CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 677

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	677	Q677H		nonsyn	caG	caT	57213	30807	0.538462	23591-23593
S	677	Q677H		nonsyn	caG	caC	57213	26406	0.461538	23591-23593
S	677	Q677P		nonsyn	cAg	cCg	5516	5506	0.998187	23591-23593
S	677	Q677P		nonsyn	cAG	cCT	5516	9	0.00163162	23591-23593
S	677	Q677P		nonsyn	cAG	cCC	5516	1	0.000181291	23591-23593
S	677	Q677R		nonsyn	cAg	cGg	783	763	0.974457	23591-23593
S	677	Q677R		nonsyn	cAG	cGC	783	18	0.0229885	23591-23593
S	677	Q677R		nonsyn	cAG	cGA	783	2	0.00255428	23591-23593
S	677	Q677Q		syn	caG	caA	407	407	1	23591-23593
S	677	Q677L		nonsyn	cAg	cTg	212	210	0.990566	23591-23593
S	677	Q677L		nonsyn	cAG	cTA	212	2	0.00943396	23591-23593
S	677	Q677K		nonsyn	Cag	Aag	175	174	0.994286	23591-23593
S	677	Q677K		nonsyn	CaG	AaA	175	1	0.00571429	23591-23593
S	677	Q677del		del	CAG	---	166	166	1	23591-23593
S	677	Q677X		nonsyn	Cag	Tag	23	22	0.956522	23591-23593
S	677	Q677X		nonsyn	CaG	TaA	23	1	0.0434783	23591-23593
S	677	Q677Y		nonsyn	CaG	TaC	20	10	0.5	23591-23593
S	677	Q677Y		nonsyn	CaG	TaT	20	10	0.5	23591-23593
S	677	Q677E		nonsyn	Cag	Gag	7	7	1	23591-23593
S	677	Q677del1		del	Cag	-ag	3	2	0.666667	23591-23593
S	677	Q677del1		del	cAg	c-g	3	1	0.333333	23591-23593
S	677	Q677N		nonsyn	CaG	AaT	1	1	1	23591-23593
S	677	Q677W		nonsyn	CAg	TGg	1	1	1	23591-23593
S	677	Q677del2		del	cAG	c--	1	1	1	23591-23593
S	677	Q677S		nonsyn	CAg	TCg	1	1	1	23591-23593

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	677	Q677H	caG	caT	30807	57213	All	0.005892
S	677	Q677H	caG	caC	26406	57213	All	0.00505
S	677	Q677H	caG	caT	10258	11076	B.1.2	0.090326
S	677	Q677H	caG	caC	818	11076	B.1.2	0.007203
S	677	Q677H	caG	caC	10131	10138	AY.34	0.982352
S	677	Q677H	caG	caT	7	10138	AY.34	0.000679
S	677	Q677H	caG	caC	8780	8785	B.1.525	0.99355
S	677	Q677H	caG	caT	5	8785	B.1.525	0.000566
S	677	Q677P	cAg	cCg	5506	5516	All	0.001053
S	677	Q677P	cAG	cCT	9	5516	All	0.000002
S	677	Q677P	cAG	cCC	1	5516	All	0
S	677	Q677P	cAg	cCg	5103	5110	B.1.596	0.444667
S	677	Q677P	cAG	cCT	7	5110	B.1.596	0.00061
S	677	Q677H	caG	caT	3425	4286	B.1.1.7	0.003066
S	677	Q677H	caG	caC	861	4286	B.1.1.7	0.000771
S	677	Q677H	caG	caT	1736	1736	C.36.3	0.984685
S	677	Q677H	caG	caC	560	1070	B.1.617.2	0.002109
S	677	Q677H	caG	caT	510	1070	B.1.617.2	0.00192
S	677	Q677H	caG	caC	1061	1061	B.1.1.316	0.981499
S	677	Q677H	caG	caT	1018	1019	B.1.234	0.134319
S	677	Q677H	caG	caC	1	1019	B.1.234	0.000132
S	677	Q677H	caG	caT	1011	1011	B.1.1.70	0.344816
S	677	Q677H	caG	caT	799	959	B.1.36	0.116574
S	677	Q677H	caG	caC	160	959	B.1.36	0.023344
S	677	Q677H	caG	caT	713	924	B.1	0.006531
S	677	Q677H	caG	caC	211	924	B.1	0.001933
S	677	Q677H	caG	caC	909	911	AY.34.1	0.463539
S	677	Q677H	caG	caT	2	911	AY.34.1	0.00102
S	677	Q677H	caG	caT	892	892	C.36	0.812386
S	677	Q677H	caG	caT	567	888	AY.43	0.002512
S	677	Q677H	caG	caC	321	888	AY.43	0.001422
S	677	Q677R	cAg	cGg	763	783	All	0.000146
S	677	Q677R	cAG	cGC	18	783	All	0.000003
S	677	Q677R	cAG	cGA	2	783	All	0
S	677	Q677H	caG	caT	627	686	AY.44	0.003816
S	677	Q677H	caG	caC	59	686	AY.44	0.000359
S	677	Q677H	caG	caT	513	623	AY.4	0.000798
S	677	Q677H	caG	caC	110	623	AY.4	0.000171
S	677	Q677H	caG	caT	616	616	B.1.1.486	0.971609
S	677	Q677H	caG	caT	542	542	B.1.1.284	0.058211
S	677	Q677H	caG	caT	452	507	AY.103	0.002806
S	677	Q677H	caG	caC	55	507	AY.103	0.000341
S	677	Q677H	caG	caT	477	477	B.1.1.420	0.479879
S	677	Q677Q	caG	caA	407	407	All	0.000078
S	677	Q677H	caG	caT	279	401	P.1	0.004395
S	677	Q677H	caG	caC	122	401	P.1	0.001922
S	677	Q677H	caG	caC	332	394	AY.102	0.008803
S	677	Q677H	caG	caT	62	394	AY.102	0.001644
S	677	Q677H	caG	caT	264	333	B.1.1	0.004789
S	677	Q677H	caG	caC	69	333	B.1.1	0.001252
S	677	Q677H	caG	caT	327	327	C.36.3.1	0.888587
S	677	Q677H	caG	caT	313	325	AY.3	0.003113
S	677	Q677H	caG	caC	12	325	AY.3	0.000119
S	677	Q677H	caG	caT	317	320	B.1.526	0.007451
S	677	Q677H	caG	caC	3	320	B.1.526	0.000071
S	677	Q677H	caG	caT	305	305	P.6	0.959119
S	677	Q677H	caG	caC	164	251	B.1.351	0.004875
S	677	Q677H	caG	caT	87	251	B.1.351	0.002586
S	677	Q677H	caG	caT	241	241	C.36.1	1
S	677	Q677H	caG	caT	201	236	B.1.177	0.002647
S	677	Q677H	caG	caC	35	236	B.1.177	0.000461
S	677	Q677L	cAg	cTg	210	212	All	0.00004
S	677	Q677L	cAG	cTA	2	212	All	0
S	677	Q677H	caG	caT	212	212	B.1.241	0.172078
S	677	Q677H	caG	caC	184	205	AY.9.1	0.015405
S	677	Q677H	caG	caT	21	205	AY.9.1	0.001758
S	677	Q677H	caG	caT	171	181	B.1.160	0.005333
S	677	Q677H	caG	caC	10	181	B.1.160	0.000312
S	677	Q677P	cAg	cCg	176	178	B.1.2	0.00155
S	677	Q677P	cAG	cCT	2	178	B.1.2	0.000018
S	677	Q677K	Cag	Aag	174	175	All	0.000033
S	677	Q677K	CaG	AaA	1	175	All	0
S	677	Q677H	caG	caC	116	171	B.1.427	0.005858
S	677	Q677H	caG	caT	55	171	B.1.427	0.002777
S	677	Q677del	CAG	---	166	166	All	0.000032
S	677	Q677H	caG	caT	142	150	AY.98.1	0.006877
S	677	Q677H	caG	caC	8	150	AY.98.1	0.000387
S	677	Q677L	cAg	cTg	145	145	B.1.1.7	0.00013
S	677	Q677Q	caG	caA	137	137	B.1.1.7	0.000123
S	677	Q677H	caG	caT	134	136	AY.25	0.000806
S	677	Q677H	caG	caC	2	136	AY.25	0.000012
S	677	Q677Q	caG	caA	136	136	AY.4	0.000212
S	677	Q677H	caG	caT	126	136	B.1.596	0.010979
S	677	Q677H	caG	caC	10	136	B.1.596	0.000871
