CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 846 | A846S | nonsyn | Gct | Tct | 1829 | 1827 | 0.998906 | 24098-24100 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 846 | A846S | Gct | Tct | 1827 | 1829 | All | 0.000349 |
S | 846 | A846S | Gct | Tct | 277 | 277 | AY.4 | 0.000431 |
S | 846 | A846S | Gct | Tct | 214 | 214 | B.1.1.7 | 0.000192 |
S | 846 | A846S | Gct | Tct | 177 | 177 | AY.25 | 0.001065 |
S | 846 | A846S | Gct | Tct | 153 | 153 | AY.43 | 0.000678 |
S | 846 | A846S | Gct | Tct | 119 | 119 | AY.4.2 | 0.002581 |
S | 846 | A846S | Gct | Tct | 97 | 97 | B.1.617.2 | 0.000365 |
S | 846 | A846S | Gct | Tct | 96 | 96 | B.1.177.17 | 0.078818 |
S | 846 | A846S | Gct | Tct | 50 | 50 | B.28 | 0.163934 |
S | 846 | A846S | Gct | Tct | 44 | 44 | AY.42 | 0.00177 |
S | 846 | A846S | Gct | Tct | 39 | 39 | AY.103 | 0.000242 |
S | 846 | A846S | Gct | Tct | 35 | 35 | B.1.2 | 0.000308 |
S | 846 | A846S | Gct | Tct | 32 | 32 | P.2 | 0.005972 |
S | 846 | A846S | Gct | Tct | 31 | 31 | B.1 | 0.000284 |
S | 846 | A846S | Gct | Tct | 24 | 24 | AY.120 | 0.000892 |
S | 846 | A846S | Gct | Tct | 23 | 23 | B.1.351 | 0.000684 |
S | 846 | A846S | Gct | Tct | 22 | 22 | AY.46.6 | 0.001589 |
S | 846 | A846S | Gct | Tct | 21 | 21 | AY.39 | 0.000519 |
S | 846 | A846S | Gct | Tct | 19 | 19 | AY.117 | 0.001606 |
S | 846 | A846S | Gct | Tct | 18 | 18 | AY.44 | 0.00011 |
S | 846 | A846S | Gct | Tct | 16 | 16 | AY.29 | 0.000252 |
S | 846 | A846S | Gct | Tct | 13 | 13 | AY.102 | 0.000345 |
S | 846 | A846S | Gct | Tct | 13 | 13 | AY.3 | 0.000129 |
S | 846 | A846S | Gct | Tct | 13 | 13 | P.1 | 0.000205 |
S | 846 | A846S | Gct | Tct | 12 | 12 | B.1.1 | 0.000218 |
S | 846 | A846S | Gct | Tct | 12 | 12 | B.1.177.87 | 0.008734 |
S | 846 | A846S | Gct | Tct | 11 | 11 | AY.46.5 | 0.002183 |
S | 846 | A846S | Gct | Tct | 11 | 11 | B.1.177 | 0.000145 |
S | 846 | A846S | Gct | Tct | 9 | 9 | AY.120.1 | 0.002889 |
S | 846 | A846S | Gct | Tct | 9 | 9 | AY.4.5 | 0.000967 |
S | 846 | A846S | Gct | Tct | 9 | 9 | AY.47 | 0.00028 |
S | 846 | A846S | Gct | Tct | 8 | 8 | AY.54 | 0.000763 |
S | 846 | A846S | Gct | Tct | 8 | 8 | B.1.526 | 0.000188 |
S | 846 | A846S | Gct | Tct | 7 | 7 | AY.121 | 0.000947 |
S | 846 | A846S | Gct | Tct | 7 | 7 | AY.5 | 0.000145 |
S | 846 | A846S | Gct | Tct | 7 | 7 | AY.61 | 0.000733 |
S | 846 | A846S | Gct | Tct | 7 | 7 | AY.98.1 | 0.000339 |
S | 846 | A846S | Gct | Tct | 6 | 6 | B.1.1.70 | 0.002046 |
S | 846 | A846S | Gct | Tct | 5 | 5 | AY.14 | 0.00044 |
S | 846 | A846S | Gct | Tct | 5 | 5 | AY.34 | 0.000485 |
S | 846 | A846S | Gct | Tct | 5 | 5 | B.1.1.28 | 0.001556 |
S | 846 | A846S | Gct | Tct | 5 | 5 | B.1.429 | 0.000118 |
S | 846 | A846S | Gct | Tct | 2 | 4 | 0.111111 | |
S | 846 | A846S | Gct | Tct | 4 | 4 | AD.2 | 0.000876 |
S | 846 | A846S | Gct | Tct | 4 | 4 | B.1.1.519 | 0.000159 |
S | 846 | A846S | Gct | Tct | 4 | 4 | B.1.223 | 0.011111 |
S | 846 | A846S | Gct | Tct | 4 | 4 | P.1.7 | 0.001277 |
S | 846 | A846S | Gct | Tct | 3 | 3 | AY.39.1 | 0.000119 |
S | 846 | A846S | Gct | Tct | 3 | 3 | AY.53 | 0.000863 |
S | 846 | A846S | Gct | Tct | 3 | 3 | AY.99.2 | 0.000276 |
S | 846 | A846S | Gct | Tct | 3 | 3 | B.1.221 | 0.000213 |
S | 846 | A846S | Gct | Tct | 3 | 3 | B.1.36 | 0.000438 |
S | 846 | A846S | Gct | Tct | 2 | 2 | A.23.1 | 0.001408 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.111 | 0.000366 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.113 | 0.000285 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.119 | 0.000071 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.23 | 0.000139 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.32 | 0.001065 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.35 | 0.000466 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.36 | 0.000296 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.38 | 0.000999 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.4.4 | 0.000818 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.46.4 | 0.000329 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.5.4 | 0.000553 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.60 | 0.001876 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.7.1 | 0.000225 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.9 | 0.000135 |
