CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = E484Q

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	484	E484Q		nonsyn	Gaa	Caa	13561	13561	1	23012-23014

Details of the mutation E484Q within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	484	E484Q	Gaa	Caa	13561	13561	All	0.002594
S	484	E484Q	Gaa	Caa	7288	7288	B.1.617.1	0.939902
S	484	E484Q	Gaa	Caa	1221	1221	AY.35	0.284549
S	484	E484Q	Gaa	Caa	614	614	AY.36	0.091003
S	484	E484Q	Gaa	Caa	602	602	AY.4	0.000937
S	484	E484Q	Gaa	Caa	600	600	B.1.617.2	0.002259
S	484	E484Q	Gaa	Caa	398	398	B.1.1.7	0.000356
S	484	E484Q	Gaa	Caa	310	310	B.1.617.3	0.925373
S	484	E484Q	Gaa	Caa	184	184	B.1.630	0.963351
S	484	E484Q	Gaa	Caa	152	152	AY.103	0.000944
S	484	E484Q	Gaa	Caa	144	144	AY.100	0.006625
S	484	E484Q	Gaa	Caa	142	142	AY.102	0.003765
S	484	E484Q	Gaa	Caa	132	132	B.1.1	0.002395
S	484	E484Q	Gaa	Caa	116	116	AY.9.2	0.004261
S	484	E484Q	Gaa	Caa	116	116	B.1.628	0.040874
S	484	E484Q	Gaa	Caa	107	107	B.1	0.00098
S	484	E484Q	Gaa	Caa	97	97	AY.26	0.002746
S	484	E484Q	Gaa	Caa	88	88	AY.43	0.00039
S	484	E484Q	Gaa	Caa	73	73	AY.44	0.000444
S	484	E484Q	Gaa	Caa	61	61	P.5	0.835616
S	484	E484Q	Gaa	Caa	58	58	AY.25	0.000349
S	484	E484Q	Gaa	Caa	49	49	B.1.2	0.000431
S	484	E484Q	Gaa	Caa	46	46	AY.33	0.003072
S	484	E484Q	Gaa	Caa	45	45	AY.108	0.049614
S	484	E484Q	Gaa	Caa	35	35	AY.5	0.000723
S	484	E484Q	Gaa	Caa	35	35	AY.70	0.007298
S	484	E484Q	Gaa	Caa	32	32	AY.113	0.004556
S	484	E484Q	Gaa	Caa	26	26	AY.45	0.003164
S	484	E484Q	Gaa	Caa	24	24	AY.120.1	0.007705
S	484	E484Q	Gaa	Caa	24	24	AY.99.2	0.002212
S	484	E484Q	Gaa	Caa	24	24	B.1.177	0.000316
S	484	E484Q	Gaa	Caa	22	22	AY.75	0.001232
S	484	E484Q	Gaa	Caa	21	21	AY.23	0.001465
S	484	E484Q	Gaa	Caa	21	21	AY.39	0.000519
S	484	E484Q	Gaa	Caa	19	19	B.1.637	0.001388
S	484	E484Q	Gaa	Caa	18	18	AY.20	0.0007
S	484	E484Q	Gaa	Caa	18	18	AY.9.1	0.001507
S	484	E484Q	Gaa	Caa	17	17	B.1.596	0.001481
S	484	E484Q	Gaa	Caa	16	16	AY.120	0.000595
S	484	E484Q	Gaa	Caa	16	16	AY.121	0.002165
S	484	E484Q	Gaa	Caa	14	14	AY.1	0.00554
S	484	E484Q	Gaa	Caa	14	14	AY.119	0.000494
S	484	E484Q	Gaa	Caa	14	14	B.1.177.5	0.017391
S	484	E484Q	Gaa	Caa	13	13	AY.3.1	0.001108
S	484	E484Q	Gaa	Caa	12	12	AY.117	0.001014
S	484	E484Q	Gaa	Caa	12	12	B.1.1.29	0.123711
S	484	E484Q	Gaa	Caa	12	12	B.1.214	0.043956