S	677	Q677R	cAg	cGg	135	135	B.1.1.7	0.000121
S	677	Q677H	caG	caT	133	133	A.27	0.220199
S	677	Q677H	caG	caC	111	133	AY.39	0.002743
S	677	Q677H	caG	caT	22	133	AY.39	0.000544
S	677	Q677H	caG	caT	124	125	B.1.265	0.15756
S	677	Q677H	caG	caC	1	125	B.1.265	0.001271
S	677	Q677H	caG	caT	109	118	B.1.470	0.15309
S	677	Q677H	caG	caC	9	118	B.1.470	0.01264
S	677	Q677H	caG	caT	107	107	B.1.1.50	0.072641
S	677	Q677H	caG	caT	78	106	C.37	0.009053
S	677	Q677H	caG	caC	28	106	C.37	0.00325
S	677	Q677H	caG	caT	98	99	AY.61	0.010268
S	677	Q677H	caG	caC	1	99	AY.61	0.000105
S	677	Q677R	cAg	cGg	97	99	B.1.2	0.000854
S	677	Q677R	cAG	cGC	1	99	B.1.2	0.000009
S	677	Q677R	cAG	cGA	1	99	B.1.2	0.000009
S	677	Q677R	cAg	cGg	98	98	B.1.429	0.002306
S	677	Q677H	caG	caT	61	95	B.1.429	0.001435
S	677	Q677H	caG	caC	34	95	B.1.429	0.0008
S	677	Q677K	Cag	Aag	93	93	B.1.1	0.001687
S	677	Q677H	caG	caT	79	93	B.1.1.222	0.016116
S	677	Q677H	caG	caC	14	93	B.1.1.222	0.002856
S	677	Q677H	caG	caT	85	93	B.1.1.306	0.037264
S	677	Q677H	caG	caC	8	93	B.1.1.306	0.003507
S	677	Q677H	caG	caT	84	86	B.1.258	0.00559
S	677	Q677H	caG	caC	2	86	B.1.258	0.000133
S	677	Q677H	caG	caT	84	84	AA.1	0.608696
S	677	Q677H	caG	caC	49	83	AY.33	0.003272
S	677	Q677H	caG	caT	34	83	AY.33	0.00227
S	677	Q677H	caG	caT	57	73	B.1.1.519	0.002264
S	677	Q677H	caG	caC	16	73	B.1.1.519	0.000635
S	677	Q677H	caG	caT	72	72	B.1.36.18	0.030252
S	677	Q677R	cAg	cGg	70	70	B.1.351	0.002081
S	677	Q677P	cAg	cCg	69	69	B.1	0.000632
S	677	Q677H	caG	caC	69	69	R.2	1
S	677	Q677H	caG	caC	59	66	AY.106	0.019759
S	677	Q677H	caG	caT	7	66	AY.106	0.002344
S	677	Q677H	caG	caT	38	66	B.1.243	0.002644
S	677	Q677H	caG	caC	28	66	B.1.243	0.001948
S	677	Q677H	caG	caT	61	65	AY.4.2	0.001323
S	677	Q677H	caG	caC	4	65	AY.4.2	0.000087
S	677	Q677H	caG	caC	42	64	P.1.14	0.002008
S	677	Q677H	caG	caT	22	64	P.1.14	0.001052
S	677	Q677H	caG	caC	42	61	AY.46	0.004371
S	677	Q677H	caG	caT	19	61	AY.46	0.001978
S	677	Q677H	caG	caC	58	58	B.1.429.1	0.698795
S	677	Q677H	caG	caC	36	55	B.1.1.214	0.001996
S	677	Q677H	caG	caT	19	55	B.1.1.214	0.001054
S	677	Q677R	cAg	cGg	51	51	B.1.243	0.003549
S	677	Q677P	cAg	cCg	49	49	B.1.617.2	0.000185
S	677	Q677H	caG	caT	37	43	AY.75	0.002073
S	677	Q677H	caG	caC	6	43	AY.75	0.000336
S	677	Q677H	caG	caT	42	43	B.1.189	0.180258
S	677	Q677H	caG	caC	1	43	B.1.189	0.004292
S	677	Q677K	Cag	Aag	42	42	B.1	0.000385
S	677	Q677H	caG	caC	26	42	B.1.36.29	0.013451
S	677	Q677H	caG	caT	16	42	B.1.36.29	0.008277
S	677	Q677H	caG	caC	24	36	AY.119	0.000847
S	677	Q677H	caG	caT	12	36	AY.119	0.000424
S	677	Q677H	caG	caC	19	36	AY.6	0.000781
S	677	Q677H	caG	caT	17	36	AY.6	0.000699
S	677	Q677H	caG	caT	25	36	AY.9.2	0.000918
S	677	Q677H	caG	caC	11	36	AY.9.2	0.000404
S	677	Q677H	caG	caT	21	35	AY.23	0.001465
S	677	Q677H	caG	caC	14	35	AY.23	0.000976
S	677	Q677H	caG	caT	34	35	B.1.1.28	0.010582
S	677	Q677H	caG	caC	1	35	B.1.1.28	0.000311
S	677	Q677H	caG	caT	28	35	B.1.36.8	0.028
S	677	Q677H	caG	caC	7	35	B.1.36.8	0.007
S	677	Q677H	caG	caT	31	34	AY.26	0.000878
S	677	Q677H	caG	caC	3	34	AY.26	0.000085
S	677	Q677del	CAG	---	34	34	B.1	0.000311
S	677	Q677H	caG	caT	33	34	B.1.1.63	0.012731
S	677	Q677H	caG	caC	1	34	B.1.1.63	0.000386
S	677	Q677H	caG	caT	23	33	AY.99.2	0.00212
S	677	Q677H	caG	caC	10	33	AY.99.2	0.000922
S	677	Q677H	caG	caT	27	32	AY.113	0.003845
S	677	Q677H	caG	caC	5	32	AY.113	0.000712
S	677	Q677H	caG	caT	25	32	B	0.003195
S	677	Q677H	caG	caC	7	32	B	0.000895
S	677	Q677H	caG	caT	26	31	AY.42	0.001046
S	677	Q677H	caG	caC	5	31	AY.42	0.000201
S	677	Q677R	cAg	cGg	30	31	B.1	0.000275
S	677	Q677R	cAG	cGA	1	31	B.1	0.000009
S	677	Q677H	caG	caT	26	29	AY.29	0.00041
S	677	Q677H	caG	caC	3	29	AY.29	0.000047
S	677	Q677H	caG	caT	29	29	B.1.618	0.116935
S	677	Q677H	caG	caT	29	29	C.36.2	1
S	677	Q677H	caG	caC	22	28	AY.117	0.001859
S	677	Q677H	caG	caT	6	28	AY.117	0.000507
S	677	Q677H	caG	caC	28	28	AY.46.1	0.028747
S	677	Q677H	caG	caT	27	27	AY.39.1	0.00107
S	677	Q677H	caG	caC	17	27	B.1.1.216	0.015138
S	677	Q677H	caG	caT	10	27	B.1.1.216	0.008905
S	677	Q677H	caG	caT	27	27	Q.7	0.03
S	677	Q677H	caG	caC	21	26	AY.36	0.003112
S	677	Q677H	caG	caT	5	26	AY.36	0.000741
S	677	Q677H	caG	caC	24	26	B.1.36.31	0.042032
S	677	Q677H	caG	caT	2	26	B.1.36.31	0.003503
S	677	Q677H	caG	caT	23	26	R.1	0.00207
S	677	Q677H	caG	caC	3	26	R.1	0.00027
S	677	Q677R	cAg	cGg	25	25	B.1.1.311	0.008954
S	677	Q677H	caG	caT	22	25	B.1.637	0.001608
S	677	Q677H	caG	caC	3	25	B.1.637	0.000219
S	677	Q677H	caG	caC	18	24	B.1.236	0.036961
S	677	Q677H	caG	caT	6	24	B.1.236	0.01232
S	677	Q677H	caG	caT	23	24	B.1.36.22	0.027778
S	677	Q677H	caG	caC	1	24	B.1.36.22	0.001208
S	677	Q677H	caG	caC	24	24	B.1.378	0.164384
S	677	Q677X	Cag	Tag	22	23	All	0.000004
S	677	Q677X	CaG	TaA	1	23	All	0
S	677	Q677P	cAg	cCg	23	23	AY.4	0.000036
S	677	Q677P	cAg	cCg	22	22	AY.102	0.000583
S	677	Q677H	caG	caT	14	22	B.1.621	0.001239
S	677	Q677H	caG	caC	8	22	B.1.621	0.000708
S	677	Q677H	caG	caT	16	22	P.2	0.002986
S	677	Q677H	caG	caC	6	22	P.2	0.00112
S	677	Q677H	caG	caT	20	21	B.1.221	0.001421
S	677	Q677H	caG	caC	1	21	B.1.221	0.000071
S	677	Q677H	caG	caT	21	21	B.1.232	0.011284
S	677	Q677H	caG	caT	16	21	P.1.15	0.003717
S	677	Q677H	caG	caC	5	21	P.1.15	0.001162
S	677	Q677Y	CaG	TaC	10	20	All	0.000002
