CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 846 | A846V | nonsyn | gCt | gTt | 2937 | 2934 | 0.998979 | 24098-24100 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 846 | A846V | gCt | gTt | 2934 | 2937 | All | 0.000561 |
S | 846 | A846V | gCt | gTt | 667 | 667 | AY.3.1 | 0.056868 |
S | 846 | A846V | gCt | gTt | 408 | 408 | B.1.1.7 | 0.000365 |
S | 846 | A846V | gCt | gTt | 198 | 198 | AY.4 | 0.000308 |
S | 846 | A846V | gCt | gTt | 171 | 171 | AY.25 | 0.001029 |
S | 846 | A846V | gCt | gTt | 106 | 106 | B.1.429 | 0.002494 |
S | 846 | A846V | gCt | gTt | 98 | 98 | B.1.617.2 | 0.000369 |
S | 846 | A846V | gCt | gTt | 94 | 94 | B.1.1.75 | 1 |
S | 846 | A846V | gCt | gTt | 81 | 81 | AY.43 | 0.000359 |
S | 846 | A846V | gCt | gTt | 77 | 80 | B.1.2 | 0.000678 |
S | 846 | A846V | gCt | gTt | 73 | 73 | AY.103 | 0.000453 |
S | 846 | A846V | gCt | gTt | 60 | 60 | B.1.221 | 0.004262 |
S | 846 | A846V | gCt | gTt | 57 | 57 | B.1.1.459 | 0.876923 |
S | 846 | A846V | gCt | gTt | 54 | 54 | B.1.221.3 | 0.045 |
S | 846 | A846V | gCt | gTt | 52 | 52 | AY.44 | 0.000317 |
S | 846 | A846V | gCt | gTt | 44 | 44 | B.1.177 | 0.000579 |
S | 846 | A846V | gCt | gTt | 42 | 42 | B.1.1 | 0.000762 |
S | 846 | A846V | gCt | gTt | 31 | 31 | AY.3 | 0.000308 |
S | 846 | A846V | gCt | gTt | 31 | 31 | B.1.1.519 | 0.001231 |
S | 846 | A846V | gCt | gTt | 31 | 31 | B.1.177.2 | 0.140909 |
S | 846 | A846V | gCt | gTt | 27 | 27 | AY.46.6 | 0.00195 |
S | 846 | A846V | gCt | gTt | 27 | 27 | B.1.160 | 0.000842 |
S | 846 | A846V | gCt | gTt | 24 | 24 | B.1 | 0.00022 |
S | 846 | A846V | gCt | gTt | 18 | 18 | B.1.258 | 0.001198 |
S | 846 | A846V | gCt | gTt | 14 | 14 | P.1 | 0.000221 |
S | 846 | A846V | gCt | gTt | 13 | 13 | AY.120 | 0.000483 |
S | 846 | A846V | gCt | gTt | 11 | 11 | AY.117 | 0.00093 |
S | 846 | A846V | gCt | gTt | 11 | 11 | AY.20 | 0.000428 |
S | 846 | A846V | gCt | gTt | 11 | 11 | AY.61 | 0.001153 |
S | 846 | A846V | gCt | gTt | 10 | 10 | B.1.1.214 | 0.000555 |
S | 846 | A846V | gCt | gTt | 10 | 10 | B.1.1.294 | 0.012658 |
S | 846 | A846V | gCt | gTt | 10 | 10 | B.1.637 | 0.000731 |
S | 846 | A846V | gCt | gTt | 8 | 8 | AY.5 | 0.000165 |
S | 846 | A846V | gCt | gTt | 8 | 8 | B.1.177.32 | 0.010796 |
S | 846 | A846V | gCt | gTt | 8 | 8 | B.1.351 | 0.000238 |
S | 846 | A846V | gCt | gTt | 7 | 7 | AY.100 | 0.000322 |
S | 846 | A846V | gCt | gTt | 7 | 7 | AY.39 | 0.000173 |
S | 846 | A846V | gCt | gTt | 7 | 7 | AY.4.2 | 0.000152 |
S | 846 | A846V | gCt | gTt | 7 | 7 | AY.6 | 0.000288 |
S | 846 | A846V | gCt | gTt | 6 | 6 | AY.102 | 0.000159 |
S | 846 | A846V | gCt | gTt | 6 | 6 | AY.29 | 0.000095 |
S | 846 | A846V | gCt | gTt | 6 | 6 | AY.46 | 0.000624 |
S | 846 | A846V | gCt | gTt | 6 | 6 | B.1.243 | 0.000418 |
S | 846 | A846V | gCt | gTt | 6 | 6 | B.1.595 | 0.001566 |
S | 846 | A846V | gCt | gTt | 5 | 5 | AY.113 | 0.000712 |
S | 846 | A846V | gCt | gTt | 5 | 5 | AY.121 | 0.000677 |
S | 846 | A846V | gCt | gTt | 5 | 5 | AY.34.1 | 0.00255 |
S | 846 | A846V | gCt | gTt | 5 | 5 | AY.47 | 0.000156 |
S | 846 | A846V | gCt | gTt | 5 | 5 | AY.9 | 0.000338 |
S | 846 | A846V | gCt | gTt | 5 | 5 | B.1.1.318 | 0.001509 |
S | 846 | A846V | gCt | gTt | 5 | 5 | B.1.369 | 0.001426 |
S | 846 | A846V | gCt | gTt | 5 | 5 | B.1.526 | 0.000118 |
S | 846 | A846V | gCt | gTt | 5 | 5 | B.1.596 | 0.000436 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.116 | 0.001147 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.26 | 0.000113 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.33 | 0.000267 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.34 | 0.000388 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.42 | 0.000161 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.9.2 | 0.000147 |
S | 846 | A846V | gCt | gTt | 4 | 4 | AY.96 | 0.008299 |
S | 846 | A846V | gCt | gTt | 4 | 4 | B.1.1.161 | 0.014134 |
S | 846 | A846V | gCt | gTt | 4 | 4 | B.1.1.317 | 0.001647 |
S | 846 | A846V | gCt | gTt | 4 | 4 | B.1.177.45 | 0.001525 |
S | 846 | A846V | gCt | gTt | 4 | 4 | B.1.389 | 0.004008 |
S | 846 | A846V | gCt | gTt | 4 | 4 | R.1 | 0.00036 |
