CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 751

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S751N751NsynaaTaaC747747123813-23815
S751N751DnonsynAatGat295295123813-23815
S751N751KnonsynaaTaaG1871840.98395723813-23815
S751N751KnonsynaaTaaA18730.016042823813-23815
S751N751TnonsynaAtaCt122122123813-23815
S751N751SnonsynaAtaGt116116123813-23815
S751N751YnonsynAatTat101101123813-23815
S751N751InonsynaAtaTt9898123813-23815
S751N751deldelAAT---5151123813-23815
S751N751del1delaaTaa-980.88888923813-23815
S751N751del1delAat-at910.11111123813-23815
S751N751HnonsynAatCat88123813-23815
S751N751del2delaATa--22123813-23815
S751N751AnonsynAAtGCt11123813-23815
S751N751EnonsynAaTGaA11123813-23815

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S751N751NaaTaaC747747All0.000143
S751N751DAatGat295295All0.000056
S751N751KaaTaaG184187All0.000035
S751N751KaaTaaA3187All0.000001
S751N751NaaTaaC182182B.1.3510.00541
S751N751DAatGat133133R.10.011971
S751N751TaAtaCt122122All0.000023
S751N751SaAtaGt116116All0.000022
S751N751NaaTaaC103103B.1.1.70.000092
S751N751YAatTat101101All0.000019
S751N751IaAtaTt9898All0.000019
S751N751KaaTaaG8686B.1.1.70.000077
S751N751IaAtaTt6868AY.40.000106
S751N751KaaTaaG6868B.1.243.20.985507
S751N751delAAT---5151All0.00001
S751N751DAatGat4343AY.470.001338
S751N751NaaTaaC4242AY.40.000065
S751N751TaAtaCt4141AY.30.000408
S751N751TaAtaCt4141AY.39.10.001624
S751N751NaaTaaC3939B.1.4290.000918
S751N751DAatGat3737AY.340.003588
S751N751NaaTaaC3535AY.1030.000217
S751N751NaaTaaC3535AY.50.000723
S751N751NaaTaaC3434B.1.4270.001717
S751N751NaaTaaC2727B.1.1770.000356
S751N751SaAtaGt2525AY.40.000039
S751N751YAatTat2424B.1.1.70.000021
S751N751SaAtaGt2323AY.50.000475
S751N751YAatTat2323B.1.1.2980.019828
S751N751NaaTaaC2222AP.10.033033
S751N751DAatGat1919B.1.1.70.000017
S751N751NaaTaaC1818B.1.20.000158
S751N751NaaTaaC1616B.1.617.20.00006
S751N751NaaTaaC1515B.10.000137
S751N751DAatGat1414AY.440.000085
S751N751DAatGat1313AY.250.000078
S751N751SaAtaGt1313AY.3.10.001108
S751N751SaAtaGt1212B.1.1.70.000011
S751N751NaaTaaC1212B.1.2430.000835
S751N751YAatTat1212P.1.140.000574
S751N751NaaTaaC1111AY.730.007319
S751N751NaaTaaC1111B.1.5750.003337
S751N751del1aaTaa-89All0.000002
S751N751del1Aat-at19All0
S751N751NaaTaaC99B.1.360.001313
S751N751TaAtaCt99P.1.70.002874
S751N751HAatCat88All0.000002
S751N751NaaTaaC88AY.250.000048
S751N751IaAtaTt88AY.430.000035
S751N751KaaTaaG88B.1.3060.045714
S751N751NaaTaaC88B.1.36.10.009122
S751N751IaAtaTt77B.1.1.3170.002882
S751N751NaaTaaC66AY.30.00006
S751N751YAatTat66AY.40.000009
S751N751TaAtaCt66B.1.1.70.000005
S751N751NaaTaaC66B.1.3980.017857
S751N751delAAT---66B.1.6210.000531
S751N751NaaTaaC66P.10.000095
S751N751delAAT---66P.10.000095
S751N751delAAT---66P.1.150.001394
S751N751NaaTaaC55AY.1020.000133
S751N751NaaTaaC55AY.390.000124
S751N751SaAtaGt55AY.430.000022
S751N751NaaTaaC55B.1.10.000091
S751N751YAatTat55B.1.617.20.000019
S751N751IaAtaTt44AY.1030.000025
S751N751TaAtaCt44AY.1030.000025
S751N751TaAtaCt44AY.40.000006
S751N751delAAT---44AY.430.000018
S751N751DAatGat44AY.430.000018
S751N751SaAtaGt44AY.440.000024
S751N751NaaTaaC44AY.840.00175
S751N751NaaTaaC44B.1.1.3060.001754
