CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 688 | A688S | nonsyn | Gct | Tct | 1176 | 1172 | 0.996599 | 23624-23626 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 688 | A688S | Gct | Tct | 1172 | 1176 | All | 0.000224 |
S | 688 | A688S | Gct | Tct | 144 | 145 | B.1.1.7 | 0.000129 |
S | 688 | A688S | Gct | Tct | 142 | 142 | AY.4 | 0.000221 |
S | 688 | A688S | Gct | Tct | 125 | 125 | AY.43 | 0.000554 |
S | 688 | A688S | Gct | Tct | 125 | 125 | B.1.1.294 | 0.158228 |
S | 688 | A688S | Gct | Tct | 65 | 65 | B.1.526 | 0.001528 |
S | 688 | A688S | Gct | Tct | 58 | 59 | B.1.617.2 | 0.000218 |
S | 688 | A688S | Gct | Tct | 43 | 43 | M.1 | 1 |
S | 688 | A688S | Gct | Tct | 35 | 35 | B.1.2 | 0.000308 |
S | 688 | A688S | Gct | Tct | 31 | 31 | B.1.160 | 0.000967 |
S | 688 | A688S | Gct | Tct | 29 | 29 | B.1.258.17 | 0.003015 |
S | 688 | A688S | Gct | Tct | 25 | 25 | P.1 | 0.000394 |
S | 688 | A688S | Gct | Tct | 18 | 18 | AY.119 | 0.000636 |
S | 688 | A688S | Gct | Tct | 18 | 18 | B.1.1 | 0.000327 |
S | 688 | A688S | Gct | Tct | 16 | 16 | AY.103 | 0.000099 |
S | 688 | A688S | Gct | Tct | 13 | 13 | AY.4.5 | 0.001397 |
S | 688 | A688S | Gct | Tct | 12 | 12 | B.1 | 0.00011 |
S | 688 | A688S | Gct | Tct | 11 | 12 | B.1.351 | 0.000327 |
S | 688 | A688S | Gct | Tct | 10 | 10 | AY.46.5 | 0.001984 |
S | 688 | A688S | Gct | Tct | 9 | 9 | AY.102 | 0.000239 |
S | 688 | A688S | Gct | Tct | 9 | 9 | AY.5 | 0.000186 |
S | 688 | A688S | Gct | Tct | 7 | 7 | AY.44 | 0.000043 |
S | 688 | A688S | Gct | Tct | 7 | 7 | B.1.428 | 0.007143 |
S | 688 | A688S | Gct | Tct | 7 | 7 | B.1.429 | 0.000165 |
S | 688 | A688S | Gct | Tct | 7 | 7 | C.1.1 | 0.538462 |
S | 688 | A688S | Gct | Tct | 6 | 6 | AY.100 | 0.000276 |
S | 688 | A688S | Gct | Tct | 6 | 6 | B.1.177.33 | 0.009868 |
S | 688 | A688S | Gct | Tct | 6 | 6 | P.1.14 | 0.000287 |
S | 688 | A688S | Gct | Tct | 5 | 5 | AY.98.1 | 0.000242 |
S | 688 | A688S | Gct | Tct | 5 | 5 | B.1.1.28 | 0.001556 |
S | 688 | A688S | Gct | Tct | 5 | 5 | B.1.1.306 | 0.002192 |
S | 688 | A688S | Gct | Tct | 5 | 5 | B.1.1.519 | 0.000199 |
S | 688 | A688S | Gct | Tct | 5 | 5 | B.1.36.8 | 0.005 |
S | 688 | A688S | Gct | Tct | 5 | 5 | W.1 | 0.043478 |
S | 688 | A688S | Gct | Tct | 4 | 4 | AY.118 | 0.000251 |
S | 688 | A688S | Gct | Tct | 4 | 4 | AY.20 | 0.000155 |
S | 688 | A688S | Gct | Tct | 4 | 4 | AY.25 | 0.000024 |
S | 688 | A688S | Gct | Tct | 4 | 4 | AY.29 | 0.000063 |
S | 688 | A688S | Gct | Tct | 4 | 4 | B.1.1.352 | 0.125 |
S | 688 | A688S | Gct | Tct | 4 | 4 | B.1.258 | 0.000266 |
S | 688 | A688S | Gct | Tct | 4 | 4 | B.1.306 | 0.022857 |
S | 688 | A688S | Gct | Tct | 4 | 4 | C.37 | 0.000464 |
S | 688 | A688S | Gct | Tct | 4 | 4 | P.1.17 | 0.000647 |
S | 688 | A688S | Gct | Tct | 3 | 3 | AY.26 | 0.000085 |
S | 688 | A688S | Gct | Tct | 3 | 3 | AY.27 | 0.000194 |
S | 688 | A688S | Gct | Tct | 3 | 3 | AY.34 | 0.000291 |
S | 688 | A688S | Gct | Tct | 3 | 3 | AY.5.3 | 0.001012 |
S | 688 | A688S | Gct | Tct | 3 | 3 | AY.57 | 0.001969 |
S | 688 | A688S | Gct | Tct | 3 | 3 | AY.75.1 | 0.000541 |
S | 688 | A688S | Gct | Tct | 3 | 3 | B.1.177 | 0.00004 |
S | 688 | A688S | Gct | Tct | 3 | 3 | B.1.36 | 0.000438 |
S | 688 | A688S | Gct | Tct | 3 | 3 | B.1.595 | 0.000783 |
S | 688 | A688S | Gct | Tct | 3 | 3 | B.1.637 | 0.000219 |
S | 688 | A688S | Gct | Tct | 3 | 3 | C.36 | 0.002732 |
S | 688 | A688S | Gct | Tct | 3 | 3 | P.1.15 | 0.000697 |
S | 688 | A688S | Gct | Tct | 2 | 2 | A.2.5 | 0.000998 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.120 | 0.000074 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.23 | 0.000139 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.3.1 | 0.000171 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.34.1 | 0.00102 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.36 | 0.000296 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.39 | 0.000049 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.4.2 | 0.000043 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.58 | 0.001815 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.61 | 0.00021 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.9 | 0.000135 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.91 | 0.001461 |