S | 846 | A846V | gCt | gTt | 3 | 3 | A.2.5 | 0.001497 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.23 | 0.000209 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.39.1 | 0.000119 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.45 | 0.000365 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.5.4 | 0.00083 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.75 | 0.000168 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.9.1 | 0.000251 |
S | 846 | A846V | gCt | gTt | 3 | 3 | AY.92 | 0.000862 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B | 0.000383 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.1.10 | 0.003344 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.162 | 0.015075 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.177.81 | 0.000568 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.232 | 0.001612 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.234 | 0.000396 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.311 | 0.000824 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.36.17 | 0.001482 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.575 | 0.00091 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.612 | 0.007958 |
S | 846 | A846V | gCt | gTt | 3 | 3 | B.1.618 | 0.012097 |
S | 846 | A846V | gCt | gTt | 3 | 3 | W.1 | 0.026087 |
S | 846 | A846V | gCt | gTt | 2 | 2 | A.28 | 0.005291 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.109 | 0.001479 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.111 | 0.000366 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.118 | 0.000125 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.119 | 0.000071 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.14 | 0.000176 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.4.5 | 0.000215 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.46.2 | 0.001271 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.59 | 0.001059 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.69 | 0.000373 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.74 | 0.000231 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.84 | 0.000875 |
S | 846 | A846V | gCt | gTt | 2 | 2 | AY.98 | 0.000158 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.1.284 | 0.000215 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.1.434 | 0.000697 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.177.12 | 0.000303 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.177.57 | 0.000562 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.177.62 | 0.002384 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.177.65 | 0.001331 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.177.7 | 0.00033 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.177.86 | 0.000367 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.224 | 0.05 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.236 | 0.004107 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.258.17 | 0.000208 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.36.18 | 0.00084 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.427 | 0.000101 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.433 | 0.00639 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.466.2 | 0.000782 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.561 | 0.000794 |
S | 846 | A846V | gCt | gTt | 2 | 2 | B.1.617.1 | 0.000258 |
S | 846 | A846V | gCt | gTt | 2 | 2 | C.37 | 0.000232 |
S | 846 | A846V | gCt | gTt | 2 | 2 | D.2 | 0.00015 |
S | 846 | A846V | gCt | gTt | 2 | 2 | N.5 | 0.003534 |
S | 846 | A846V | gCt | gTt | 2 | 2 | Q.1 | 0.000253 |
S | 846 | A846V | gCt | gTt | 1 | 1 | 0.055556 | |
S | 846 | A846V | gCt | gTt | 1 | 1 | A | 0.000387 |
S | 846 | A846V | gCt | gTt | 1 | 1 | A.2.5.1 | 0.004808 |
