CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 294 | D294D | syn | gaC | gaT | 27092 | 27092 | 1 | 22442-22444 |
Details of the mutation D294D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 294 | D294D | gaC | gaT | 27092 | 27092 | All | 0.005182 |
S | 294 | D294D | gaC | gaT | 6228 | 6228 | B.1.36 | 0.908666 |
S | 294 | D294D | gaC | gaT | 2276 | 2276 | B.1.36.18 | 0.956303 |
S | 294 | D294D | gaC | gaT | 1880 | 1880 | B.1.36.17 | 0.928854 |
S | 294 | D294D | gaC | gaT | 1713 | 1713 | B.1.36.29 | 0.886187 |
S | 294 | D294D | gaC | gaT | 1657 | 1657 | B.1.36.36 | 0.997592 |
S | 294 | D294D | gaC | gaT | 1309 | 1309 | B.1.36.27 | 0.999237 |
S | 294 | D294D | gaC | gaT | 937 | 937 | B.1.36.8 | 0.937 |
S | 294 | D294D | gaC | gaT | 817 | 817 | B.1.36.1 | 0.931585 |
S | 294 | D294D | gaC | gaT | 786 | 786 | B.1.36.22 | 0.949275 |
S | 294 | D294D | gaC | gaT | 590 | 590 | B.1.36.38 | 0.968801 |
S | 294 | D294D | gaC | gaT | 544 | 544 | B.1.1.7 | 0.000487 |
S | 294 | D294D | gaC | gaT | 538 | 538 | B.1.36.31 | 0.942207 |
S | 294 | D294D | gaC | gaT | 464 | 464 | B.1.177 | 0.00611 |
S | 294 | D294D | gaC | gaT | 461 | 461 | B.1.36.21 | 0.99568 |
S | 294 | D294D | gaC | gaT | 453 | 453 | B.1.36.25 | 1 |
S | 294 | D294D | gaC | gaT | 433 | 433 | B.1.36.39 | 0.960089 |
S | 294 | D294D | gaC | gaT | 408 | 408 | B.1.36.16 | 0.581197 |
S | 294 | D294D | gaC | gaT | 360 | 360 | B.1.36.37 | 1 |
S | 294 | D294D | gaC | gaT | 359 | 359 | B.1.36.35 | 0.934896 |
S | 294 | D294D | gaC | gaT | 340 | 340 | B.1.36.26 | 0.971429 |
S | 294 | D294D | gaC | gaT | 301 | 301 | B.1.617.2 | 0.001133 |
S | 294 | D294D | gaC | gaT | 294 | 294 | B.1.36.9 | 0.945338 |
S | 294 | D294D | gaC | gaT | 277 | 277 | B.1 | 0.002537 |
S | 294 | D294D | gaC | gaT | 254 | 254 | AY.4 | 0.000395 |
S | 294 | D294D | gaC | gaT | 248 | 248 | B.1.36.7 | 0.992 |
S | 294 | D294D | gaC | gaT | 221 | 221 | AY.43 | 0.000979 |
S | 294 | D294D | gaC | gaT | 178 | 178 | B.1.36.10 | 0.851675 |
S | 294 | D294D | gaC | gaT | 174 | 174 | B.1.468 | 0.994286 |
S | 294 | D294D | gaC | gaT | 171 | 171 | B.1.36.28 | 0.982759 |
S | 294 | D294D | gaC | gaT | 156 | 156 | B.1.36.24 | 0.962963 |
S | 294 | D294D | gaC | gaT | 131 | 131 | AY.47 | 0.004075 |
S | 294 | D294D | gaC | gaT | 129 | 129 | B.1.36.33 | 0.977273 |
S | 294 | D294D | gaC | gaT | 116 | 116 | AY.103 | 0.00072 |
S | 294 | D294D | gaC | gaT | 104 | 104 | B.1.36.12 | 1 |
S | 294 | D294D | gaC | gaT | 95 | 95 | P.1 | 0.001497 |
S | 294 | D294D | gaC | gaT | 91 | 91 | B.1.2 | 0.000801 |
S | 294 | D294D | gaC | gaT | 80 | 80 | AY.5 | 0.001652 |
S | 294 | D294D | gaC | gaT | 69 | 69 | B.1.36.2 | 0.741935 |
S | 294 | D294D | gaC | gaT | 60 | 60 | AY.39 | 0.001483 |
S | 294 | D294D | gaC | gaT | 58 | 58 | AY.3 | 0.000577 |
S | 294 | D294D | gaC | gaT | 58 | 58 | B.1.1 | 0.001052 |
S | 294 | D294D | gaC | gaT | 58 | 58 | B.1.36.23 | 0.95082 |
S | 294 | D294D | gaC | gaT | 56 | 56 | B.1.110.3 | 0.04023 |
S | 294 | D294D | gaC | gaT | 56 | 56 | B.1.326 | 0.424242 |
S | 294 | D294D | gaC | gaT | 56 | 56 | B.1.36.20 | 0.949153 |
S | 294 | D294D | gaC | gaT | 53 | 53 | AY.25 | 0.000319 |
S | 294 | D294D | gaC | gaT | 48 | 48 | B.1.113 | 0.75 |
S | 294 | D294D | gaC | gaT | 47 | 47 | B.1.36.34 | 1 |
S | 294 | D294D | gaC | gaT | 45 | 45 | AY.44 | 0.000274 |
S | 294 | D294D | gaC | gaT | 43 | 43 | B.1.526 | 0.001011 |
S | 294 | D294D | gaC | gaT | 35 | 35 | AY.29 | 0.000552 |
S | 294 | D294D | gaC | gaT | 34 | 34 | AY.118 | 0.00213 |
S | 294 | D294D | gaC | gaT | 30 | 30 | A.1 | 0.008455 |
