CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 892 | A892V | nonsyn | gCt | gTt | 2250 | 2246 | 0.998222 | 24236-24238 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 892 | A892V | gCt | gTt | 2246 | 2250 | All | 0.00043 |
S | 892 | A892V | gCt | gTt | 1188 | 1188 | B.1.1.7 | 0.001064 |
S | 892 | A892V | gCt | gTt | 106 | 106 | B.1.617.2 | 0.000399 |
S | 892 | A892V | gCt | gTt | 100 | 100 | AY.4 | 0.000156 |
S | 892 | A892V | gCt | gTt | 50 | 50 | AY.43 | 0.000222 |
S | 892 | A892V | gCt | gTt | 43 | 43 | AY.103 | 0.000267 |
S | 892 | A892V | gCt | gTt | 43 | 43 | B.1.363 | 0.558442 |
S | 892 | A892V | gCt | gTt | 33 | 33 | AY.25 | 0.000198 |
S | 892 | A892V | gCt | gTt | 32 | 32 | AY.44 | 0.000195 |
S | 892 | A892V | gCt | gTt | 30 | 30 | AY.3 | 0.000298 |
S | 892 | A892V | gCt | gTt | 27 | 27 | AY.6 | 0.00111 |
S | 892 | A892V | gCt | gTt | 25 | 25 | AY.9.2 | 0.000918 |
S | 892 | A892V | gCt | gTt | 22 | 22 | AY.47 | 0.000684 |
S | 892 | A892V | gCt | gTt | 22 | 22 | B.1 | 0.000202 |
S | 892 | A892V | gCt | gTt | 20 | 20 | P.1 | 0.000315 |
S | 892 | A892V | gCt | gTt | 19 | 19 | AY.4.2 | 0.000412 |
S | 892 | A892V | gCt | gTt | 19 | 19 | AY.61 | 0.001991 |
S | 892 | A892V | gCt | gTt | 17 | 17 | B.1.2 | 0.00015 |
S | 892 | A892V | gCt | gTt | 16 | 16 | AY.29 | 0.000252 |
S | 892 | A892V | gCt | gTt | 16 | 16 | AY.39 | 0.000395 |
S | 892 | A892V | gCt | gTt | 15 | 15 | B.1.1 | 0.000272 |
S | 892 | A892V | gCt | gTt | 14 | 14 | B.1.177 | 0.000184 |
S | 892 | A892V | gCt | gTt | 14 | 14 | P.1.14 | 0.000669 |
S | 892 | A892V | gCt | gTt | 13 | 13 | B.1.564.1 | 0.020505 |
S | 892 | A892V | gCt | gTt | 12 | 12 | AY.26 | 0.00034 |
S | 892 | A892V | gCt | gTt | 11 | 11 | B.1.526 | 0.000259 |
S | 892 | A892V | gCt | gTt | 10 | 10 | AY.117 | 0.000845 |
S | 892 | A892V | gCt | gTt | 10 | 10 | AY.5 | 0.000206 |
S | 892 | A892V | gCt | gTt | 9 | 9 | AY.119 | 0.000318 |
S | 892 | A892V | gCt | gTt | 9 | 9 | AY.20 | 0.00035 |
S | 892 | A892V | gCt | gTt | 9 | 9 | B.1.351 | 0.000268 |
S | 892 | A892V | gCt | gTt | 8 | 8 | AY.59 | 0.004237 |
S | 892 | A892V | gCt | gTt | 8 | 8 | R.1 | 0.00072 |
S | 892 | A892V | gCt | gTt | 7 | 7 | AY.106 | 0.002344 |
S | 892 | A892V | gCt | gTt | 7 | 7 | AY.120 | 0.00026 |
S | 892 | A892V | gCt | gTt | 7 | 7 | B.1.429 | 0.000165 |
S | 892 | A892V | gCt | gTt | 7 | 7 | Q.1 | 0.000884 |
S | 892 | A892V | gCt | gTt | 6 | 6 | AY.29.1 | 0.001323 |
S | 892 | A892V | gCt | gTt | 6 | 6 | B.1.1.294 | 0.007595 |
S | 892 | A892V | gCt | gTt | 6 | 6 | B.1.1.519 | 0.000238 |
S | 892 | A892V | gCt | gTt | 6 | 6 | B.1.160 | 0.000187 |
S | 892 | A892V | gCt | gTt | 6 | 6 | B.1.177.73 | 0.003398 |
S | 892 | A892V | gCt | gTt | 5 | 5 | AY.102 | 0.000133 |
S | 892 | A892V | gCt | gTt | 5 | 5 | AY.4.5 | 0.000537 |
S | 892 | A892V | gCt | gTt | 5 | 5 | AY.42 | 0.000201 |
S | 892 | A892V | gCt | gTt | 5 | 5 | AY.98 | 0.000395 |
S | 892 | A892V | gCt | gTt | 5 | 5 | Q.3 | 0.000725 |
S | 892 | A892V | gCt | gTt | 4 | 4 | A | 0.001548 |
S | 892 | A892V | gCt | gTt | 4 | 4 | AY.100 | 0.000184 |
S | 892 | A892V | gCt | gTt | 4 | 4 | AY.19 | 0.004561 |
S | 892 | A892V | gCt | gTt | 4 | 4 | AY.23 | 0.000279 |
S | 892 | A892V | gCt | gTt | 4 | 4 | AY.41 | 0.001176 |
S | 892 | A892V | gCt | gTt | 4 | 4 | AY.48 | 0.00186 |
S | 892 | A892V | gCt | gTt | 4 | 4 | B.1.177.21 | 0.000306 |
S | 892 | A892V | gCt | gTt | 4 | 4 | Q.8 | 0.00066 |
S | 892 | A892V | gCt | gTt | 3 | 3 | AY.39.1 | 0.000119 |
S | 892 | A892V | gCt | gTt | 3 | 3 | AY.46.6 | 0.000217 |
S | 892 | A892V | gCt | gTt | 3 | 3 | AY.54 | 0.000286 |
S | 892 | A892V | gCt | gTt | 3 | 3 | AY.75.1 | 0.000541 |
S | 892 | A892V | gCt | gTt | 3 | 3 | AY.99.2 | 0.000276 |
S | 892 | A892V | gCt | gTt | 3 | 3 | B.1.221 | 0.000213 |
S | 892 | A892V | gCt | gTt | 3 | 3 | B.1.258 | 0.0002 |
S | 892 | A892V | gCt | gTt | 3 | 3 | B.1.628 | 0.001057 |
S | 892 | A892V | gCt | gTt | 3 | 3 | D.2 | 0.000225 |
S | 892 | A892V | gCt | gTt | 3 | 3 | Q.4 | 0.001364 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.121 | 0.000271 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.27 | 0.000129 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.3.1 | 0.000171 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.33 | 0.000134 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.7.1 | 0.000225 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.8 | 0.001212 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.9.1 | 0.000167 |
S | 892 | A892V | gCt | gTt | 2 | 2 | AY.98.1 | 0.000097 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.1.161 | 0.007067 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.177.12 | 0.000303 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.177.4 | 0.000422 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.177.57 | 0.000562 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.177.86 | 0.000367 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.214.2 | 0.001199 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.36 | 0.000292 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.438.1 | 0.000215 |
S | 892 | A892V | gCt | gTt | 2 | 2 | B.1.621.1 | 0.001012 |
S | 892 | A892V | gCt | gTt | 2 | 2 | P.2 | 0.000373 |
S | 892 | A892V | gCt | gTt | 1 | 1 | A.21 | 0.00277 |
