CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = H245Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	245	H245Y		nonsyn	Cat	Tat	5124	5124	1	22295-22297

Details of the mutation H245Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	245	H245Y	Cat	Tat	5124	5124	All	0.00098
S	245	H245Y	Cat	Tat	1368	1368	B.1.1.7	0.001225
S	245	H245Y	Cat	Tat	956	956	B.1.620	0.904447
S	245	H245Y	Cat	Tat	366	366	B.1.289	0.973404
S	245	H245Y	Cat	Tat	316	316	AY.3	0.003143
S	245	H245Y	Cat	Tat	207	207	B.1.617.2	0.000779
S	245	H245Y	Cat	Tat	186	186	AY.4	0.000289
S	245	H245Y	Cat	Tat	132	132	AY.103	0.00082
S	245	H245Y	Cat	Tat	112	112	B.1.177	0.001475
S	245	H245Y	Cat	Tat	106	106	AY.98.1	0.005134
S	245	H245Y	Cat	Tat	106	106	B.1	0.000971
S	245	H245Y	Cat	Tat	99	99	AY.43	0.000439
S	245	H245Y	Cat	Tat	78	78	B.1.351	0.002319
S	245	H245Y	Cat	Tat	66	66	Q.2	0.040491
S	245	H245Y	Cat	Tat	52	52	AY.44	0.000317
S	245	H245Y	Cat	Tat	51	51	B.1.2	0.000449
S	245	H245Y	Cat	Tat	50	50	AY.118	0.003132
S	245	H245Y	Cat	Tat	44	44	AY.5	0.000909
S	245	H245Y	Cat	Tat	33	33	B.1.1	0.000599
S	245	H245Y	Cat	Tat	32	32	AY.25	0.000192
S	245	H245Y	Cat	Tat	29	29	B.1.1.284	0.003115
S	245	H245Y	Cat	Tat	27	27	B.1.427	0.001363
S	245	H245Y	Cat	Tat	24	24	AY.119	0.000847
S	245	H245Y	Cat	Tat	21	21	AY.102	0.000557
S	245	H245Y	Cat	Tat	21	21	AY.39	0.000519
S	245	H245Y	Cat	Tat	20	20	AY.6	0.000823
S	245	H245Y	Cat	Tat	19	19	P.1.17	0.003073
S	245	H245Y	Cat	Tat	17	17	P.1	0.000268
S	245	H245Y	Cat	Tat	16	16	AY.39.1	0.000634
S	245	H245Y	Cat	Tat	16	16	AY.4.2	0.000347
S	245	H245Y	Cat	Tat	16	16	AY.42	0.000644
S	245	H245Y	Cat	Tat	16	16	Q.1	0.002021
S	245	H245Y	Cat	Tat	15	15	AY.46	0.001561
S	245	H245Y	Cat	Tat	15	15	B.1.369	0.004278
S	245	H245Y	Cat	Tat	14	14	AY.29	0.000221
S	245	H245Y	Cat	Tat	13	13	B.1.160	0.000405
S	245	H245Y	Cat	Tat	12	12	B.1.258	0.000799
S	245	H245Y	Cat	Tat	11	11	AY.14	0.000968
S	245	H245Y	Cat	Tat	11	11	B.1.177.81	0.002083
S	245	H245Y	Cat	Tat	11	11	B.1.429	0.000259
S	245	H245Y	Cat	Tat	10	10	AY.26	0.000283
S	245	H245Y	Cat	Tat	9	9	AY.61	0.000943
S	245	H245Y	Cat	Tat	8	8	AY.5.3	0.002699
S	245	H245Y	Cat	Tat	8	8	B.1.1.70	0.002729
S	245	H245Y	Cat	Tat	8	8	B.1.243	0.000557
S	245	H245Y	Cat	Tat	8	8	B.1.526	0.000188
S	245	H245Y	Cat	Tat	8	8	B.1.637	0.000585
S	245	H245Y	Cat	Tat	8	8	Q.4	0.003638
S	245	H245Y	Cat	Tat	7	7	AY.20	0.000272
S	245	H245Y	Cat	Tat	7	7	AY.34	0.000679
