CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : Mut = D1146H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S1146D1146HnonsynGacCac7367330.99592424998-25000
S1146D1146HnonsynGaCCaT73630.0040760924998-25000

Details of the mutation D1146H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S1146D1146HGacCac733736All0.00014
S1146D1146HGaCCaT3736All0.000001
S1146D1146HGacCac132132B.1.1.70.000118
S1146D1146HGacCac7272B.1.36.210.155508
S1146D1146HGacCac5858B.1.617.20.000218
S1146D1146HGacCac4646AY.40.000072
S1146D1146HGacCac4343B.1.930.040149
S1146D1146HGacCac4141AY.740.004742
S1146D1146HGacCac2323AY.1030.000143
S1146D1146HGacCac2222B.1.1940.88
S1146D1146HGacCac1919AY.420.000764
S1146D1146HGacCac1717AY.290.000268
S1146D1146HGacCac1414AY.430.000062
S1146D1146HGacCac1313AY.440.000079
S1146D1146HGacCac1212B.1.2210.000852
S1146D1146HGacCac1111AY.250.000066
S1146D1146HGacCac88B.1.1.5250.043716
S1146D1146HGacCac88B.1.4270.000404
S1146D1146HGacCac77AY.390.000173
S1146D1146HGacCac77B.10.000064
S1146D1146HGacCac67B.1.1770.000079
S1146D1146HGaCCaT17B.1.1770.000013
S1146D1146HGacCac77B.1.177.170.005747
S1146D1146HGacCac77B.1.5260.000165
S1146D1146HGacCac66B.1.10.000109
S1146D1146HGacCac66B.1.1.2140.000333
S1146D1146HGacCac66B.1.20.000053
S1146D1146HGacCac55B.1.1.5190.000199
S1146D1146HGacCac55B.1.1.700.001705
S1146D1146HGacCac55B.1.3510.000149
S1146D1146HGacCac44AY.1020.000106
S1146D1146HGacCac44AY.4.20.000087
S1146D1146HGacCac44B.1.2580.000266
S1146D1146HGacCac44B.1.36.180.001681
S1146D1146HGacCac44P.10.000063
S1146D1146HGacCac33AY.1090.002219
S1146D1146HGacCac33AY.260.000085
S1146D1146HGacCac33AY.30.00003
S1146D1146HGacCac33AY.46.60.000217
S1146D1146HGacCac33B.1.1.2220.000612
S1146D1146HGacCac33B.1.1.3170.001235
S1146D1146HGacCac33B.1.2320.001612
S1146D1146HGacCac33B.1.5250.000339
S1146D1146HGacCac33B.1.6270.006061
S1146D1146HGacCac120.055556
S1146D1146HGaCCaT120.055556
S1146D1146HGacCac22AY.1160.000574
S1146D1146HGacCac22AY.1210.000271
S1146D1146HGacCac22AY.200.000078
S1146D1146HGacCac22AY.3.10.000171
S1146D1146HGacCac22AY.570.001312
S1146D1146HGacCac22AY.590.001059
S1146D1146HGacCac22AY.750.000112
S1146D1146HGacCac22AY.9.10.000167
S1146D1146HGacCac22AY.9.20.000073
S1146D1146HGacCac22AY.98.10.000097
S1146D1146HGacCac22B.1.177.320.002699
S1146D1146HGacCac22B.1.3960.001411
S1146D1146HGacCac22B.1.4040.002604
S1146D1146HGacCac22B.1.4290.000047
S1146D1146HGacCac22B.1.6200.001892
S1146D1146HGacCac11A.2.50.000499
S1146D1146HGaCCaT11AT.10.005128
S1146D1146HGacCac11AY.1000.000046
S1146D1146HGacCac11AY.1190.000035
S1146D1146HGacCac11AY.160.00038
S1146D1146HGacCac11AY.300.000396
S1146D1146HGacCac11AY.330.000067
S1146D1146HGacCac11AY.340.000097
S1146D1146HGacCac11AY.4.2.10.000149
S1146D1146HGacCac11AY.450.000122
S1146D1146HGacCac11AY.460.000104
S1146D1146HGacCac11AY.5.30.000337
S1146D1146HGacCac11AY.5.40.000277
S1146D1146HGacCac11AY.530.000288
S1146D1146HGacCac11AY.670.000464
S1146D1146HGacCac11AY.780.001541
S1146D1146HGacCac11AY.910.00073
S1146D1146HGacCac11AY.920.000287
S1146D1146HGacCac11AY.950.000761
S1146D1146HGacCac11B.1.1.2050.003717
S1146D1146HGacCac11B.1.1.280.000311
S1146D1146HGacCac11B.1.1.4160.000905
S1146D1146HGacCac11B.1.1.500.000679
S1146D1146HGacCac11B.1.1.5230.001563
S1146D1146HGacCac11B.1.1490.003425
S1146D1146HGacCac11B.1.1600.000031
S1146D1146HGacCac11B.1.160.80.001289
S1146D1146HGacCac11B.1.177.120.000152
S1146D1146HGacCac11B.1.177.330.001645
S1146D1146HGacCac11B.1.177.480.003125
S1146D1146HGacCac11B.1.177.570.000281
S1146D1146HGacCac11B.1.177.750.001041
S1146D1146HGacCac11B.1.177.760.002494
S1146D1146HGacCac11B.1.2400.000216
S1146D1146HGacCac11B.1.258.220.002667
S1146D1146HGacCac11B.1.360.000146
S1146D1146HGacCac11B.1.3690.000285
S1146D1146HGacCac11B.1.5030.002488
S1146D1146HGacCac11B.1.5230.002451
S1146D1146HGacCac11B.1.5610.000397
S1146D1146HGacCac11B.1.5640.000426
S1146D1146HGacCac11B.1.5770.000687
S1146D1146HGacCac11B.1.6090.000479
S1146D1146HGacCac11B.1.617.10.000129
S1146D1146HGacCac11C.370.000116
S1146D1146HGacCac11D.20.000075
S1146D1146HGacCac11Q.40.000455
S1146D1146HGacCac11Q.70.001111
S1146D1146HGacCac11Q.80.000165
S1146D1146HGacCac11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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