S | 846 | A846S | Gct | Tct | 2 | 2 | AY.9.2 | 0.000073 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.1.214 | 0.000111 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.1.306 | 0.000877 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.170 | 0.008621 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.177.81 | 0.000379 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.221.3 | 0.001667 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.240 | 0.000431 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.311 | 0.000549 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.36.29 | 0.001035 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.427 | 0.000101 |
S | 846 | A846S | Gct | Tct | 2 | 2 | B.1.637 | 0.000146 |
S | 846 | A846S | Gct | Tct | 2 | 2 | Q.1 | 0.000253 |
S | 846 | A846S | Gct | Tct | 2 | 2 | Q.4 | 0.00091 |
S | 846 | A846S | Gct | Tct | 1 | 1 | A | 0.000387 |
S | 846 | A846S | Gct | Tct | 1 | 1 | A.4 | 0.012821 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.106 | 0.000335 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.114 | 0.000231 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.118 | 0.000063 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.16 | 0.00038 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.20 | 0.000039 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.33 | 0.000067 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.45 | 0.000122 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.46 | 0.000104 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.5.3 | 0.000337 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.55 | 0.000917 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.70 | 0.000209 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.75 | 0.000056 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.75.1 | 0.00018 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.9.1 | 0.000084 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.91 | 0.00073 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.93 | 0.000273 |
S | 846 | A846S | Gct | Tct | 1 | 1 | AY.98 | 0.000079 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B | 0.000128 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.1.189 | 0.001513 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.1.318 | 0.000302 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.1.374 | 0.002375 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.160 | 0.000031 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.177.32 | 0.00135 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.177.60 | 0.000218 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.177.7 | 0.000165 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.234 | 0.000132 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.258.11 | 0.000396 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.258.17 | 0.000104 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.36.18 | 0.00042 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.36.19 | 0.009259 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.362 | 0.001541 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.369 | 0.000285 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.396 | 0.000706 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.404 | 0.001302 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.504 | 0.03125 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.517 | 0.000427 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.565 | 0.00081 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.575 | 0.000303 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.596 | 0.000087 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.620 | 0.000946 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.621 | 0.000089 |
S | 846 | A846S | Gct | Tct | 1 | 1 | B.1.9.4 | 0.006135 |
S | 846 | A846S | Gct | Tct | 1 | 1 | C.37 | 0.000116 |
S | 846 | A846S | Gct | Tct | 1 | 1 | P.1.1 | 0.000318 |
S | 846 | A846S | Gct | Tct | 1 | 1 | P.1.17 | 0.000162 |
S | 846 | A846S | Gct | Tct | 1 | 1 | P.7 | 0.004367 |
S | 846 | A846S | Gct | Tct | 1 | 1 | Q.3 | 0.000145 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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