CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 884 | S884F | nonsyn | tCt | tTt | 1096 | 1096 | 1 | 24212-24214 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 884 | S884F | tCt | tTt | 1096 | 1096 | All | 0.00021 |
S | 884 | S884F | tCt | tTt | 363 | 363 | B.1.1.7 | 0.000325 |
S | 884 | S884F | tCt | tTt | 125 | 125 | AY.4 | 0.000195 |
S | 884 | S884F | tCt | tTt | 46 | 46 | B.1.177 | 0.000606 |
S | 884 | S884F | tCt | tTt | 36 | 36 | B.1.2 | 0.000317 |
S | 884 | S884F | tCt | tTt | 30 | 30 | B.1 | 0.000275 |
S | 884 | S884F | tCt | tTt | 23 | 23 | AY.25 | 0.000138 |
S | 884 | S884F | tCt | tTt | 22 | 22 | AY.43 | 0.000097 |
S | 884 | S884F | tCt | tTt | 22 | 22 | AY.44 | 0.000134 |
S | 884 | S884F | tCt | tTt | 22 | 22 | B.1.617.2 | 0.000083 |
S | 884 | S884F | tCt | tTt | 20 | 20 | B.1.429 | 0.000471 |
S | 884 | S884F | tCt | tTt | 20 | 20 | D.2 | 0.001501 |
S | 884 | S884F | tCt | tTt | 17 | 17 | B.1.1 | 0.000308 |
S | 884 | S884F | tCt | tTt | 14 | 14 | AY.103 | 0.000087 |
S | 884 | S884F | tCt | tTt | 11 | 11 | AY.120 | 0.000409 |
S | 884 | S884F | tCt | tTt | 9 | 9 | AY.3 | 0.00009 |
S | 884 | S884F | tCt | tTt | 7 | 7 | AY.39 | 0.000173 |
S | 884 | S884F | tCt | tTt | 7 | 7 | B | 0.000895 |
S | 884 | S884F | tCt | tTt | 7 | 7 | B.1.177.21 | 0.000535 |
S | 884 | S884F | tCt | tTt | 6 | 6 | AY.102 | 0.000159 |
S | 884 | S884F | tCt | tTt | 6 | 6 | AY.29 | 0.000095 |
S | 884 | S884F | tCt | tTt | 6 | 6 | AY.5 | 0.000124 |
S | 884 | S884F | tCt | tTt | 6 | 6 | B.1.160 | 0.000187 |
S | 884 | S884F | tCt | tTt | 5 | 5 | AY.34 | 0.000485 |
S | 884 | S884F | tCt | tTt | 5 | 5 | AY.39.1 | 0.000198 |
S | 884 | S884F | tCt | tTt | 5 | 5 | B.1.1.214 | 0.000277 |
S | 884 | S884F | tCt | tTt | 5 | 5 | B.1.1.33 | 0.002104 |
S | 884 | S884F | tCt | tTt | 5 | 5 | B.1.1.519 | 0.000199 |
S | 884 | S884F | tCt | tTt | 5 | 5 | B.1.427 | 0.000252 |
S | 884 | S884F | tCt | tTt | 4 | 4 | AY.42 | 0.000161 |
S | 884 | S884F | tCt | tTt | 4 | 4 | AY.47 | 0.000124 |
S | 884 | S884F | tCt | tTt | 4 | 4 | AY.98 | 0.000316 |
S | 884 | S884F | tCt | tTt | 4 | 4 | AZ.5 | 0.014035 |
S | 884 | S884F | tCt | tTt | 4 | 4 | B.1.258 | 0.000266 |
S | 884 | S884F | tCt | tTt | 4 | 4 | B.1.351 | 0.000119 |
S | 884 | S884F | tCt | tTt | 4 | 4 | P.1.14 | 0.000191 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.110 | 0.000338 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.23 | 0.000209 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.3.1 | 0.000256 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.33 | 0.0002 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.4.2 | 0.000065 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.7.1 | 0.000338 |
S | 884 | S884F | tCt | tTt | 3 | 3 | AY.9.2 | 0.00011 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.1.222 | 0.000612 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.1.50 | 0.002037 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.177.7 | 0.000495 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.311 | 0.000824 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.351.5 | 0.001799 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.416.1 | 0.004687 |
S | 884 | S884F | tCt | tTt | 3 | 3 | B.1.438.1 | 0.000322 |
S | 884 | S884F | tCt | tTt | 3 | 3 | P.1 | 0.000047 |
S | 884 | S884F | tCt | tTt | 3 | 3 | Q.1 | 0.000379 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AD.2 | 0.000438 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.100 | 0.000092 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.113 | 0.000285 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.116 | 0.000574 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.20 | 0.000078 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.26 | 0.000057 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.27 | 0.000129 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.36 | 0.000296 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.46 | 0.000208 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.46.6 | 0.000144 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.9 | 0.000135 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.90 | 0.001369 |
S | 884 | S884F | tCt | tTt | 2 | 2 | AY.98.1 | 0.000097 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.1.176 | 0.000879 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.1.269 | 0.002706 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.1.277 | 0.001517 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.1.37 | 0.000386 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.1.434 | 0.000697 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.1.70 | 0.000682 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.177.12 | 0.000303 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.177.57 | 0.000562 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.177.86 | 0.000367 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.206 | 0.001631 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.234 | 0.000264 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.243 | 0.000139 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.36 | 0.000292 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.448 | 0.005249 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.517.1 | 0.010526 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.617.1 | 0.000258 |
S | 884 | S884F | tCt | tTt | 2 | 2 | B.1.637 | 0.000146 |
S | 884 | S884F | tCt | tTt | 2 | 2 | P.1.10 | 0.000539 |
S | 884 | S884F | tCt | tTt | 2 | 2 | P.1.16 | 0.000748 |
S | 884 | S884F | tCt | tTt | 2 | 2 | Q.3 | 0.00029 |