S	245	H245Y	Cat	Tat	7	7	AY.47	0.000218
S	245	H245Y	Cat	Tat	7	7	B.1.1.28	0.002179
S	245	H245Y	Cat	Tat	6	6	AY.100	0.000276
S	245	H245Y	Cat	Tat	6	6	B.1.177.4	0.001266
S	245	H245Y	Cat	Tat	6	6	B.1.221	0.000426
S	245	H245Y	Cat	Tat	6	6	B.1.564	0.002555
S	245	H245Y	Cat	Tat	6	6	B.1.596	0.000523
S	245	H245Y	Cat	Tat	6	6	B.1.617.1	0.000774
S	245	H245Y	Cat	Tat	6	6	D.2	0.00045
S	245	H245Y	Cat	Tat	6	6	P.1.14	0.000287
S	245	H245Y	Cat	Tat	5	5	AY.33	0.000334
S	245	H245Y	Cat	Tat	5	5	AY.9.2	0.000184
S	245	H245Y	Cat	Tat	5	5	B	0.000639
S	245	H245Y	Cat	Tat	5	5	B.1.240	0.001078
S	245	H245Y	Cat	Tat	5	5	B.1.438.1	0.000536
S	245	H245Y	Cat	Tat	4	4	AY.116.1	0.001246
S	245	H245Y	Cat	Tat	4	4	AY.117	0.000338
S	245	H245Y	Cat	Tat	4	4	AY.27	0.000259
S	245	H245Y	Cat	Tat	4	4	AY.30	0.001583
S	245	H245Y	Cat	Tat	4	4	AY.35	0.000932
S	245	H245Y	Cat	Tat	4	4	AY.75	0.000224
S	245	H245Y	Cat	Tat	4	4	B.1.36	0.000584
S	245	H245Y	Cat	Tat	4	4	C.36.3	0.002269
S	245	H245Y	Cat	Tat	3	3	AY.106	0.001005
S	245	H245Y	Cat	Tat	3	3	AY.120	0.000112
S	245	H245Y	Cat	Tat	3	3	AY.23	0.000209
S	245	H245Y	Cat	Tat	3	3	AY.54	0.000286
S	245	H245Y	Cat	Tat	3	3	AY.93	0.000819
S	245	H245Y	Cat	Tat	3	3	AZ.2	0.002463
S	245	H245Y	Cat	Tat	3	3	B.1.1.33	0.001263
S	245	H245Y	Cat	Tat	3	3	B.1.1.519	0.000119
S	245	H245Y	Cat	Tat	3	3	B.1.177.21	0.000229
S	245	H245Y	Cat	Tat	3	3	B.1.177.60	0.000655
S	245	H245Y	Cat	Tat	3	3	B.1.234	0.000396
S	245	H245Y	Cat	Tat	3	3	B.1.239	0.003663
S	245	H245Y	Cat	Tat	3	3	B.1.298	0.006342
S	245	H245Y	Cat	Tat	3	3	B.1.349	0.002144
S	245	H245Y	Cat	Tat	3	3	B.1.36.18	0.001261
S	245	H245Y	Cat	Tat	3	3	B.1.595	0.000783
S	245	H245Y	Cat	Tat	3	3	B.1.621	0.000266
S	245	H245Y	Cat	Tat	3	3	C.16	0.003181
S	245	H245Y	Cat	Tat	3	3	P.1.16	0.001122
S	245	H245Y	Cat	Tat	2	2	AY.101	0.000981
S	245	H245Y	Cat	Tat	2	2	AY.105	0.001286
S	245	H245Y	Cat	Tat	2	2	AY.116	0.000574
S	245	H245Y	Cat	Tat	2	2	AY.12	0.000632
S	245	H245Y	Cat	Tat	2	2	AY.121	0.000271
S	245	H245Y	Cat	Tat	2	2	AY.13	0.000322
S	245	H245Y	Cat	Tat	2	2	AY.36	0.000296
S	245	H245Y	Cat	Tat	2	2	AY.4.2.1	0.000298
S	245	H245Y	Cat	Tat	2	2	AY.4.5	0.000215
S	245	H245Y	Cat	Tat	2	2	AY.41	0.000588
S	245	H245Y	Cat	Tat	2	2	AY.5.4	0.000553
S	245	H245Y	Cat	Tat	2	2	AY.53	0.000575
S	245	H245Y	Cat	Tat	2	2	AY.75.1	0.000361
S	245	H245Y	Cat	Tat	2	2	AY.84	0.000875
S	245	H245Y	Cat	Tat	2	2	AY.9	0.000135
S	245	H245Y	Cat	Tat	2	2	AY.92	0.000575
S	245	H245Y	Cat	Tat	2	2	B.1.1.214	0.000111