S	484	E484Q	Gaa	Caa	11	11	B.1.177.18	0.012761
S	484	E484Q	Gaa	Caa	11	11	B.1.429	0.000259
S	484	E484Q	Gaa	Caa	10	10	AY.46.6	0.000722
S	484	E484Q	Gaa	Caa	10	10	AY.52	0.008143
S	484	E484Q	Gaa	Caa	10	10	AY.61	0.001048
S	484	E484Q	Gaa	Caa	10	10	B.1.243	0.000696
S	484	E484Q	Gaa	Caa	9	9	AY.46	0.000937
S	484	E484Q	Gaa	Caa	9	9	AY.77	0.010147
S	484	E484Q	Gaa	Caa	9	9	B.1.1.1	0.00294
S	484	E484Q	Gaa	Caa	9	9	B.1.221	0.000639
S	484	E484Q	Gaa	Caa	9	9	L.3	0.031915
S	484	E484Q	Gaa	Caa	8	8	AY.29	0.000126
S	484	E484Q	Gaa	Caa	8	8	AY.76	0.038647
S	484	E484Q	Gaa	Caa	8	8	B.1.179	0.030075
S	484	E484Q	Gaa	Caa	8	8	B.1.427	0.000404
S	484	E484Q	Gaa	Caa	8	8	B.1.526	0.000188
S	484	E484Q	Gaa	Caa	7	7	B.1.1.348	0.005573
S	484	E484Q	Gaa	Caa	7	7	B.1.1.359	0.194444
S	484	E484Q	Gaa	Caa	6	6	AY.13	0.000966
S	484	E484Q	Gaa	Caa	6	6	AY.3	0.00006
S	484	E484Q	Gaa	Caa	6	6	AY.42	0.000241
S	484	E484Q	Gaa	Caa	6	6	AY.54	0.000572
S	484	E484Q	Gaa	Caa	6	6	B.1.1.28	0.001867
S	484	E484Q	Gaa	Caa	5	5	AY.4.5	0.000537
S	484	E484Q	Gaa	Caa	5	5	AY.47	0.000156
S	484	E484Q	Gaa	Caa	5	5	AY.59	0.002648
S	484	E484Q	Gaa	Caa	5	5	AY.65	0.002665
S	484	E484Q	Gaa	Caa	5	5	AY.98.1	0.000242
S	484	E484Q	Gaa	Caa	5	5	B.1.177.12	0.000758
S	484	E484Q	Gaa	Caa	5	5	B.1.258	0.000333
S	484	E484Q	Gaa	Caa	4	4	AY.116	0.001147
S	484	E484Q	Gaa	Caa	4	4	AY.12	0.001264
S	484	E484Q	Gaa	Caa	4	4	AY.34	0.000388
S	484	E484Q	Gaa	Caa	4	4	AY.46.4	0.000658
S	484	E484Q	Gaa	Caa	4	4	AY.5.4	0.001107
S	484	E484Q	Gaa	Caa	4	4	AY.67	0.001857
S	484	E484Q	Gaa	Caa	4	4	AY.68	0.001095
S	484	E484Q	Gaa	Caa	4	4	AY.74	0.000463
S	484	E484Q	Gaa	Caa	4	4	AY.75.1	0.000721
S	484	E484Q	Gaa	Caa	4	4	B.1.157	0.01194
S	484	E484Q	Gaa	Caa	4	4	B.1.258.17	0.000416
S	484	E484Q	Gaa	Caa	4	4	B.1.595	0.001044
S	484	E484Q	Gaa	Caa	4	4	B.1.599	0.014599
S	484	E484Q	Gaa	Caa	3	3	AY.104	0.005952
S	484	E484Q	Gaa	Caa	3	3	AY.118	0.000188
S	484	E484Q	Gaa	Caa	3	3	AY.34.1	0.00153
S	484	E484Q	Gaa	Caa	3	3	AY.46.2	0.001906
S	484	E484Q	Gaa	Caa	3	3	AY.6	0.000123
S	484	E484Q	Gaa	Caa	3	3	AY.95	0.002283
S	484	E484Q	Gaa	Caa	3	3	AY.98	0.000237
S	484	E484Q	Gaa	Caa	3	3	B.1.1.166	0.1
S	484	E484Q	Gaa	Caa	3	3	B.1.1.311	0.001074
S	484	E484Q	Gaa	Caa	3	3	B.1.1.519	0.000119
S	484	E484Q	Gaa	Caa	3	3	B.1.160	0.000094
S	484	E484Q	Gaa	Caa	3	3	B.1.177.21	0.000229
