	2	2	P.1	0.000032
S	834	I834I	atC	atT	1	1		0.055556
S	834	I834I	atC	atT	1	1	A.27	0.001656
S	834	I834I	atC	atT	1	1	AY.106	0.000335
S	834	I834I	atC	atT	1	1	AY.107	0.000466
S	834	I834I	atC	atA	1	1	AY.16.1	0.00047
S	834	I834I	atC	atA	1	1	AY.20	0.000039
S	834	I834I	atC	atA	1	1	AY.24	0.000431
S	834	I834I	atC	atA	1	1	AY.25	0.000006
S	834	I834I	atC	atT	1	1	AY.29	0.000016
S	834	I834I	atC	atT	1	1	AY.34	0.000097
S	834	I834I	atC	atT	1	1	AY.4.5	0.000107
S	834	I834I	atC	atT	1	1	AY.46.6	0.000072
S	834	I834I	atC	atT	1	1	AY.7	0.000196
S	834	I834I	atC	atT	1	1	AY.70	0.000209
S	834	I834I	atC	atT	1	1	AY.96	0.002075
S	834	I834I	atC	atT	1	1	AY.99	0.001049
S	834	I834I	atC	atT	1	1	B.1.1.203	0.016949
S	834	I834I	atC	atT	1	1	B.1.1.267	0.010101
S	834	I834I	atC	atT	1	1	B.1.1.348	0.000796
S	834	I834I	atC	atT	1	1	B.1.160	0.000031
S	834	I834I	atC	atT	1	1	B.1.177.21	0.000076
S	834	I834I	atC	atT	1	1	B.1.177.33	0.001645
S	834	I834I	atC	atT	1	1	B.1.240	0.000216
S	834	I834I	atC	atT	1	1	B.1.258	0.000067
S	834	I834I	atC	atA	1	1	B.1.301	0.005917
S	834	I834I	atC	atT	1	1	B.1.349	0.000715
S	834	I834I	atC	atT	1	1	B.1.429	0.000024
S	834	I834I	atC	atT	1	1	B.1.526	0.000024
S	834	I834I	atC	atT	1	1	B.1.561	0.000397
S	834	I834I	atC	atT	1	1	B.3	0.000831
S	834	I834I	atC	atT	1	1	P.1.7	0.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.