CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : Mut = A924S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	924	A924S		nonsyn	Gcc	Tcc	943	920	0.97561	24332-24334
S	924	A924S		nonsyn	GcC	TcT	943	22	0.0233298	24332-24334
S	924	A924S		nonsyn	GcC	TcA	943	1	0.00106045	24332-24334

Details of the mutation A924S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	924	A924S	Gcc	Tcc	920	943	All	0.000176
S	924	A924S	GcC	TcT	22	943	All	0.000004
S	924	A924S	GcC	TcA	1	943	All	0
S	924	A924S	Gcc	Tcc	167	167	B.1.617.2	0.000629
S	924	A924S	Gcc	Tcc	104	104	AY.43	0.000461
S	924	A924S	Gcc	Tcc	76	77	AY.4	0.000118
S	924	A924S	GcC	TcT	1	77	AY.4	0.000002
S	924	A924S	Gcc	Tcc	73	73	AY.4.2	0.001583
S	924	A924S	Gcc	Tcc	46	46	AY.36	0.006818
S	924	A924S	Gcc	Tcc	46	46	AY.39.1	0.001822
S	924	A924S	Gcc	Tcc	41	41	AY.103	0.000255
S	924	A924S	Gcc	Tcc	38	38	AY.5	0.000785
S	924	A924S	Gcc	Tcc	32	32	AY.44	0.000195
S	924	A924S	Gcc	Tcc	29	29	B.1.1.7	0.000026
S	924	A924S	Gcc	Tcc	23	23	AY.100	0.001058
S	924	A924S	GcC	TcT	21	23	B.1.177	0.000277
S	924	A924S	Gcc	Tcc	2	23	B.1.177	0.000026
S	924	A924S	Gcc	Tcc	12	12	AY.121	0.001624
S	924	A924S	Gcc	Tcc	10	10	B.1	0.000092
S	924	A924S	Gcc	Tcc	9	9	AY.119	0.000318
S	924	A924S	Gcc	Tcc	9	9	AY.29	0.000142
S	924	A924S	Gcc	Tcc	9	9	B.1.2	0.000079
S	924	A924S	Gcc	Tcc	9	9	B.1.596	0.000784
S	924	A924S	Gcc	Tcc	8	8	B.1.1.284	0.000859
S	924	A924S	Gcc	Tcc	8	8	B.1.561	0.003176
S	924	A924S	Gcc	Tcc	7	7	AY.116	0.002007
S	924	A924S	Gcc	Tcc	7	7	AY.20	0.000272
S	924	A924S	Gcc	Tcc	7	7	AY.25	0.000042
S	924	A924S	Gcc	Tcc	7	7	AY.3.1	0.000597
S	924	A924S	Gcc	Tcc	6	6	AY.102	0.000159
S	924	A924S	Gcc	Tcc	6	6	AY.117	0.000507
S	924	A924S	Gcc	Tcc	6	6	AY.39	0.000148
S	924	A924S	Gcc	Tcc	6	6	B.1.427	0.000303
S	924	A924S	Gcc	Tcc	5	5	AY.23	0.000349
S	924	A924S	Gcc	Tcc	5	5	AY.74	0.000578
S	924	A924S	Gcc	Tcc	5	5	B.1.160	0.000156
S	924	A924S	Gcc	Tcc	5	5	B.1.351	0.000149
S	924	A924S	Gcc	Tcc	5	5	B.1.617.1	0.000645
S	924	A924S	Gcc	Tcc	4	4	AY.120	0.000149
S	924	A924S	Gcc	Tcc	4	4	AY.9.2	0.000147
S	924	A924S	Gcc	Tcc	4	4	B.1.1	0.000073
S	924	A924S	Gcc	Tcc	4	4	B.1.1.298	0.003448
S	924	A924S	Gcc	Tcc	4	4	B.1.1.347	0.072727
S	924	A924S	Gcc	Tcc	2	3		0.111111
S	924	A924S	GcC	TcA	1	3		0.055556
S	924	A924S	Gcc	Tcc	3	3	AY.98.1	0.000145
