CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 583 | E583D | nonsyn | gaG | gaC | 12586 | 4309 | 0.342365 | 23309-23311 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 583 | E583D | gaG | gaC | 4309 | 12586 | All | 0.000824 |
S | 583 | E583D | gaG | gaC | 713 | 3630 | B.1.1.7 | 0.000638 |
S | 583 | E583D | gaG | gaC | 861 | 861 | B.1.177.18 | 0.99884 |
S | 583 | E583D | gaG | gaC | 95 | 709 | AY.4 | 0.000148 |
S | 583 | E583D | gaG | gaC | 698 | 699 | B.1.177.19 | 0.998569 |
S | 583 | E583D | gaG | gaC | 659 | 659 | B.1.177.20 | 1 |
S | 583 | E583D | gaG | gaC | 71 | 478 | AY.43 | 0.000315 |
S | 583 | E583D | gaG | gaC | 274 | 344 | B.1.177 | 0.003608 |
S | 583 | E583D | gaG | gaC | 120 | 341 | B.1.617.2 | 0.000452 |
S | 583 | E583D | gaG | gaC | 45 | 210 | AY.103 | 0.000279 |
S | 583 | E583D | gaG | gaC | 55 | 206 | AY.25 | 0.000331 |
S | 583 | E583D | gaG | gaC | 34 | 205 | B.1.2 | 0.000299 |
S | 583 | E583D | gaG | gaC | 46 | 181 | P.1 | 0.000725 |
S | 583 | E583D | gaG | gaC | 49 | 164 | AY.44 | 0.000298 |
S | 583 | E583D | gaG | gaC | 23 | 133 | B.1 | 0.000211 |
S | 583 | E583D | gaG | gaC | 8 | 97 | AY.102 | 0.000212 |
S | 583 | E583D | gaG | gaC | 45 | 92 | B.1.258 | 0.002995 |
S | 583 | E583D | gaG | gaC | 36 | 73 | AY.121 | 0.004871 |
S | 583 | E583D | gaG | gaC | 1 | 70 | Q.8 | 0.000165 |
S | 583 | E583D | gaG | gaC | 13 | 65 | B.1.160 | 0.000405 |
S | 583 | E583D | gaG | gaC | 21 | 64 | AY.98.1 | 0.001017 |
S | 583 | E583D | gaG | gaC | 6 | 62 | B.1.243 | 0.000418 |
S | 583 | E583D | gaG | gaC | 22 | 59 | B.1.1 | 0.000399 |
S | 583 | E583D | gaG | gaC | 22 | 51 | AY.4.2 | 0.000477 |
S | 583 | E583D | gaG | gaC | 16 | 49 | AY.39 | 0.000395 |
S | 583 | E583D | gaG | gaC | 16 | 48 | B.1.526 | 0.000376 |
S | 583 | E583D | gaG | gaC | 18 | 45 | AY.3 | 0.000179 |
S | 583 | E583D | gaG | gaC | 25 | 42 | AY.26 | 0.000708 |
S | 583 | E583D | gaG | gaC | 1 | 41 | AY.42 | 0.00004 |
S | 583 | E583D | gaG | gaC | 10 | 36 | B.1.351 | 0.000297 |
S | 583 | E583D | gaG | gaC | 1 | 34 | AY.20 | 0.000039 |
S | 583 | E583D | gaG | gaC | 21 | 32 | AY.100 | 0.000966 |
S | 583 | E583D | gaG | gaC | 13 | 31 | B.1.429 | 0.000306 |
S | 583 | E583D | gaG | gaC | 8 | 30 | AY.29 | 0.000126 |
S | 583 | E583D | gaG | gaC | 5 | 28 | AY.33 | 0.000334 |
S | 583 | E583D | gaG | gaC | 1 | 28 | AY.34 | 0.000097 |
S | 583 | E583D | gaG | gaC | 8 | 27 | AY.5 | 0.000165 |
S | 583 | E583D | gaG | gaC | 1 | 27 | B.1.177.81 | 0.000189 |
S | 583 | E583D | gaG | gaC | 26 | 26 | AY.65 | 0.013859 |
S | 583 | E583D | gaG | gaC | 14 | 26 | AY.75 | 0.000784 |
S | 583 | E583D | gaG | gaC | 1 | 26 | B.1.369 | 0.000285 |
S | 583 | E583D | gaG | gaC | 17 | 24 | AY.39.1 | 0.000673 |
S | 583 | E583D | gaG | gaC | 2 | 23 | D.2 | 0.00015 |
S | 583 | E583D | gaG | gaC | 1 | 18 | AY.9.1 | 0.000084 |
S | 583 | E583D | gaG | gaC | 3 | 18 | B.1.221 | 0.000213 |
S | 583 | E583D | gaG | gaC | 11 | 18 | B.1.36.17 | 0.005435 |
