CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 370

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S370N370SnonsynaAtaGt465465122670-22672
S370N370NsynaaTaaC463463122670-22672
S370N370KnonsynaaTaaA2241260.562522670-22672
S370N370KnonsynaaTaaG224980.437522670-22672
S370N370deldelAAT---5555122670-22672
S370N370HnonsynAatCat5050122670-22672
S370N370DnonsynAatGat38370.97368422670-22672
S370N370DnonsynAaTGaC3810.026315822670-22672
S370N370InonsynaAtaTt99122670-22672
S370N370YnonsynAatTat66122670-22672
S370N370TnonsynaAtaCt55122670-22672
S370N370del1delaaTaa-320.66666722670-22672
S370N370del1delAat-at310.33333322670-22672
S370N370LnonsynAAtCTt22122670-22672
S370N370RnonsynAAtCGt22122670-22672
S370N370MnonsynaATaTG11122670-22672
S370N370QnonsynAaTCaG11122670-22672

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S370N370SaAtaGt465465All0.000089
S370N370NaaTaaC463463All0.000089
S370N370SaAtaGt257257AY.1030.001596
S370N370KaaTaaA126224All0.000024
S370N370KaaTaaG98224All0.000019
S370N370NaaTaaC9393B.1.1.70.000083
S370N370SaAtaGt9393B.1.6030.989362
S370N370KaaTaaG6870B.1.1.70.000061
S370N370KaaTaaA270B.1.1.70.000002
S370N370delAAT---5555All0.000011
S370N370HAatCat5050All0.00001
S370N370HAatCat4747B.1.1.70.000042
S370N370NaaTaaC4646AY.920.013215
S370N370DAatGat3738All0.000007
S370N370DAaTGaC138All0
S370N370SaAtaGt3636B.10.00033
S370N370KaaTaaA3334AY.40.000051
S370N370KaaTaaG134AY.40.000002
S370N370KaaTaaA3232B.1.10.000581
S370N370DAatGat2929B.1.1.70.000026
S370N370NaaTaaC2525B.1.617.20.000094
S370N370NaaTaaC2424AY.30.000239
S370N370KaaTaaA2323AY.4.50.002472
S370N370NaaTaaC1919AY.420.000764
S370N370NaaTaaC1818AY.4.20.00039
S370N370delAAT---1818B.1.1.70.000016
S370N370NaaTaaC1717AY.1030.000106
S370N370SaAtaGt1717AY.40.000026
S370N370SaAtaGt1616B.1.617.20.00006
S370N370NaaTaaC1515AY.200.000583
S370N370NaaTaaC1313AY.40.00002
S370N370NaaTaaC1212B.1.1600.000374
S370N370NaaTaaC1212B.1.20.000106
S370N370NaaTaaC1010AY.390.000247
S370N370NaaTaaC1010AY.440.000061
S370N370IaAtaTt99All0.000002
S370N370NaaTaaC99B.1.10.000163
S370N370NaaTaaC88AY.250.000048
S370N370NaaTaaC88AY.430.000035
S370N370NaaTaaC88B.1.1.3170.003294
S370N370NaaTaaC88B.1.1.500.005431
S370N370YAatTat66All0.000001
S370N370SaAtaGt66B.1.1.70.000005
S370N370NaaTaaC66B.1.5960.000523
S370N370TaAtaCt55All0.000001
S370N370SaAtaGt55AY.290.000079
S370N370NaaTaaC55AY.330.000334
S370N370KaaTaaG45AY.430.000018
S370N370KaaTaaA15AY.430.000004
S370N370KaaTaaA55AY.90.000338
S370N370delAAT---55B.10.000046
S370N370SaAtaGt55B.1.177.540.003032
S370N370delAAT---55B.1.2580.000333
S370N370NaaTaaC55B.1.3490.003574
S370N370NaaTaaC44AY.100.00212
S370N370NaaTaaC44AY.1020.000106
