CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 684 | A684V | nonsyn | gCa | gTa | 3852 | 3852 | 1 | 23612-23614 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 684 | A684V | gCa | gTa | 3852 | 3852 | All | 0.000737 |
S | 684 | A684V | gCa | gTa | 931 | 931 | B.1.1.7 | 0.000833 |
S | 684 | A684V | gCa | gTa | 594 | 594 | AY.4 | 0.000925 |
S | 684 | A684V | gCa | gTa | 314 | 314 | B.1.617.2 | 0.001182 |
S | 684 | A684V | gCa | gTa | 209 | 209 | AY.43 | 0.000926 |
S | 684 | A684V | gCa | gTa | 166 | 166 | AY.25 | 0.000998 |
S | 684 | A684V | gCa | gTa | 143 | 143 | AY.103 | 0.000888 |
S | 684 | A684V | gCa | gTa | 107 | 107 | AY.119 | 0.003778 |
S | 684 | A684V | gCa | gTa | 100 | 100 | B.1.2 | 0.000881 |
S | 684 | A684V | gCa | gTa | 89 | 89 | B.1.36.18 | 0.037395 |
S | 684 | A684V | gCa | gTa | 81 | 81 | AY.3 | 0.000806 |
S | 684 | A684V | gCa | gTa | 72 | 72 | AY.35 | 0.016779 |
S | 684 | A684V | gCa | gTa | 51 | 51 | P.1 | 0.000803 |
S | 684 | A684V | gCa | gTa | 48 | 48 | AY.44 | 0.000292 |
S | 684 | A684V | gCa | gTa | 44 | 44 | AD.2 | 0.009634 |
S | 684 | A684V | gCa | gTa | 40 | 40 | AY.54 | 0.003814 |
S | 684 | A684V | gCa | gTa | 37 | 37 | B.1 | 0.000339 |
S | 684 | A684V | gCa | gTa | 35 | 35 | Q.3 | 0.005076 |
S | 684 | A684V | gCa | gTa | 30 | 30 | AY.100 | 0.00138 |
S | 684 | A684V | gCa | gTa | 30 | 30 | B.1.221 | 0.002131 |
S | 684 | A684V | gCa | gTa | 28 | 28 | B.1.177 | 0.000369 |
S | 684 | A684V | gCa | gTa | 25 | 25 | B.1.427 | 0.001262 |
S | 684 | A684V | gCa | gTa | 24 | 24 | B.1.1 | 0.000435 |
S | 684 | A684V | gCa | gTa | 22 | 22 | B.1.429 | 0.000518 |
S | 684 | A684V | gCa | gTa | 21 | 21 | AY.42 | 0.000845 |
S | 684 | A684V | gCa | gTa | 21 | 21 | B.1.243 | 0.001461 |
S | 684 | A684V | gCa | gTa | 20 | 20 | P.1.14 | 0.000956 |
S | 684 | A684V | gCa | gTa | 19 | 19 | C.37 | 0.002205 |
S | 684 | A684V | gCa | gTa | 18 | 18 | B.1.411 | 0.066667 |
S | 684 | A684V | gCa | gTa | 17 | 17 | AY.29 | 0.000268 |
S | 684 | A684V | gCa | gTa | 15 | 15 | AY.102 | 0.000398 |
S | 684 | A684V | gCa | gTa | 15 | 15 | B.1.160 | 0.000468 |
S | 684 | A684V | gCa | gTa | 15 | 15 | B.1.362.1 | 1 |
S | 684 | A684V | gCa | gTa | 13 | 13 | B.1.1.519 | 0.000516 |
S | 684 | A684V | gCa | gTa | 12 | 12 | AY.39.1 | 0.000475 |
S | 684 | A684V | gCa | gTa | 12 | 12 | AY.4.2 | 0.00026 |
S | 684 | A684V | gCa | gTa | 12 | 12 | AY.9.2 | 0.000441 |
S | 684 | A684V | gCa | gTa | 12 | 12 | B.1.1.486 | 0.018927 |
S | 684 | A684V | gCa | gTa | 12 | 12 | C.36.3 | 0.006807 |
S | 684 | A684V | gCa | gTa | 11 | 11 | B.1.351 | 0.000327 |
S | 684 | A684V | gCa | gTa | 10 | 10 | AY.16.1 | 0.004699 |
S | 684 | A684V | gCa | gTa | 10 | 10 | AY.47 | 0.000311 |
S | 684 | A684V | gCa | gTa | 10 | 10 | AY.5 | 0.000206 |
S | 684 | A684V | gCa | gTa | 10 | 10 | B.1.258.17 | 0.00104 |
S | 684 | A684V | gCa | gTa | 10 | 10 | B.1.509 | 0.008658 |
S | 684 | A684V | gCa | gTa | 8 | 8 | B.1.1.214 | 0.000444 |
S | 684 | A684V | gCa | gTa | 8 | 8 | B.1.526 | 0.000188 |
S | 684 | A684V | gCa | gTa | 7 | 7 | AY.116 | 0.002007 |
S | 684 | A684V | gCa | gTa | 7 | 7 | AY.4.5 | 0.000752 |
S | 684 | A684V | gCa | gTa | 6 | 6 | AY.98.1 | 0.000291 |
S | 684 | A684V | gCa | gTa | 6 | 6 | B.1.1.28 | 0.001867 |
S | 684 | A684V | gCa | gTa | 6 | 6 | B.1.561 | 0.002382 |
S | 684 | A684V | gCa | gTa | 6 | 6 | D.2 | 0.00045 |
S | 684 | A684V | gCa | gTa | 6 | 6 | P.1.7 | 0.001916 |
S | 684 | A684V | gCa | gTa | 5 | 5 | AY.117 | 0.000423 |
S | 684 | A684V | gCa | gTa | 5 | 5 | AY.26 | 0.000142 |
S | 684 | A684V | gCa | gTa | 5 | 5 | AY.39 | 0.000124 |
S | 684 | A684V | gCa | gTa | 5 | 5 | AY.92 | 0.001436 |
S | 684 | A684V | gCa | gTa | 5 | 5 | B.1.1.189 | 0.007564 |
S | 684 | A684V | gCa | gTa | 5 | 5 | B.1.1.70 | 0.001705 |
S | 684 | A684V | gCa | gTa | 5 | 5 | B.1.577 | 0.003436 |
S | 684 | A684V | gCa | gTa | 5 | 5 | B.1.596 | 0.000436 |
S | 684 | A684V | gCa | gTa | 5 | 5 | B.1.617.1 | 0.000645 |
S | 684 | A684V | gCa | gTa | 4 | 4 | AY.120 | 0.000149 |
S | 684 | A684V | gCa | gTa | 4 | 4 | AY.46 | 0.000416 |
S | 684 | A684V | gCa | gTa | 4 | 4 | AY.98 | 0.000316 |
S | 684 | A684V | gCa | gTa | 4 | 4 | B.1.1.1 | 0.001307 |
S | 684 | A684V | gCa | gTa | 4 | 4 | B.1.1.33 | 0.001684 |
S | 684 | A684V | gCa | gTa | 4 | 4 | B.1.177.21 | 0.000306 |
S | 684 | A684V | gCa | gTa | 4 | 4 | B.1.177.86 | 0.000734 |
S | 684 | A684V | gCa | gTa | 4 | 4 | B.1.525 | 0.000453 |
