CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 439 | N439K | nonsyn | aaC | aaA | 36642 | 36346 | 0.991922 | 22877-22879 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 439 | N439K | aaC | aaA | 36346 | 36642 | All | 0.006952 |
S | 439 | N439K | aaC | aaA | 14441 | 14441 | B.1.258 | 0.961004 |
S | 439 | N439K | aaC | aaA | 9241 | 9241 | B.1.258.17 | 0.960803 |
S | 439 | N439K | aaC | aaA | 2466 | 2466 | B.1.258.11 | 0.977408 |
S | 439 | N439K | aaC | aaA | 2358 | 2358 | B.1.466.2 | 0.922535 |
S | 439 | N439K | aaC | aaA | 1009 | 1009 | B.1.258.14 | 0.989216 |
S | 439 | N439K | aaC | aaA | 608 | 608 | B.1.258.16 | 0.99509 |
S | 439 | N439K | aaC | aaA | 578 | 578 | B.1.258.3 | 0.968174 |
S | 439 | N439K | aaC | aaA | 573 | 573 | B.1.222 | 0.969543 |
S | 439 | N439K | aaC | aaA | 515 | 515 | B.1.258.7 | 0.984704 |
S | 439 | N439K | aaC | aaA | 483 | 483 | AU.1 | 0.611392 |
S | 439 | N439K | aaC | aaA | 406 | 406 | AU.2 | 0.983051 |
S | 439 | N439K | aaC | aaA | 392 | 395 | B.1 | 0.003591 |
S | 439 | N439K | aaC | aaA | 383 | 383 | AU.3 | 0.808017 |
S | 439 | N439K | aaC | aaA | 375 | 375 | B.1.258.22 | 1 |
S | 439 | N439K | aaC | aaA | 273 | 273 | B.1.480 | 0.679104 |
S | 439 | N439K | aaC | aaA | 269 | 269 | B.1.258.4 | 0.927586 |
S | 439 | N439K | aaC | aaA | 214 | 214 | B.1.258.2 | 0.963964 |
S | 439 | N439K | aaC | aaA | 200 | 200 | B.1.258.9 | 1 |
S | 439 | N439K | aaC | aaA | 141 | 141 | B.1.258.19 | 1 |
S | 439 | N439K | aaC | aaA | 138 | 138 | B.1.466.1 | 0.992806 |
S | 439 | N439K | aaC | aaA | 129 | 129 | B.1.258.21 | 1 |
S | 439 | N439K | aaC | aaA | 124 | 124 | B.1.258.12 | 0.976378 |
S | 439 | N439K | aaC | aaA | 113 | 113 | B.1.258.5 | 0.991228 |
S | 439 | N439K | aaC | aaA | 93 | 93 | B.1.258.24 | 1 |
S | 439 | N439K | aaC | aaA | 79 | 92 | B.1.1.7 | 0.000071 |
S | 439 | N439K | aaC | aaA | 88 | 88 | B.1.258.10 | 1 |
S | 439 | N439K | aaC | aaA | 28 | 78 | B.1.1 | 0.000508 |
S | 439 | N439K | aaC | aaA | 63 | 63 | B.1.258.20 | 1 |
S | 439 | N439K | aaC | aaA | 61 | 61 | B.1.1.526 | 0.216312 |
S | 439 | N439K | aaC | aaA | 53 | 53 | B.1.258.15 | 1 |
S | 439 | N439K | aaC | aaA | 49 | 49 | B.1.258.6 | 0.960784 |
S | 439 | N439K | aaC | aaA | 33 | 33 | B.1.1.524 | 0.6875 |
S | 439 | N439K | aaC | aaA | 29 | 29 | B.1.160 | 0.000904 |
S | 439 | N439K | aaC | aaA | 29 | 29 | B.1.177 | 0.000382 |
S | 439 | N439K | aaC | aaA | 29 | 29 | B.1.258.23 | 0.690476 |
S | 439 | N439K | aaC | aaA | 28 | 28 | B.1.609 | 0.013423 |
S | 439 | N439K | aaC | aaA | 24 | 24 | G.1 | 1 |
S | 439 | N439K | aaC | aaA | 5 | 20 | AY.4 | 0.000008 |
S | 439 | N439K | aaC | aaA | 19 | 19 | B.1.462 | 0.137681 |
S | 439 | N439K | aaC | aaA | 12 | 12 | B.1.474 | 0.022814 |
S | 439 | N439K | aaC | aaA | 12 | 12 | B.1.628 | 0.004228 |
S | 439 | N439K | aaC | aaA | 10 | 10 | B.1.258.18 | 1 |
S | 439 | N439K | aaC | aaA | 9 | 9 | B.1.36 | 0.001313 |
S | 439 | N439K | aaC | aaA | 5 | 8 | B | 0.000639 |
S | 439 | N439K | aaC | aaA | 7 | 7 | A | 0.002709 |
S | 439 | N439K | aaC | aaA | 7 | 7 | B.1.177.73 | 0.003964 |
S | 439 | N439K | aaC | aaA | 7 | 7 | B.1.177.86 | 0.001284 |
S | 439 | N439K | aaC | aaA | 7 | 7 | B.1.632 | 0.04698 |
S | 439 | N439K | aaC | aaA | 7 | 7 | B.4.1 | 0.132075 |
S | 439 | N439K | aaC | aaA | 2 | 6 | B.1.1.519 | 0.000079 |
S | 439 | N439K | aaC | aaA | 6 | 6 | B.1.469 | 0.021661 |
S | 439 | N439K | aaC | aaA | 5 | 5 | B.1.1.216 | 0.004452 |
S | 439 | N439K | aaC | aaA | 5 | 5 | B.1.221 | 0.000355 |
S | 439 | N439K | aaC | aaA | 4 | 5 | C.37 | 0.000464 |
S | 439 | N439K | aaC | aaA | 4 | 4 | B.1.1.389 | 0.024242 |
S | 439 | N439K | aaC | aaA | 4 | 4 | B.1.36.29 | 0.002069 |
S | 439 | N439K | aaC | aaA | 4 | 4 | B.1.375 | 0.003279 |
S | 439 | N439K | aaC | aaA | 4 | 4 | B.1.590 | 0.018182 |
