CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = F490S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S490F490SnonsyntTttCt14547145450.99986223030-23032
S490F490SnonsyntTTtCA1454710.000068742723030-23032
S490F490SnonsyntTTtCG1454710.000068742723030-23032

Details of the mutation F490S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S490F490StTttCt1454514547All0.002782
S490F490StTTtCG114547All0
S490F490StTTtCA114547All0
S490F490StTttCt84148415C.370.976555
S490F490StTTtCG18415C.370.000116
S490F490StTttCt41794180B.1.1.70.003741
S490F490StTTtCA14180B.1.1.70.000001
S490F490StTttCt368368C.37.10.963351
S490F490StTttCt172172B.1.6260.982857
S490F490StTttCt145145AY.40.000226
S490F490StTttCt136136Q.30.019724
S490F490StTttCt126126B.1.617.20.000474
S490F490StTttCt7878P.1.150.018123
S490F490StTttCt7777B.1.10.001397
S490F490StTttCt7272AY.1030.000447
S490F490StTttCt7070A.210.193906
S490F490StTttCt6464B.10.000586
S490F490StTttCt5252B.1.20.000458
S490F490StTttCt4141Q.50.694915
S490F490StTttCt2424AY.440.000146
S490F490StTttCt2121AY.430.000093
S490F490StTttCt2020AY.330.001336
S490F490StTttCt2020B.1.1770.000263
S490F490StTttCt1515AY.1020.000398
S490F490StTttCt1515AY.260.000425
S490F490StTttCt1515B.1.1.2940.018987
S490F490StTttCt1313B.1.1.5280.0625
S490F490StTttCt1212B.1.1.4560.666667
S490F490StTttCt1111AY.1000.000506
S490F490StTttCt1111B.1.1600.000343
S490F490StTttCt1111B.1.2210.000781
S490F490StTttCt1111P.1.10.003494
S490F490StTttCt1010B.1.1.1760.004394
S490F490StTttCt1010B.1.1.5190.000397
S490F490StTttCt1010B.1.2580.000665
S490F490StTttCt1010B.1.5640.004259
S490F490StTttCt1010P.1.120.00484
S490F490StTttCt99AY.30.00009
S490F490StTttCt99AY.390.000222
S490F490StTttCt99AY.540.000858
S490F490StTttCt99B.1.1.280.002801
S490F490StTttCt88AY.200.000311
S490F490StTttCt88B.1.1.3720.00551
S490F490StTttCt88P.10.000126
S490F490StTttCt77AY.250.000042
S490F490StTttCt77AY.450.000852
S490F490StTttCt77AY.560.011236
S490F490StTttCt77B.1.4290.000165
S490F490StTttCt66B.1.1.3480.004777
S490F490StTttCt66B.1.2430.000418
S490F490StTttCt66Q.10.000758
S490F490StTttCt55B.1.1.330.002104
S490F490StTttCt55B.1.3510.000149
S490F490StTttCt55B.1.4270.000252
S490F490StTttCt55B.280.016393
S490F490StTttCt44AY.230.000279
S490F490StTttCt44AY.880.003537
S490F490StTttCt44B.1.1.1610.014134
S490F490StTttCt44B.1.1.4640.005891
S490F490StTttCt44B.1.214.20.002398
S490F490StTttCt44B.1.360.000584
S490F490StTttCt44B.1.36.290.002069
S490F490StTttCt44B.1.5260.000094
S490F490StTttCt44C.390.075472
S490F490StTttCt33AY.1200.000112
S490F490StTttCt33AY.3.10.000256
S490F490StTttCt33AY.4.20.000065
S490F490StTttCt33AY.480.001395
S490F490StTttCt33AY.980.000237
S490F490StTttCt33AY.98.10.000145
S490F490StTttCt33B.1.177.210.000229
S490F490StTttCt33R.10.00027
S490F490StTttCt22AY.1100.000225
S490F490StTttCt22AY.1160.000574
S490F490StTttCt22AY.1170.000169
S490F490StTttCt22AY.160.000759
S490F490StTttCt22AY.750.000112
