CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 585

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S585L585FnonsynCttTtt11731173123315-23317
S585L585LsynctTctC3512920.83190923315-23317
S585L585LsynctTctA351470.13390323315-23317
S585L585LsynctTctG351120.03418823315-23317
S585L585InonsynCttAtt34330.97058823315-23317
S585L585InonsynCtTAtA3410.029411823315-23317
S585L585deldelCTT---1010123315-23317
S585L585PnonsyncTtcCt66123315-23317
S585L585VnonsynCttGtt44123315-23317
S585L585del1delCtt-tt210.523315-23317
S585L585del1delcTtc-t210.523315-23317
S585L585RnonsyncTtcGt11123315-23317
S585L585del2delCTt--t11123315-23317
S585L585HnonsyncTtcAt11123315-23317

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S585L585FCttTtt11731173All0.000224
S585L585FCttTtt380380B.1.1.70.00034
S585L585LctTctC292351All0.000056
S585L585LctTctA47351All0.000009
S585L585LctTctG12351All0.000002
S585L585FCttTtt198198AY.40.000308
S585L585LctTctC180189AY.40.00028
S585L585LctTctA8189AY.40.000012
S585L585LctTctG1189AY.40.000002
S585L585FCttTtt120120B.1.1.1570.109589
S585L585FCttTtt5757AY.390.001409
S585L585FCttTtt4444B.10.000403
S585L585FCttTtt4141B.1.10.000744
S585L585ICttAtt3334All0.000006
S585L585ICtTAtA134All0
S585L585LctTctC3333B.1.2400.007114
S585L585FCttTtt2929C.1.20.123404
S585L585FCttTtt2222B.1.20.000194
S585L585FCttTtt2222B.1.5960.001917
S585L585LctTctA1019B.1.617.20.000038
S585L585LctTctC619B.1.617.20.000023
S585L585LctTctG319B.1.617.20.000011
S585L585FCttTtt1818B.1.258.220.048
S585L585LctTctC1216AY.30.000119
S585L585LctTctA216AY.30.00002
S585L585LctTctG216AY.30.00002
S585L585FCttTtt1414B.1.5950.003653
S585L585LctTctC713AY.290.00011
S585L585LctTctA613AY.290.000095
S585L585FCttTtt1313AY.440.000079
S585L585LctTctC1111B.1.1.370.002122
S585L585FCttTtt1111B.1.617.20.000041
S585L585delCTT---1010All0.000002
S585L585FCttTtt1010AY.250.00006
S585L585FCttTtt1010AY.430.000044
S585L585FCttTtt1010AY.60.000411
S585L585LctTctC610B.1.1.70.000005
S585L585LctTctA310B.1.1.70.000003
S585L585LctTctG110B.1.1.70.000001
S585L585FCttTtt99B.1.1770.000119
S585L585FCttTtt88B.1.1.5190.000318
S585L585ICttAtt77B.1.160.150.034653
S585L585PcTtcCt66All0.000001
S585L585FCttTtt66B.1.1.3020.012448
S585L585LctTctA55A.300.714286
S585L585FCttTtt55AY.1190.000177
S585L585LctTctC45AY.250.000024
S585L585LctTctA15AY.250.000006
S585L585LctTctC55AY.430.000022
S585L585LctTctA45AY.450.000487
S585L585LctTctC15AY.450.000122
S585L585ICttAtt55B.10.000046
S585L585FCttTtt55B.1.1.280.001556
S585L585FCttTtt55B.1.2940.16129
S585L585FCttTtt55B.1.5800.020325
S585L585FCttTtt55C.36.3.10.013587
S585L585VCttGtt44All0.000001
S585L585FCttTtt44AY.30.00004
S585L585FCttTtt44B.1.1.2940.005063
S585L585FCttTtt44B.1.2650.005083
S585L585FCttTtt44B.1.3460.005242
S585L585FCttTtt44B.1.3510.000119
S585L585FCttTtt44D.20.0003
S585L585FCttTtt44P.10.000063
S585L585VCttGtt44P.10.000063
S585L585FCttTtt33AY.10.001187
S585L585LctTctA23AY.470.000062
S585L585LctTctC13AY.470.000031
S585L585FCttTtt33AY.9.10.000251
S585L585FCttTtt33B0.000383
S585L585LctTctC23B.10.000018
S585L585LctTctA13B.10.000009
S585L585LctTctC33B.1.10.000054
S585L585LctTctA23B.1.20.000018
S585L585LctTctC13B.1.20.000009
S585L585LctTctC33B.1.3510.000089
S585L585FCttTtt33B.1.4290.000071
S585L585FCttTtt33B.1.5230.007353
S585L585del1Ctt-tt12All0
S585L585del1cTtc-t12All0
S585L585LctTctG12AY.1000.000046
S585L585LctTctC12AY.1000.000046
S585L585LctTctC22AY.1030.000012
S585L585ICttAtt22AY.1030.000012
S585L585FCttTtt22AY.1030.000012
S585L585ICtTAtA12AY.1180.000063
S585L585ICttAtt12AY.1180.000063
S585L585FCttTtt22AY.1200.000074
S585L585FCttTtt22AY.290.000032
S585L585LctTctC22AY.340.000194
S585L585FCttTtt22AY.420.00008
S585L585ICttAtt22AY.430.000009
S585L585LctTctG12AY.440.000006
S585L585LctTctA12AY.440.000006
S585L585LctTctC22AY.50.000041
S585L585FCttTtt22AY.50.000041
