CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = D111N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	111	D111N		nonsyn	Gat	Aat	1445	1442	0.997924	21893-21895
S	111	D111N		nonsyn	GaT	AaC	1445	3	0.00207612	21893-21895

Details of the mutation D111N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	111	D111N	Gat	Aat	1442	1445	All	0.000276
S	111	D111N	GaT	AaC	3	1445	All	0.000001
S	111	D111N	Gat	Aat	240	240	B.1.1	0.004354
S	111	D111N	Gat	Aat	209	209	B.1.1.7	0.000187
S	111	D111N	Gat	Aat	152	152	AY.4	0.000237
S	111	D111N	Gat	Aat	120	120	B.1.1.519	0.004765
S	111	D111N	Gat	Aat	119	119	B.1.1.222	0.024276
S	111	D111N	Gat	Aat	100	100	B.1.1.251	0.793651
S	111	D111N	Gat	Aat	81	81	B.1.2	0.000713
S	111	D111N	Gat	Aat	69	69	AY.44	0.00042
S	111	D111N	Gat	Aat	39	39	AY.43	0.000173
S	111	D111N	Gat	Aat	25	25	B.1.439	0.147929
S	111	D111N	Gat	Aat	24	24	B.1	0.00022
S	111	D111N	Gat	Aat	20	20	AY.42	0.000805
S	111	D111N	Gat	Aat	19	20	B.1.617.2	0.000072
S	111	D111N	GaT	AaC	1	20	B.1.617.2	0.000004
S	111	D111N	Gat	Aat	17	17	B.1.527	0.062963
S	111	D111N	Gat	Aat	17	17	B.1.621	0.001505
S	111	D111N	Gat	Aat	12	12	B.1.429	0.000282
S	111	D111N	Gat	Aat	11	11	B.1.160	0.000343
S	111	D111N	Gat	Aat	10	10	B.1.265	0.012706
S	111	D111N	Gat	Aat	9	9	AY.98.1	0.000436
S	111	D111N	Gat	Aat	7	7	AY.118	0.000439
S	111	D111N	Gat	Aat	6	6	AY.85	0.002563
S	111	D111N	Gat	Aat	5	5	AY.20	0.000194
S	111	D111N	Gat	Aat	5	5	AY.26	0.000142
S	111	D111N	Gat	Aat	5	5	AY.3	0.00005
S	111	D111N	Gat	Aat	5	5	AY.30	0.001979
S	111	D111N	Gat	Aat	5	5	AY.4.3	0.004209
S	111	D111N	Gat	Aat	5	5	B.1.1.216	0.004452
S	111	D111N	Gat	Aat	5	5	B.1.177.21	0.000382
S	111	D111N	Gat	Aat	4	4	AY.103	0.000025
S	111	D111N	Gat	Aat	3	4	AY.4.2	0.000065
S	111	D111N	GaT	AaC	1	4	AY.4.2	0.000022
S	111	D111N	Gat	Aat	4	4	B.1.177	0.000053
S	111	D111N	Gat	Aat	4	4	B.1.621.1	0.002023
S	111	D111N	Gat	Aat	4	4	C.37	0.000464
S	111	D111N	Gat	Aat	3	3	B.1.221	0.000213
S	111	D111N	Gat	Aat	3	3	B.1.351	0.000089
S	111	D111N	Gat	Aat	3	3	B.39	0.006993
S	111	D111N	Gat	Aat	2	2		0.111111
S	111	D111N	Gat	Aat	2	2	A	0.000774
S	111	D111N	Gat	Aat	2	2	A.1	0.000564
S	111	D111N	Gat	Aat	2	2	AY.102	0.000053
S	111	D111N	Gat	Aat	2	2	AY.29	0.000032
S	111	D111N	Gat	Aat	2	2	AY.47	0.000062
S	111	D111N	Gat	Aat	2	2	AY.71	0.00095
