CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = D627D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	627	D627D		syn	gaT	gaC	1375	1375	1	23441-23443

Details of the mutation D627D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	627	D627D	gaT	gaC	1375	1375	All	0.000263
S	627	D627D	gaT	gaC	269	269	B.1.1.7	0.000241
S	627	D627D	gaT	gaC	131	131	B.1.1.214	0.007265
S	627	D627D	gaT	gaC	130	130	AY.44	0.000791
S	627	D627D	gaT	gaC	96	96	B.1.420	1
S	627	D627D	gaT	gaC	79	79	B.1.1.176	0.03471
S	627	D627D	gaT	gaC	70	70	B.1.2	0.000616
S	627	D627D	gaT	gaC	60	60	B.1.617.2	0.000226
S	627	D627D	gaT	gaC	57	57	B.1.177	0.000751
S	627	D627D	gaT	gaC	56	56	B.1.409	0.04375
S	627	D627D	gaT	gaC	50	50	AY.4	0.000078
S	627	D627D	gaT	gaC	49	49	AY.25	0.000295
S	627	D627D	gaT	gaC	28	28	AY.39	0.000692
S	627	D627D	gaT	gaC	25	25	B.1	0.000229
S	627	D627D	gaT	gaC	19	19	AY.26	0.000538
S	627	D627D	gaT	gaC	16	16	AY.100	0.000736
S	627	D627D	gaT	gaC	16	16	AY.34.1	0.008159
S	627	D627D	gaT	gaC	14	14	AY.34	0.001358
S	627	D627D	gaT	gaC	10	10	B.1.1.519	0.000397
S	627	D627D	gaT	gaC	10	10	P.1	0.000158
S	627	D627D	gaT	gaC	9	9	AY.43	0.00004
S	627	D627D	gaT	gaC	9	9	B.1.526	0.000212
S	627	D627D	gaT	gaC	8	8	AY.92	0.002298
S	627	D627D	gaT	gaC	8	8	B.1.621	0.000708
S	627	D627D	gaT	gaC	7	7	AY.102	0.000186
S	627	D627D	gaT	gaC	7	7	AY.3	0.00007
S	627	D627D	gaT	gaC	7	7	AY.54	0.000667
S	627	D627D	gaT	gaC	7	7	AY.98.1	0.000339
S	627	D627D	gaT	gaC	7	7	C.23	0.040698
S	627	D627D	gaT	gaC	7	7	C.37	0.000812
S	627	D627D	gaT	gaC	5	5	B.1.1	0.000091
S	627	D627D	gaT	gaC	4	4	AY.103	0.000025
S	627	D627D	gaT	gaC	4	4	AY.118	0.000251
S	627	D627D	gaT	gaC	4	4	AY.4.5	0.00043
S	627	D627D	gaT	gaC	4	4	AY.47	0.000124
S	627	D627D	gaT	gaC	4	4	AY.5	0.000083
S	627	D627D	gaT	gaC	4	4	R.1	0.00036
S	627	D627D	gaT	gaC	3	3	AY.120	0.000112
S	627	D627D	gaT	gaC	3	3	B.1.1.148	0.026316
S	627	D627D	gaT	gaC	3	3	B.1.258	0.0002
S	627	D627D	gaT	gaC	3	3	B.1.596	0.000261
S	627	D627D	gaT	gaC	2	2	AY.23	0.000139
S	627	D627D	gaT	gaC	2	2	AY.46.5	0.000397
S	627	D627D	gaT	gaC	2	2	AY.9.2	0.000073
S	627	D627D	gaT	gaC	2	2	B.1.160.17	0.003401
S	627	D627D	gaT	gaC	2	2	B.1.258.17	0.000208
S	627	D627D	gaT	gaC	2	2	B.1.351	0.000059
S	627	D627D	gaT	gaC	2	2	B.1.389	0.002004
S	627	D627D	gaT	gaC	2	2	B.1.429	0.000047