S | 294 | D294D | gaC | gaT | 30 | 30 | AY.119 | 0.001059 |
S | 294 | D294D | gaC | gaT | 29 | 29 | B.1.234 | 0.003826 |
S | 294 | D294D | gaC | gaT | 25 | 25 | C.37 | 0.002902 |
S | 294 | D294D | gaC | gaT | 23 | 23 | B | 0.00294 |
S | 294 | D294D | gaC | gaT | 23 | 23 | B.1.260 | 0.076923 |
S | 294 | D294D | gaC | gaT | 22 | 22 | B.1.247 | 0.328358 |
S | 294 | D294D | gaC | gaT | 20 | 20 | AY.39.1 | 0.000792 |
S | 294 | D294D | gaC | gaT | 20 | 20 | B.1.221 | 0.001421 |
S | 294 | D294D | gaC | gaT | 18 | 18 | AY.34 | 0.001745 |
S | 294 | D294D | gaC | gaT | 17 | 17 | AY.75 | 0.000952 |
S | 294 | D294D | gaC | gaT | 16 | 16 | B.1.1.284 | 0.001718 |
S | 294 | D294D | gaC | gaT | 14 | 14 | B.1.258.17 | 0.001456 |
S | 294 | D294D | gaC | gaT | 13 | 13 | AY.113 | 0.001851 |
S | 294 | D294D | gaC | gaT | 13 | 13 | AY.20 | 0.000505 |
S | 294 | D294D | gaC | gaT | 13 | 13 | AY.46 | 0.001353 |
S | 294 | D294D | gaC | gaT | 12 | 12 | AY.9.1 | 0.001005 |
S | 294 | D294D | gaC | gaT | 12 | 12 | B.1.1.39 | 0.006116 |
S | 294 | D294D | gaC | gaT | 12 | 12 | B.1.184 | 0.705882 |
S | 294 | D294D | gaC | gaT | 11 | 11 | AY.33 | 0.000735 |
S | 294 | D294D | gaC | gaT | 9 | 9 | AY.102 | 0.000239 |
S | 294 | D294D | gaC | gaT | 9 | 9 | AY.23 | 0.000628 |
S | 294 | D294D | gaC | gaT | 9 | 9 | AY.81 | 0.017928 |
S | 294 | D294D | gaC | gaT | 9 | 9 | B.1.1.406 | 0.058442 |
S | 294 | D294D | gaC | gaT | 9 | 9 | B.1.1.434 | 0.003137 |
S | 294 | D294D | gaC | gaT | 9 | 9 | B.1.258 | 0.000599 |
S | 294 | D294D | gaC | gaT | 8 | 8 | AY.100 | 0.000368 |
S | 294 | D294D | gaC | gaT | 8 | 8 | B.1.636 | 0.053691 |
S | 294 | D294D | gaC | gaT | 7 | 7 | B.1.160 | 0.000218 |
S | 294 | D294D | gaC | gaT | 7 | 7 | B.1.210 | 0.014925 |
S | 294 | D294D | gaC | gaT | 7 | 7 | B.1.429 | 0.000165 |
S | 294 | D294D | gaC | gaT | 6 | 6 | AY.4.2 | 0.00013 |
S | 294 | D294D | gaC | gaT | 6 | 6 | AY.73 | 0.003992 |
S | 294 | D294D | gaC | gaT | 6 | 6 | AY.88 | 0.005305 |
S | 294 | D294D | gaC | gaT | 6 | 6 | B.1.1.519 | 0.000238 |
S | 294 | D294D | gaC | gaT | 6 | 6 | B.1.533 | 0.057692 |
S | 294 | D294D | gaC | gaT | 5 | 5 | AY.26 | 0.000142 |
S | 294 | D294D | gaC | gaT | 5 | 5 | AY.36 | 0.000741 |
S | 294 | D294D | gaC | gaT | 5 | 5 | AY.42 | 0.000201 |
S | 294 | D294D | gaC | gaT | 5 | 5 | AY.9.2 | 0.000184 |
S | 294 | D294D | gaC | gaT | 5 | 5 | B.1.1.1 | 0.001633 |
S | 294 | D294D | gaC | gaT | 5 | 5 | D.2 | 0.000375 |
S | 294 | D294D | gaC | gaT | 5 | 5 | Q.3 | 0.000725 |
S | 294 | D294D | gaC | gaT | 5 | 5 | R.1 | 0.00045 |
S | 294 | D294D | gaC | gaT | 4 | 4 | A | 0.001548 |
S | 294 | D294D | gaC | gaT | 4 | 4 | AY.105 | 0.002572 |
S | 294 | D294D | gaC | gaT | 4 | 4 | AY.14 | 0.000352 |
S | 294 | D294D | gaC | gaT | 4 | 4 | AY.4.5 | 0.00043 |
S | 294 | D294D | gaC | gaT | 4 | 4 | AY.67 | 0.001857 |
S | 294 | D294D | gaC | gaT | 4 | 4 | B.1.177.21 | 0.000306 |
S | 294 | D294D | gaC | gaT | 4 | 4 | B.1.177.73 | 0.002265 |
S | 294 | D294D | gaC | gaT | 4 | 4 | B.1.214 | 0.014652 |
S | 294 | D294D | gaC | gaT | 4 | 4 | B.1.351 | 0.000119 |
S | 294 | D294D | gaC | gaT | 4 | 4 | B.1.596 | 0.000349 |
S | 294 | D294D | gaC | gaT | 4 | 4 | P.1.14 | 0.000191 |
S | 294 | D294D | gaC | gaT | 3 | 3 | AY.117 | 0.000254 |
S | 294 | D294D | gaC | gaT | 3 | 3 | AY.120 | 0.000112 |
S | 294 | D294D | gaC | gaT | 3 | 3 | AY.45 | 0.000365 |
S | 294 | D294D | gaC | gaT | 3 | 3 | AY.74 | 0.000347 |
S | 294 | D294D | gaC | gaT | 3 | 3 | AY.77 | 0.003382 |