S	677	Q677Y	CaG	TaT	10	20	All	0.000002
S	677	Q677H	caG	caT	19	20	AY.20	0.000738
S	677	Q677H	caG	caC	1	20	AY.20	0.000039
S	677	Q677R	cAg	cGg	20	20	B.1.1.306	0.008768
S	677	Q677H	caG	caT	18	20	B.1.456	0.058824
S	677	Q677H	caG	caC	2	20	B.1.456	0.006536
S	677	Q677Q	caG	caA	19	19	B.1.623	0.010193
S	677	Q677H	caG	caT	11	18	AY.5	0.000227
S	677	Q677H	caG	caC	7	18	AY.5	0.000145
S	677	Q677H	caG	caT	17	18	B.1.1.33	0.007155
S	677	Q677H	caG	caC	1	18	B.1.1.33	0.000421
S	677	Q677R	cAg	cGg	18	18	P.1	0.000284
S	677	Q677H	caG	caT	18	18	P.1.17	0.002912
S	677	Q677H	caG	caC	9	17	AY.120	0.000335
S	677	Q677H	caG	caT	8	17	AY.120	0.000297
S	677	Q677H	caG	caT	11	17	AY.45	0.001339
S	677	Q677H	caG	caC	6	17	AY.45	0.00073
S	677	Q677H	caG	caT	17	17	B.1.1.25	0.009665
S	677	Q677H	caG	caC	17	17	B.1.1.318	0.00513
S	677	Q677H	caG	caT	17	17	B.1.582	0.008342
S	677	Q677H	caG	caT	15	17	B.1.617.1	0.001934
S	677	Q677H	caG	caC	2	17	B.1.617.1	0.000258
S	677	Q677R	cAg	cGg	17	17	B.1.617.2	0.000064
S	677	Q677H	caG	caT	17	17	P.3	0.027113
S	677	Q677R	cAG	cGC	16	16	AY.34	0.001551
S	677	Q677L	cAg	cTg	16	16	AY.4	0.000025
S	677	Q677del	CAG	---	16	16	AY.44	0.000097
S	677	Q677R	cAg	cGg	16	16	AY.99	0.016789
S	677	Q677H	caG	caT	16	16	B.1.1.1	0.005227
S	677	Q677H	caG	caC	14	16	B.1.111	0.016451
S	677	Q677H	caG	caT	2	16	B.1.111	0.00235
S	677	Q677R	cAg	cGg	16	16	B.1.36	0.002334
S	677	Q677H	caG	caT	15	15	B.1.596.1	0.140187
S	677	Q677H	caG	caT	15	15	C.17	0.833333
S	677	Q677H	caG	caT	13	14	A.1	0.003664
S	677	Q677H	caG	caC	1	14	A.1	0.000282
S	677	Q677R	cAg	cGg	14	14	AY.4	0.000022
S	677	Q677H	caG	caT	13	14	AY.58	0.011797
S	677	Q677H	caG	caC	1	14	AY.58	0.000907
S	677	Q677del	CAG	---	14	14	B.1.1	0.000254
S	677	Q677H	caG	caT	11	14	B.1.1.294	0.013924
S	677	Q677H	caG	caC	3	14	B.1.1.294	0.003797
S	677	Q677H	caG	caC	13	14	B.1.1.512	0.371429
S	677	Q677H	caG	caT	1	14	B.1.1.512	0.028571
S	677	Q677R	cAg	cGg	12	13	AY.25	0.000072
S	677	Q677R	cAG	cGC	1	13	AY.25	0.000006
S	677	Q677H	caG	caT	13	13	AY.4.5	0.001397
S	677	Q677H	caG	caT	13	13	AY.9	0.000879
S	677	Q677Q	caG	caA	13	13	B.1.2	0.000114
S	677	Q677H	caG	caT	12	13	B.1.214.1	0.24
S	677	Q677H	caG	caC	1	13	B.1.214.1	0.02
S	677	Q677H	caG	caT	13	13	B.1.425	0.038922
S	677	Q677H	caG	caT	13	13	L.3	0.046099
S	677	Q677H	caG	caT	12	12	AY.100	0.000552
S	677	Q677H	caG	caT	12	12	AY.54	0.001144
S	677	Q677H	caG	caT	8	12	AY.75.1	0.001442
S	677	Q677H	caG	caC	4	12	AY.75.1	0.000721
S	677	Q677R	cAg	cGg	12	12	B.1.1.216	0.010686
S	677	Q677H	caG	caC	9	12	B.1.1.277	0.006829
S	677	Q677H	caG	caT	3	12	B.1.1.277	0.002276
S	677	Q677H	caG	caT	12	12	B.1.258.14	0.011765
S	677	Q677H	caG	caT	12	12	B.1.351.5	0.007194
S	677	Q677H	caG	caT	12	12	B.1.36.10	0.057416
S	677	Q677Q	caG	caA	12	12	B.1.602	0.078431
S	677	Q677H	caG	caT	9	11	AY.47	0.00028
S	677	Q677H	caG	caC	2	11	AY.47	0.000062
S	677	Q677H	caG	caC	8	11	AY.84	0.0035
S	677	Q677H	caG	caT	3	11	AY.84	0.001312
S	677	Q677R	cAg	cGg	11	11	B.1.1	0.0002
S	677	Q677H	caG	caT	11	11	B.1.1.10	0.012263
S	677	Q677H	caG	caT	11	11	B.1.1.271	0.611111
S	677	Q677H	caG	caT	11	11	B.1.177.33	0.018092
S	677	Q677H	caG	caT	7	11	B.1.177.35	0.004838
S	677	Q677H	caG	caC	4	11	B.1.177.35	0.002764
S	677	Q677H	caG	caT	10	11	B.1.177.73	0.005663
S	677	Q677H	caG	caC	1	11	B.1.177.73	0.000566
S	677	Q677R	cAg	cGg	11	11	B.1.236	0.022587
S	677	Q677R	cAg	cGg	11	11	B.1.639	0.23913
S	677	Q677H	caG	caT	7	10	AY.121	0.000947
S	677	Q677H	caG	caC	3	10	AY.121	0.000406
S	677	Q677P	cAg	cCg	10	10	AY.25	0.00006
S	677	Q677P	cAg	cCg	10	10	B.1.1	0.000181
S	677	Q677H	caG	caC	10	10	B.1.1.239	0.322581
S	677	Q677del	CAG	---	10	10	B.1.160	0.000312
S	677	Q677H	caG	caT	10	10	B.1.36.16	0.014245
S	677	Q677H	caG	caT	8	10	B.1.577	0.005498
S	677	Q677H	caG	caC	2	10	B.1.577	0.001375
S	677	Q677H	caG	caT	7	10	B.1.609	0.003356
S	677	Q677H	caG	caC	3	10	B.1.609	0.001438
S	677	Q677H	caG	caT	9	9	AY.27	0.000582
S	677	Q677H	caG	caT	7	9	AY.55	0.006422
S	677	Q677H	caG	caC	2	9	AY.55	0.001835
S	677	Q677H	caG	caT	6	9	AY.99	0.006296
S	677	Q677H	caG	caC	3	9	AY.99	0.003148
S	677	Q677H	caG	caT	9	9	B.1.1.372	0.006198
S	677	Q677Y	CaG	TaC	5	9	B.1.1.7	0.000004
S	677	Q677Y	CaG	TaT	4	9	B.1.1.7	0.000004
S	677	Q677H	caG	caT	8	9	B.1.170	0.034483
S	677	Q677H	caG	caC	1	9	B.1.170	0.00431
S	677	Q677H	caG	caC	7	9	B.1.177.21	0.000535
S	677	Q677H	caG	caT	2	9	B.1.177.21	0.000153
S	677	Q677Q	caG	caA	9	9	B.1.243	0.000626
S	677	Q677H	caG	caC	8	9	B.1.351.2	0.002421
S	677	Q677H	caG	caT	1	9	B.1.351.2	0.000303
S	677	Q677H	caG	caC	9	9	B.1.564	0.003833
S	677	Q677H	caG	caT	9	9	Q.1	0.001137
S	677	Q677H	caG	caT	8	8	AY.101	0.003923
S	677	Q677H	caG	caC	7	8	AY.116	0.002007
S	677	Q677H	caG	caT	1	8	AY.116	0.000287
S	677	Q677H	caG	caT	8	8	AY.118	0.000501
S	677	Q677H	caG	caT	8	8	AY.16.1	0.003759
S	677	Q677R	cAg	cGg	8	8	AY.3	0.00008
S	677	Q677del	CAG	---	8	8	AY.43	0.000035
S	677	Q677Q	caG	caA	8	8	AY.44	0.000049
S	677	Q677H	caG	caC	8	8	AY.46.2	0.005083
S	677	Q677H	caG	caC	6	8	AY.5.3	0.002024
S	677	Q677H	caG	caT	2	8	AY.5.3	0.000675
S	677	Q677H	caG	caC	5	8	AY.5.4	0.001384
S	677	Q677H	caG	caT	3	8	AY.5.4	0.00083
S	677	Q677H	caG	caC	4	8	AY.68	0.001095
S	677	Q677H	caG	caT	4	8	AY.68	0.001095
S	677	Q677H	caG	caT	8	8	AY.74	0.000925
S	677	Q677H	caG	caT	6	8	AY.98	0.000474