S | 892 | A892V | gCt | gTt | 1 | 1 | A.28 | 0.002646 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AE.8 | 0.000489 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AU.1 | 0.001266 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.105 | 0.000643 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.111 | 0.000183 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.113 | 0.000142 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.114 | 0.000231 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.118 | 0.000063 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.12 | 0.000316 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.16.1 | 0.00047 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.21 | 0.001898 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.23.1 | 0.000417 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.34 | 0.000097 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.46 | 0.000104 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.46.3 | 0.000934 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.5.4 | 0.000277 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.55 | 0.000917 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.57 | 0.000656 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.62 | 0.000436 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.64 | 0.000595 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.65 | 0.000533 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.69 | 0.000187 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.7 | 0.000196 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.75 | 0.000056 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.84 | 0.000437 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.86 | 0.00083 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.91 | 0.00073 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AY.94 | 0.000443 |
S | 892 | A892V | gCt | gTt | 1 | 1 | AZ.4 | 0.003356 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B | 0.000128 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.121 | 0.002427 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.164 | 0.005155 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.165 | 0.015385 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.222 | 0.000204 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.243 | 0.004082 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.25 | 0.000569 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.284 | 0.000107 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.317 | 0.000412 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.344 | 0.010753 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.372 | 0.000689 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.385 | 0.004464 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.39 | 0.00051 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.416 | 0.000905 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.419 | 0.007407 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.46 | 0.004367 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.523 | 0.001563 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.1.92 | 0.033333 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.160.16 | 0.000929 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.160.26 | 0.002421 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.160.32 | 0.004292 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.177.10 | 0.000878 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.177.15 | 0.000631 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.177.31 | 0.011494 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.177.6 | 0.000977 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.177.7 | 0.000165 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.232 | 0.000537 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.243 | 0.00007 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.260 | 0.003344 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.320 | 0.001245 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.334 | 0.018182 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.351.3 | 0.000876 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.351.5 | 0.0006 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.36.1 | 0.00114 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.36.17 | 0.000494 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.36.29 | 0.000517 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.390 | 0.010638 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.404 | 0.001302 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.422 | 0.000812 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.427 | 0.00005 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.456 | 0.003268 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.466.2 | 0.000391 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.474 | 0.001901 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.524 | 0.001406 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.576 | 0.000907 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.595 | 0.000261 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.596 | 0.000087 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.602 | 0.006536 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.609 | 0.000479 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.612 | 0.002653 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.617.1 | 0.000129 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.619.1 | 0.000641 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.620 | 0.000946 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.621 | 0.000089 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.623 | 0.000536 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.1.637 | 0.000073 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.29 | 0.003509 |
S | 892 | A892V | gCt | gTt | 1 | 1 | B.40 | 0.000364 |
S | 892 | A892V | gCt | gTt | 1 | 1 | C.16 | 0.00106 |
S | 892 | A892V | gCt | gTt | 1 | 1 | C.35 | 0.000774 |
S | 892 | A892V | gCt | gTt | 1 | 1 | C.36.3 | 0.000567 |
S | 892 | A892V | gCt | gTt | 1 | 1 | C.37 | 0.000116 |
S | 892 | A892V | gCt | gTt | 1 | 1 | P.1.1 | 0.000318 |
S | 892 | A892V | gCt | gTt | 1 | 1 | P.1.10 | 0.000269 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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