S | 294 | D294D | gaC | gaT | 3 | 3 | AY.98 | 0.000237 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.1.1.222 | 0.000612 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.1.177.81 | 0.000568 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.1.281 | 0.065217 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.1.396 | 0.002117 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.1.525 | 0.000339 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.1.617.1 | 0.000387 |
S | 294 | D294D | gaC | gaT | 3 | 3 | B.6 | 0.00273 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.10 | 0.00106 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.110 | 0.000225 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.111 | 0.000366 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.16.1 | 0.00094 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.27 | 0.000129 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.3.1 | 0.000171 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.35 | 0.000466 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.46.6 | 0.000144 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.48 | 0.00093 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.53 | 0.000575 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.75.1 | 0.000361 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.84 | 0.000875 |
S | 294 | D294D | gaC | gaT | 2 | 2 | AY.9 | 0.000135 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.1.28 | 0.000622 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.1.521 | 0.010695 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.1.70 | 0.000682 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.177.16 | 0.001329 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.177.4 | 0.000422 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.177.44 | 0.001038 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.177.45 | 0.000762 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.243 | 0.000139 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.258.14 | 0.001961 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.340 | 0.008584 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.1.497 | 0.00063 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.4.1 | 0.037736 |
S | 294 | D294D | gaC | gaT | 2 | 2 | B.6.6 | 0.001778 |
S | 294 | D294D | gaC | gaT | 2 | 2 | C.2 | 0.032258 |
S | 294 | D294D | gaC | gaT | 2 | 2 | P.1.15 | 0.000465 |
S | 294 | D294D | gaC | gaT | 2 | 2 | P.2 | 0.000373 |
S | 294 | D294D | gaC | gaT | 2 | 2 | Q.8 | 0.00033 |
S | 294 | D294D | gaC | gaT | 1 | 1 | A.2.5.2 | 0.001572 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AD.2 | 0.000219 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AF.1 | 0.037037 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AH.3 | 0.003802 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.101 | 0.00049 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.104 | 0.001984 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.13 | 0.000161 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.29.1 | 0.000221 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.34.1 | 0.00051 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.37 | 0.000316 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.4.3 | 0.000842 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.46.4 | 0.000165 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.5.3 | 0.000337 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.52 | 0.000814 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.6 | 0.000041 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.65 | 0.000533 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.68 | 0.000274 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.7.1 | 0.000113 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.82 | 0.001357 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.92 | 0.000287 |
