CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 871 | A871S | nonsyn | Gct | Tct | 1734 | 1734 | 1 | 24173-24175 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 871 | A871S | Gct | Tct | 1734 | 1734 | All | 0.000332 |
S | 871 | A871S | Gct | Tct | 480 | 480 | AY.4 | 0.000747 |
S | 871 | A871S | Gct | Tct | 321 | 321 | B.1.1.7 | 0.000287 |
S | 871 | A871S | Gct | Tct | 88 | 88 | B.1.617.2 | 0.000331 |
S | 871 | A871S | Gct | Tct | 80 | 80 | AY.103 | 0.000497 |
S | 871 | A871S | Gct | Tct | 57 | 57 | AY.29 | 0.000899 |
S | 871 | A871S | Gct | Tct | 53 | 53 | AY.43 | 0.000235 |
S | 871 | A871S | Gct | Tct | 37 | 37 | B.1.177.7 | 0.0061 |
S | 871 | A871S | Gct | Tct | 32 | 32 | AY.27 | 0.002071 |
S | 871 | A871S | Gct | Tct | 28 | 28 | AY.25 | 0.000168 |
S | 871 | A871S | Gct | Tct | 26 | 26 | AY.26 | 0.000736 |
S | 871 | A871S | Gct | Tct | 26 | 26 | AY.3.1 | 0.002217 |
S | 871 | A871S | Gct | Tct | 25 | 25 | B.1 | 0.000229 |
S | 871 | A871S | Gct | Tct | 23 | 23 | AY.44 | 0.00014 |
S | 871 | A871S | Gct | Tct | 19 | 19 | B.1.177 | 0.00025 |
S | 871 | A871S | Gct | Tct | 19 | 19 | B.1.2 | 0.000167 |
S | 871 | A871S | Gct | Tct | 18 | 18 | AY.3 | 0.000179 |
S | 871 | A871S | Gct | Tct | 17 | 17 | P.1 | 0.000268 |
S | 871 | A871S | Gct | Tct | 16 | 16 | AY.84 | 0.006999 |
S | 871 | A871S | Gct | Tct | 14 | 14 | AY.102 | 0.000371 |
S | 871 | A871S | Gct | Tct | 14 | 14 | B.1.526 | 0.000329 |
S | 871 | A871S | Gct | Tct | 13 | 13 | B.1.177.87 | 0.009461 |
S | 871 | A871S | Gct | Tct | 11 | 11 | AY.5 | 0.000227 |
S | 871 | A871S | Gct | Tct | 11 | 11 | C.36.3 | 0.006239 |
S | 871 | A871S | Gct | Tct | 10 | 10 | AY.20 | 0.000389 |
S | 871 | A871S | Gct | Tct | 10 | 10 | AY.39 | 0.000247 |
S | 871 | A871S | Gct | Tct | 10 | 10 | B.1.1 | 0.000181 |
S | 871 | A871S | Gct | Tct | 10 | 10 | B.1.1.214 | 0.000555 |
S | 871 | A871S | Gct | Tct | 10 | 10 | P.1.17 | 0.001618 |
S | 871 | A871S | Gct | Tct | 8 | 8 | AY.116.1 | 0.002491 |
S | 871 | A871S | Gct | Tct | 7 | 7 | B.1.160 | 0.000218 |
S | 871 | A871S | Gct | Tct | 7 | 7 | B.1.631 | 0.023569 |
S | 871 | A871S | Gct | Tct | 7 | 7 | P.1.1 | 0.002224 |
S | 871 | A871S | Gct | Tct | 6 | 6 | AY.42 | 0.000241 |
S | 871 | A871S | Gct | Tct | 6 | 6 | AY.47 | 0.000187 |
S | 871 | A871S | Gct | Tct | 6 | 6 | B.1.369 | 0.001711 |
S | 871 | A871S | Gct | Tct | 6 | 6 | B.1.596 | 0.000523 |
S | 871 | A871S | Gct | Tct | 5 | 5 | AY.23 | 0.000349 |
S | 871 | A871S | Gct | Tct | 5 | 5 | AY.54 | 0.000477 |
S | 871 | A871S | Gct | Tct | 5 | 5 | B.1.351 | 0.000149 |
S | 871 | A871S | Gct | Tct | 5 | 5 | B.1.36 | 0.00073 |
S | 871 | A871S | Gct | Tct | 5 | 5 | P.1.14 | 0.000239 |
S | 871 | A871S | Gct | Tct | 4 | 4 | AY.30 | 0.001583 |
S | 871 | A871S | Gct | Tct | 4 | 4 | AY.61 | 0.000419 |
S | 871 | A871S | Gct | Tct | 4 | 4 | B.1.177.24 | 0.005181 |
S | 871 | A871S | Gct | Tct | 4 | 4 | B.1.177.54 | 0.002426 |
S | 871 | A871S | Gct | Tct | 4 | 4 | B.1.637 | 0.000292 |
S | 871 | A871S | Gct | Tct | 3 | 3 | A.2.5 | 0.001497 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.100 | 0.000138 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.106 | 0.001005 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.119 | 0.000106 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.12 | 0.000948 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.33 | 0.0002 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.34 | 0.000291 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.39.1 | 0.000119 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.4.2 | 0.000065 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.62 | 0.001307 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.7.1 | 0.000338 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.9.2 | 0.00011 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AY.98.1 | 0.000145 |
S | 871 | A871S | Gct | Tct | 3 | 3 | AZ.3 | 0.004559 |
S | 871 | A871S | Gct | Tct | 3 | 3 | B.1.160.7 | 0.006237 |
S | 871 | A871S | Gct | Tct | 3 | 3 | B.1.429 | 0.000071 |
S | 871 | A871S | Gct | Tct | 3 | 3 | B.1.621 | 0.000266 |
S | 871 | A871S | Gct | Tct | 3 | 3 | B.1.625 | 0.007059 |
S | 871 | A871S | Gct | Tct | 3 | 3 | Q.3 | 0.000435 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.116 | 0.000574 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.120 | 0.000074 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.121 | 0.000271 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.13 | 0.000322 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.29.1 | 0.000441 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.4.5 | 0.000215 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.46.2 | 0.001271 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.52 | 0.001629 |