S	111	D111N	Gat	Aat	2	2	B.1.1.434	0.000697
S	111	D111N	Gat	Aat	2	2	B.1.258	0.000133
S	111	D111N	Gat	Aat	2	2	B.1.409	0.001563
S	111	D111N	Gat	Aat	2	2	B.1.637	0.000146
S	111	D111N	Gat	Aat	2	2	P.1	0.000032
S	111	D111N	Gat	Aat	1	1	A.23.1	0.000704
S	111	D111N	Gat	Aat	1	1	AM.4	0.003571
S	111	D111N	Gat	Aat	1	1	AY.10	0.00053
S	111	D111N	Gat	Aat	1	1	AY.100	0.000046
S	111	D111N	Gat	Aat	1	1	AY.109	0.00074
S	111	D111N	Gat	Aat	1	1	AY.116.1	0.000311
S	111	D111N	Gat	Aat	1	1	AY.120	0.000037
S	111	D111N	Gat	Aat	1	1	AY.13	0.000161
S	111	D111N	Gat	Aat	1	1	AY.2	0.000356
S	111	D111N	Gat	Aat	1	1	AY.23	0.00007
S	111	D111N	Gat	Aat	1	1	AY.23.1	0.000417
S	111	D111N	Gat	Aat	1	1	AY.25	0.000006
S	111	D111N	Gat	Aat	1	1	AY.4.5	0.000107
S	111	D111N	Gat	Aat	1	1	AY.46	0.000104
S	111	D111N	Gat	Aat	1	1	AY.46.4	0.000165
S	111	D111N	Gat	Aat	1	1	AY.5	0.000021
S	111	D111N	Gat	Aat	1	1	AY.59	0.00053
S	111	D111N	Gat	Aat	1	1	AY.6	0.000041
S	111	D111N	Gat	Aat	1	1	AY.62	0.000436
S	111	D111N	Gat	Aat	1	1	AY.69	0.000187
S	111	D111N	Gat	Aat	1	1	AY.7	0.000196
S	111	D111N	Gat	Aat	1	1	AY.79	0.001211
S	111	D111N	Gat	Aat	1	1	B.1.1.157	0.000913
S	111	D111N	Gat	Aat	1	1	B.1.1.159	0.004673
S	111	D111N	Gat	Aat	1	1	B.1.1.220	0.001859
S	111	D111N	Gat	Aat	1	1	B.1.1.28	0.000311
S	111	D111N	Gat	Aat	1	1	B.1.1.294	0.001266
S	111	D111N	Gat	Aat	1	1	B.1.1.306	0.000438
S	111	D111N	Gat	Aat	1	1	B.1.1.369	0.000446
S	111	D111N	Gat	Aat	1	1	B.1.1.486	0.001577
S	111	D111N	Gat	Aat	1	1	B.1.1.95	0.019608
S	111	D111N	Gat	Aat	1	1	B.1.177.85	0.005435
S	111	D111N	Gat	Aat	1	1	B.1.195	0.005025
S	111	D111N	Gat	Aat	1	1	B.1.232	0.000537
S	111	D111N	Gat	Aat	1	1	B.1.243	0.00007
S	111	D111N	Gat	Aat	1	1	B.1.298	0.002114
S	111	D111N	Gat	Aat	1	1	B.1.332	0.003497
S	111	D111N	Gat	Aat	1	1	B.1.349	0.000715
S	111	D111N	Gat	Aat	1	1	B.1.378	0.006849
S	111	D111N	Gat	Aat	1	1	B.1.396	0.000706
S	111	D111N	Gat	Aat	1	1	B.1.468	0.005714
S	111	D111N	Gat	Aat	1	1	B.1.517	0.000427
S	111	D111N	Gat	Aat	1	1	B.1.577	0.000687
S	111	D111N	Gat	Aat	1	1	B.1.596	0.000087
S	111	D111N	GaT	AaC	1	1	B.1.617.1	0.000129
S	111	D111N	Gat	Aat	1	1	B.1.9	0.006173
S	111	D111N	Gat	Aat	1	1	B.1.94	0.027027
S	111	D111N	Gat	Aat	1	1	C.1.2	0.004255
S	111	D111N	Gat	Aat	1	1	P.1.14	0.000048
S	111	D111N	Gat	Aat	1	1	P.2	0.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.