S | 846 | A846V | gCt | gTt | 1 | 1 | A.21 | 0.00277 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AE.8 | 0.000489 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AM.2 | 0.111111 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AM.4 | 0.003571 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.120.1 | 0.000321 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.120.2 | 0.001285 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.24 | 0.000431 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.27 | 0.000065 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.32 | 0.000532 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.54 | 0.000095 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.55 | 0.000917 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.58 | 0.000907 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.60 | 0.000938 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.68 | 0.000274 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.71 | 0.000475 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.79 | 0.001211 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.87 | 0.000833 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.88 | 0.000884 |
S | 846 | A846V | gCt | gTt | 1 | 1 | AY.98.1 | 0.000048 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.117 | 0.009709 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.166 | 0.033333 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.170 | 0.001247 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.25 | 0.000569 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.277 | 0.000759 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.306 | 0.000438 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.326 | 0.001761 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.349 | 0.010309 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.368 | 0.003086 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.37 | 0.000193 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.391 | 0.008547 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.406 | 0.006494 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.416 | 0.000905 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.1.528 | 0.004808 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.160.16 | 0.000929 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.177.10 | 0.000878 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.177.52 | 0.001757 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.177.53 | 0.002392 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.177.56 | 0.000668 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.3 | 0.002618 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.324 | 0.001605 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.329 | 0.000608 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.36 | 0.000146 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.36.26 | 0.002857 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.36.29 | 0.000517 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.377 | 0.004566 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.385 | 0.010638 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.400 | 0.000429 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.428 | 0.00102 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.438.1 | 0.000107 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.469 | 0.00361 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.525 | 0.000113 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.538 | 0.008065 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.551 | 0.00129 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.564 | 0.000426 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.621 | 0.000089 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.1.93 | 0.000934 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.12 | 0.00641 |
S | 846 | A846V | gCt | gTt | 1 | 1 | B.55 | 0.00295 |
S | 846 | A846V | gCt | gTt | 1 | 1 | C.36 | 0.000911 |
S | 846 | A846V | gCt | gTt | 1 | 1 | C.36.3 | 0.000567 |
S | 846 | A846V | gCt | gTt | 1 | 1 | D.5 | 0.004975 |
S | 846 | A846V | gCt | gTt | 1 | 1 | P.1.14 | 0.000048 |
S | 846 | A846V | gCt | gTt | 1 | 1 | P.1.2 | 0.001156 |
S | 846 | A846V | gCt | gTt | 1 | 1 | P.2 | 0.000187 |
S | 846 | A846V | gCt | gTt | 1 | 1 | P.6 | 0.003145 |
S | 846 | A846V | gCt | gTt | 1 | 1 | Q.3 | 0.000145 |
S | 846 | A846V | gCt | gTt | 1 | 1 | Q.4 | 0.000455 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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