S | 583 | E583D | gaG | gaC | 1 | 18 | P.1.14 | 0.000048 |
S | 583 | E583D | gaG | gaC | 3 | 17 | AY.119 | 0.000106 |
S | 583 | E583D | gaG | gaC | 3 | 17 | AY.120 | 0.000112 |
S | 583 | E583D | gaG | gaC | 2 | 15 | AY.9.2 | 0.000073 |
S | 583 | E583D | gaG | gaC | 7 | 15 | C.37 | 0.000812 |
S | 583 | E583D | gaG | gaC | 3 | 14 | AY.54 | 0.000286 |
S | 583 | E583D | gaG | gaC | 2 | 14 | AY.6 | 0.000082 |
S | 583 | E583D | gaG | gaC | 2 | 13 | AY.45 | 0.000243 |
S | 583 | E583D | gaG | gaC | 9 | 12 | P.1.15 | 0.002091 |
S | 583 | E583D | gaG | gaC | 4 | 11 | AY.23 | 0.000279 |
S | 583 | E583D | gaG | gaC | 4 | 11 | AY.3.1 | 0.000341 |
S | 583 | E583D | gaG | gaC | 4 | 11 | B.1.1.214 | 0.000222 |
S | 583 | E583D | gaG | gaC | 2 | 11 | B.1.596 | 0.000174 |
S | 583 | E583D | gaG | gaC | 2 | 10 | AY.117 | 0.000169 |
S | 583 | E583D | gaG | gaC | 4 | 10 | AY.98 | 0.000316 |
S | 583 | E583D | gaG | gaC | 2 | 9 | AY.46.6 | 0.000144 |
S | 583 | E583D | gaG | gaC | 1 | 9 | AY.9 | 0.000068 |
S | 583 | E583D | gaG | gaC | 6 | 9 | B.1.234 | 0.000792 |
S | 583 | E583D | gaG | gaC | 1 | 8 | AY.118 | 0.000063 |
S | 583 | E583D | gaG | gaC | 2 | 8 | AY.46 | 0.000208 |
S | 583 | E583D | gaG | gaC | 2 | 8 | B.1.1.519 | 0.000079 |
S | 583 | E583D | gaG | gaC | 1 | 7 | AY.120.1 | 0.000321 |
S | 583 | E583D | gaG | gaC | 1 | 7 | AY.99.2 | 0.000092 |
S | 583 | E583D | gaG | gaC | 2 | 7 | B.1.609 | 0.000959 |
S | 583 | E583D | gaG | gaC | 1 | 7 | C.36.3 | 0.000567 |
S | 583 | E583D | gaG | gaC | 3 | 7 | P.1.17 | 0.000485 |
S | 583 | E583D | gaG | gaC | 1 | 6 | B.1.177.86 | 0.000183 |
S | 583 | E583D | gaG | gaC | 2 | 6 | B.1.351.2 | 0.000605 |
S | 583 | E583D | gaG | gaC | 2 | 6 | B.1.525 | 0.000226 |
S | 583 | E583D | gaG | gaC | 3 | 6 | P.1.12 | 0.001452 |
S | 583 | E583D | gaG | gaC | 1 | 5 | AY.116 | 0.000287 |
S | 583 | E583D | gaG | gaC | 1 | 5 | AY.37 | 0.000316 |
S | 583 | E583D | gaG | gaC | 2 | 5 | AY.46.2 | 0.001271 |
S | 583 | E583D | gaG | gaC | 1 | 5 | AY.47 | 0.000031 |
S | 583 | E583D | gaG | gaC | 5 | 5 | B.1.1.63 | 0.001929 |
S | 583 | E583D | gaG | gaC | 2 | 4 | AY.13 | 0.000322 |
S | 583 | E583D | gaG | gaC | 3 | 4 | AY.35 | 0.000699 |
S | 583 | E583D | gaG | gaC | 1 | 4 | AY.51 | 0.000909 |
S | 583 | E583D | gaG | gaC | 1 | 4 | B.1.1.284 | 0.000107 |
S | 583 | E583D | gaG | gaC | 3 | 4 | B.1.306 | 0.017143 |
S | 583 | E583D | gaG | gaC | 2 | 4 | B.1.617.1 | 0.000258 |
S | 583 | E583D | gaG | gaC | 4 | 4 | R.1 | 0.00036 |
S | 583 | E583D | gaG | gaC | 2 | 3 | A.2.5 | 0.000998 |
S | 583 | E583D | gaG | gaC | 1 | 3 | AY.105 | 0.000643 |
S | 583 | E583D | gaG | gaC | 2 | 3 | AY.16.1 | 0.00094 |
S | 583 | E583D | gaG | gaC | 2 | 3 | AY.5.4 | 0.000553 |
S | 583 | E583D | gaG | gaC | 3 | 3 | B.1.1.266 | 0.036585 |
S | 583 | E583D | gaG | gaC | 1 | 3 | B.1.177.35 | 0.000691 |
S | 583 | E583D | gaG | gaC | 1 | 3 | B.1.177.7 | 0.000165 |