S751N751IaAtaTt44B.1.1.70.000004
S751N751SaAtaGt44B.1.1600.000125
S751N751DAatGat44B.1.2650.005083
S751N751TaAtaCt33AY.1020.00008
S751N751NaaTaaC33AY.1210.000406
S751N751NaaTaaC33AY.200.000117
S751N751delAAT---33AY.250.000018
S751N751YAatTat33AY.250.000018
S751N751YAatTat33AY.30.00003
S751N751DAatGat33AY.40.000005
S751N751KaaTaaG33AY.4.20.000065
S751N751NaaTaaC33AY.430.000013
S751N751YAatTat33AY.430.000013
S751N751NaaTaaC33AY.470.000093
S751N751NaaTaaC33AY.850.001282
S751N751NaaTaaC33AY.9.20.00011
S751N751YAatTat33B.10.000027
S751N751DAatGat33B.1.1.2220.000612
S751N751DAatGat33B.1.177.210.000229
S751N751SaAtaGt33B.1.20.000026
S751N751SaAtaGt33B.1.3510.000089
S751N751IaAtaTt33B.1.351.20.000908
S751N751NaaTaaC33B.1.3890.003006
S751N751TaAtaCt33B.1.5260.000071
S751N751TaAtaCt33B.1.617.20.000011
S751N751del2aATa--22All0
S751N751delAAT---22AY.1000.000092
S751N751SaAtaGt22AY.250.000012
S751N751NaaTaaC22AY.260.000057
S751N751KaaTaaG22AY.30.00002
S751N751NaaTaaC22AY.330.000134
S751N751KaaTaaG22AY.40.000003
S751N751HAatCat22AY.440.000012
S751N751NaaTaaC22AY.440.000012
S751N751HAatCat22AY.46.30.001867
S751N751SaAtaGt22AY.590.001059
S751N751NaaTaaC22AY.680.000547
S751N751SaAtaGt22AY.700.000417
S751N751NaaTaaC22AY.930.000546
S751N751del1aaTaa-22B0.000256
S751N751delAAT---22B.10.000018
S751N751del1aaTaa-12B.10.000009
S751N751del1Aat-at12B.10.000009
S751N751SaAtaGt22B.1.10.000036
S751N751NaaTaaC22B.1.1.250.001137
S751N751del1aaTaa-22B.1.1.70.000002
S751N751SaAtaGt22B.1.160.80.002577
S751N751SaAtaGt22B.1.1770.000026
S751N751YAatTat22B.1.2580.000133
S751N751NaaTaaC22B.1.2600.006689
S751N751NaaTaaC22B.1.4990.002101
S751N751DAatGat22B.1.5260.000047
S751N751NaaTaaC22B.1.617.10.000258
S751N751HAatCat22B.1.617.20.000008
S751N751KaaTaaG22B.1.617.20.000008
S751N751delAAT---22B.1.617.20.000008
S751N751YAatTat22C.10.004785
S751N751NaaTaaC22C.36.30.001134
S751N751NaaTaaC22P.1.140.000096
S751N751delAAT---22P.1.70.000639
S751N751KaaTaaG22Q.10.000253
S751N751NaaTaaC22Q.10.000253
S751N751KaaTaaG11A0.000387
S751N751DAatGat11A.20.000662
S751N751SaAtaGt11A.270.001656
S751N751AAAtGCt11All0
S751N751EAaTGaA11All0
S751N751delAAT---11AY.100.00053
S751N751NaaTaaC11AY.1000.000046
S751N751YAatTat11AY.1020.000027
S751N751delAAT---11AY.1030.000006
S751N751NaaTaaC11AY.1070.000466
S751N751TaAtaCt11AY.1090.00074
S751N751del1aaTaa-11AY.1170.000085
S751N751NaaTaaC11AY.1170.000085
S751N751YAatTat11AY.1170.000085
S751N751SaAtaGt11AY.1180.000063
S751N751delAAT---11AY.1190.000035
S751N751TaAtaCt11AY.1190.000035
S751N751YAatTat11AY.1200.000037
S751N751KaaTaaA11AY.1200.000037
S751N751HAatCat11AY.1210.000135
S751N751SaAtaGt11AY.1210.000135
S751N751SaAtaGt11AY.130.000161
S751N751KaaTaaG11AY.140.000088
S751N751YAatTat11AY.200.000039
S751N751YAatTat11AY.240.000431
S751N751delAAT---11AY.240.000431
S751N751DAatGat11AY.240.000431
S751N751IaAtaTt11AY.250.000006
S751N751delAAT---11AY.290.000016
S751N751del1aaTaa-11AY.290.000016
S751N751DAatGat11AY.30.00001
S751N751SaAtaGt11AY.30.00001
S751N751delAAT---11AY.34.10.00051
S751N751NaaTaaC11AY.380.000499
S751N751SaAtaGt11AY.390.000025
S751N751TaAtaCt11AY.390.000025
S751N751DAatGat11AY.390.000025
S751N751YAatTat11AY.4.20.000022
