CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 111 | D111N | nonsyn | Gat | Aat | 1445 | 1442 | 0.997924 | 21893-21895 | |
S | 111 | D111N | nonsyn | GaT | AaC | 1445 | 3 | 0.00207612 | 21893-21895 |
Details of the mutation D111N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 111 | D111N | Gat | Aat | 1442 | 1445 | All | 0.000276 |
S | 111 | D111N | GaT | AaC | 3 | 1445 | All | 0.000001 |
S | 111 | D111N | Gat | Aat | 240 | 240 | B.1.1 | 0.004354 |
S | 111 | D111N | Gat | Aat | 209 | 209 | B.1.1.7 | 0.000187 |
S | 111 | D111N | Gat | Aat | 152 | 152 | AY.4 | 0.000237 |
S | 111 | D111N | Gat | Aat | 120 | 120 | B.1.1.519 | 0.004765 |
S | 111 | D111N | Gat | Aat | 119 | 119 | B.1.1.222 | 0.024276 |
S | 111 | D111N | Gat | Aat | 100 | 100 | B.1.1.251 | 0.793651 |
S | 111 | D111N | Gat | Aat | 81 | 81 | B.1.2 | 0.000713 |
S | 111 | D111N | Gat | Aat | 69 | 69 | AY.44 | 0.00042 |
S | 111 | D111N | Gat | Aat | 39 | 39 | AY.43 | 0.000173 |
S | 111 | D111N | Gat | Aat | 25 | 25 | B.1.439 | 0.147929 |
S | 111 | D111N | Gat | Aat | 24 | 24 | B.1 | 0.00022 |
S | 111 | D111N | Gat | Aat | 20 | 20 | AY.42 | 0.000805 |
S | 111 | D111N | Gat | Aat | 19 | 20 | B.1.617.2 | 0.000072 |
S | 111 | D111N | GaT | AaC | 1 | 20 | B.1.617.2 | 0.000004 |
S | 111 | D111N | Gat | Aat | 17 | 17 | B.1.527 | 0.062963 |
S | 111 | D111N | Gat | Aat | 17 | 17 | B.1.621 | 0.001505 |
S | 111 | D111N | Gat | Aat | 12 | 12 | B.1.429 | 0.000282 |
S | 111 | D111N | Gat | Aat | 11 | 11 | B.1.160 | 0.000343 |
S | 111 | D111N | Gat | Aat | 10 | 10 | B.1.265 | 0.012706 |
S | 111 | D111N | Gat | Aat | 9 | 9 | AY.98.1 | 0.000436 |
S | 111 | D111N | Gat | Aat | 7 | 7 | AY.118 | 0.000439 |
S | 111 | D111N | Gat | Aat | 6 | 6 | AY.85 | 0.002563 |
S | 111 | D111N | Gat | Aat | 5 | 5 | AY.20 | 0.000194 |
S | 111 | D111N | Gat | Aat | 5 | 5 | AY.26 | 0.000142 |
S | 111 | D111N | Gat | Aat | 5 | 5 | AY.3 | 0.00005 |
S | 111 | D111N | Gat | Aat | 5 | 5 | AY.30 | 0.001979 |
S | 111 | D111N | Gat | Aat | 5 | 5 | AY.4.3 | 0.004209 |
S | 111 | D111N | Gat | Aat | 5 | 5 | B.1.1.216 | 0.004452 |
S | 111 | D111N | Gat | Aat | 5 | 5 | B.1.177.21 | 0.000382 |
S | 111 | D111N | Gat | Aat | 4 | 4 | AY.103 | 0.000025 |
S | 111 | D111N | Gat | Aat | 3 | 4 | AY.4.2 | 0.000065 |
S | 111 | D111N | GaT | AaC | 1 | 4 | AY.4.2 | 0.000022 |
S | 111 | D111N | Gat | Aat | 4 | 4 | B.1.177 | 0.000053 |
S | 111 | D111N | Gat | Aat | 4 | 4 | B.1.621.1 | 0.002023 |
S | 111 | D111N | Gat | Aat | 4 | 4 | C.37 | 0.000464 |
S | 111 | D111N | Gat | Aat | 3 | 3 | B.1.221 | 0.000213 |
S | 111 | D111N | Gat | Aat | 3 | 3 | B.1.351 | 0.000089 |
S | 111 | D111N | Gat | Aat | 3 | 3 | B.39 | 0.006993 |
S | 111 | D111N | Gat | Aat | 2 | 2 | 0.111111 | |
S | 111 | D111N | Gat | Aat | 2 | 2 | A | 0.000774 |
S | 111 | D111N | Gat | Aat | 2 | 2 | A.1 | 0.000564 |
S | 111 | D111N | Gat | Aat | 2 | 2 | AY.102 | 0.000053 |
S | 111 | D111N | Gat | Aat | 2 | 2 | AY.29 | 0.000032 |
S | 111 | D111N | Gat | Aat | 2 | 2 | AY.47 | 0.000062 |
S | 111 | D111N | Gat | Aat | 2 | 2 | AY.71 | 0.00095 |
S | 111 | D111N | Gat | Aat | 2 | 2 | B.1.1.434 | 0.000697 |
S | 111 | D111N | Gat | Aat | 2 | 2 | B.1.258 | 0.000133 |
S | 111 | D111N | Gat | Aat | 2 | 2 | B.1.409 | 0.001563 |
S | 111 | D111N | Gat | Aat | 2 | 2 | B.1.637 | 0.000146 |
S | 111 | D111N | Gat | Aat | 2 | 2 | P.1 | 0.000032 |
S | 111 | D111N | Gat | Aat | 1 | 1 | A.23.1 | 0.000704 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AM.4 | 0.003571 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.10 | 0.00053 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.100 | 0.000046 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.109 | 0.00074 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.116.1 | 0.000311 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.120 | 0.000037 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.13 | 0.000161 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.2 | 0.000356 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.23 | 0.00007 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.23.1 | 0.000417 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.25 | 0.000006 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.4.5 | 0.000107 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.46 | 0.000104 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.46.4 | 0.000165 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.5 | 0.000021 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.59 | 0.00053 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.6 | 0.000041 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.62 | 0.000436 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.69 | 0.000187 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.7 | 0.000196 |
S | 111 | D111N | Gat | Aat | 1 | 1 | AY.79 | 0.001211 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.157 | 0.000913 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.159 | 0.004673 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.220 | 0.001859 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.28 | 0.000311 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.294 | 0.001266 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.306 | 0.000438 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.369 | 0.000446 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.486 | 0.001577 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.1.95 | 0.019608 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.177.85 | 0.005435 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.195 | 0.005025 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.232 | 0.000537 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.243 | 0.00007 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.298 | 0.002114 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.332 | 0.003497 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.349 | 0.000715 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.378 | 0.006849 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.396 | 0.000706 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.468 | 0.005714 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.517 | 0.000427 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.577 | 0.000687 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.596 | 0.000087 |
S | 111 | D111N | GaT | AaC | 1 | 1 | B.1.617.1 | 0.000129 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.9 | 0.006173 |
S | 111 | D111N | Gat | Aat | 1 | 1 | B.1.94 | 0.027027 |
S | 111 | D111N | Gat | Aat | 1 | 1 | C.1.2 | 0.004255 |
S | 111 | D111N | Gat | Aat | 1 | 1 | P.1.14 | 0.000048 |
S | 111 | D111N | Gat | Aat | 1 | 1 | P.2 | 0.000187 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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