CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 631 | P631S | nonsyn | Cct | Tct | 1704 | 1702 | 0.998826 | 23453-23455 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 631 | P631S | Cct | Tct | 1702 | 1704 | All | 0.000326 |
S | 631 | P631S | Cct | Tct | 624 | 624 | B.1.1.7 | 0.000559 |
S | 631 | P631S | Cct | Tct | 284 | 284 | B.1.2 | 0.002501 |
S | 631 | P631S | Cct | Tct | 190 | 190 | AY.4 | 0.000296 |
S | 631 | P631S | Cct | Tct | 42 | 42 | B.1 | 0.000385 |
S | 631 | P631S | Cct | Tct | 35 | 35 | B.1.177 | 0.000461 |
S | 631 | P631S | Cct | Tct | 30 | 30 | AY.103 | 0.000186 |
S | 631 | P631S | Cct | Tct | 28 | 28 | AY.43 | 0.000124 |
S | 631 | P631S | Cct | Tct | 26 | 26 | B.1.617.2 | 0.000098 |
S | 631 | P631S | Cct | Tct | 25 | 25 | B.1.160 | 0.00078 |
S | 631 | P631S | Cct | Tct | 20 | 20 | B.1.1.519 | 0.000794 |
S | 631 | P631S | Cct | Tct | 17 | 17 | AY.3 | 0.000169 |
S | 631 | P631S | Cct | Tct | 16 | 16 | AY.25 | 0.000096 |
S | 631 | P631S | Cct | Tct | 16 | 16 | AY.44 | 0.000097 |
S | 631 | P631S | Cct | Tct | 14 | 14 | AY.4.2 | 0.000304 |
S | 631 | P631S | Cct | Tct | 14 | 14 | P.1 | 0.000221 |
S | 631 | P631S | Cct | Tct | 12 | 12 | AY.13 | 0.001932 |
S | 631 | P631S | Cct | Tct | 12 | 12 | B.1.1.432 | 0.01519 |
S | 631 | P631S | Cct | Tct | 12 | 12 | B.1.526 | 0.000282 |
S | 631 | P631S | Cct | Tct | 12 | 12 | Q.1 | 0.001516 |
S | 631 | P631S | Cct | Tct | 10 | 10 | B.1.1 | 0.000181 |
S | 631 | P631S | Cct | Tct | 10 | 10 | B.1.177.86 | 0.001835 |
S | 631 | P631S | Cct | Tct | 9 | 9 | AY.5 | 0.000186 |
S | 631 | P631S | Cct | Tct | 8 | 8 | C.36 | 0.007286 |
S | 631 | P631S | Cct | Tct | 7 | 7 | B.1.1.374 | 0.016627 |
S | 631 | P631S | Cct | Tct | 6 | 6 | AY.23.1 | 0.002504 |
S | 631 | P631S | Cct | Tct | 6 | 6 | B.1.110.2 | 1 |
S | 631 | P631S | Cct | Tct | 6 | 6 | B.1.243 | 0.000418 |
S | 631 | P631S | Cct | Tct | 6 | 6 | B.1.619.1 | 0.003849 |
S | 631 | P631S | Cct | Tct | 5 | 5 | AY.29 | 0.000079 |
S | 631 | P631S | Cct | Tct | 5 | 5 | AY.39 | 0.000124 |
S | 631 | P631S | Cct | Tct | 5 | 5 | AY.39.1 | 0.000198 |
S | 631 | P631S | Cct | Tct | 5 | 5 | AY.98.1 | 0.000242 |
S | 631 | P631S | Cct | Tct | 5 | 5 | B.1.160.15 | 0.024752 |
S | 631 | P631S | Cct | Tct | 5 | 5 | B.1.36.29 | 0.002587 |
S | 631 | P631S | Cct | Tct | 5 | 5 | B.1.596 | 0.000436 |
S | 631 | P631S | Cct | Tct | 5 | 5 | C.37 | 0.00058 |
S | 631 | P631S | Cct | Tct | 2 | 4 | 0.111111 | |
S | 631 | P631S | Cct | Tct | 4 | 4 | AY.61 | 0.000419 |
S | 631 | P631S | Cct | Tct | 4 | 4 | AY.7.1 | 0.000451 |
S | 631 | P631S | Cct | Tct | 4 | 4 | AY.74 | 0.000463 |
S | 631 | P631S | Cct | Tct | 4 | 4 | B.1.177.81 | 0.000757 |
S | 631 | P631S | Cct | Tct | 4 | 4 | B.1.351 | 0.000119 |
S | 631 | P631S | Cct | Tct | 3 | 3 | AY.102 | 0.00008 |
S | 631 | P631S | Cct | Tct | 3 | 3 | AY.26 | 0.000085 |
S | 631 | P631S | Cct | Tct | 3 | 3 | B | 0.000383 |
S | 631 | P631S | Cct | Tct | 3 | 3 | B.1.1.134 | 0.034091 |
S | 631 | P631S | Cct | Tct | 3 | 3 | B.1.177.6 | 0.00293 |
S | 631 | P631S | Cct | Tct | 3 | 3 | B.1.438.1 | 0.000322 |
S | 631 | P631S | Cct | Tct | 3 | 3 | B.1.525 | 0.000339 |
S | 631 | P631S | Cct | Tct | 3 | 3 | P.1.14 | 0.000143 |
S | 631 | P631S | Cct | Tct | 3 | 3 | P.1.15 | 0.000697 |
S | 631 | P631S | Cct | Tct | 3 | 3 | P.2 | 0.00056 |
S | 631 | P631S | Cct | Tct | 2 | 2 | A.1 | 0.000564 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.110 | 0.000225 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.118 | 0.000125 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.12 | 0.000632 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.120.1 | 0.000642 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.21 | 0.003795 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.23 | 0.000139 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.45 | 0.000243 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.46 | 0.000208 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.47 | 0.000062 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.6 | 0.000082 |
S | 631 | P631S | Cct | Tct | 2 | 2 | AY.75 | 0.000112 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.1.189 | 0.003026 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.1.230 | 0.018349 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.1.348 | 0.001592 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.1.37 | 0.000386 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.1.397 | 0.004505 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.1.434 | 0.000697 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.160.26 | 0.004843 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.468 | 0.011429 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.497 | 0.00063 |