S	677	Q677H	caG	caC	2	8	AY.98	0.000158
S	677	Q677H	caG	caT	8	8	B.1.1.135	0.037559
S	677	Q677H	caG	caC	8	8	B.1.1.261	0.068966
S	677	Q677del	CAG	---	8	8	B.1.1.7	0.000007
S	677	Q677H	caG	caT	8	8	B.1.160.32	0.034335
S	677	Q677H	caG	caC	7	8	B.1.400	0.003003
S	677	Q677H	caG	caT	1	8	B.1.400	0.000429
S	677	Q677H	caG	caT	8	8	B.1.401	0.065574
S	677	Q677H	caG	caT	4	8	B.1.416	0.005076
S	677	Q677H	caG	caC	4	8	B.1.416	0.005076
S	677	Q677H	caG	caC	7	8	B.1.438.1	0.000751
S	677	Q677H	caG	caT	1	8	B.1.438.1	0.000107
S	677	Q677H	caG	caT	7	8	B.1.466.2	0.002739
S	677	Q677H	caG	caC	1	8	B.1.466.2	0.000391
S	677	Q677H	caG	caT	8	8	B.1.588	0.007279
S	677	Q677Q	caG	caA	8	8	B.1.617.2	0.00003
S	677	Q677H	caG	caT	5	8	C.16	0.005302
S	677	Q677H	caG	caC	3	8	C.16	0.003181
S	677	Q677H	caG	caT	6	7	A	0.002322
S	677	Q677H	caG	caC	1	7	A	0.000387
S	677	Q677H	caG	caT	7	7	AD.2	0.001533
S	677	Q677E	Cag	Gag	7	7	All	0.000001
S	677	Q677H	caG	caT	6	7	AY.120.1	0.001926
S	677	Q677H	caG	caC	1	7	AY.120.1	0.000321
S	677	Q677L	cAg	cTg	7	7	AY.14	0.000616
S	677	Q677R	cAg	cGg	7	7	AY.35	0.001631
S	677	Q677H	caG	caC	5	7	AY.92	0.001436
S	677	Q677H	caG	caT	2	7	AY.92	0.000575
S	677	Q677X	Cag	Tag	7	7	B.1	0.000064
S	677	Q677H	caG	caT	4	7	B.1.1.326	0.007042
S	677	Q677H	caG	caC	3	7	B.1.1.326	0.005282
S	677	Q677K	Cag	Aag	7	7	B.1.1.7	0.000006
S	677	Q677H	caG	caT	7	7	B.1.126	0.008929
S	677	Q677H	caG	caT	7	7	B.1.177.53	0.016746
S	677	Q677H	caG	caT	7	7	B.1.177.75	0.007284
S	677	Q677H	caG	caT	7	7	B.1.240	0.001509
S	677	Q677H	caG	caT	6	7	B.1.346	0.007864
S	677	Q677H	caG	caC	1	7	B.1.346	0.001311
S	677	Q677H	caG	caT	7	7	B.1.350.1	1
S	677	Q677H	caG	caT	7	7	B.1.351.3	0.006135
S	677	Q677H	caG	caT	6	7	B.1.369	0.001711
S	677	Q677H	caG	caC	1	7	B.1.369	0.000285
S	677	Q677del	CAG	---	7	7	B.1.617.2	0.000026
S	677	Q677H	caG	caT	7	7	B.1.620	0.006623
S	677	Q677H	caG	caT	7	7	B.1.93	0.006536
S	677	Q677K	Cag	Aag	7	7	P.1	0.00011
S	677	Q677Q	caG	caA	7	7	P.1	0.00011
S	677	Q677Q	caG	caA	6	6	AY.25	0.000036
S	677	Q677del	CAG	---	6	6	AY.4	0.000009
S	677	Q677H	caG	caC	5	6	AY.62	0.002179
S	677	Q677H	caG	caT	1	6	AY.62	0.000436
S	677	Q677Q	caG	caA	6	6	AY.70	0.001251
S	677	Q677H	caG	caT	6	6	B.1.1.282	0.069767
S	677	Q677H	caG	caT	4	6	B.1.1.416	0.00362
S	677	Q677H	caG	caC	2	6	B.1.1.416	0.00181
S	677	Q677P	cAg	cCg	6	6	B.1.1.7	0.000005
S	677	Q677R	cAg	cGg	6	6	B.1.177.43	0.008863
S	677	Q677H	caG	caT	6	6	B.1.177.7	0.000989
S	677	Q677Q	caG	caA	6	6	B.1.177.83	0.008889
S	677	Q677H	caG	caT	5	6	B.1.311	0.001373
S	677	Q677H	caG	caC	1	6	B.1.311	0.000275
S	677	Q677H	caG	caC	5	6	B.1.396	0.003529
S	677	Q677H	caG	caT	1	6	B.1.396	0.000706
S	677	Q677H	caG	caT	4	6	B.1.576	0.003626
S	677	Q677H	caG	caC	2	6	B.1.576	0.001813
S	677	Q677H	caG	caT	6	6	B.1.595	0.001566
S	677	Q677H	caG	caT	6	6	C.39	0.113208
S	677	Q677H	caG	caT	5	5	A.2.5	0.002495
S	677	Q677R	cAg	cGg	5	5	AE.8	0.002445
S	677	Q677del	CAG	---	5	5	AY.107	0.00233
S	677	Q677H	caG	caT	3	5	AY.16	0.001139
S	677	Q677H	caG	caC	2	5	AY.16	0.000759
S	677	Q677H	caG	caT	5	5	AY.67	0.002321
S	677	Q677H	caG	caT	5	5	AY.69	0.000933
S	677	Q677H	caG	caC	5	5	AY.81	0.00996
S	677	Q677H	caG	caT	5	5	B.1.1.159	0.023364
S	677	Q677H	caG	caT	5	5	B.1.1.263	0.007788
S	677	Q677H	caG	caT	4	5	B.1.1.37	0.000771
S	677	Q677H	caG	caC	1	5	B.1.1.37	0.000193
S	677	Q677H	caG	caT	5	5	B.1.1.434	0.001743
S	677	Q677Q	caG	caA	5	5	B.1.1.519	0.000199
S	677	Q677H	caG	caT	5	5	B.1.1.521	0.026738
S	677	Q677H	caG	caT	5	5	B.1.177.23	0.016181
S	677	Q677H	caG	caT	5	5	B.1.177.44	0.002595
S	677	Q677H	caG	caT	5	5	B.1.177.86	0.000917
S	677	Q677H	caG	caT	4	5	B.1.258.3	0.0067
S	677	Q677H	caG	caC	1	5	B.1.258.3	0.001675
S	677	Q677H	caG	caT	4	5	B.1.367	0.00317
S	677	Q677H	caG	caC	1	5	B.1.367	0.000792
S	677	Q677Q	caG	caA	5	5	B.1.429	0.000118
S	677	Q677H	caG	caC	4	5	B.1.437	0.083333
S	677	Q677H	caG	caT	1	5	B.1.437	0.020833
S	677	Q677H	caG	caT	5	5	B.1.459	0.020408
S	677	Q677H	caG	caT	5	5	B.1.468	0.028571
S	677	Q677H	caG	caT	4	5	B.1.560	0.018519
S	677	Q677H	caG	caC	1	5	B.1.560	0.00463
S	677	Q677H	caG	caT	5	5	B.1.580	0.020325
S	677	Q677H	caG	caT	4	5	B.1.587	0.00759
S	677	Q677H	caG	caC	1	5	B.1.587	0.001898
S	677	Q677H	caG	caT	5	5	B.6	0.00455
S	677	Q677H	caG	caT	5	5	D.2	0.000375
S	677	Q677H	caG	caT	5	5	N.5	0.008834
S	677	Q677H	caG	caT	5	5	P.1.7	0.001596
S	677	Q677H	caG	caC	3	4	AY.104	0.005952
S	677	Q677H	caG	caT	1	4	AY.104	0.001984
S	677	Q677H	caG	caT	3	4	AY.12	0.000948
S	677	Q677H	caG	caC	1	4	AY.12	0.000316
S	677	Q677H	caG	caT	3	4	AY.14	0.000264
S	677	Q677H	caG	caC	1	4	AY.14	0.000088
S	677	Q677H	caG	caC	4	4	AY.22	0.008368
S	677	Q677H	caG	caT	4	4	AY.3.1	0.000341
S	677	Q677H	caG	caT	4	4	AY.35	0.000932
S	677	Q677H	caG	caT	3	4	AY.46.6	0.000217
S	677	Q677H	caG	caC	1	4	AY.46.6	0.000072
S	677	Q677H	caG	caT	4	4	AY.71	0.0019
S	677	Q677del	CAG	---	4	4	B	0.000511
S	677	Q677Q	caG	caA	4	4	B.1	0.000037
S	677	Q677X	Cag	Tag	3	4	B.1.1	0.000054
S	677	Q677X	CaG	TaA	1	4	B.1.1	0.000018
S	677	Q677H	caG	caT	4	4	B.1.1.192	0.009238
S	677	Q677H	caG	caT	4	4	B.1.1.255	0.012121
S	677	Q677H	caG	caC	2	4	B.1.1.305	0.007722
S	677	Q677H	caG	caT	2	4	B.1.1.305	0.007722
S	677	Q677H	caG	caT	4	4	B.1.1.315	0.033898
S	677	Q677H	caG	caT	4	4	B.1.1.317	0.001647
S	677	Q677H	caG	caT	4	4	B.1.1.325	0.102564