S370N370SaAtaGt44AY.330.000267
S370N370NaaTaaC44AY.460.000416
S370N370KaaTaaA44AY.80.002424
S370N370NaaTaaC44B.10.000037
S370N370KaaTaaG44B.1.1.2840.00043
S370N370NaaTaaC44B.1.1.3980.012903
S370N370KaaTaaG44B.1.36.170.001976
S370N370NaaTaaC44B.1.5260.000094
S370N370NaaTaaC44B.1.6090.001918
S370N370del1aaTaa-23All0
S370N370del1Aat-at13All0
S370N370NaaTaaC33AY.1000.000138
S370N370NaaTaaC33AY.1190.000106
S370N370NaaTaaC33AY.290.000047
S370N370NaaTaaC33AY.980.000237
S370N370NaaTaaC33B.1.1.2540.033708
S370N370NaaTaaC33B.1.1.5190.000119
S370N370SaAtaGt33B.1.20.000026
S370N370KaaTaaG33B.1.4270.000151
S370N370KaaTaaA33B.1.4290.000071
S370N370NaaTaaC33B.1.4510.02459
S370N370delAAT---33B.1.617.20.000011
S370N370KaaTaaA23B.1.617.20.000008
S370N370KaaTaaG13B.1.617.20.000004
S370N370NaaTaaC33B.1.6210.000266
S370N370HAatCat220.111111
S370N370LAAtCTt220.111111
S370N370RAAtCGt220.111111
S370N370IaAtaTt220.111111
S370N370LAAtCTt22All0
S370N370RAAtCGt22All0
S370N370KaaTaaA22AY.1200.000074
S370N370delAAT---22AY.350.000466
S370N370DAatGat22AY.430.000009
S370N370SaAtaGt22AY.440.000012
S370N370TaAtaCt22AY.440.000012
S370N370SaAtaGt22AY.470.000062
S370N370KaaTaaA22AY.580.001815
S370N370SaAtaGt22AY.710.00095
S370N370KaaTaaA22B.10.000018
S370N370KaaTaaG22B.1.1580.047619
S370N370KaaTaaG12B.1.1770.000013
S370N370KaaTaaA12B.1.1770.000013
S370N370KaaTaaG22B.1.177.40.000422
S370N370DAatGat22B.1.177.520.003515
S370N370delAAT---22B.1.20.000018
S370N370KaaTaaA12B.1.20.000009
S370N370KaaTaaG12B.1.20.000009
S370N370KaaTaaG22B.1.2360.004107
S370N370NaaTaaC22B.1.4290.000047
S370N370NaaTaaC22B.1.4700.002809
S370N370YAatTat22B.1.617.20.000008
S370N370NaaTaaC22C.370.000232
S370N370SaAtaGt22C.370.000232
S370N370SaAtaGt22P.10.000032
S370N370NaaTaaC22P.1.150.000465
S370N370DAaTGaC12P.20.000187
S370N370DAatGat12P.20.000187
S370N370NaaTaaC11A0.000387
S370N370MaATaTG11All0
S370N370QAaTCaG11All0
S370N370SaAtaGt11AY.1020.000027
S370N370KaaTaaA11AY.1030.000006
S370N370delAAT---11AY.1070.000466
S370N370NaaTaaC11AY.1090.00074
S370N370NaaTaaC11AY.1130.000142
S370N370IaAtaTt11AY.1170.000085
S370N370DAatGat11AY.1180.000063
S370N370NaaTaaC11AY.1200.000037
S370N370NaaTaaC11AY.160.00038
S370N370KaaTaaA11AY.170.008197
S370N370delAAT---11AY.230.00007
S370N370NaaTaaC11AY.23.10.000417
S370N370DAatGat11AY.250.000006
S370N370SaAtaGt11AY.250.000006
S370N370IaAtaTt11AY.250.000006
S370N370KaaTaaA11AY.260.000028
S370N370NaaTaaC11AY.270.000065
S370N370YAatTat11AY.30.00001
S370N370IaAtaTt11AY.30.00001
S370N370NaaTaaC11AY.3.10.000085
S370N370KaaTaaG11AY.320.000532
S370N370KaaTaaA11AY.330.000067
S370N370TaAtaCt11AY.360.000148
S370N370IaAtaTt11AY.40.000002
S370N370TaAtaCt11AY.40.000002