S585L585FCttTtt22B.1.1.2140.000111
S585L585FCttTtt22B.1.1.3050.007722
S585L585FCttTtt22B.1.1.330.000842
S585L585FCttTtt22B.1.1.4200.002012
S585L585ICttAtt22B.1.1.70.000002
S585L585PcTtcCt22B.1.1.70.000002
S585L585FCttTtt22B.1.177.730.001133
S585L585FCttTtt22B.1.177.750.002081
S585L585FCttTtt22B.1.3110.000549
S585L585FCttTtt22B.1.360.000292
S585L585FCttTtt22B.1.3690.00057
S585L585FCttTtt22C.370.000232
S585L585ICttAtt11A0.000387
S585L585FCttTtt11A.210.00277
S585L585RcTtcGt11All0
S585L585HcTtcAt11All0
S585L585del2CTt--t11All0
S585L585FCttTtt11AY.1020.000027
S585L585FCttTtt11AY.1060.000335
S585L585FCttTtt11AY.1160.000287
S585L585LctTctC11AY.1170.000085
S585L585FCttTtt11AY.120.20.001285
S585L585LctTctC11AY.1210.000135
S585L585FCttTtt11AY.200.000039
S585L585FCttTtt11AY.230.00007
S585L585FCttTtt11AY.270.000065
S585L585FCttTtt11AY.29.10.000221
S585L585FCttTtt11AY.3.10.000085
S585L585ICttAtt11AY.330.000067
S585L585FCttTtt11AY.330.000067
S585L585delCTT---11AY.380.000499
S585L585ICttAtt11AY.40.000002
S585L585delCTT---11AY.40.000002
S585L585delCTT---11AY.430.000004
S585L585PcTtcCt11AY.430.000004
S585L585FCttTtt11AY.450.000122
S585L585LctTctC11AY.46.20.000635
S585L585LctTctA11AY.46.60.000072
S585L585ICttAtt11AY.520.000814
S585L585ICttAtt11AY.600.000938
S585L585LctTctC11AY.670.000464
S585L585FCttTtt11AY.700.000209
S585L585PcTtcCt11AY.750.000056
S585L585FCttTtt11AY.9.20.000037
S585L585FCttTtt11AZ.10.000867
S585L585ICttAtt11AZ.30.00152
S585L585ICttAtt11B0.000128
S585L585del1Ctt-tt11B.10.000009
S585L585FCttTtt11B.1.1.1170.009709
S585L585delCTT---11B.1.1.1390.022727
S585L585FCttTtt11B.1.1.1760.000439
S585L585FCttTtt11B.1.1.2220.000204
S585L585FCttTtt11B.1.1.2840.000107
S585L585ICttAtt11B.1.1.2880.001916
S585L585FCttTtt11B.1.1.3510.002793
S585L585FCttTtt11B.1.1.370.000193
S585L585FCttTtt11B.1.1.3710.010417
S585L585FCttTtt11B.1.1.3760.005952
S585L585FCttTtt11B.1.1.390.00051
S585L585FCttTtt11B.1.1.3980.003226
S585L585FCttTtt11B.1.1.4020.011111
S585L585FCttTtt11B.1.1.4340.000349
S585L585LctTctG11B.1.1.5190.00004
S585L585delCTT---11B.1.1.70.000001
S585L585del2CTt--t11B.1.1.70.000001
S585L585FCttTtt11B.1.1.710.006061
S585L585FCttTtt11B.1.130.002375
S585L585FCttTtt11B.1.160.160.000929
S585L585FCttTtt11B.1.160.90.007194
S585L585PcTtcCt11B.1.1770.000013
S585L585ICttAtt11B.1.1770.000013
S585L585LctTctC11B.1.177.60.000977
S585L585FCttTtt11B.1.177.650.000665
S585L585FCttTtt11B.1.177.810.000189
S585L585delCTT---11B.1.2340.000132
S585L585FCttTtt11B.1.2430.00007
S585L585LctTctA11B.1.2430.00007
S585L585del1cTtc-t11B.1.2470.014925
S585L585FCttTtt11B.1.2580.000067
S585L585ICttAtt11B.1.3010.005917
S585L585FCttTtt11B.1.3350.010309
S585L585FCttTtt11B.1.351.50.0006
S585L585HcTtcAt11B.1.360.000146
S585L585FCttTtt11B.1.36.310.001751
S585L585FCttTtt11B.1.3670.000792
S585L585FCttTtt11B.1.3750.00082
S585L585FCttTtt11B.1.390.003906
S585L585FCttTtt11B.1.4110.003704
S585L585LctTctC11B.1.438.10.000107
S585L585RcTtcGt11B.1.4620.007246
S585L585FCttTtt11B.1.5260.000024
S585L585FCttTtt11B.1.5610.000397
S585L585delCTT---11B.1.5640.000426
S585L585FCttTtt11B.1.5700.002941
S585L585ICttAtt11B.1.5960.000087
S585L585FCttTtt11B.1.6090.000479
S585L585LctTctC11B.1.6090.000479
S585L585FCttTtt11B.1.617.10.000129
S585L585ICttAtt11B.1.617.20.000004
S585L585delCTT---11B.1.617.20.000004
S585L585delCTT---11B.1.6200.000946
S585L585ICttAtt11B.1.6230.000536
S585L585LctTctC11B.1.6280.000352
S585L585FCttTtt11B.6.60.000889
S585L585FCttTtt11C.10.002392
S585L585FCttTtt11C.360.000911
S585L585FCttTtt11D.50.004975
S585L585ICttAtt11P.10.000016
S585L585LctTctG11P.10.000016
S585L585LctTctG11P.1.120.000484
S585L585LctTctC11P.1.140.000048
S585L585PcTtcCt11P.1.170.000162
S585L585LctTctC11P.1.17.10.000875
S585L585FCttTtt11P.20.000187
S585L585FCttTtt11Q.30.000145
S585L585delCTT---11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.