S	677	Q677H	caG	caT	3	4	B.1.1.340	0.136364
S	677	Q677H	caG	caC	1	4	B.1.1.340	0.045455
S	677	Q677H	caG	caT	4	4	B.1.1.348	0.003185
S	677	Q677H	caG	caT	4	4	B.1.1.354	0.017544
S	677	Q677H	caG	caT	3	4	B.1.1.39	0.001529
S	677	Q677H	caG	caC	1	4	B.1.1.39	0.00051
S	677	Q677H	caG	caT	4	4	B.1.1.41	0.025316
S	677	Q677H	caG	caT	4	4	B.1.1.57	0.045977
S	677	Q677H	caG	caT	4	4	B.1.177.81	0.000757
S	677	Q677H	caG	caT	3	4	B.1.258.17	0.000312
S	677	Q677H	caG	caC	1	4	B.1.258.17	0.000104
S	677	Q677R	cAg	cGg	4	4	B.1.356	0.006908
S	677	Q677H	caG	caT	4	4	B.1.36.35	0.010417
S	677	Q677R	cAg	cGg	4	4	B.1.470	0.005618
S	677	Q677H	caG	caT	4	4	B.1.538	0.032258
S	677	Q677H	caG	caT	4	4	B.1.561	0.001588
S	677	Q677H	caG	caT	3	4	B.1.625	0.007059
S	677	Q677H	caG	caC	1	4	B.1.625	0.002353
S	677	Q677H	caG	caT	2	4	B.40	0.000729
S	677	Q677H	caG	caC	2	4	B.40	0.000729
S	677	Q677R	cAg	cGg	4	4	C.14	0.017316
S	677	Q677H	caG	caT	3	4	C.23	0.017442
S	677	Q677H	caG	caC	1	4	C.23	0.005814
S	677	Q677P	cAg	cCg	4	4	P.1	0.000063
S	677	Q677H	caG	caC	4	4	P.1.1	0.001271
S	677	Q677del	CAG	---	4	4	P.1.15	0.000929
S	677	Q677H	caG	caT	4	4	P.1.2	0.004624
S	677	Q677H	caG	caC	4	4	Q.8	0.00066
S	677	Q677del1	Cag	-ag	2	3	All	0
S	677	Q677del1	cAg	c-g	1	3	All	0
S	677	Q677P	cAg	cCg	3	3	AY.103	0.000019
S	677	Q677del	CAG	---	3	3	AY.103	0.000019
S	677	Q677H	caG	caT	3	3	AY.108	0.003308
S	677	Q677H	caG	caC	3	3	AY.21	0.005693
S	677	Q677del	CAG	---	3	3	AY.25	0.000018
S	677	Q677L	cAg	cTg	3	3	AY.26	0.000085
S	677	Q677H	caG	caT	2	3	AY.32	0.001065
S	677	Q677H	caG	caC	1	3	AY.32	0.000532
S	677	Q677L	cAg	cTg	3	3	AY.39	0.000074
S	677	Q677P	cAg	cCg	3	3	AY.39	0.000074
S	677	Q677R	cAg	cGg	3	3	AY.44	0.000018
S	677	Q677H	caG	caT	2	3	AY.53	0.000575
S	677	Q677H	caG	caC	1	3	AY.53	0.000288
S	677	Q677L	cAg	cTg	3	3	AY.57	0.001969
S	677	Q677H	caG	caT	3	3	AY.7.1	0.000338
S	677	Q677H	caG	caT	3	3	AY.8	0.001818
S	677	Q677H	caG	caT	2	3	AY.91	0.001461
S	677	Q677H	caG	caC	1	3	AY.91	0.00073
S	677	Q677del	CAG	---	3	3	AY.93	0.000819
S	677	Q677L	cAg	cTg	3	3	B.1.1.1	0.00098
S	677	Q677H	caG	caT	3	3	B.1.1.133	0.025424
S	677	Q677H	caG	caT	2	3	B.1.1.170	0.002494
S	677	Q677H	caG	caC	1	3	B.1.1.170	0.001247
S	677	Q677H	caG	caT	3	3	B.1.1.243	0.012245
S	677	Q677H	caG	caT	3	3	B.1.1.253	0.007519
S	677	Q677H	caG	caT	3	3	B.1.1.312	0.005736
S	677	Q677H	caG	caC	3	3	B.1.1.51	0.005155
S	677	Q677R	cAg	cGg	3	3	B.1.1.63	0.001157
S	677	Q677E	Cag	Gag	3	3	B.1.1.7	0.000003
S	677	Q677H	caG	caT	3	3	B.1.131	0.026316
S	677	Q677H	caG	caT	3	3	B.1.177.12	0.000455
S	677	Q677H	caG	caT	3	3	B.1.177.60	0.000655
S	677	Q677Y	CaG	TaC	2	3	B.1.2	0.000018
S	677	Q677Y	CaG	TaT	1	3	B.1.2	0.000009
S	677	Q677H	caG	caT	3	3	B.1.210	0.006397
S	677	Q677H	caG	caC	3	3	B.1.221.4	0.0125
S	677	Q677H	caG	caT	3	3	B.1.237	0.014925
S	677	Q677H	caG	caT	3	3	B.1.258.4	0.010345
S	677	Q677R	cAg	cGg	3	3	B.1.264.1	0.142857
S	677	Q677H	caG	caC	2	3	B.1.336	0.004878
S	677	Q677H	caG	caT	1	3	B.1.336	0.002439
S	677	Q677R	cAg	cGg	3	3	B.1.36.10	0.014354
S	677	Q677H	caG	caT	3	3	B.1.36.17	0.001482
S	677	Q677H	caG	caT	3	3	B.1.36.24	0.018519
S	677	Q677H	caG	caT	3	3	B.1.480	0.007463
S	677	Q677H	caG	caT	2	3	B.1.499	0.002101
S	677	Q677H	caG	caC	1	3	B.1.499	0.00105
S	677	Q677H	caG	caT	3	3	B.1.540	0.029126
S	677	Q677H	caG	caC	3	3	B.1.605	0.017857
S	677	Q677H	caG	caT	3	3	B.1.628	0.001057
S	677	Q677H	caG	caT	3	3	B.3	0.002492
S	677	Q677H	caG	caT	3	3	C.14	0.012987
S	677	Q677H	caG	caT	3	3	N.6	0.021277
S	677	Q677del	CAG	---	3	3	P.1	0.000047
S	677	Q677H	caG	caT	2	3	P.1.12	0.000968
S	677	Q677H	caG	caC	1	3	P.1.12	0.000484
S	677	Q677H	caG	caT	2	3	Q.3	0.00029
S	677	Q677H	caG	caC	1	3	Q.3	0.000145
S	677	Q677K	Cag	Aag	2	2		0.111111
S	677	Q677L	cAG	cTA	2	2		0.111111
S	677	Q677del	CAG	---	2	2	A	0.000774
S	677	Q677H	caG	caT	2	2	A.2	0.001324
S	677	Q677H	caG	caT	2	2	A.2.2	0.003378
S	677	Q677H	caG	caT	1	2	A.25	0.018182
S	677	Q677H	caG	caC	1	2	A.25	0.018182
S	677	Q677H	caG	caC	2	2	A.28	0.005291
S	677	Q677H	caG	caC	2	2	AU.1	0.002532
S	677	Q677H	caG	caT	2	2	AY.1	0.000791
S	677	Q677H	caG	caC	1	2	AY.110	0.000113
S	677	Q677H	caG	caT	1	2	AY.110	0.000113
S	677	Q677L	cAg	cTg	2	2	AY.119	0.000071
S	677	Q677H	caG	caT	2	2	AY.13	0.000322
S	677	Q677H	caG	caT	2	2	AY.15	0.004444
S	677	Q677R	cAg	cGg	2	2	AY.20	0.000078
S	677	Q677Q	caG	caA	2	2	AY.3	0.00002
S	677	Q677L	cAg	cTg	2	2	AY.33	0.000134
S	677	Q677del	CAG	---	2	2	AY.34	0.000194
S	677	Q677P	cAg	cCg	2	2	AY.34.1	0.00102
S	677	Q677R	cAg	cGg	2	2	AY.39	0.000049
S	677	Q677H	caG	caT	2	2	AY.40	0.001929
S	677	Q677R	cAg	cGg	2	2	AY.43	0.000009
S	677	Q677P	cAg	cCg	2	2	AY.46	0.000208
S	677	Q677H	caG	caT	2	2	AY.46.3	0.001867
S	677	Q677H	caG	caT	2	2	AY.46.4	0.000329
S	677	Q677H	caG	caT	2	2	AY.46.5	0.000397
S	677	Q677L	cAg	cTg	2	2	AY.47	0.000062
S	677	Q677H	caG	caT	1	2	AY.59	0.00053
S	677	Q677H	caG	caC	1	2	AY.59	0.00053
S	677	Q677H	caG	caT	2	2	AY.63	0.000774
S	677	Q677H	caG	caT	2	2	AY.7	0.000392
S	677	Q677H	caG	caT	2	2	AY.70	0.000417
S	677	Q677H	caG	caT	2	2	AY.77	0.002255
S	677	Q677H	caG	caT	2	2	AY.82	0.002714
S	677	Q677H	caG	caC	1	2	AY.85	0.000427
S	677	Q677H	caG	caT	1	2	AY.85	0.000427
S	677	Q677P	cAg	cCg	2	2	AY.86	0.00166
S	677	Q677Q	caG	caA	2	2	AY.9.1	0.000167
S	677	Q677L	cAg	cTg	2	2	AY.98	0.000158