S | 294 | D294D | gaC | gaT | 1 | 1 | AY.98.1 | 0.000048 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.153 | 0.001095 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.176 | 0.000439 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.189 | 0.001513 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.210 | 0.005714 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.304 | 0.002809 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.306 | 0.000438 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.316 | 0.000925 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.33 | 0.000421 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.355 | 0.015385 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.37 | 0.000193 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.372 | 0.000689 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.413 | 0.006897 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.46 | 0.004367 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.51 | 0.001718 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.1.526 | 0.003546 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.127 | 0.002198 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.160.24 | 0.004425 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.160.30 | 0.002976 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.160.32 | 0.004292 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.160.7 | 0.002079 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.177.20 | 0.001517 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.177.57 | 0.000281 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.177.6 | 0.000977 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.177.60 | 0.000218 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.177.7 | 0.000165 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.177.77 | 0.000726 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.241 | 0.000812 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.279 | 0.000514 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.291 | 0.019231 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.311 | 0.000275 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.350 | 0.002933 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.369 | 0.000285 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.37 | 0.014706 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.427 | 0.00005 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.438.1 | 0.000107 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.456 | 0.003268 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.575 | 0.000303 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.1.621 | 0.000089 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.3 | 0.000831 |
S | 294 | D294D | gaC | gaT | 1 | 1 | B.55 | 0.00295 |
S | 294 | D294D | gaC | gaT | 1 | 1 | C.35 | 0.000774 |
S | 294 | D294D | gaC | gaT | 1 | 1 | C.36 | 0.000911 |
S | 294 | D294D | gaC | gaT | 1 | 1 | P.1.10 | 0.000269 |
S | 294 | D294D | gaC | gaT | 1 | 1 | P.1.10.1 | 0.00813 |
S | 294 | D294D | gaC | gaT | 1 | 1 | Q.1 | 0.000126 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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