S | 684 | A684V | gCa | gTa | 4 | 4 | P.1.17 | 0.000647 |
S | 684 | A684V | gCa | gTa | 3 | 3 | AY.113 | 0.000427 |
S | 684 | A684V | gCa | gTa | 3 | 3 | AY.13 | 0.000483 |
S | 684 | A684V | gCa | gTa | 3 | 3 | AY.20 | 0.000117 |
S | 684 | A684V | gCa | gTa | 3 | 3 | AY.33 | 0.0002 |
S | 684 | A684V | gCa | gTa | 3 | 3 | AY.45 | 0.000365 |
S | 684 | A684V | gCa | gTa | 3 | 3 | AY.48 | 0.001395 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.1.317 | 0.001235 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.1.337 | 0.010791 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.1.398 | 0.009677 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.177.77 | 0.002179 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.36.8 | 0.003 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.438.1 | 0.000322 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.517 | 0.001281 |
S | 684 | A684V | gCa | gTa | 3 | 3 | B.1.621 | 0.000266 |
S | 684 | A684V | gCa | gTa | 3 | 3 | C.4 | 0.03 |
S | 684 | A684V | gCa | gTa | 3 | 3 | P.2 | 0.00056 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.121 | 0.000271 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.19 | 0.002281 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.24 | 0.000862 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.3.1 | 0.000171 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.46.4 | 0.000329 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.6 | 0.000082 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.68 | 0.000547 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.75 | 0.000112 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.9 | 0.000135 |
S | 684 | A684V | gCa | gTa | 2 | 2 | AY.9.1 | 0.000167 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.241 | 0.004141 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.251 | 0.015873 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.291 | 0.001485 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.306 | 0.000877 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.369 | 0.000892 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.433 | 0.002849 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.1.71 | 0.012121 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.158 | 0.047619 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.160.27 | 0.030303 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.177.12 | 0.000303 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.177.19 | 0.002861 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.177.44 | 0.001038 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.206 | 0.001631 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.234 | 0.000264 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.240 | 0.000431 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.258 | 0.000133 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.258.24 | 0.021505 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.369 | 0.00057 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.499 | 0.002101 |
S | 684 | A684V | gCa | gTa | 2 | 2 | B.1.637 | 0.000146 |
S | 684 | A684V | gCa | gTa | 2 | 2 | P.1.15 | 0.000465 |
S | 684 | A684V | gCa | gTa | 2 | 2 | P.3 | 0.00319 |
S | 684 | A684V | gCa | gTa | 2 | 2 | Q.1 | 0.000253 |
S | 684 | A684V | gCa | gTa | 1 | 1 | A.23.1 | 0.000704 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.101 | 0.00049 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.107 | 0.000466 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.11 | 0.001339 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.115 | 0.005208 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.14 | 0.000088 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.15 | 0.002222 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.16 | 0.00038 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.27 | 0.000065 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.30 | 0.000396 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.34.1 | 0.00051 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.40 | 0.000964 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.46.5 | 0.000198 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.5.3 | 0.000337 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.5.4 | 0.000277 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.55 | 0.000917 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.57 | 0.000656 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.61 | 0.000105 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.67 | 0.000464 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.7.1 | 0.000113 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.74 | 0.000116 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.75.1 | 0.00018 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.80 | 0.001129 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.84 | 0.000437 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.86 | 0.00083 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.88 | 0.000884 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.91 | 0.00073 |
S | 684 | A684V | gCa | gTa | 1 | 1 | AY.99.2 | 0.000092 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B | 0.000128 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.204 | 0.00304 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.220 | 0.001859 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.222 | 0.000204 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.229 | 0.005747 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.25 | 0.000569 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.256 | 0.013699 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.263 | 0.001558 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.269 | 0.001353 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.277 | 0.000759 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.284 | 0.000107 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.37 | 0.000193 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.381 | 0.04 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.4 | 0.002976 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.432 | 0.001266 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.1.50 | 0.000679 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.131 | 0.008772 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.157 | 0.002985 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.160.17 | 0.001701 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.160.28 | 0.002924 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.177.32 | 0.00135 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.177.4 | 0.000211 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.177.73 | 0.000566 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.177.76 | 0.002494 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.177.81 | 0.000189 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.210 | 0.002132 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.264 | 0.012346 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.293 | 0.0125 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.3 | 0.002618 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.311 | 0.000275 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.349 | 0.000715 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.36 | 0.000146 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.36.12 | 0.009615 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.36.29 | 0.000517 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.362 | 0.001541 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.416 | 0.001269 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.465 | 0.003802 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.466.2 | 0.000391 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.470 | 0.001404 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.499.1 | 0.111111 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.527 | 0.003704 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.564.1 | 0.001577 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.620 | 0.000946 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.628 | 0.000352 |
S | 684 | A684V | gCa | gTa | 1 | 1 | B.1.631 | 0.003367 |
S | 684 | A684V | gCa | gTa | 1 | 1 | C.14 | 0.004329 |
S | 684 | A684V | gCa | gTa | 1 | 1 | C.35 | 0.000774 |
S | 684 | A684V | gCa | gTa | 1 | 1 | N.5 | 0.001767 |
S | 684 | A684V | gCa | gTa | 1 | 1 | P.1.12 | 0.000484 |
S | 684 | A684V | gCa | gTa | 1 | 1 | P.1.2 | 0.001156 |
S | 684 | A684V | gCa | gTa | 1 | 1 | Q.4 | 0.000455 |
S | 684 | A684V | gCa | gTa | 1 | 1 | Q.8 | 0.000165 |
S | 684 | A684V | gCa | gTa | 1 | 1 | W.1 | 0.008696 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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