S751N751NaaTaaC11AY.4.20.000022
S751N751delAAT---11AY.420.00004
S751N751YAatTat11AY.440.000006
S751N751NaaTaaC11AY.450.000122
S751N751YAatTat11AY.470.000031
S751N751TaAtaCt11AY.580.000907
S751N751KaaTaaG11AY.640.000595
S751N751delAAT---11AY.680.000274
S751N751NaaTaaC11AY.7.20.000559
S751N751NaaTaaC11AY.700.000209
S751N751DAatGat11AY.740.000116
S751N751KaaTaaG11AY.880.000884
S751N751DAatGat11AY.9.20.000037
S751N751NaaTaaC11AY.920.000287
S751N751NaaTaaC11AY.980.000079
S751N751SaAtaGt11AY.98.10.000048
S751N751NaaTaaC11B0.000128
S751N751AAAtGCt11B.10.000009
S751N751SaAtaGt11B.10.000009
S751N751KaaTaaG11B.10.000009
S751N751DAatGat11B.10.000009
S751N751TaAtaCt11B.10.000009
S751N751del1aaTaa-11B.1.10.000018
S751N751SaAtaGt11B.1.1.2200.001859
S751N751NaaTaaC11B.1.1.2210.010101
S751N751YAatTat11B.1.1.2220.000204
S751N751NaaTaaC11B.1.1.2980.000862
S751N751NaaTaaC11B.1.1.3110.000358
S751N751delAAT---11B.1.1.3720.000689
S751N751delAAT---11B.1.1.4090.002833
S751N751NaaTaaC11B.1.1.5190.00004
S751N751DAatGat11B.1.1.5190.00004
S751N751YAatTat11B.1.1.5190.00004
S751N751NaaTaaC11B.1.1.630.000386
S751N751delAAT---11B.1.1.70.000001
S751N751HAatCat11B.1.1.70.000001
S751N751IaAtaTt11B.1.1260.001276
S751N751NaaTaaC11B.1.1600.000031
S751N751DAatGat11B.1.1600.000031
S751N751KaaTaaG11B.1.1690.014925
S751N751NaaTaaC11B.1.177.180.00116
S751N751NaaTaaC11B.1.177.40.000211
S751N751NaaTaaC11B.1.177.440.000519
S751N751DAatGat11B.1.177.520.001757
S751N751NaaTaaC11B.1.177.620.001192
S751N751delAAT---11B.1.20.000009
S751N751YAatTat11B.1.20.000009
S751N751DAatGat11B.1.2210.000071
S751N751EAaTGaA11B.1.2210.000071
S751N751KaaTaaA11B.1.2210.000071
S751N751KaaTaaG11B.1.2230.002778
S751N751NaaTaaC11B.1.2340.000132
S751N751TaAtaCt11B.1.2340.000132
S751N751SaAtaGt11B.1.2430.00007
S751N751KaaTaaG11B.1.2430.00007
S751N751DAatGat11B.1.2580.000067
S751N751NaaTaaC11B.1.258.120.007874
S751N751YAatTat11B.1.258.170.000104
S751N751NaaTaaC11B.1.3060.005714
S751N751NaaTaaC11B.1.3190.003049
S751N751TaAtaCt11B.1.3360.002439
S751N751NaaTaaC11B.1.36.180.00042
S751N751NaaTaaC11B.1.36.290.000517
S751N751KaaTaaG11B.1.36.290.000517
S751N751NaaTaaC11B.1.4000.000429
S751N751YAatTat11B.1.4090.000781
S751N751DAatGat11B.1.4200.010417
S751N751DAatGat11B.1.4290.000024
S751N751NaaTaaC11B.1.466.20.000391
S751N751NaaTaaC11B.1.5080.025641
S751N751NaaTaaC11B.1.5240.001406
S751N751KaaTaaA11B.1.5260.000024
S751N751NaaTaaC11B.1.5270.003704
S751N751delAAT---11B.1.5610.000397
S751N751YAatTat11B.1.5800.004065
S751N751DAatGat11B.1.5950.000261
S751N751del2aATa--11B.1.617.20.000004
S751N751IaAtaTt11B.1.617.20.000004
S751N751SaAtaGt11B.1.617.20.000004
S751N751DAatGat11B.1.617.20.000004
S751N751delAAT---11B.1.6200.000946
S751N751delAAT---11B.1.621.10.000506
S751N751IaAtaTt11B.1.6370.000073
S751N751delAAT---11B.1.6380.052632
S751N751NaaTaaC11B.450.003831
S751N751NaaTaaC11C.370.000116
S751N751SaAtaGt11C.370.000116
S751N751YAatTat11C.370.000116
S751N751DAatGat11N.40.004255
S751N751del2aATa--11P.10.000016
S751N751delAAT---11P.1.130.000898
S751N751KaaTaaG11P.1.140.000048
S751N751TaAtaCt11P.1.140.000048
S751N751delAAT---11Q.80.000165
S751N751KaaTaaG11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.