S	677	Q677R	cAg	cGg	2	2	AY.99.1	0.003106
S	677	Q677H	caG	caT	2	2	B.1.1.128	0.014184
S	677	Q677K	Cag	Aag	2	2	B.1.1.145	0.074074
S	677	Q677H	caG	caT	2	2	B.1.1.201	0.04878
S	677	Q677H	caG	caT	2	2	B.1.1.219	0.01
S	677	Q677H	caG	caT	2	2	B.1.1.232	0.00363
S	677	Q677H	caG	caT	2	2	B.1.1.241	0.004141
S	677	Q677R	cAg	cGg	2	2	B.1.1.28	0.000622
S	677	Q677K	Cag	Aag	2	2	B.1.1.294	0.002532
S	677	Q677H	caG	caT	2	2	B.1.1.329	0.007692
S	677	Q677H	caG	caT	2	2	B.1.1.344	0.021505
S	677	Q677H	caG	caT	2	2	B.1.1.375	0.02381
S	677	Q677H	caG	caT	2	2	B.1.1.377	0.002762
S	677	Q677H	caG	caT	2	2	B.1.1.389	0.012121
S	677	Q677H	caG	caT	2	2	B.1.1.407	0.083333
S	677	Q677H	caG	caT	2	2	B.1.1.412	0.015267
S	677	Q677H	caG	caT	2	2	B.1.1.413	0.013793
S	677	Q677L	cAg	cTg	2	2	B.1.1.434	0.000697
S	677	Q677H	caG	caC	2	2	B.1.1.44	0.004819
S	677	Q677H	caG	caT	2	2	B.1.1.448	0.004065
S	677	Q677H	caG	caT	1	2	B.1.1.464	0.001473
S	677	Q677H	caG	caC	1	2	B.1.1.464	0.001473
S	677	Q677H	caG	caC	2	2	B.1.1.467	0.038462
S	677	Q677H	caG	caC	2	2	B.1.1.526	0.007092
S	677	Q677H	caG	caT	2	2	B.1.1.56	0.035714
S	677	Q677X	Cag	Tag	2	2	B.1.1.7	0.000002
S	677	Q677H	caG	caT	2	2	B.1.118	0.013423
S	677	Q677L	cAg	cTg	2	2	B.1.177	0.000026
S	677	Q677del	CAG	---	2	2	B.1.177	0.000026
S	677	Q677H	caG	caT	2	2	B.1.177.31	0.022989
S	677	Q677H	caG	caT	2	2	B.1.177.47	0.025974
S	677	Q677H	caG	caT	1	2	B.1.177.56	0.000668
S	677	Q677H	caG	caC	1	2	B.1.177.56	0.000668
S	677	Q677H	caG	caT	2	2	B.1.177.6	0.001953
S	677	Q677H	caG	caT	2	2	B.1.214.2	0.001199
S	677	Q677H	caG	caT	2	2	B.1.258.16	0.003273
S	677	Q677K	Cag	Aag	2	2	B.1.351	0.000059
S	677	Q677H	caG	caT	2	2	B.1.36.1	0.002281
S	677	Q677H	caG	caT	2	2	B.1.36.19	0.018519
S	677	Q677H	caG	caT	2	2	B.1.36.34	0.042553
S	677	Q677P	cAg	cCg	2	2	B.1.369	0.00057
S	677	Q677H	caG	caT	1	2	B.1.375	0.00082
S	677	Q677H	caG	caC	1	2	B.1.375	0.00082
S	677	Q677del	CAG	---	2	2	B.1.416	0.002538
S	677	Q677H	caG	caT	2	2	B.1.416.1	0.003125
S	677	Q677H	caG	caT	2	2	B.1.420	0.020833
S	677	Q677R	cAg	cGg	2	2	B.1.427	0.000101
S	677	Q677del	CAG	---	2	2	B.1.462	0.014493
S	677	Q677H	caG	caC	2	2	B.1.462	0.014493
S	677	Q677R	cAg	cGg	2	2	B.1.480	0.004975
S	677	Q677H	caG	caT	2	2	B.1.530	0.014286
S	677	Q677H	caG	caT	2	2	B.1.533	0.019231
S	677	Q677R	cAg	cGg	2	2	B.1.538	0.016129
S	677	Q677R	cAg	cGg	2	2	B.1.560	0.009259
S	677	Q677H	caG	caT	2	2	B.1.586	0.021978
S	677	Q677H	caG	caT	2	2	B.1.591	0.021277
S	677	Q677H	caG	caT	2	2	B.1.612	0.005305
S	677	Q677L	cAg	cTg	2	2	B.1.617.2	0.000008
S	677	Q677R	cAg	cGg	2	2	B.1.621	0.000177
S	677	Q677del	CAG	---	2	2	B.1.621	0.000177
S	677	Q677L	cAg	cTg	2	2	B.1.621	0.000177
S	677	Q677K	Cag	Aag	2	2	B.1.621.1	0.001012
S	677	Q677H	caG	caC	2	2	B.1.627	0.00404
S	677	Q677H	caG	caT	1	2	B.1.78	0.008547
S	677	Q677H	caG	caC	1	2	B.1.78	0.008547
S	677	Q677H	caG	caT	2	2	B.1.81	0.042553
S	677	Q677H	caG	caT	2	2	B.1.88.1	0.009615
S	677	Q677P	cAG	cCC	1	2	B.1.94	0.027027
S	677	Q677P	cAg	cCg	1	2	B.1.94	0.027027
S	677	Q677R	cAg	cGg	2	2	B.6	0.00182
S	677	Q677H	caG	caT	2	2	B.6.6	0.001778
S	677	Q677H	caG	caC	2	2	C.22	0.142857
S	677	Q677H	caG	caC	2	2	C.30	0.003454
S	677	Q677H	caG	caT	2	2	C.35	0.001548
S	677	Q677H	caG	caT	2	2	N.9	0.011905
S	677	Q677H	caG	caT	2	2	P.1.4	0.001953
S	677	Q677H	caG	caT	2	2	P.5	0.027397
S	677	Q677L	cAg	cTg	2	2	Q.1	0.000253
S	677	Q677Q	caG	caA	2	2	Q.3	0.00029
S	677	Q677del	CAG	---	1	1	A.1	0.000282
S	677	Q677H	caG	caT	1	1	A.6	0.005128
S	677	Q677H	caG	caT	1	1	AE.4	0.043478
S	677	Q677N	CaG	AaT	1	1	All	0
S	677	Q677W	CAg	TGg	1	1	All	0
S	677	Q677del2	cAG	c--	1	1	All	0
S	677	Q677S	CAg	TCg	1	1	All	0
S	677	Q677H	caG	caT	1	1	AT.1	0.005128
S	677	Q677H	caG	caC	1	1	AU.2	0.002421
S	677	Q677H	caG	caT	1	1	AU.3	0.00211
S	677	Q677Q	caG	caA	1	1	AY.1	0.000396
S	677	Q677L	cAg	cTg	1	1	AY.100	0.000046
S	677	Q677R	cAg	cGg	1	1	AY.100	0.000046
S	677	Q677R	cAg	cGg	1	1	AY.102	0.000027
S	677	Q677L	cAg	cTg	1	1	AY.102	0.000027
S	677	Q677R	cAg	cGg	1	1	AY.103	0.000006
S	677	Q677L	cAg	cTg	1	1	AY.103	0.000006
S	677	Q677R	cAg	cGg	1	1	AY.105	0.000643
S	677	Q677H	caG	caC	1	1	AY.107	0.000466
S	677	Q677H	caG	caT	1	1	AY.111	0.000183
S	677	Q677H	caG	caT	1	1	AY.114	0.000231
S	677	Q677P	cAg	cCg	1	1	AY.116	0.000287
S	677	Q677H	caG	caT	1	1	AY.116.1	0.000311
S	677	Q677R	cAg	cGg	1	1	AY.117	0.000085
S	677	Q677P	cAg	cCg	1	1	AY.117	0.000085
S	677	Q677E	Cag	Gag	1	1	AY.119	0.000035
S	677	Q677R	cAg	cGg	1	1	AY.119	0.000035
S	677	Q677H	caG	caT	1	1	AY.120.2	0.001285
S	677	Q677H	caG	caT	1	1	AY.120.2.1	0.000498
S	677	Q677R	cAg	cGg	1	1	AY.16.1	0.00047
S	677	Q677H	caG	caT	1	1	AY.19	0.00114
S	677	Q677L	cAg	cTg	1	1	AY.25	0.000006
S	677	Q677R	cAg	cGg	1	1	AY.28	0.00189
S	677	Q677L	cAg	cTg	1	1	AY.29	0.000016
S	677	Q677del	CAG	---	1	1	AY.3	0.00001
S	677	Q677H	caG	caT	1	1	AY.30	0.000396
S	677	Q677Y	CaG	TaC	1	1	AY.34	0.000097
S	677	Q677Q	caG	caA	1	1	AY.36	0.000148
S	677	Q677Q	caG	caA	1	1	AY.38	0.000499
S	677	Q677H	caG	caT	1	1	AY.38	0.000499
S	677	Q677W	CAg	TGg	1	1	AY.39	0.000025
S	677	Q677Q	caG	caA	1	1	AY.39.1	0.00004
S	677	Q677H	caG	caT	1	1	AY.39.1.1	0.000725
S	677	Q677H	caG	caC	1	1	AY.39.2	0.001541
S	677	Q677X	Cag	Tag	1	1	AY.4	0.000002
S	677	Q677H	caG	caC	1	1	AY.4.3	0.000842
S	677	Q677Q	caG	caA	1	1	AY.43	0.000004
S	677	Q677P	cAg	cCg	1	1	AY.43	0.000004