S | 871 | A871S | Gct | Tct | 2 | 2 | AY.9 | 0.000135 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.1.222 | 0.000408 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.1.244 | 0.030769 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.1.28 | 0.000622 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.1.448 | 0.004065 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.177.17 | 0.001642 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.36.29 | 0.001035 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.36.38 | 0.003284 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.466.2 | 0.000782 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.525 | 0.000226 |
S | 871 | A871S | Gct | Tct | 2 | 2 | B.1.617.1 | 0.000258 |
S | 871 | A871S | Gct | Tct | 2 | 2 | D.2 | 0.00015 |
S | 871 | A871S | Gct | Tct | 1 | 1 | A.2.4 | 0.003367 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AD.2 | 0.000219 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.107 | 0.000466 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.111 | 0.000183 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.117 | 0.000085 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.14 | 0.000088 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.16.1 | 0.00047 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.2 | 0.000356 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.23.1 | 0.000417 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.37 | 0.000316 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.41 | 0.000294 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.46 | 0.000104 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.46.6 | 0.000072 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.57 | 0.000656 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.6 | 0.000041 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.69 | 0.000187 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.7 | 0.000196 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.74 | 0.000116 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.75.1 | 0.00018 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.9.1 | 0.000084 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.95 | 0.000761 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AY.99.1 | 0.001553 |
S | 871 | A871S | Gct | Tct | 1 | 1 | AZ.2 | 0.000821 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B | 0.000128 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.171 | 0.003676 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.174 | 0.003378 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.289 | 0.002083 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.294 | 0.001266 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.298 | 0.000862 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.326 | 0.001761 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.33 | 0.000421 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.331 | 0.011628 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.348 | 0.000796 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.358 | 0.034483 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.37 | 0.000193 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.432 | 0.001266 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.50 | 0.000679 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.507 | 0.008696 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.519 | 0.00004 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.1.70 | 0.000341 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.142 | 0.002899 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.177.41 | 0.0025 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.177.43 | 0.001477 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.177.48 | 0.003125 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.177.8 | 0.000752 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.177.86 | 0.000183 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.206 | 0.000816 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.221 | 0.000071 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.232 | 0.000537 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.234 | 0.000132 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.311 | 0.000275 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.320 | 0.001245 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.351.2 | 0.000303 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.565 | 0.00081 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.575 | 0.000303 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.595.2 | 0.04 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.1.619.1 | 0.000641 |
S | 871 | A871S | Gct | Tct | 1 | 1 | B.49 | 0.05 |
S | 871 | A871S | Gct | Tct | 1 | 1 | P.1.15 | 0.000232 |
S | 871 | A871S | Gct | Tct | 1 | 1 | P.1.8 | 0.004785 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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