S490F490StTttCt22AY.75.10.000361
S490F490StTttCt22AY.900.001369
S490F490StTttCt22B.1.1.10.000653
S490F490StTttCt22B.1.1.2320.00363
S490F490StTttCt22B.1.1.4090.005666
S490F490StTttCt22B.1.1040.00738
S490F490StTttCt22B.1.110.30.001437
S490F490StTttCt22B.1.2390.002442
S490F490StTttCt22B.1.3250.013793
S490F490StTttCt22B.1.5210.00995
S490F490StTttCt22B.1.564.10.003155
S490F490StTttCt22B.1.5960.000174
S490F490StTttCt22B.1.6370.000146
S490F490StTttCt22B.60.00182
S490F490StTttCt22N.60.014184
S490F490StTttCt22P.1.10.10.01626
S490F490StTttCt22P.1.160.000748
S490F490StTttCt22Q.80.00033
S490F490StTttCt22W.40.002703
S490F490StTttCt11A0.000387
S490F490StTttCt11A.190.009434
S490F490StTttCt11A.23.10.000704
S490F490StTttCt11AD.20.000219
S490F490StTttCt11AE.80.000489
S490F490StTttCt11AY.1060.000335
S490F490StTttCt11AY.1210.000135
S490F490StTttCt11AY.140.000088
S490F490StTttCt11AY.240.000431
S490F490StTttCt11AY.290.000016
S490F490StTttCt11AY.320.000532
S490F490StTttCt11AY.340.000097
S490F490StTttCt11AY.350.000233
S490F490StTttCt11AY.360.000148
S490F490StTttCt11AY.420.00004
S490F490StTttCt11AY.46.40.000165
S490F490StTttCt11AY.520.000814
S490F490StTttCt11AY.580.000907
S490F490StTttCt11AY.60.000041
S490F490StTttCt11AY.670.000464
S490F490StTttCt11AY.680.000274
S490F490StTttCt11AY.840.000437
S490F490StTttCt11AY.850.000427
S490F490StTttCt11AY.9.20.000037
S490F490StTttCt11AY.930.000273
S490F490StTttCt11AY.99.20.000092
S490F490StTttCt11B0.000128
S490F490StTttCt11B.1.1.1210.002427
S490F490StTttCt11B.1.1.1890.001513
S490F490StTttCt11B.1.1.2140.000055
S490F490StTttCt11B.1.1.2730.006757
S490F490StTttCt11B.1.1.2840.000107
S490F490StTttCt11B.1.1.3110.000358
S490F490StTttCt11B.1.1.3540.004386
S490F490StTttCt11B.1.1.3620.005618
S490F490StTttCt11B.1.1.370.000193
S490F490StTttCt11B.1.1.390.00051
S490F490StTttCt11B.1.1.4120.007634
S490F490StTttCt11B.1.1.4160.000905
S490F490StTttCt11B.1.1.4330.001425
S490F490StTttCt11B.1.1.630.000386
S490F490StTttCt11B.1.1340.005464
S490F490StTttCt11B.1.177.860.000183
S490F490StTttCt11B.1.2100.002132
S490F490StTttCt11B.1.2250.015385
S490F490StTttCt11B.1.2360.002053
S490F490StTttCt11B.1.3110.000275
S490F490StTttCt11B.1.3240.001605
S490F490StTttCt11B.1.36.170.000494
S490F490StTttCt11B.1.3960.000706
S490F490StTttCt11B.1.4510.008197
S490F490StTttCt11B.1.4700.001404
S490F490StTttCt11B.1.4800.002488
S490F490StTttCt11B.1.5170.000427
S490F490StTttCt11B.1.5750.000303
S490F490StTttCt11B.1.5770.000687
S490F490StTttCt11B.1.5910.010638
S490F490StTttCt11B.1.6280.000352
S490F490StTttCt11B.230.002924
S490F490StTttCt11C.140.004329
S490F490StTttCt11C.350.000774
S490F490StTttCt11C.36.3.10.002717
S490F490StTttCt11C.60.037037
S490F490StTttCt11D.30.005917
S490F490StTttCt11N.50.001767
S490F490StTttCt11P.1.100.000269
S490F490StTttCt11P.1.130.000898
S490F490StTttCt11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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