S | 583 | E583D | gaG | gaC | 2 | 3 | B.1.36 | 0.000292 |
S | 583 | E583D | gaG | gaC | 1 | 3 | B.1.366 | 0.004878 |
S | 583 | E583D | gaG | gaC | 2 | 3 | B.1.400 | 0.000858 |
S | 583 | E583D | gaG | gaC | 1 | 3 | B.1.436 | 0.001029 |
S | 583 | E583D | gaG | gaC | 2 | 3 | B.1.565 | 0.001621 |
S | 583 | E583D | gaG | gaC | 2 | 3 | B.1.628 | 0.000705 |
S | 583 | E583D | gaG | gaC | 3 | 3 | Q.3 | 0.000435 |
S | 583 | E583D | gaG | gaC | 1 | 2 | AY.5.3 | 0.000337 |
S | 583 | E583D | gaG | gaC | 1 | 2 | AY.55 | 0.000917 |
S | 583 | E583D | gaG | gaC | 2 | 2 | AY.61 | 0.00021 |
S | 583 | E583D | gaG | gaC | 1 | 2 | AY.99.1 | 0.001553 |
S | 583 | E583D | gaG | gaC | 1 | 2 | B.1.1.1 | 0.000327 |
S | 583 | E583D | gaG | gaC | 1 | 2 | B.1.110.3 | 0.000718 |
S | 583 | E583D | gaG | gaC | 1 | 2 | B.1.157 | 0.002985 |
S | 583 | E583D | gaG | gaC | 1 | 2 | B.1.177.57 | 0.000281 |
S | 583 | E583D | gaG | gaC | 1 | 2 | B.1.177.76 | 0.002494 |
S | 583 | E583D | gaG | gaC | 1 | 2 | B.1.236 | 0.002053 |
S | 583 | E583D | gaG | gaC | 2 | 2 | B.1.466.2 | 0.000782 |
S | 583 | E583D | gaG | gaC | 1 | 2 | P.2 | 0.000187 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AE.1 | 0.011364 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AP.1 | 0.001502 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.109 | 0.00074 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.120.2 | 0.001285 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.17 | 0.008197 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.30 | 0.000396 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.5.2 | 0.002463 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.59 | 0.00053 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.84 | 0.000437 |
S | 583 | E583D | gaG | gaC | 1 | 1 | AY.90 | 0.000684 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.1.348 | 0.000796 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.1.355 | 0.015385 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.1.376 | 0.005952 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.1.59 | 0.006494 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.12 | 0.008 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.160.26 | 0.002421 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.160.27 | 0.015152 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.237 | 0.004975 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.240 | 0.000216 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.258.3 | 0.001675 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.416 | 0.001269 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.427 | 0.00005 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.524 | 0.001406 |
S | 583 | E583D | gaG | gaC | 1 | 1 | B.1.582 | 0.000491 |
S | 583 | E583D | gaG | gaC | 1 | 1 | C.39 | 0.018868 |
S | 583 | E583D | gaG | gaC | 1 | 1 | W.3 | 0.005263 |
![]() |
![]() |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
|