S	677	Q677L	cAg	cTg	1	1	AY.43	0.000004
S	677	Q677P	cAg	cCg	1	1	AY.44	0.000006
S	677	Q677Q	caG	caA	1	1	AY.45	0.000122
S	677	Q677R	cAg	cGg	1	1	AY.46	0.000104
S	677	Q677del	CAG	---	1	1	AY.46.1	0.001027
S	677	Q677R	cAg	cGg	1	1	AY.48	0.000465
S	677	Q677R	cAg	cGg	1	1	AY.5	0.000021
S	677	Q677del	CAG	---	1	1	AY.5	0.000021
S	677	Q677H	caG	caT	1	1	AY.51	0.000909
S	677	Q677H	caG	caC	1	1	AY.52	0.000814
S	677	Q677Q	caG	caA	1	1	AY.55	0.000917
S	677	Q677H	caG	caC	1	1	AY.56	0.001605
S	677	Q677H	caG	caT	1	1	AY.57	0.000656
S	677	Q677H	caG	caT	1	1	AY.64	0.000595
S	677	Q677P	cAg	cCg	1	1	AY.67	0.000464
S	677	Q677K	CaG	AaA	1	1	AY.67	0.000464
S	677	Q677H	caG	caT	1	1	AY.7.2	0.000559
S	677	Q677P	cAg	cCg	1	1	AY.75.1	0.00018
S	677	Q677H	caG	caC	1	1	AY.76	0.004831
S	677	Q677H	caG	caT	1	1	AY.79	0.001211
S	677	Q677del	CAG	---	1	1	AY.84	0.000437
S	677	Q677K	Cag	Aag	1	1	AY.85	0.000427
S	677	Q677K	Cag	Aag	1	1	AY.9.1	0.000084
S	677	Q677R	cAg	cGg	1	1	AY.9.1	0.000084
S	677	Q677del	CAG	---	1	1	AY.9.2	0.000037
S	677	Q677P	cAg	cCg	1	1	AY.9.2	0.000037
S	677	Q677H	caG	caT	1	1	AY.90	0.000684
S	677	Q677H	caG	caC	1	1	AY.95	0.000761
S	677	Q677H	caG	caC	1	1	AY.96	0.002075
S	677	Q677H	caG	caT	1	1	AY.97	0.001701
S	677	Q677del	CAG	---	1	1	AY.99	0.001049
S	677	Q677H	caG	caC	1	1	AY.99.1	0.001553
S	677	Q677P	cAg	cCg	1	1	B	0.000128
S	677	Q677Y	CaG	TaT	1	1	B.1	0.000009
S	677	Q677Q	caG	caA	1	1	B.1.1	0.000018
S	677	Q677E	Cag	Gag	1	1	B.1.1	0.000018
S	677	Q677Y	CaG	TaT	1	1	B.1.1	0.000018
S	677	Q677K	Cag	Aag	1	1	B.1.1.13	0.035714
S	677	Q677H	caG	caT	1	1	B.1.1.132	0.014925
S	677	Q677H	caG	caT	1	1	B.1.1.142	0.017544
S	677	Q677H	caG	caT	1	1	B.1.1.153	0.001095
S	677	Q677H	caG	caC	1	1	B.1.1.158	0.012195
S	677	Q677H	caG	caT	1	1	B.1.1.161	0.003534
S	677	Q677H	caG	caT	1	1	B.1.1.177	0.019231
S	677	Q677H	caG	caT	1	1	B.1.1.189	0.001513
S	677	Q677H	caG	caT	1	1	B.1.1.198	0.001468
S	677	Q677H	caG	caT	1	1	B.1.1.200	0.007463
S	677	Q677P	cAg	cCg	1	1	B.1.1.214	0.000055
S	677	Q677H	caG	caT	1	1	B.1.1.218	0.007692
S	677	Q677R	cAg	cGg	1	1	B.1.1.220	0.001859
S	677	Q677K	Cag	Aag	1	1	B.1.1.222	0.000204
S	677	Q677H	caG	caC	1	1	B.1.1.225	0.007194
S	677	Q677del	CAG	---	1	1	B.1.1.241	0.00207
S	677	Q677H	caG	caT	1	1	B.1.1.254	0.011236
S	677	Q677H	caG	caT	1	1	B.1.1.269	0.001353
S	677	Q677H	caG	caT	1	1	B.1.1.274	0.005051
S	677	Q677K	Cag	Aag	1	1	B.1.1.277	0.000759
S	677	Q677Y	CaG	TaT	1	1	B.1.1.284	0.000107
S	677	Q677H	caG	caC	1	1	B.1.1.291	0.000742
S	677	Q677R	cAg	cGg	1	1	B.1.1.291	0.000742
S	677	Q677H	caG	caT	1	1	B.1.1.298	0.000862
S	677	Q677H	caG	caC	1	1	B.1.1.304	0.002809
S	677	Q677H	caG	caT	1	1	B.1.1.309	0.005848
S	677	Q677H	caG	caT	1	1	B.1.1.311	0.000358
S	677	Q677Y	CaG	TaC	1	1	B.1.1.316	0.000925
S	677	Q677H	caG	caT	1	1	B.1.1.322	0.008772
S	677	Q677Q	caG	caA	1	1	B.1.1.335	0.012987
S	677	Q677H	caG	caT	1	1	B.1.1.353	0.020833
S	677	Q677del	CAG	---	1	1	B.1.1.354	0.004386
S	677	Q677X	Cag	Tag	1	1	B.1.1.368	0.003086
S	677	Q677H	caG	caT	1	1	B.1.1.369	0.000446
S	677	Q677del	CAG	---	1	1	B.1.1.372	0.000689
S	677	Q677H	caG	caT	1	1	B.1.1.378	0.007299
S	677	Q677L	cAg	cTg	1	1	B.1.1.39	0.00051
S	677	Q677del	CAG	---	1	1	B.1.1.39	0.00051
S	677	Q677K	Cag	Aag	1	1	B.1.1.406	0.006494
S	677	Q677H	caG	caT	1	1	B.1.1.409	0.002833
S	677	Q677H	caG	caT	1	1	B.1.1.419	0.007407
S	677	Q677H	caG	caT	1	1	B.1.1.421	0.030303
S	677	Q677H	caG	caC	1	1	B.1.1.432	0.001266
S	677	Q677X	Cag	Tag	1	1	B.1.1.432	0.001266
S	677	Q677H	caG	caT	1	1	B.1.1.45	0.014085
S	677	Q677H	caG	caT	1	1	B.1.1.459	0.015385
S	677	Q677H	caG	caT	1	1	B.1.1.46	0.004367
S	677	Q677H	caG	caT	1	1	B.1.1.47	0.005348
S	677	Q677H	caG	caC	1	1	B.1.1.482	0.023256
S	677	Q677del	CAG	---	1	1	B.1.1.482	0.023256
S	677	Q677P	cAg	cCg	1	1	B.1.1.507	0.008696
S	677	Q677X	Cag	Tag	1	1	B.1.1.519	0.00004
S	677	Q677H	caG	caT	1	1	B.1.1.523	0.001563
S	677	Q677Q	caG	caA	1	1	B.1.1.526	0.003546
S	677	Q677H	caG	caT	1	1	B.1.1.528	0.004808
S	677	Q677Q	caG	caA	1	1	B.1.1.63	0.000386
S	677	Q677Y	CaG	TaT	1	1	B.1.1.70	0.000341
S	677	Q677R	cAg	cGg	1	1	B.1.1.70	0.000341
S	677	Q677H	caG	caT	1	1	B.1.1.8	0.003584
S	677	Q677R	cAg	cGg	1	1	B.1.1.95	0.019608
S	677	Q677R	cAg	cGg	1	1	B.1.110.3	0.000718
S	677	Q677H	caG	caC	1	1	B.1.110.3	0.000718
S	677	Q677P	cAg	cCg	1	1	B.1.126	0.001276
S	677	Q677H	caG	caT	1	1	B.1.145	0.052632
S	677	Q677H	caG	caT	1	1	B.1.147	0.000756
S	677	Q677H	caG	caT	1	1	B.1.157	0.002985
S	677	Q677R	cAg	cGg	1	1	B.1.160	0.000031
S	677	Q677H	caG	caT	1	1	B.1.160.12	0.00641
S	677	Q677H	caG	caT	1	1	B.1.160.16	0.000929
S	677	Q677del	CAG	---	1	1	B.1.160.20	0.008929
S	677	Q677H	caG	caT	1	1	B.1.160.24	0.004425
S	677	Q677H	caG	caT	1	1	B.1.160.31	0.008065
S	677	Q677del	CAG	---	1	1	B.1.160.33	0.004425
S	677	Q677R	cAg	cGg	1	1	B.1.177	0.000013
S	677	Q677X	Cag	Tag	1	1	B.1.177	0.000013
S	677	Q677K	Cag	Aag	1	1	B.1.177	0.000013
S	677	Q677H	caG	caT	1	1	B.1.177.15	0.000631
S	677	Q677del	CAG	---	1	1	B.1.177.16	0.000664
S	677	Q677H	caG	caT	1	1	B.1.177.17	0.000821
S	677	Q677H	caG	caC	1	1	B.1.177.18	0.00116
S	677	Q677del1	Cag	-ag	1	1	B.1.177.31	0.011494
S	677	Q677L	cAg	cTg	1	1	B.1.177.33	0.001645
S	677	Q677del	CAG	---	1	1	B.1.177.4	0.000211
S	677	Q677H	caG	caT	1	1	B.1.177.42	0.000894
S	677	Q677H	caG	caT	1	1	B.1.177.43	0.001477
