CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 679 & Codon = aaA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	679	N679K		nonsyn	aaT	aaA	4948	2949	0.595998	23597-23599

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	679	N679K	aaT	aaA	2949	4948	All	0.000564
S	679	N679K	aaT	aaA	52	717	B.1.2	0.000458
S	679	N679K	aaT	aaA	684	684	P.1.12	0.331075
S	679	N679K	aaT	aaA	609	609	B.1.1.433	0.867521
S	679	N679K	aaT	aaA	253	281	B.1.1	0.00459
S	679	N679K	aaT	aaA	254	254	B.1.111	0.298472
S	679	N679K	aaT	aaA	249	249	B.1.234	0.032854
S	679	N679K	aaT	aaA	210	210	C.1.2	0.893617
S	679	N679K	aaT	aaA	84	86	B.1.258	0.00559
S	679	N679K	aaT	aaA	58	85	B.1	0.000531
S	679	N679K	aaT	aaA	56	64	P.1	0.000882
S	679	N679K	aaT	aaA	63	63	B.1.1.28	0.019608
S	679	N679K	aaT	aaA	42	42	B.1.9.5	0.238636
S	679	N679K	aaT	aaA	26	41	B.1.1.7	0.000023
S	679	N679K	aaT	aaA	29	29	C.36.3.1	0.078804
S	679	N679K	aaT	aaA	22	22	B.1.214.2	0.013189
S	679	N679K	aaT	aaA	20	20	B.1.1.203	0.338983
S	679	N679K	aaT	aaA	20	20	B.1.560	0.092593
S	679	N679K	aaT	aaA	18	18	B.1.1.1	0.00588
S	679	N679K	aaT	aaA	16	16	B.1.177	0.000211
S	679	N679K	aaT	aaA	12	16	C.37	0.001393
S	679	N679K	aaT	aaA	15	15	K.2	0.6
S	679	N679K	aaT	aaA	14	14	B.1.470	0.019663
S	679	N679K	aaT	aaA	13	13	P.1.5	1
S	679	N679K	aaT	aaA	5	10	B.1.36	0.00073
S	679	N679K	aaT	aaA	8	8	B.1.1.291	0.005939
S	679	N679K	aaT	aaA	6	6	B.1.1.317	0.00247
S	679	N679K	aaT	aaA	6	6	B.1.1.382	0.214286
S	679	N679K	aaT	aaA	1	5	B.1.1.25	0.000569
S	679	N679K	aaT	aaA	5	5	B.1.1.372	0.003444
S	679	N679K	aaT	aaA	4	4	B.1.540	0.038835
S	679	N679K	aaT	aaA	2	3		0.111111
S	679	N679K	aaT	aaA	3	3	B.1.1.153	0.003286
S	679	N679K	aaT	aaA	3	3	B.1.1.216	0.002671
S	679	N679K	aaT	aaA	3	3	B.1.1.54	0.009063
S	679	N679K	aaT	aaA	3	3	B.1.177.60	0.000655
S	679	N679K	aaT	aaA	3	3	B.1.221	0.000213
S	679	N679K	aaT	aaA	3	3	B.1.258.3	0.005025
S	679	N679K	aaT	aaA	3	3	B.1.429	0.000071
S	679	N679K	aaT	aaA	2	3	B.1.525	0.000226
S	679	N679K	aaT	aaA	1	2	A	0.000387
S	679	N679K	aaT	aaA	2	2	AY.20	0.000078
S	679	N679K	aaT	aaA	2	2	B.1.1.148	0.017544
S	679	N679K	aaT	aaA	2	2	B.1.1.161	0.007067
S	679	N679K	aaT	aaA	2	2	B.1.1.198	0.002937
S	679	N679K	aaT	aaA	2	2	B.1.1.306	0.000877
S	679	N679K	aaT	aaA	2	2	B.1.1.453	0.016949
