CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = D80D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	80	D80D		syn	gaT	gaC	2454	2454	1	21800-21802

Details of the mutation D80D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	80	D80D	gaT	gaC	2454	2454	All	0.000469
S	80	D80D	gaT	gaC	895	895	B.1.617.2	0.00337
S	80	D80D	gaT	gaC	229	229	AY.4.2.1	0.034118
S	80	D80D	gaT	gaC	182	182	AY.103	0.00113
S	80	D80D	gaT	gaC	161	161	B.1.1.7	0.000144
S	80	D80D	gaT	gaC	87	87	AY.4	0.000135
S	80	D80D	gaT	gaC	85	85	B.1	0.000779
S	80	D80D	gaT	gaC	77	77	AY.43	0.000341
S	80	D80D	gaT	gaC	74	74	AY.47	0.002302
S	80	D80D	gaT	gaC	70	70	B.1.1	0.00127
S	80	D80D	gaT	gaC	30	30	B.1.596	0.002614
S	80	D80D	gaT	gaC	28	28	B.1.2	0.000247
S	80	D80D	gaT	gaC	24	24	AY.70	0.005004
S	80	D80D	gaT	gaC	23	23	AY.52	0.01873
S	80	D80D	gaT	gaC	22	22	B.1.565	0.017828
S	80	D80D	gaT	gaC	22	22	P.1.14	0.001052
S	80	D80D	gaT	gaC	20	20	AY.3	0.000199
S	80	D80D	gaT	gaC	19	19	AY.44	0.000116
S	80	D80D	gaT	gaC	18	18	B.1.438.1	0.001931
S	80	D80D	gaT	gaC	17	17	AY.25	0.000102
S	80	D80D	gaT	gaC	17	17	B.1.221.1	0.049419
S	80	D80D	gaT	gaC	16	16	B.1.160	0.000499
S	80	D80D	gaT	gaC	16	16	P.1	0.000252
S	80	D80D	gaT	gaC	15	15	AY.39	0.000371
S	80	D80D	gaT	gaC	15	15	AY.5	0.00031
S	80	D80D	gaT	gaC	15	15	AY.5.3	0.005061
S	80	D80D	gaT	gaC	13	13	B.1.243	0.000905
S	80	D80D	gaT	gaC	13	13	B.1.526	0.000306
S	80	D80D	gaT	gaC	11	11	A	0.004257
S	80	D80D	gaT	gaC	10	10	AY.29	0.000158
S	80	D80D	gaT	gaC	9	9	AY.57	0.005906
S	80	D80D	gaT	gaC	9	9	B.1.517	0.003843
S	80	D80D	gaT	gaC	8	8	AY.33	0.000534
S	80	D80D	gaT	gaC	8	8	B.1.1.434	0.002788
S	80	D80D	gaT	gaC	7	7	AY.120	0.00026
S	80	D80D	gaT	gaC	7	7	B.1.1.26	0.036649
S	80	D80D	gaT	gaC	6	6	AY.3.1	0.000512
S	80	D80D	gaT	gaC	6	6	B.1.429	0.000141
S	80	D80D	gaT	gaC	5	5	AY.23	0.000349
S	80	D80D	gaT	gaC	5	5	B.1.1.519	0.000199
S	80	D80D	gaT	gaC	5	5	B.1.177	0.000066
S	80	D80D	gaT	gaC	5	5	B.1.36.31	0.008757
S	80	D80D	gaT	gaC	4	4	AY.102	0.000106
S	80	D80D	gaT	gaC	4	4	AY.116	0.001147
S	80	D80D	gaT	gaC	4	4	AY.118	0.000251
S	80	D80D	gaT	gaC	4	4	AY.20	0.000155
S	80	D80D	gaT	gaC	4	4	AY.26	0.000113
S	80	D80D	gaT	gaC	4	4	AY.4.2	0.000087
S	80	D80D	gaT	gaC	4	4	AY.7	0.000784
S	80	D80D	gaT	gaC	4	4	AY.71	0.0019
S	80	D80D	gaT	gaC	4	4	B.1.258	0.000266
S	80	D80D	gaT	gaC	4	4	B.1.427	0.000202
S	80	D80D	gaT	gaC	3	3	AY.100	0.000138
S	80	D80D	gaT	gaC	3	3	AY.119	0.000106
S	80	D80D	gaT	gaC	3	3	AY.86	0.00249
S	80	D80D	gaT	gaC	3	3	B.1.1.159	0.014019
S	80	D80D	gaT	gaC	3	3	B.1.1.464	0.004418
S	80	D80D	gaT	gaC	3	3	B.1.36.10	0.014354
S	80	D80D	gaT	gaC	3	3	B.1.466.2	0.001174