S | 884 | S884F | tCt | tTt | 1 | 1 | A.1 | 0.000282 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AE.8 | 0.000489 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AL.1 | 0.012987 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.107 | 0.000466 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.11 | 0.001339 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.111 | 0.000183 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.119 | 0.000035 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.120.2 | 0.001285 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.120.2.1 | 0.000498 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.121 | 0.000135 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.2 | 0.000356 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.22 | 0.002092 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.32 | 0.000532 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.4.4 | 0.000409 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.46.5 | 0.000198 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.48 | 0.000465 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.5.3 | 0.000337 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.6 | 0.000041 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.61 | 0.000105 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.73 | 0.000665 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.74 | 0.000116 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.77 | 0.001127 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.78 | 0.001541 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.85 | 0.000427 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.92 | 0.000287 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.93 | 0.000273 |
S | 884 | S884F | tCt | tTt | 1 | 1 | AY.97 | 0.001701 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.122 | 0.045455 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.186 | 0.003436 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.198 | 0.001468 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.216 | 0.00089 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.25 | 0.000569 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.280 | 0.003086 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.284 | 0.000107 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.291 | 0.000742 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.306 | 0.000438 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.316 | 0.000925 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.317 | 0.000412 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.318 | 0.000302 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.322 | 0.008772 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.368 | 0.003086 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.369 | 0.000446 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.39 | 0.00051 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.47 | 0.005348 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.51 | 0.001718 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.1.513 | 0.012346 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.160.22 | 0.006757 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.160.32 | 0.004292 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.15 | 0.000631 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.4 | 0.000211 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.41 | 0.0025 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.45 | 0.000381 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.48 | 0.003125 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.60 | 0.000218 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.65 | 0.000665 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.74 | 0.015152 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.75 | 0.001041 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.77 | 0.000726 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.8 | 0.000752 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.177.80 | 0.001912 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.221 | 0.000071 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.23 | 0.006061 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.240 | 0.000216 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.258.17 | 0.000104 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.258.7 | 0.001912 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.282 | 0.014925 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.338 | 0.008621 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.351.1 | 0.038462 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.36.17 | 0.000494 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.36.18 | 0.00042 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.36.31 | 0.001751 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.389 | 0.001002 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.397 | 0.004854 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.400 | 0.000429 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.413 | 0.004255 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.422 | 0.000812 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.426 | 0.001009 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.428 | 0.00102 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.436 | 0.001029 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.469 | 0.00361 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.471 | 0.002732 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.497 | 0.000315 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.503 | 0.002488 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.524 | 0.001406 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.525 | 0.000113 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.526 | 0.000024 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.532 | 0.006211 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.538 | 0.008065 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.564.1 | 0.001577 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.575 | 0.000303 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.596 | 0.000087 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.621 | 0.000089 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.1.628 | 0.000352 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.4.5 | 0.011905 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.6 | 0.00091 |
S | 884 | S884F | tCt | tTt | 1 | 1 | B.6.3 | 0.026316 |
S | 884 | S884F | tCt | tTt | 1 | 1 | C.3 | 0.007634 |
S | 884 | S884F | tCt | tTt | 1 | 1 | C.37 | 0.000116 |
S | 884 | S884F | tCt | tTt | 1 | 1 | Q.8 | 0.000165 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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