CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 922 | L922F | nonsyn | ttG | ttT | 1653 | 1354 | 0.819117 | 24326-24328 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 922 | L922F | ttG | ttT | 1354 | 1653 | All | 0.000259 |
S | 922 | L922F | ttG | ttT | 378 | 466 | B.1.1.7 | 0.000338 |
S | 922 | L922F | ttG | ttT | 196 | 215 | AY.4 | 0.000305 |
S | 922 | L922F | ttG | ttT | 109 | 124 | AY.43 | 0.000483 |
S | 922 | L922F | ttG | ttT | 100 | 115 | B.1.617.2 | 0.000377 |
S | 922 | L922F | ttG | ttT | 55 | 71 | AY.25 | 0.000331 |
S | 922 | L922F | ttG | ttT | 42 | 56 | AY.44 | 0.000256 |
S | 922 | L922F | ttG | ttT | 22 | 50 | AY.20 | 0.000855 |
S | 922 | L922F | ttG | ttT | 27 | 31 | AY.103 | 0.000168 |
S | 922 | L922F | ttG | ttT | 27 | 27 | AY.3 | 0.000269 |
S | 922 | L922F | ttG | ttT | 24 | 24 | AY.111 | 0.004396 |
S | 922 | L922F | ttG | ttT | 18 | 22 | B.1 | 0.000165 |
S | 922 | L922F | ttG | ttT | 7 | 20 | AY.39 | 0.000173 |
S | 922 | L922F | ttG | ttT | 11 | 20 | AY.4.2 | 0.000239 |
S | 922 | L922F | ttG | ttT | 11 | 15 | AY.29 | 0.000174 |
S | 922 | L922F | ttG | ttT | 13 | 13 | AY.119 | 0.000459 |
S | 922 | L922F | ttG | ttT | 13 | 13 | AY.98.1 | 0.00063 |
S | 922 | L922F | ttG | ttT | 10 | 13 | B.1.2 | 0.000088 |
S | 922 | L922F | ttG | ttT | 12 | 12 | AY.102 | 0.000318 |
S | 922 | L922F | ttG | ttT | 9 | 11 | B.1.1.519 | 0.000357 |
S | 922 | L922F | ttG | ttT | 9 | 9 | AY.39.1 | 0.000357 |
S | 922 | L922F | ttG | ttT | 9 | 9 | AY.47 | 0.00028 |
S | 922 | L922F | ttG | ttT | 9 | 9 | AY.68 | 0.002464 |
S | 922 | L922F | ttG | ttT | 3 | 9 | B.1.1 | 0.000054 |
S | 922 | L922F | ttG | ttT | 8 | 9 | B.1.351 | 0.000238 |
S | 922 | L922F | ttG | ttT | 9 | 9 | P.1 | 0.000142 |
S | 922 | L922F | ttG | ttT | 8 | 8 | B | 0.001022 |
S | 922 | L922F | ttG | ttT | 7 | 8 | B.1.429 | 0.000165 |
S | 922 | L922F | ttG | ttT | 7 | 7 | B.1.233 | 0.098592 |
S | 922 | L922F | ttG | ttT | 5 | 6 | AY.23 | 0.000349 |
S | 922 | L922F | ttG | ttT | 6 | 6 | B.1.160 | 0.000187 |
S | 922 | L922F | ttG | ttT | 6 | 6 | B.1.177 | 0.000079 |
S | 922 | L922F | ttG | ttT | 5 | 5 | AY.114 | 0.001156 |
S | 922 | L922F | ttG | ttT | 3 | 5 | AY.120 | 0.000112 |
S | 922 | L922F | ttG | ttT | 5 | 5 | AY.14 | 0.00044 |
S | 922 | L922F | ttG | ttT | 5 | 5 | AY.27 | 0.000324 |
S | 922 | L922F | ttG | ttT | 5 | 5 | AY.42 | 0.000201 |
S | 922 | L922F | ttG | ttT | 5 | 5 | AY.46.6 | 0.000361 |
S | 922 | L922F | ttG | ttT | 5 | 5 | AY.99.2 | 0.000461 |
S | 922 | L922F | ttG | ttT | 5 | 5 | B.1.1.207 | 0.00591 |
S | 922 | L922F | ttG | ttT | 5 | 5 | B.1.1.216 | 0.004452 |
S | 922 | L922F | ttG | ttT | 5 | 5 | B.1.503 | 0.012438 |
S | 922 | L922F | ttG | ttT | 5 | 5 | B.1.526 | 0.000118 |
S | 922 | L922F | ttG | ttT | 4 | 5 | B.1.596 | 0.000349 |
S | 922 | L922F | ttG | ttT | 5 | 5 | B.1.621 | 0.000443 |
S | 922 | L922F | ttG | ttT | 4 | 4 | A.21 | 0.01108 |
S | 922 | L922F | ttG | ttT | 4 | 4 | AY.117 | 0.000338 |
S | 922 | L922F | ttG | ttT | 4 | 4 | AY.121 | 0.000541 |
S | 922 | L922F | ttG | ttT | 4 | 4 | AY.46 | 0.000416 |
S | 922 | L922F | ttG | ttT | 1 | 4 | AY.75 | 0.000056 |
S | 922 | L922F | ttG | ttT | 3 | 4 | B.1.1.214 | 0.000166 |
S | 922 | L922F | ttG | ttT | 4 | 4 | C.36.3 | 0.002269 |
S | 922 | L922F | ttG | ttT | 2 | 4 | P.1.14 | 0.000096 |
S | 922 | L922F | ttG | ttT | 4 | 4 | R.1 | 0.00036 |
S | 922 | L922F | ttG | ttT | 3 | 3 | AY.113 | 0.000427 |
S | 922 | L922F | ttG | ttT | 1 | 3 | AY.33 | 0.000067 |
S | 922 | L922F | ttG | ttT | 3 | 3 | AY.34 | 0.000291 |
S | 922 | L922F | ttG | ttT | 2 | 3 | AY.36 | 0.000296 |
S | 922 | L922F | ttG | ttT | 2 | 3 | AY.61 | 0.00021 |
S | 922 | L922F | ttG | ttT | 3 | 3 | AY.74 | 0.000347 |
S | 922 | L922F | ttG | ttT | 3 | 3 | AY.9 | 0.000203 |
S | 922 | L922F | ttG | ttT | 3 | 3 | B.1.1.263 | 0.004673 |
S | 922 | L922F | ttG | ttT | 3 | 3 | B.1.22 | 0.003953 |
S | 922 | L922F | ttG | ttT | 3 | 3 | B.1.36 | 0.000438 |