S	245	H245Y	Cat	Tat	2	2	B.1.1.298	0.001724
S	245	H245Y	Cat	Tat	2	2	B.1.1.37	0.000386
S	245	H245Y	Cat	Tat	2	2	B.1.232	0.001075
S	245	H245Y	Cat	Tat	2	2	B.1.311	0.000549
S	245	H245Y	Cat	Tat	2	2	B.1.36.28	0.011494
S	245	H245Y	Cat	Tat	2	2	B.1.36.7	0.008
S	245	H245Y	Cat	Tat	2	2	B.1.426	0.002018
S	245	H245Y	Cat	Tat	2	2	B.1.499	0.002101
S	245	H245Y	Cat	Tat	2	2	B.1.515	0.028986
S	245	H245Y	Cat	Tat	2	2	B.1.561	0.000794
S	245	H245Y	Cat	Tat	2	2	B.1.619	0.001742
S	245	H245Y	Cat	Tat	2	2	B.40	0.000729
S	245	H245Y	Cat	Tat	2	2	C.37	0.000232
S	245	H245Y	Cat	Tat	2	2	P.1.12	0.000968
S	245	H245Y	Cat	Tat	2	2	Q.3	0.00029
S	245	H245Y	Cat	Tat	1	1	A	0.000387
S	245	H245Y	Cat	Tat	1	1	A.23.1	0.000704
S	245	H245Y	Cat	Tat	1	1	AY.1	0.000396
S	245	H245Y	Cat	Tat	1	1	AY.10	0.00053
S	245	H245Y	Cat	Tat	1	1	AY.110	0.000113
S	245	H245Y	Cat	Tat	1	1	AY.113	0.000142
S	245	H245Y	Cat	Tat	1	1	AY.114	0.000231
S	245	H245Y	Cat	Tat	1	1	AY.15	0.002222
S	245	H245Y	Cat	Tat	1	1	AY.16	0.00038
S	245	H245Y	Cat	Tat	1	1	AY.16.1	0.00047
S	245	H245Y	Cat	Tat	1	1	AY.2	0.000356
S	245	H245Y	Cat	Tat	1	1	AY.3.1	0.000085
S	245	H245Y	Cat	Tat	1	1	AY.37	0.000316
S	245	H245Y	Cat	Tat	1	1	AY.38	0.000499
S	245	H245Y	Cat	Tat	1	1	AY.45	0.000122
S	245	H245Y	Cat	Tat	1	1	AY.46.2	0.000635
S	245	H245Y	Cat	Tat	1	1	AY.46.6	0.000072
S	245	H245Y	Cat	Tat	1	1	AY.52	0.000814
S	245	H245Y	Cat	Tat	1	1	AY.55	0.000917
S	245	H245Y	Cat	Tat	1	1	AY.58	0.000907
S	245	H245Y	Cat	Tat	1	1	AY.60	0.000938
S	245	H245Y	Cat	Tat	1	1	AY.65	0.000533
S	245	H245Y	Cat	Tat	1	1	AY.7	0.000196
S	245	H245Y	Cat	Tat	1	1	AY.7.1	0.000113
S	245	H245Y	Cat	Tat	1	1	AY.70	0.000209
S	245	H245Y	Cat	Tat	1	1	AY.71	0.000475
S	245	H245Y	Cat	Tat	1	1	AY.8	0.000606
S	245	H245Y	Cat	Tat	1	1	AY.87	0.000833
S	245	H245Y	Cat	Tat	1	1	AY.9.1	0.000084
S	245	H245Y	Cat	Tat	1	1	AY.91	0.00073
S	245	H245Y	Cat	Tat	1	1	AY.98	0.000079
S	245	H245Y	Cat	Tat	1	1	AY.99.2	0.000092
S	245	H245Y	Cat	Tat	1	1	AZ.5	0.003509
S	245	H245Y	Cat	Tat	1	1	B.1.1.129	0.009174
S	245	H245Y	Cat	Tat	1	1	B.1.1.187	0.00885
S	245	H245Y	Cat	Tat	1	1	B.1.1.216	0.00089
S	245	H245Y	Cat	Tat	1	1	B.1.1.25	0.000569
S	245	H245Y	Cat	Tat	1	1	B.1.1.286	0.002899
S	245	H245Y	Cat	Tat	1	1	B.1.1.308	0.011765
S	245	H245Y	Cat	Tat	1	1	B.1.1.311	0.000358
S	245	H245Y	Cat	Tat	1	1	B.1.1.315	0.008475
S	245	H245Y	Cat	Tat	1	1	B.1.1.317	0.000412
S	245	H245Y	Cat	Tat	1	1	B.1.1.326	0.001761