S | 439 | N439K | aaC | aaA | 4 | 4 | B.1.600 | 0.023392 |
S | 439 | N439K | aaC | aaA | 3 | 4 | B.1.617.2 | 0.000011 |
S | 439 | N439K | aaC | aaA | 4 | 4 | P.7 | 0.017467 |
S | 439 | N439K | aaC | aaA | 3 | 3 | AY.43 | 0.000013 |
S | 439 | N439K | aaC | aaA | 3 | 3 | B.1.177.6 | 0.00293 |
S | 439 | N439K | aaC | aaA | 3 | 3 | B.1.411 | 0.011111 |
S | 439 | N439K | aaC | aaA | 3 | 3 | B.1.460 | 0.053571 |
S | 439 | N439K | aaC | aaA | 1 | 2 | AY.102 | 0.000027 |
S | 439 | N439K | aaC | aaA | 2 | 2 | AY.23 | 0.000139 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.1.153 | 0.002191 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.1.39 | 0.001019 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.1.70 | 0.000682 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.177.44 | 0.001038 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.177.81 | 0.000379 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.36.17 | 0.000988 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.415.1 | 0.015152 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.432 | 0.022472 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.459 | 0.008163 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.533 | 0.019231 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.575 | 0.000607 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.596 | 0.000174 |
S | 439 | N439K | aaC | aaA | 2 | 2 | B.1.617.1 | 0.000258 |
S | 439 | N439K | aaC | aaA | 1 | 1 | A.19 | 0.009434 |
S | 439 | N439K | aaC | aaA | 1 | 1 | A.2 | 0.000662 |
S | 439 | N439K | aaC | aaA | 1 | 1 | A.2.5 | 0.000499 |
S | 439 | N439K | aaC | aaA | 1 | 1 | AY.103 | 0.000006 |
S | 439 | N439K | aaC | aaA | 1 | 1 | AY.20 | 0.000039 |
S | 439 | N439K | aaC | aaA | 1 | 1 | AY.24 | 0.000431 |
S | 439 | N439K | aaC | aaA | 1 | 1 | AY.34 | 0.000097 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.1.269 | 0.001353 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.1.379 | 0.03125 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.1.50 | 0.000679 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.1.51 | 0.001718 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.1.523 | 0.001563 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.1.528 | 0.004808 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.143 | 0.021277 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.157 | 0.002985 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.160.8 | 0.001289 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.177.31 | 0.011494 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.2 | 0.000009 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.214.2 | 0.0006 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.237 | 0.004975 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.247 | 0.014925 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.293 | 0.0125 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.362 | 0.001541 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.367 | 0.000792 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.380 | 0.006623 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.395 | 0.007042 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.406 | 0.006061 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.427 | 0.00005 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.473 | 0.019231 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.576 | 0.000907 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.599 | 0.00365 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.627 | 0.00202 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.631 | 0.003367 |
S | 439 | N439K | aaC | aaA | 1 | 1 | B.1.638 | 0.052632 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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