S | 922 | L922F | ttG | ttT | 3 | 3 | B.1.575 | 0.00091 |
S | 922 | L922F | ttG | ttT | 2 | 3 | B.1.617.1 | 0.000258 |
S | 922 | L922F | ttG | ttT | 3 | 3 | P.2 | 0.00056 |
S | 922 | L922F | ttG | ttT | 1 | 2 | AY.116.1 | 0.000311 |
S | 922 | L922F | ttG | ttT | 1 | 2 | AY.24 | 0.000431 |
S | 922 | L922F | ttG | ttT | 1 | 2 | AY.26 | 0.000028 |
S | 922 | L922F | ttG | ttT | 2 | 2 | AY.35 | 0.000466 |
S | 922 | L922F | ttG | ttT | 1 | 2 | AY.6 | 0.000041 |
S | 922 | L922F | ttG | ttT | 1 | 2 | B.1.1.306 | 0.000438 |
S | 922 | L922F | ttG | ttT | 2 | 2 | B.1.221 | 0.000142 |
S | 922 | L922F | ttG | ttT | 1 | 1 | 0.055556 | |
S | 922 | L922F | ttG | ttT | 1 | 1 | A.2.4 | 0.003367 |
S | 922 | L922F | ttG | ttT | 1 | 1 | A.25 | 0.018182 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AB.1 | 0.008197 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AE.8 | 0.000489 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.100 | 0.000046 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.101 | 0.00049 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.45 | 0.000122 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.46.1 | 0.001027 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.46.3 | 0.000934 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.46.4 | 0.000165 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.5 | 0.000021 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.5.4 | 0.000277 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.55 | 0.000917 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.69 | 0.000187 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.7.1 | 0.000113 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.70 | 0.000209 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.79 | 0.001211 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.84 | 0.000437 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.9.2 | 0.000037 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.92 | 0.000287 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.97 | 0.001701 |
S | 922 | L922F | ttG | ttT | 1 | 1 | AY.98 | 0.000079 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.1.157 | 0.000913 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.1.307 | 0.002532 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.1.318 | 0.000302 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.1.372 | 0.000689 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.1.440 | 0.011765 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.1.464 | 0.001473 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.177.32 | 0.00135 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.177.56 | 0.000668 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.189 | 0.004292 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.210 | 0.002132 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.218 | 0.005155 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.234 | 0.000132 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.240 | 0.000216 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.243 | 0.00007 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.301 | 0.005917 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.389 | 0.001002 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.399 | 0.001934 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.426 | 0.001009 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.582 | 0.000491 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.609 | 0.000479 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.628 | 0.000352 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.1.9 | 0.006173 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.40 | 0.000364 |
S | 922 | L922F | ttG | ttT | 1 | 1 | B.6 | 0.00091 |
S | 922 | L922F | ttG | ttT | 1 | 1 | C.37 | 0.000116 |
S | 922 | L922F | ttG | ttT | 1 | 1 | D.2 | 0.000075 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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