S	245	H245Y	Cat	Tat	1	1	B.1.1.349	0.010309
S	245	H245Y	Cat	Tat	1	1	B.1.1.369	0.000446
S	245	H245Y	Cat	Tat	1	1	B.1.1.374	0.002375
S	245	H245Y	Cat	Tat	1	1	B.1.1.377	0.001381
S	245	H245Y	Cat	Tat	1	1	B.1.1.434	0.000349
S	245	H245Y	Cat	Tat	1	1	B.1.1.61	0.008772
S	245	H245Y	Cat	Tat	1	1	B.1.1.63	0.000386
S	245	H245Y	Cat	Tat	1	1	B.1.108	0.005814
S	245	H245Y	Cat	Tat	1	1	B.1.128	0.000635
S	245	H245Y	Cat	Tat	1	1	B.1.139	0.000733
S	245	H245Y	Cat	Tat	1	1	B.1.160.14	0.002119
S	245	H245Y	Cat	Tat	1	1	B.1.173	0.026316
S	245	H245Y	Cat	Tat	1	1	B.1.177.10	0.000878
S	245	H245Y	Cat	Tat	1	1	B.1.177.11	0.001698
S	245	H245Y	Cat	Tat	1	1	B.1.177.44	0.000519
S	245	H245Y	Cat	Tat	1	1	B.1.177.46	0.000918
S	245	H245Y	Cat	Tat	1	1	B.1.177.54	0.000606
S	245	H245Y	Cat	Tat	1	1	B.1.177.56	0.000668
S	245	H245Y	Cat	Tat	1	1	B.1.177.57	0.000281
S	245	H245Y	Cat	Tat	1	1	B.1.177.65	0.000665
S	245	H245Y	Cat	Tat	1	1	B.1.177.79	0.002342
S	245	H245Y	Cat	Tat	1	1	B.1.177.8	0.000752
S	245	H245Y	Cat	Tat	1	1	B.1.177.86	0.000183
S	245	H245Y	Cat	Tat	1	1	B.1.258.11	0.000396
S	245	H245Y	Cat	Tat	1	1	B.1.258.17	0.000104
S	245	H245Y	Cat	Tat	1	1	B.1.36.1	0.00114
S	245	H245Y	Cat	Tat	1	1	B.1.36.21	0.00216
S	245	H245Y	Cat	Tat	1	1	B.1.36.36	0.000602
S	245	H245Y	Cat	Tat	1	1	B.1.385	0.010638
S	245	H245Y	Cat	Tat	1	1	B.1.389	0.001002
S	245	H245Y	Cat	Tat	1	1	B.1.396	0.000706
S	245	H245Y	Cat	Tat	1	1	B.1.413	0.004255
S	245	H245Y	Cat	Tat	1	1	B.1.471	0.002732
S	245	H245Y	Cat	Tat	1	1	B.1.497	0.000315
S	245	H245Y	Cat	Tat	1	1	B.1.516	0.001957
S	245	H245Y	Cat	Tat	1	1	B.1.524	0.001406
S	245	H245Y	Cat	Tat	1	1	B.1.525	0.000113
S	245	H245Y	Cat	Tat	1	1	B.1.565	0.00081
S	245	H245Y	Cat	Tat	1	1	B.1.576	0.000907
S	245	H245Y	Cat	Tat	1	1	B.1.601	0.030303
S	245	H245Y	Cat	Tat	1	1	B.1.619.1	0.000641
S	245	H245Y	Cat	Tat	1	1	B.1.625	0.002353
S	245	H245Y	Cat	Tat	1	1	B.1.628	0.000352
S	245	H245Y	Cat	Tat	1	1	B.28	0.003279
S	245	H245Y	Cat	Tat	1	1	B.29	0.003509
S	245	H245Y	Cat	Tat	1	1	B.47	0.020408
S	245	H245Y	Cat	Tat	1	1	B.6.6	0.000889
S	245	H245Y	Cat	Tat	1	1	L.3	0.003546
S	245	H245Y	Cat	Tat	1	1	N.5	0.001767
S	245	H245Y	Cat	Tat	1	1	P.1.1	0.000318
S	245	H245Y	Cat	Tat	1	1	P.1.10	0.000269
S	245	H245Y	Cat	Tat	1	1	P.1.6	0.001946
S	245	H245Y	Cat	Tat	1	1	P.1.7	0.000319
S	245	H245Y	Cat	Tat	1	1	P.2	0.000187
S	245	H245Y	Cat	Tat	1	1	Q.8	0.000165
S	245	H245Y	Cat	Tat	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.