S370N370SaAtaGt11AY.4.20.000022
S370N370delAAT---11AY.4.50.000107
S370N370SaAtaGt11AY.4.50.000107
S370N370del1aaTaa-11AY.430.000004
S370N370SaAtaGt11AY.430.000004
S370N370delAAT---11AY.430.000004
S370N370KaaTaaG11AY.440.000006
S370N370NaaTaaC11AY.450.000122
S370N370SaAtaGt11AY.450.000122
S370N370delAAT---11AY.460.000104
S370N370SaAtaGt11AY.46.60.000072
S370N370NaaTaaC11AY.470.000031
S370N370YAatTat11AY.50.000021
S370N370NaaTaaC11AY.60.000041
S370N370NaaTaaC11AY.610.000105
S370N370delAAT---11AY.720.001361
S370N370NaaTaaC11AY.740.000116
S370N370delAAT---11AY.75.10.00018
S370N370NaaTaaC11AY.790.001211
S370N370KaaTaaA11AY.870.000833
S370N370NaaTaaC11AY.90.000068
S370N370delAAT---11AY.90.000068
S370N370del1Aat-at11B.10.000009
S370N370MaATaTG11B.10.000009
S370N370delAAT---11B.1.10.000018
S370N370SaAtaGt11B.1.10.000018
S370N370YAatTat11B.1.1.10.000327
S370N370delAAT---11B.1.1.10.000327
S370N370NaaTaaC11B.1.1.2200.001859
S370N370delAAT---11B.1.1.2210.010101
S370N370SaAtaGt11B.1.1.2650.003155
S370N370NaaTaaC11B.1.1.2720.005208
S370N370NaaTaaC11B.1.1.280.000311
S370N370delAAT---11B.1.1.3150.008475
S370N370SaAtaGt11B.1.1.3160.000925
S370N370SaAtaGt11B.1.1.3530.020833
S370N370NaaTaaC11B.1.1.3690.000446
S370N370KaaTaaA11B.1.1.5190.00004
S370N370delAAT---11B.1.1.5210.005348
S370N370del1aaTaa-11B.1.1.70.000001
S370N370KaaTaaA11B.1.1280.000635
S370N370delAAT---11B.1.1400.018868
S370N370IaAtaTt11B.1.160.220.006757
S370N370KaaTaaA11B.1.160.320.004292
S370N370delAAT---11B.1.1770.000013
S370N370delAAT---11B.1.177.180.00116
S370N370TaAtaCt11B.1.177.210.000076
S370N370KaaTaaG11B.1.177.440.000519
S370N370delAAT---11B.1.177.500.004695
S370N370KaaTaaG11B.1.2210.000071
S370N370NaaTaaC11B.1.2360.002053
S370N370SaAtaGt11B.1.2390.001221
S370N370delAAT---11B.1.2420.018868
S370N370NaaTaaC11B.1.2430.00007
S370N370NaaTaaC11B.1.2580.000067
S370N370DAatGat11B.1.2580.000067
S370N370NaaTaaC11B.1.258.170.000104
S370N370NaaTaaC11B.1.3510.00003
S370N370KaaTaaA11B.1.36.180.00042
S370N370NaaTaaC11B.1.36.290.000517
S370N370delAAT---11B.1.4090.000781
S370N370NaaTaaC11B.1.4590.004082
S370N370IaAtaTt11B.1.5330.009615
S370N370NaaTaaC11B.1.5970.00463
S370N370KaaTaaA11B.1.5990.00365
S370N370IaAtaTt11B.1.617.20.000004
S370N370delAAT---11B.1.6200.000946
S370N370KaaTaaA11B.1.6210.000089
S370N370KaaTaaG11B.1.910.002075
S370N370QAaTCaG11B.1.910.002075
S370N370HAatCat11B.1.910.002075
S370N370KaaTaaA11B.6.60.000889
S370N370NaaTaaC11C.330.058824
S370N370NaaTaaC11D.20.000075
S370N370NaaTaaC11N.90.005952
S370N370SaAtaGt11P.1.140.000048
S370N370KaaTaaA11P.20.000187
S370N370NaaTaaC11P.20.000187
S370N370NaaTaaC11P.70.004367
S370N370YAatTat11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.