S	484	E484Q	Gaa	Caa	3	3	B.1.234	0.000396
S	484	E484Q	Gaa	Caa	3	3	B.1.524	0.004219
S	484	E484Q	Gaa	Caa	3	3	Q.8	0.000495
S	484	E484Q	Gaa	Caa	2	2	AY.114	0.000462
S	484	E484Q	Gaa	Caa	2	2	AY.16	0.000759
S	484	E484Q	Gaa	Caa	2	2	AY.16.1	0.00094
S	484	E484Q	Gaa	Caa	2	2	AY.27	0.000129
S	484	E484Q	Gaa	Caa	2	2	AY.4.2	0.000043
S	484	E484Q	Gaa	Caa	2	2	AY.51	0.001818
S	484	E484Q	Gaa	Caa	2	2	AY.84	0.000875
S	484	E484Q	Gaa	Caa	2	2	AY.88	0.001768
S	484	E484Q	Gaa	Caa	2	2	AY.90	0.001369
S	484	E484Q	Gaa	Caa	2	2	AY.92	0.000575
S	484	E484Q	Gaa	Caa	2	2	AY.99	0.002099
S	484	E484Q	Gaa	Caa	2	2	B	0.000256
S	484	E484Q	Gaa	Caa	2	2	B.1.1.192	0.004619
S	484	E484Q	Gaa	Caa	2	2	B.1.1.25	0.001137
S	484	E484Q	Gaa	Caa	2	2	B.1.1.328	0.033898
S	484	E484Q	Gaa	Caa	2	2	B.1.1.432	0.002532
S	484	E484Q	Gaa	Caa	2	2	B.1.177.52	0.003515
S	484	E484Q	Gaa	Caa	2	2	B.1.177.73	0.001133
S	484	E484Q	Gaa	Caa	2	2	B.1.177.86	0.000367
S	484	E484Q	Gaa	Caa	2	2	B.1.210	0.004264
S	484	E484Q	Gaa	Caa	2	2	B.1.221.3	0.001667
S	484	E484Q	Gaa	Caa	2	2	B.1.320	0.002491
S	484	E484Q	Gaa	Caa	2	2	B.1.36	0.000292
S	484	E484Q	Gaa	Caa	2	2	B.1.36.8	0.002
S	484	E484Q	Gaa	Caa	2	2	B.1.409	0.001563
S	484	E484Q	Gaa	Caa	2	2	B.1.438.1	0.000215
S	484	E484Q	Gaa	Caa	2	2	B.1.509	0.001732
S	484	E484Q	Gaa	Caa	2	2	B.1.537	0.04
S	484	E484Q	Gaa	Caa	2	2	B.1.575	0.000607
S	484	E484Q	Gaa	Caa	1	1	A.2.5	0.000499
S	484	E484Q	Gaa	Caa	1	1	A.23.1	0.000704
S	484	E484Q	Gaa	Caa	1	1	AE.1	0.011364
S	484	E484Q	Gaa	Caa	1	1	AY.106	0.000335
S	484	E484Q	Gaa	Caa	1	1	AY.109	0.00074
S	484	E484Q	Gaa	Caa	1	1	AY.120.2.1	0.000498
S	484	E484Q	Gaa	Caa	1	1	AY.23.1	0.000417
S	484	E484Q	Gaa	Caa	1	1	AY.24	0.000431
S	484	E484Q	Gaa	Caa	1	1	AY.28	0.00189
S	484	E484Q	Gaa	Caa	1	1	AY.30	0.000396
S	484	E484Q	Gaa	Caa	1	1	AY.32	0.000532
S	484	E484Q	Gaa	Caa	1	1	AY.37	0.000316
S	484	E484Q	Gaa	Caa	1	1	AY.38	0.000499
S	484	E484Q	Gaa	Caa	1	1	AY.4.1	0.000737
S	484	E484Q	Gaa	Caa	1	1	AY.4.2.1	0.000149
S	484	E484Q	Gaa	Caa	1	1	AY.4.4	0.000409
S	484	E484Q	Gaa	Caa	1	1	AY.46.1	0.001027
S	484	E484Q	Gaa	Caa	1	1	AY.46.3	0.000934
S	484	E484Q	Gaa	Caa	1	1	AY.49	0.003195
S	484	E484Q	Gaa	Caa	1	1	AY.53	0.000288
S	484	E484Q	Gaa	Caa	1	1	AY.58	0.000907
S	484	E484Q	Gaa	Caa	1	1	AY.60	0.000938
S	484	E484Q	Gaa	Caa	1	1	AY.62	0.000436
S	484	E484Q	Gaa	Caa	1	1	AY.7.1	0.000113