S	627	D627D	gaT	gaC	2	2	B.1.468	0.011429
S	627	D627D	gaT	gaC	2	2	Q.1	0.000253
S	627	D627D	gaT	gaC	1	1	A.23.1	0.000704
S	627	D627D	gaT	gaC	1	1	AY.106	0.000335
S	627	D627D	gaT	gaC	1	1	AY.120.2.1	0.000498
S	627	D627D	gaT	gaC	1	1	AY.18	0.010101
S	627	D627D	gaT	gaC	1	1	AY.20	0.000039
S	627	D627D	gaT	gaC	1	1	AY.27	0.000065
S	627	D627D	gaT	gaC	1	1	AY.29	0.000016
S	627	D627D	gaT	gaC	1	1	AY.30	0.000396
S	627	D627D	gaT	gaC	1	1	AY.39.1	0.00004
S	627	D627D	gaT	gaC	1	1	AY.4.3	0.000842
S	627	D627D	gaT	gaC	1	1	AY.46	0.000104
S	627	D627D	gaT	gaC	1	1	AY.6	0.000041
S	627	D627D	gaT	gaC	1	1	AY.61	0.000105
S	627	D627D	gaT	gaC	1	1	AY.68	0.000274
S	627	D627D	gaT	gaC	1	1	AY.7	0.000196
S	627	D627D	gaT	gaC	1	1	AY.74	0.000116
S	627	D627D	gaT	gaC	1	1	AY.75.1	0.00018
S	627	D627D	gaT	gaC	1	1	AY.9	0.000068
S	627	D627D	gaT	gaC	1	1	AY.98	0.000079
S	627	D627D	gaT	gaC	1	1	AY.99.2	0.000092
S	627	D627D	gaT	gaC	1	1	B.1.1.1	0.000327
S	627	D627D	gaT	gaC	1	1	B.1.1.191	0.004762
S	627	D627D	gaT	gaC	1	1	B.1.1.230	0.009174
S	627	D627D	gaT	gaC	1	1	B.1.1.240	0.004695
S	627	D627D	gaT	gaC	1	1	B.1.1.261	0.008621
S	627	D627D	gaT	gaC	1	1	B.1.1.28	0.000311
S	627	D627D	gaT	gaC	1	1	B.1.1.284	0.000107
S	627	D627D	gaT	gaC	1	1	B.1.1.294	0.001266
S	627	D627D	gaT	gaC	1	1	B.1.1.318	0.000302
S	627	D627D	gaT	gaC	1	1	B.1.1.348	0.000796
S	627	D627D	gaT	gaC	1	1	B.1.1.45	0.014085
S	627	D627D	gaT	gaC	1	1	B.1.110.3	0.000718
S	627	D627D	gaT	gaC	1	1	B.1.146	0.004237
S	627	D627D	gaT	gaC	1	1	B.1.160	0.000031
S	627	D627D	gaT	gaC	1	1	B.1.177.23	0.003236
S	627	D627D	gaT	gaC	1	1	B.1.177.8	0.000752
S	627	D627D	gaT	gaC	1	1	B.1.177.81	0.000189
S	627	D627D	gaT	gaC	1	1	B.1.201	0.005682
S	627	D627D	gaT	gaC	1	1	B.1.221	0.000071
S	627	D627D	gaT	gaC	1	1	B.1.258.19	0.007092
S	627	D627D	gaT	gaC	1	1	B.1.258.3	0.001675
S	627	D627D	gaT	gaC	1	1	B.1.279	0.000514
S	627	D627D	gaT	gaC	1	1	B.1.311	0.000275
S	627	D627D	gaT	gaC	1	1	B.1.333	0.010526
S	627	D627D	gaT	gaC	1	1	B.1.427	0.00005
S	627	D627D	gaT	gaC	1	1	B.1.580	0.004065
S	627	D627D	gaT	gaC	1	1	B.1.606	0.006024
S	627	D627D	gaT	gaC	1	1	B.1.610	0.003546
S	627	D627D	gaT	gaC	1	1	B.1.9.5	0.005682
S	627	D627D	gaT	gaC	1	1	B.40	0.000364
S	627	D627D	gaT	gaC	1	1	P.1.14	0.000048
S	627	D627D	gaT	gaC	1	1	P.1.8	0.004785
S	627	D627D	gaT	gaC	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.