S	679	N679K	aaT	aaA	2	2	B.1.1.464	0.002946
S	679	N679K	aaT	aaA	2	2	B.1.177.23	0.006472
S	679	N679K	aaT	aaA	1	2	B.1.243	0.00007
S	679	N679K	aaT	aaA	1	2	B.1.351	0.00003
S	679	N679K	aaT	aaA	1	2	B.1.427	0.00005
S	679	N679K	aaT	aaA	1	2	B.1.456	0.003268
S	679	N679K	aaT	aaA	2	2	B.1.466.2	0.000782
S	679	N679K	aaT	aaA	2	2	C.1	0.004785
S	679	N679K	aaT	aaA	2	2	P.1.15	0.000465
S	679	N679K	aaT	aaA	1	1	AB.1	0.008197
S	679	N679K	aaT	aaA	1	1	AY.102	0.000027
S	679	N679K	aaT	aaA	1	1	AY.39	0.000025
S	679	N679K	aaT	aaA	1	1	AY.4	0.000002
S	679	N679K	aaT	aaA	1	1	AY.44	0.000006
S	679	N679K	aaT	aaA	1	1	AY.46	0.000104
S	679	N679K	aaT	aaA	1	1	AY.47	0.000031
S	679	N679K	aaT	aaA	1	1	AY.61	0.000105
S	679	N679K	aaT	aaA	1	1	AY.67	0.000464
S	679	N679K	aaT	aaA	1	1	B.1.1.117	0.009709
S	679	N679K	aaT	aaA	1	1	B.1.1.220	0.001859
S	679	N679K	aaT	aaA	1	1	B.1.1.243	0.004082
S	679	N679K	aaT	aaA	1	1	B.1.1.277	0.000759
S	679	N679K	aaT	aaA	1	1	B.1.1.31	0.066667
S	679	N679K	aaT	aaA	1	1	B.1.1.37	0.000193
S	679	N679K	aaT	aaA	1	1	B.1.1.39	0.00051
S	679	N679K	aaT	aaA	1	1	B.1.1.402	0.011111
S	679	N679K	aaT	aaA	1	1	B.1.1.419	0.007407
S	679	N679K	aaT	aaA	1	1	B.1.1.432	0.001266
S	679	N679K	aaT	aaA	1	1	B.1.1.523	0.001563
S	679	N679K	aaT	aaA	1	1	B.1.1.99	0.02381
S	679	N679K	aaT	aaA	1	1	B.1.158	0.02381
S	679	N679K	aaT	aaA	1	1	B.1.160	0.000031
S	679	N679K	aaT	aaA	1	1	B.1.160.32	0.004292
S	679	N679K	aaT	aaA	1	1	B.1.177.21	0.000076
S	679	N679K	aaT	aaA	1	1	B.1.177.86	0.000183
S	679	N679K	aaT	aaA	1	1	B.1.258.14	0.00098
S	679	N679K	aaT	aaA	1	1	B.1.284	0.013158
S	679	N679K	aaT	aaA	1	1	B.1.349	0.000715
S	679	N679K	aaT	aaA	1	1	B.1.36.29	0.000517
S	679	N679K	aaT	aaA	1	1	B.1.36.34	0.021277
S	679	N679K	aaT	aaA	1	1	B.1.408	0.00369
S	679	N679K	aaT	aaA	1	1	B.1.468	0.005714
S	679	N679K	aaT	aaA	1	1	B.1.497	0.000315
S	679	N679K	aaT	aaA	1	1	B.1.509	0.000866
S	679	N679K	aaT	aaA	1	1	B.1.561	0.000397
S	679	N679K	aaT	aaA	1	1	B.1.595	0.000261
S	679	N679K	aaT	aaA	1	1	B.1.617.1	0.000129
S	679	N679K	aaT	aaA	1	1	B.1.618	0.004032
S	679	N679K	aaT	aaA	1	1	B.1.619	0.000871
S	679	N679K	aaT	aaA	1	1	B.52	0.010101
S	679	N679K	aaT	aaA	1	1	C.35	0.000774
S	679	N679K	aaT	aaA	1	1	N.5	0.001767

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.