S	484	E484Q	Gaa	Caa	1	1	AY.73	0.000665
S	484	E484Q	Gaa	Caa	1	1	AY.85	0.000427
S	484	E484Q	Gaa	Caa	1	1	AY.89	0.004902
S	484	E484Q	Gaa	Caa	1	1	AY.9	0.000068
S	484	E484Q	Gaa	Caa	1	1	AY.93	0.000273
S	484	E484Q	Gaa	Caa	1	1	AY.99.1	0.001553
S	484	E484Q	Gaa	Caa	1	1	B.1.1.118	0.010204
S	484	E484Q	Gaa	Caa	1	1	B.1.1.135	0.004695
S	484	E484Q	Gaa	Caa	1	1	B.1.1.159	0.004673
S	484	E484Q	Gaa	Caa	1	1	B.1.1.170	0.001247
S	484	E484Q	Gaa	Caa	1	1	B.1.1.216	0.00089
S	484	E484Q	Gaa	Caa	1	1	B.1.1.222	0.000204
S	484	E484Q	Gaa	Caa	1	1	B.1.1.232	0.001815
S	484	E484Q	Gaa	Caa	1	1	B.1.1.241	0.00207
S	484	E484Q	Gaa	Caa	1	1	B.1.1.263	0.001558
S	484	E484Q	Gaa	Caa	1	1	B.1.1.297	0.002237
S	484	E484Q	Gaa	Caa	1	1	B.1.1.306	0.000438
S	484	E484Q	Gaa	Caa	1	1	B.1.1.351	0.002793
S	484	E484Q	Gaa	Caa	1	1	B.1.1.402	0.011111
S	484	E484Q	Gaa	Caa	1	1	B.1.1.409	0.002833
S	484	E484Q	Gaa	Caa	1	1	B.1.1.416	0.000905
S	484	E484Q	Gaa	Caa	1	1	B.1.1.434	0.000349
S	484	E484Q	Gaa	Caa	1	1	B.1.1.486	0.001577
S	484	E484Q	Gaa	Caa	1	1	B.1.106	0.03125
S	484	E484Q	Gaa	Caa	1	1	B.1.160.28	0.002924
S	484	E484Q	Gaa	Caa	1	1	B.1.177.76	0.002494
S	484	E484Q	Gaa	Caa	1	1	B.1.222	0.001692
S	484	E484Q	Gaa	Caa	1	1	B.1.232	0.000537
S	484	E484Q	Gaa	Caa	1	1	B.1.237	0.004975
S	484	E484Q	Gaa	Caa	1	1	B.1.241	0.000812
S	484	E484Q	Gaa	Caa	1	1	B.1.247	0.014925
S	484	E484Q	Gaa	Caa	1	1	B.1.311	0.000275
S	484	E484Q	Gaa	Caa	1	1	B.1.367	0.000792
S	484	E484Q	Gaa	Caa	1	1	B.1.396	0.000706
S	484	E484Q	Gaa	Caa	1	1	B.1.400	0.000429
S	484	E484Q	Gaa	Caa	1	1	B.1.466	0.023256
S	484	E484Q	Gaa	Caa	1	1	B.1.468	0.005714
S	484	E484Q	Gaa	Caa	1	1	B.1.551	0.00129
S	484	E484Q	Gaa	Caa	1	1	B.1.560	0.00463
S	484	E484Q	Gaa	Caa	1	1	B.1.564	0.000426
S	484	E484Q	Gaa	Caa	1	1	B.1.576	0.000907
S	484	E484Q	Gaa	Caa	1	1	B.1.580	0.004065
S	484	E484Q	Gaa	Caa	1	1	B.1.588	0.00091
S	484	E484Q	Gaa	Caa	1	1	B.1.609	0.000479
S	484	E484Q	Gaa	Caa	1	1	B.1.621	0.000089
S	484	E484Q	Gaa	Caa	1	1	B.1.625	0.002353
S	484	E484Q	Gaa	Caa	1	1	B.1.83	0.015385
S	484	E484Q	Gaa	Caa	1	1	B.28	0.003279
S	484	E484Q	Gaa	Caa	1	1	B.4	0.002208
S	484	E484Q	Gaa	Caa	1	1	C.1	0.002392
S	484	E484Q	Gaa	Caa	1	1	C.18	0.002591
S	484	E484Q	Gaa	Caa	1	1	C.37	0.000116
S	484	E484Q	Gaa	Caa	1	1	C.38	0.008065
S	484	E484Q	Gaa	Caa	1	1	Q.1	0.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.