S	924	A924S	Gcc	Tcc	3	3	C.39	0.056604
S	924	A924S	Gcc	Tcc	2	2	AY.34	0.000194
S	924	A924S	Gcc	Tcc	2	2	AY.37	0.000632
S	924	A924S	Gcc	Tcc	2	2	AY.46.6	0.000144
S	924	A924S	Gcc	Tcc	2	2	AY.47	0.000062
S	924	A924S	Gcc	Tcc	2	2	AY.99	0.002099
S	924	A924S	Gcc	Tcc	2	2	B.1.1.519	0.000079
S	924	A924S	Gcc	Tcc	2	2	B.1.258	0.000133
S	924	A924S	Gcc	Tcc	2	2	B.1.320	0.002491
S	924	A924S	Gcc	Tcc	2	2	B.1.36.17	0.000988
S	924	A924S	Gcc	Tcc	2	2	B.1.429	0.000047
S	924	A924S	Gcc	Tcc	1	1	AY.111	0.000183
S	924	A924S	Gcc	Tcc	1	1	AY.114	0.000231
S	924	A924S	Gcc	Tcc	1	1	AY.116.1	0.000311
S	924	A924S	Gcc	Tcc	1	1	AY.2	0.000356
S	924	A924S	Gcc	Tcc	1	1	AY.26	0.000028
S	924	A924S	Gcc	Tcc	1	1	AY.3	0.00001
S	924	A924S	Gcc	Tcc	1	1	AY.33	0.000067
S	924	A924S	Gcc	Tcc	1	1	AY.4.2.1	0.000149
S	924	A924S	Gcc	Tcc	1	1	AY.4.5	0.000107
S	924	A924S	Gcc	Tcc	1	1	AY.46.4	0.000165
S	924	A924S	Gcc	Tcc	1	1	AY.46.5	0.000198
S	924	A924S	Gcc	Tcc	1	1	AY.53	0.000288
S	924	A924S	Gcc	Tcc	1	1	AY.56	0.001605
S	924	A924S	Gcc	Tcc	1	1	AY.6	0.000041
S	924	A924S	Gcc	Tcc	1	1	AY.7	0.000196
S	924	A924S	Gcc	Tcc	1	1	AY.83	0.001724
S	924	A924S	Gcc	Tcc	1	1	AY.87	0.000833
S	924	A924S	Gcc	Tcc	1	1	AY.9	0.000068
S	924	A924S	Gcc	Tcc	1	1	AY.92	0.000287
S	924	A924S	Gcc	Tcc	1	1	AY.96	0.002075
S	924	A924S	Gcc	Tcc	1	1	AY.98	0.000079
S	924	A924S	Gcc	Tcc	1	1	B.1.1.216	0.00089
S	924	A924S	Gcc	Tcc	1	1	B.1.1.312	0.001912
S	924	A924S	Gcc	Tcc	1	1	B.1.1.317	0.000412
S	924	A924S	Gcc	Tcc	1	1	B.1.1.432	0.001266
S	924	A924S	Gcc	Tcc	1	1	B.1.1.5	0.008333
S	924	A924S	Gcc	Tcc	1	1	B.1.1.70	0.000341
S	924	A924S	Gcc	Tcc	1	1	B.1.177.77	0.000726
S	924	A924S	Gcc	Tcc	1	1	B.1.195	0.005025
S	924	A924S	Gcc	Tcc	1	1	B.1.218	0.005155
S	924	A924S	Gcc	Tcc	1	1	B.1.221.1	0.002907
S	924	A924S	Gcc	Tcc	1	1	B.1.240	0.000216
S	924	A924S	Gcc	Tcc	1	1	B.1.36	0.000146
S	924	A924S	Gcc	Tcc	1	1	B.1.36.29	0.000517
S	924	A924S	Gcc	Tcc	1	1	B.1.525	0.000113
S	924	A924S	Gcc	Tcc	1	1	B.1.526	0.000024
S	924	A924S	Gcc	Tcc	1	1	B.1.575	0.000303
S	924	A924S	Gcc	Tcc	1	1	B.1.582	0.000491
S	924	A924S	Gcc	Tcc	1	1	B.1.588	0.00091
S	924	A924S	Gcc	Tcc	1	1	B.3	0.000831
S	924	A924S	Gcc	Tcc	1	1	D.2	0.000075
S	924	A924S	Gcc	Tcc	1	1	P.1	0.000016
S	924	A924S	Gcc	Tcc	1	1	P.1.9	0.004808
S	924	A924S	Gcc	Tcc	1	1	Q.1	0.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.