S	80	D80D	gaT	gaC	3	3	B.1.621	0.000266
S	80	D80D	gaT	gaC	2	2	A.2.5	0.000998
S	80	D80D	gaT	gaC	2	2	AY.1	0.000791
S	80	D80D	gaT	gaC	2	2	AY.24	0.000862
S	80	D80D	gaT	gaC	2	2	AY.39.1	0.000079
S	80	D80D	gaT	gaC	2	2	AY.4.5	0.000215
S	80	D80D	gaT	gaC	2	2	AY.54	0.000191
S	80	D80D	gaT	gaC	2	2	AY.58	0.001815
S	80	D80D	gaT	gaC	2	2	AY.59	0.001059
S	80	D80D	gaT	gaC	2	2	AY.67	0.000929
S	80	D80D	gaT	gaC	2	2	AY.75	0.000112
S	80	D80D	gaT	gaC	2	2	AY.9	0.000135
S	80	D80D	gaT	gaC	2	2	AZ.3	0.00304
S	80	D80D	gaT	gaC	2	2	B.1.1.63	0.000772
S	80	D80D	gaT	gaC	2	2	B.1.177.73	0.001133
S	80	D80D	gaT	gaC	2	2	B.1.221	0.000142
S	80	D80D	gaT	gaC	2	2	B.1.258.11	0.000793
S	80	D80D	gaT	gaC	2	2	B.1.36.33	0.015152
S	80	D80D	gaT	gaC	2	2	B.1.474	0.003802
S	80	D80D	gaT	gaC	2	2	B.1.628	0.000705
S	80	D80D	gaT	gaC	2	2	P.1.9	0.009615
S	80	D80D	gaT	gaC	2	2	P.6	0.006289
S	80	D80D	gaT	gaC	2	2	Q.3	0.00029
S	80	D80D	gaT	gaC	1	1	A.1	0.000282
S	80	D80D	gaT	gaC	1	1	AY.108	0.001103
S	80	D80D	gaT	gaC	1	1	AY.110	0.000113
S	80	D80D	gaT	gaC	1	1	AY.113	0.000142
S	80	D80D	gaT	gaC	1	1	AY.116.1	0.000311
S	80	D80D	gaT	gaC	1	1	AY.117	0.000085
S	80	D80D	gaT	gaC	1	1	AY.12	0.000316
S	80	D80D	gaT	gaC	1	1	AY.121	0.000135
S	80	D80D	gaT	gaC	1	1	AY.16.1	0.00047
S	80	D80D	gaT	gaC	1	1	AY.29.1	0.000221
S	80	D80D	gaT	gaC	1	1	AY.34	0.000097
S	80	D80D	gaT	gaC	1	1	AY.36	0.000148
S	80	D80D	gaT	gaC	1	1	AY.46.6	0.000072
S	80	D80D	gaT	gaC	1	1	AY.63	0.000387
S	80	D80D	gaT	gaC	1	1	AY.77	0.001127
S	80	D80D	gaT	gaC	1	1	AY.81	0.001992
S	80	D80D	gaT	gaC	1	1	AY.85	0.000427
S	80	D80D	gaT	gaC	1	1	AY.91	0.00073
S	80	D80D	gaT	gaC	1	1	AY.98.1	0.000048
S	80	D80D	gaT	gaC	1	1	B.1.1.222	0.000204
S	80	D80D	gaT	gaC	1	1	B.1.1.28	0.000311
S	80	D80D	gaT	gaC	1	1	B.1.1.306	0.000438
S	80	D80D	gaT	gaC	1	1	B.1.1.334	0.016393
S	80	D80D	gaT	gaC	1	1	B.1.1.37	0.000193
S	80	D80D	gaT	gaC	1	1	B.1.1.378	0.007299
S	80	D80D	gaT	gaC	1	1	B.1.1.409	0.002833
S	80	D80D	gaT	gaC	1	1	B.1.1.413	0.006897
S	80	D80D	gaT	gaC	1	1	B.1.111	0.001175
S	80	D80D	gaT	gaC	1	1	B.1.177.21	0.000076
S	80	D80D	gaT	gaC	1	1	B.1.177.65	0.000665
S	80	D80D	gaT	gaC	1	1	B.1.215	0.009615
S	80	D80D	gaT	gaC	1	1	B.1.258.14	0.00098
S	80	D80D	gaT	gaC	1	1	B.1.36	0.000146
S	80	D80D	gaT	gaC	1	1	B.1.423	0.010204
S	80	D80D	gaT	gaC	1	1	B.1.471	0.002732
S	80	D80D	gaT	gaC	1	1	B.1.568	0.001111
S	80	D80D	gaT	gaC	1	1	B.1.577	0.000687
S	80	D80D	gaT	gaC	1	1	B.1.609	0.000479
S	80	D80D	gaT	gaC	1	1	B.1.617.1	0.000129
S	80	D80D	gaT	gaC	1	1	C.26	0.007353
S	80	D80D	gaT	gaC	1	1	C.37	0.000116
S	80	D80D	gaT	gaC	1	1	P.1.15	0.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.