S | 631 | P631S | Cct | Tct | 2 | 2 | B.1.617.1 | 0.000258 |
S | 631 | P631S | Cct | Tct | 2 | 2 | C.36.3 | 0.001134 |
S | 631 | P631S | Cct | Tct | 2 | 2 | Q.8 | 0.00033 |
S | 631 | P631S | Cct | Tct | 1 | 1 | A.5 | 0.001923 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AE.8 | 0.000489 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AU.2 | 0.002421 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.100 | 0.000046 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.113 | 0.000142 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.121 | 0.000135 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.20 | 0.000039 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.29.1 | 0.000221 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.33 | 0.000067 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.36 | 0.000148 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.46.5 | 0.000198 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.51 | 0.000909 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.54 | 0.000095 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.69 | 0.000187 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.7.2 | 0.000559 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.9 | 0.000068 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.9.1 | 0.000084 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.9.2 | 0.000037 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.93 | 0.000273 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.94 | 0.000443 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AY.97 | 0.001701 |
S | 631 | P631S | Cct | Tct | 1 | 1 | AZ.1 | 0.000867 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.1 | 0.000327 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.170 | 0.001247 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.220 | 0.001859 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.222 | 0.000204 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.232 | 0.001815 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.269 | 0.001353 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.28 | 0.000311 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.284 | 0.000107 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.289 | 0.002083 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.318 | 0.000302 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.368 | 0.003086 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.39 | 0.00051 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.1.461 | 0.012048 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.111 | 0.001175 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.177.16 | 0.000664 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.177.21 | 0.000076 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.223 | 0.002778 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.240 | 0.000216 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.258.17 | 0.000104 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.265 | 0.001271 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.305 | 0.002151 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.311 | 0.000275 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.349 | 0.000715 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.36.31 | 0.001751 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.36.8 | 0.001 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.403 | 0.003268 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.453 | 0.003236 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.546 | 0.003704 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.551 | 0.00129 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.561 | 0.000397 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.565 | 0.00081 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.609 | 0.000479 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.612 | 0.002653 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.621 | 0.000089 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.623 | 0.000536 |
S | 631 | P631S | Cct | Tct | 1 | 1 | B.1.637 | 0.000073 |
S | 631 | P631S | Cct | Tct | 1 | 1 | D.2 | 0.000075 |
S | 631 | P631S | Cct | Tct | 1 | 1 | N.5 | 0.001767 |
S | 631 | P631S | Cct | Tct | 1 | 1 | P.1.10 | 0.000269 |
S | 631 | P631S | Cct | Tct | 1 | 1 | P.7 | 0.004367 |
S | 631 | P631S | Cct | Tct | 1 | 1 | Q.3 | 0.000145 |
S | 631 | P631S | Cct | Tct | 1 | 1 | W.1 | 0.008696 |
S | 631 | P631S | Cct | Tct | 1 | 1 | Z.1 | 0.00289 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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