S	677	Q677H	caG	caT	1	1	B.1.177.52	0.001757
S	677	Q677H	caG	caC	1	1	B.1.177.54	0.000606
S	677	Q677H	caG	caT	1	1	B.1.177.57	0.000281
S	677	Q677H	caG	caC	1	1	B.1.177.65	0.000665
S	677	Q677H	caG	caT	1	1	B.1.177.72	0.00339
S	677	Q677del	CAG	---	1	1	B.1.177.75	0.001041
S	677	Q677H	caG	caC	1	1	B.1.177.82	0.000477
S	677	Q677H	caG	caC	1	1	B.1.177.9	0.001332
S	677	Q677H	caG	caT	1	1	B.1.195	0.005025
S	677	Q677del1	cAg	c-g	1	1	B.1.2	0.000009
S	677	Q677E	Cag	Gag	1	1	B.1.2	0.000009
S	677	Q677X	Cag	Tag	1	1	B.1.2	0.000009
S	677	Q677K	Cag	Aag	1	1	B.1.2	0.000009
S	677	Q677H	caG	caT	1	1	B.1.214	0.003663
S	677	Q677H	caG	caT	1	1	B.1.22	0.001318
S	677	Q677H	caG	caC	1	1	B.1.221.1	0.002907
S	677	Q677H	caG	caT	1	1	B.1.239	0.001221
S	677	Q677P	cAg	cCg	1	1	B.1.243	0.00007
S	677	Q677H	caG	caT	1	1	B.1.247	0.014925
S	677	Q677Q	caG	caA	1	1	B.1.258	0.000067
S	677	Q677del	CAG	---	1	1	B.1.258	0.000067
S	677	Q677H	caG	caT	1	1	B.1.258.11	0.000396
S	677	Q677H	caG	caT	1	1	B.1.260	0.003344
S	677	Q677R	cAg	cGg	1	1	B.1.260	0.003344
S	677	Q677R	cAg	cGg	1	1	B.1.264	0.012346
S	677	Q677H	caG	caT	1	1	B.1.293	0.0125
S	677	Q677H	caG	caT	1	1	B.1.306	0.005714
S	677	Q677H	caG	caT	1	1	B.1.326	0.007576
S	677	Q677del	CAG	---	1	1	B.1.351.2	0.000303
S	677	Q677H	caG	caC	1	1	B.1.36.12	0.009615
S	677	Q677R	cAg	cGg	1	1	B.1.36.29	0.000517
S	677	Q677R	cAg	cGg	1	1	B.1.36.31	0.001751
S	677	Q677Q	caG	caA	1	1	B.1.36.36	0.000602
S	677	Q677H	caG	caT	1	1	B.1.36.38	0.001642
S	677	Q677H	caG	caT	1	1	B.1.36.39	0.002217
S	677	Q677Q	caG	caA	1	1	B.1.366	0.004878
S	677	Q677H	caG	caT	1	1	B.1.371	0.001122
S	677	Q677P	cAg	cCg	1	1	B.1.375	0.00082
S	677	Q677Q	caG	caA	1	1	B.1.377	0.004566
S	677	Q677H	caG	caT	1	1	B.1.391	0.001127
S	677	Q677R	cAg	cGg	1	1	B.1.396	0.000706
S	677	Q677P	cAg	cCg	1	1	B.1.396	0.000706
S	677	Q677H	caG	caT	1	1	B.1.397	0.004854
S	677	Q677H	caG	caT	1	1	B.1.398	0.002976
S	677	Q677Q	caG	caA	1	1	B.1.400	0.000429
S	677	Q677Q	caG	caA	1	1	B.1.422	0.000812
S	677	Q677H	caG	caT	1	1	B.1.424	0.008065
S	677	Q677Y	CaG	TaT	1	1	B.1.425	0.002994
S	677	Q677X	Cag	Tag	1	1	B.1.425	0.002994
S	677	Q677L	cAg	cTg	1	1	B.1.427	0.00005
S	677	Q677H	caG	caT	1	1	B.1.428	0.00102
S	677	Q677L	cAg	cTg	1	1	B.1.429	0.000024
S	677	Q677P	cAg	cCg	1	1	B.1.429	0.000024
S	677	Q677K	Cag	Aag	1	1	B.1.429	0.000024
S	677	Q677X	Cag	Tag	1	1	B.1.429	0.000024
S	677	Q677del	CAG	---	1	1	B.1.429	0.000024
S	677	Q677H	caG	caT	1	1	B.1.433	0.003195
S	677	Q677H	caG	caT	1	1	B.1.442	0.035714
S	677	Q677H	caG	caT	1	1	B.1.445	0.011765
S	677	Q677H	caG	caT	1	1	B.1.450	0.011364
S	677	Q677H	caG	caT	1	1	B.1.452	0.013699
S	677	Q677Q	caG	caA	1	1	B.1.456	0.003268
S	677	Q677K	Cag	Aag	1	1	B.1.456	0.003268
S	677	Q677H	caG	caC	1	1	B.1.471	0.002732
S	677	Q677H	caG	caT	1	1	B.1.478	0.011765
S	677	Q677H	caG	caT	1	1	B.1.509	0.000866
S	677	Q677H	caG	caT	1	1	B.1.517	0.000427
S	677	Q677H	caG	caT	1	1	B.1.524	0.001406
S	677	Q677del2	cAG	c--	1	1	B.1.525	0.000113
S	677	Q677Y	CaG	TaC	1	1	B.1.525	0.000113
S	677	Q677K	Cag	Aag	1	1	B.1.526	0.000024
S	677	Q677H	caG	caC	1	1	B.1.555	0.022222
S	677	Q677H	caG	caT	1	1	B.1.567	0.003333
S	677	Q677H	caG	caT	1	1	B.1.568	0.001111
S	677	Q677P	cAg	cCg	1	1	B.1.571	0.009709
S	677	Q677H	caG	caC	1	1	B.1.574	0.002151
S	677	Q677H	caG	caT	1	1	B.1.575	0.000303
S	677	Q677H	caG	caT	1	1	B.1.575.2	0.004808
S	677	Q677P	cAg	cCg	1	1	B.1.580	0.004065
S	677	Q677P	cAg	cCg	1	1	B.1.582	0.000491
S	677	Q677del	CAG	---	1	1	B.1.596	0.000087
S	677	Q677S	CAg	TCg	1	1	B.1.596	0.000087
S	677	Q677H	caG	caT	1	1	B.1.606	0.006024
S	677	Q677Q	caG	caA	1	1	B.1.609	0.000479
S	677	Q677H	caG	caT	1	1	B.1.617.3	0.002985
S	677	Q677H	caG	caT	1	1	B.1.619	0.000871
S	677	Q677del	CAG	---	1	1	B.1.620	0.000946
S	677	Q677P	cAg	cCg	1	1	B.1.623	0.000536
S	677	Q677del	CAG	---	1	1	B.1.627	0.00202
S	677	Q677H	caG	caC	1	1	B.1.629	0.013333
S	677	Q677H	caG	caT	1	1	B.1.630	0.005236
S	677	Q677H	caG	caC	1	1	B.1.636	0.006711
S	677	Q677del	CAG	---	1	1	B.1.638	0.052632
S	677	Q677H	caG	caC	1	1	B.1.94	0.027027
S	677	Q677H	caG	caC	1	1	B.10	0.008264
S	677	Q677H	caG	caT	1	1	B.55	0.00295
S	677	Q677X	Cag	Tag	1	1	B.55	0.00295
S	677	Q677K	Cag	Aag	1	1	B.6	0.00091
S	677	Q677R	cAg	cGg	1	1	B.6.6	0.000889
S	677	Q677H	caG	caC	1	1	C.1	0.002392
S	677	Q677H	caG	caC	1	1	C.1.1	0.076923
S	677	Q677H	caG	caT	1	1	C.1.2	0.004255
S	677	Q677H	caG	caT	1	1	C.18	0.002591
S	677	Q677H	caG	caT	1	1	C.26	0.007353
S	677	Q677del	CAG	---	1	1	C.37	0.000116
S	677	Q677R	cAg	cGg	1	1	C.37	0.000116
S	677	Q677H	caG	caC	1	1	C.37.1	0.002618
S	677	Q677X	Cag	Tag	1	1	D.2	0.000075
S	677	Q677E	Cag	Gag	1	1	D.2	0.000075
S	677	Q677K	Cag	Aag	1	1	D.2	0.000075
S	677	Q677H	caG	caT	1	1	K.1	0.02381
S	677	Q677N	CaG	AaT	1	1	K.1	0.02381
S	677	Q677K	Cag	Aag	1	1	K.1	0.02381
S	677	Q677H	caG	caT	1	1	L.2	0.011364
S	677	Q677L	cAg	cTg	1	1	P.1	0.000016
S	677	Q677Q	caG	caA	1	1	P.1.1	0.000318
S	677	Q677del1	Cag	-ag	1	1	P.1.10.1	0.00813
S	677	Q677del	CAG	---	1	1	P.1.13	0.000898
S	677	Q677L	cAg	cTg	1	1	P.1.7	0.000319
S	677	Q677H	caG	caT	1	1	P.1.8	0.004785
S	677	Q677K	Cag	Aag	1	1	P.6	0.003145
S	677	Q677H	caG	caT	1	1	Q.4	0.000455
S	677	Q677H	caG	caT	1	1	Q.6	0.006623
S	677	Q677R	cAg	cGg	1	1	Q.8	0.000165
S	677	Q677H	caG	caT	1	1	W.4	0.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.