S | 688 | A688S | Gct | Tct | 2 | 2 | AY.92 | 0.000575 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.1.500 | 0.04 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.234 | 0.000264 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.258.24 | 0.021505 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.36.24 | 0.012346 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.466.2 | 0.000782 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.469 | 0.00722 |
S | 688 | A688S | Gct | Tct | 2 | 2 | B.1.621 | 0.000177 |
S | 688 | A688S | Gct | Tct | 2 | 2 | P.7 | 0.008734 |
S | 688 | A688S | Gct | Tct | 2 | 2 | R.1 | 0.00018 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.12 | 0.000316 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.17 | 0.008197 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.23.1 | 0.000417 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.3 | 0.00001 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.33 | 0.000067 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.37 | 0.000316 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.39.1 | 0.00004 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.46 | 0.000104 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.46.6 | 0.000072 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.55 | 0.000917 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.63 | 0.000387 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.69 | 0.000187 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.74 | 0.000116 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.8 | 0.000606 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.86 | 0.00083 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.87 | 0.000833 |
S | 688 | A688S | Gct | Tct | 1 | 1 | AY.9.1 | 0.000084 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.1.263 | 0.001558 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.1.290 | 0.018182 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.1.305 | 0.003861 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.1.37 | 0.000193 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.1.376 | 0.005952 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.177.44 | 0.000519 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.177.73 | 0.000566 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.221 | 0.000071 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.36.26 | 0.002857 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.36.37 | 0.002778 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.393 | 0.028571 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.427 | 0.00005 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.459 | 0.004082 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.524 | 0.001406 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.599 | 0.00365 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.621.1 | 0.000506 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.625 | 0.002353 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.1.8 | 0.001972 |
S | 688 | A688S | Gct | Tct | 1 | 1 | B.40 | 0.000364 |
S | 688 | A688S | Gct | Tct | 1 | 1 | C.1 | 0.002392 |
S | 688 | A688S | Gct | Tct | 1 | 1 | K.1 | 0.02381 |
S | 688 | A688S | Gct | Tct | 1 | 1 | P.1.12 | 0.000484 |
S | 688 | A688S | Gct | Tct | 1 | 1 | P.1.17.1 | 0.000875 |
S | 688 | A688S | Gct | Tct | 1 | 1 | P.1.9 | 0.004808 |
S | 688 | A688S | Gct | Tct | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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