CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 475 & Codon = gTc

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	475	A475V		nonsyn	gCc	gTc	1840	1828	0.993478	22985-22987

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	475	A475V	gCc	gTc	1828	1840	All	0.00035
S	475	A475V	gCc	gTc	1304	1308	B.1.1.7	0.001167
S	475	A475V	gCc	gTc	49	49	AY.4	0.000076
S	475	A475V	gCc	gTc	48	48	B.1.2	0.000423
S	475	A475V	gCc	gTc	33	34	B.1.258	0.002196
S	475	A475V	gCc	gTc	21	21	AY.120	0.000781
S	475	A475V	gCc	gTc	20	20	B.1.177	0.000263
S	475	A475V	gCc	gTc	19	19	AY.43	0.000084
S	475	A475V	gCc	gTc	19	19	B.1.617.2	0.000072
S	475	A475V	gCc	gTc	16	16	AY.3	0.000159
S	475	A475V	gCc	gTc	15	15	AY.33	0.001002
S	475	A475V	gCc	gTc	15	15	P.1	0.000236
S	475	A475V	gCc	gTc	14	14	B.1	0.000128
S	475	A475V	gCc	gTc	13	13	AY.25	0.000078
S	475	A475V	gCc	gTc	13	13	B.1.1	0.000236
S	475	A475V	gCc	gTc	10	10	AY.103	0.000062
S	475	A475V	gCc	gTc	10	10	Q.8	0.001649
S	475	A475V	gCc	gTc	8	9	AY.44	0.000049
S	475	A475V	gCc	gTc	7	7	AY.39	0.000173
S	475	A475V	gCc	gTc	7	7	B.1.405	0.08642
S	475	A475V	gCc	gTc	7	7	B.1.526	0.000165
S	475	A475V	gCc	gTc	6	6	AY.47	0.000187
S	475	A475V	gCc	gTc	6	6	B.1.1.519	0.000238
S	475	A475V	gCc	gTc	6	6	B.1.258.17	0.000624
S	475	A475V	gCc	gTc	6	6	B.1.638	0.315789
S	475	A475V	gCc	gTc	6	6	C.37	0.000696
S	475	A475V	gCc	gTc	6	6	P.1.14	0.000287
S	475	A475V	gCc	gTc	5	5	B.1.1.37	0.000964
S	475	A475V	gCc	gTc	4	4	AY.9	0.00027
S	475	A475V	gCc	gTc	4	4	B.1.351	0.000119
S	475	A475V	gCc	gTc	3	3	A	0.001161
S	475	A475V	gCc	gTc	3	3	AY.20	0.000117
S	475	A475V	gCc	gTc	3	3	AY.29	0.000047
S	475	A475V	gCc	gTc	3	3	AY.39.1	0.000119
S	475	A475V	gCc	gTc	3	3	B.1.1.39	0.001529
S	475	A475V	gCc	gTc	3	3	B.1.177.58	0.003995
S	475	A475V	gCc	gTc	3	3	B.1.36.8	0.003
S	475	A475V	gCc	gTc	3	3	B.1.429	0.000071
S	475	A475V	gCc	gTc	3	3	B.1.621	0.000266
S	475	A475V	gCc	gTc	3	3	B.1.628	0.001057
S	475	A475V	gCc	gTc	3	3	B.30	0.044118
S	475	A475V	gCc	gTc	2	2	AY.102	0.000053
S	475	A475V	gCc	gTc	2	2	AY.117	0.000169
S	475	A475V	gCc	gTc	2	2	AY.99.2	0.000184
S	475	A475V	gCc	gTc	2	2	B.1.1.63	0.000772
S	475	A475V	gCc	gTc	2	2	B.1.160.8	0.002577
S	475	A475V	gCc	gTc	2	2	B.1.177.60	0.000437
S	475	A475V	gCc	gTc	2	2	B.1.258.14	0.001961
S	475	A475V	gCc	gTc	2	2	B.1.36	0.000292
S	475	A475V	gCc	gTc	2	2	B.1.517	0.000854
S	475	A475V	gCc	gTc	2	2	B.1.525	0.000226
S	475	A475V	gCc	gTc	2	2	B.1.568	0.002222
S	475	A475V	gCc	gTc	2	2	B.1.596	0.000174
S	475	A475V	gCc	gTc	2	2	P.1.10	0.000539
S	475	A475V	gCc	gTc	2	2	P.2	0.000373
S	475	A475V	gCc	gTc	2	2	P.3	0.00319
S	475	A475V	gCc	gTc	1	1	A.23.1	0.000704
S	475	A475V	gCc	gTc	1	1	AY.100	0.000046
S	475	A475V	gCc	gTc	1	1	AY.105	0.000643
S	475	A475V	gCc	gTc	1	1	AY.113	0.000142
