CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 654 & Codon = Caa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	654	E654Q		nonsyn	Gaa	Caa	1478	1478	1	23522-23524

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	654	E654Q	Gaa	Caa	1478	1478	All	0.000283
S	654	E654Q	Gaa	Caa	197	197	B.1.1.277	0.149469
S	654	E654Q	Gaa	Caa	170	170	AY.4	0.000265
S	654	E654Q	Gaa	Caa	134	134	B.1.1.7	0.00012
S	654	E654Q	Gaa	Caa	122	122	B.1.499	0.128151
S	654	E654Q	Gaa	Caa	85	85	AY.98.1	0.004117
S	654	E654Q	Gaa	Caa	78	78	B.1.2	0.000687
S	654	E654Q	Gaa	Caa	68	68	B.1	0.000623
S	654	E654Q	Gaa	Caa	68	68	B.1.1.189	0.102874
S	654	E654Q	Gaa	Caa	68	68	B.1.36.24	0.419753
S	654	E654Q	Gaa	Caa	45	45	B.1.526	0.001058
S	654	E654Q	Gaa	Caa	45	45	B.1.562	0.833333
S	654	E654Q	Gaa	Caa	42	42	B.1.177	0.000553
S	654	E654Q	Gaa	Caa	41	41	P.1.7	0.013091
S	654	E654Q	Gaa	Caa	40	40	AY.29	0.000631
S	654	E654Q	Gaa	Caa	39	39	B.1.1	0.000707
S	654	E654Q	Gaa	Caa	28	28	B.1.1.222	0.005712
S	654	E654Q	Gaa	Caa	19	19	B.1.627	0.038384
S	654	E654Q	Gaa	Caa	16	16	AY.25	0.000096
S	654	E654Q	Gaa	Caa	16	16	B.1.1.174	0.054054
S	654	E654Q	Gaa	Caa	13	13	AY.44	0.000079
S	654	E654Q	Gaa	Caa	11	11	AY.47	0.000342
S	654	E654Q	Gaa	Caa	10	10	B.1.617.2	0.000038
S	654	E654Q	Gaa	Caa	10	10	Q.6	0.066225
S	654	E654Q	Gaa	Caa	7	7	AY.26	0.000198
S	654	E654Q	Gaa	Caa	6	6	AY.23.1	0.002504
S	654	E654Q	Gaa	Caa	6	6	P.1	0.000095
S	654	E654Q	Gaa	Caa	5	5	AY.39.1	0.000198
S	654	E654Q	Gaa	Caa	5	5	B.1.351	0.000149
S	654	E654Q	Gaa	Caa	4	4	AY.103	0.000025
S	654	E654Q	Gaa	Caa	4	4	B.1.456	0.013072
S	654	E654Q	Gaa	Caa	4	4	B.1.596	0.000349
S	654	E654Q	Gaa	Caa	4	4	B.1.621	0.000354
S	654	E654Q	Gaa	Caa	3	3	AY.102	0.00008
S	654	E654Q	Gaa	Caa	3	3	AY.61	0.000314
S	654	E654Q	Gaa	Caa	3	3	B.1.1.519	0.000119
S	654	E654Q	Gaa	Caa	3	3	B.1.1.526	0.010638
S	654	E654Q	Gaa	Caa	2	2	AY.29.1	0.000441
S	654	E654Q	Gaa	Caa	2	2	B.1.351.2	0.000605
S	654	E654Q	Gaa	Caa	2	2	B.1.36	0.000292
S	654	E654Q	Gaa	Caa	2	2	B.1.495	0.018182
S	654	E654Q	Gaa	Caa	2	2	B.1.617.1	0.000258
S	654	E654Q	Gaa	Caa	2	2	Q.3	0.00029
S	654	E654Q	Gaa	Caa	1	1	A.2	0.000662
S	654	E654Q	Gaa	Caa	1	1	AY.100	0.000046
S	654	E654Q	Gaa	Caa	1	1	AY.110	0.000113
S	654	E654Q	Gaa	Caa	1	1	AY.113	0.000142
S	654	E654Q	Gaa	Caa	1	1	AY.119	0.000035
S	654	E654Q	Gaa	Caa	1	1	AY.120	0.000037
S	654	E654Q	Gaa	Caa	1	1	AY.16	0.00038
S	654	E654Q	Gaa	Caa	1	1	AY.3	0.00001
S	654	E654Q	Gaa	Caa	1	1	AY.3.1	0.000085
S	654	E654Q	Gaa	Caa	1	1	AY.34.1	0.00051
S	654	E654Q	Gaa	Caa	1	1	AY.4.2	0.000022
S	654	E654Q	Gaa	Caa	1	1	AY.42	0.00004
S	654	E654Q	Gaa	Caa	1	1	AY.43	0.000004
S	654	E654Q	Gaa	Caa	1	1	AY.46	0.000104
S	654	E654Q	Gaa	Caa	1	1	AY.54	0.000095
S	654	E654Q	Gaa	Caa	1	1	AY.67	0.000464
S	654	E654Q	Gaa	Caa	1	1	AY.68	0.000274
S	654	E654Q	Gaa	Caa	1	1	AY.7	0.000196
S	654	E654Q	Gaa	Caa	1	1	AY.74	0.000116
S	654	E654Q	Gaa	Caa	1	1	AY.75	0.000056
S	654	E654Q	Gaa	Caa	1	1	AY.75.1	0.00018
S	654	E654Q	Gaa	Caa	1	1	B	0.000128
S	654	E654Q	Gaa	Caa	1	1	B.1.1.134	0.011364
S	654	E654Q	Gaa	Caa	1	1	B.1.1.231	0.003096
S	654	E654Q	Gaa	Caa	1	1	B.1.1.28	0.000311
S	654	E654Q	Gaa	Caa	1	1	B.1.1.318	0.000302
S	654	E654Q	Gaa	Caa	1	1	B.1.1.348	0.000796
S	654	E654Q	Gaa	Caa	1	1	B.1.1.37	0.000193
S	654	E654Q	Gaa	Caa	1	1	B.1.1.409	0.002833
S	654	E654Q	Gaa	Caa	1	1	B.1.1.424	0.045455
S	654	E654Q	Gaa	Caa	1	1	B.1.1.57	0.011494
S	654	E654Q	Gaa	Caa	1	1	B.1.1.59	0.006494
S	654	E654Q	Gaa	Caa	1	1	B.1.177.7	0.000165
S	654	E654Q	Gaa	Caa	1	1	B.1.243	0.00007
S	654	E654Q	Gaa	Caa	1	1	B.1.336	0.002439
S	654	E654Q	Gaa	Caa	1	1	B.1.36.31	0.001751
S	654	E654Q	Gaa	Caa	1	1	B.1.369	0.000285
S	654	E654Q	Gaa	Caa	1	1	B.1.459	0.004082
S	654	E654Q	Gaa	Caa	1	1	B.1.524	0.001406
S	654	E654Q	Gaa	Caa	1	1	B.1.561	0.000397
S	654	E654Q	Gaa	Caa	1	1	B.1.576	0.000907
S	654	E654Q	Gaa	Caa	1	1	B.1.637	0.000073
S	654	E654Q	Gaa	Caa	1	1	K.1	0.02381
S	654	E654Q	Gaa	Caa	1	1	P.2	0.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.