S	475	A475V	gCc	gTc	1	1	AY.118	0.000063
S	475	A475V	gCc	gTc	1	1	AY.119	0.000035
S	475	A475V	gCc	gTc	1	1	AY.121	0.000135
S	475	A475V	gCc	gTc	1	1	AY.34	0.000097
S	475	A475V	gCc	gTc	1	1	AY.4.2	0.000022
S	475	A475V	gCc	gTc	1	1	AY.4.2.1	0.000149
S	475	A475V	gCc	gTc	1	1	AY.4.5	0.000107
S	475	A475V	gCc	gTc	1	1	AY.40	0.000964
S	475	A475V	gCc	gTc	1	1	AY.45	0.000122
S	475	A475V	gCc	gTc	1	1	AY.46	0.000104
S	475	A475V	gCc	gTc	1	1	AY.5.3	0.000337
S	475	A475V	gCc	gTc	1	1	AY.74	0.000116
S	475	A475V	gCc	gTc	1	1	AY.84	0.000437
S	475	A475V	gCc	gTc	1	1	AY.88	0.000884
S	475	A475V	gCc	gTc	1	1	AY.99	0.001049
S	475	A475V	gCc	gTc	1	1	B.1.1.153	0.001095
S	475	A475V	gCc	gTc	1	1	B.1.1.176	0.000439
S	475	A475V	gCc	gTc	1	1	B.1.1.207	0.001182
S	475	A475V	gCc	gTc	1	1	B.1.1.214	0.000055
S	475	A475V	gCc	gTc	1	1	B.1.1.216	0.00089
S	475	A475V	gCc	gTc	1	1	B.1.1.222	0.000204
S	475	A475V	gCc	gTc	1	1	B.1.1.243	0.004082
S	475	A475V	gCc	gTc	1	1	B.1.1.28	0.000311
S	475	A475V	gCc	gTc	1	1	B.1.1.284	0.000107
S	475	A475V	gCc	gTc	1	1	B.1.1.303	0.002762
S	475	A475V	gCc	gTc	1	1	B.1.1.434	0.000349
S	475	A475V	gCc	gTc	1	1	B.1.1.56	0.017857
S	475	A475V	gCc	gTc	1	1	B.1.1.70	0.000341
S	475	A475V	gCc	gTc	1	1	B.1.1.71	0.006061
S	475	A475V	gCc	gTc	1	1	B.1.160	0.000031
S	475	A475V	gCc	gTc	1	1	B.1.177.17	0.000821
S	475	A475V	gCc	gTc	1	1	B.1.177.21	0.000076
S	475	A475V	gCc	gTc	1	1	B.1.177.49	0.037037
S	475	A475V	gCc	gTc	1	1	B.1.177.65	0.000665
S	475	A475V	gCc	gTc	1	1	B.1.177.7	0.000165
S	475	A475V	gCc	gTc	1	1	B.1.177.81	0.000189
S	475	A475V	gCc	gTc	1	1	B.1.221	0.000071
S	475	A475V	gCc	gTc	1	1	B.1.229	0.009709
S	475	A475V	gCc	gTc	1	1	B.1.240	0.000216
S	475	A475V	gCc	gTc	1	1	B.1.320	0.001245
S	475	A475V	gCc	gTc	1	1	B.1.351.5	0.0006
S	475	A475V	gCc	gTc	1	1	B.1.36.22	0.001208
S	475	A475V	gCc	gTc	1	1	B.1.36.29	0.000517
S	475	A475V	gCc	gTc	1	1	B.1.36.39	0.002217
S	475	A475V	gCc	gTc	1	1	B.1.369	0.000285
S	475	A475V	gCc	gTc	1	1	B.1.397	0.004854
S	475	A475V	gCc	gTc	1	1	B.1.427	0.00005
S	475	A475V	gCc	gTc	1	1	B.1.524	0.001406
S	475	A475V	gCc	gTc	1	1	B.1.575.1	0.002439
S	475	A475V	gCc	gTc	1	1	B.1.589	0.007576
S	475	A475V	gCc	gTc	1	1	B.1.617.3	0.002985
S	475	A475V	gCc	gTc	1	1	B.1.8	0.001972
S	475	A475V	gCc	gTc	1	1	C.1.2	0.004255
S	475	A475V	gCc	gTc	1	1	C.36.3	0.000567
S	475	A475V	gCc	gTc	1	1	D.3	0.005917
S	475	A475V	gCc	gTc	1	1	P.1.15	0.000232
S	475	A475V	gCc	gTc	1	1	P.1.17	0.000162
S	475	A475V	gCc	gTc	1	1	P.1.2	0.001156
S	475	A475V	gCc	gTc	1	1	P.1.4	0.000977
S	475	A475V	gCc	gTc	1	1	P.1.7	0.000319
S	475	A475V	gCc	gTc	1	1	P.7	0.004367
S	475	A475V	gCc	gTc	1	1	Q.1	0.000126
S	475	A475V	gCc	gTc	1	1	Q.4	0.000455
S	475	A475V	gCc	gTc	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.