CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 26 | P26L | nonsyn | cCt | cTt | 3957 | 3951 | 0.998484 | 21638-21640 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 26 | P26L | cCt | cTt | 3951 | 3957 | All | 0.000756 |
S | 26 | P26L | cCt | cTt | 636 | 637 | AY.103 | 0.003949 |
S | 26 | P26L | cCt | cTt | 444 | 444 | B.1.1.7 | 0.000397 |
S | 26 | P26L | cCt | cTt | 319 | 319 | AY.4 | 0.000496 |
S | 26 | P26L | cCt | cTt | 276 | 276 | B.1.1.372 | 0.190083 |
S | 26 | P26L | cCt | cTt | 215 | 215 | B.1.258.17 | 0.022354 |
S | 26 | P26L | cCt | cTt | 158 | 158 | B.1.351 | 0.004697 |
S | 26 | P26L | cCt | cTt | 156 | 157 | B.1.617.2 | 0.000587 |
S | 26 | P26L | cCt | cTt | 136 | 136 | B.1.544 | 0.819277 |
S | 26 | P26L | cCt | cTt | 101 | 101 | B.1.2 | 0.000889 |
S | 26 | P26L | cCt | cTt | 84 | 84 | B.1.1 | 0.001524 |
S | 26 | P26L | cCt | cTt | 82 | 82 | AY.43 | 0.000363 |
S | 26 | P26L | cCt | cTt | 75 | 75 | B.1.429 | 0.001765 |
S | 26 | P26L | cCt | cTt | 67 | 67 | B.1.265 | 0.085133 |
S | 26 | P26L | cCt | cTt | 63 | 63 | AY.33 | 0.004207 |
S | 26 | P26L | cCt | cTt | 62 | 62 | AY.23 | 0.004324 |
S | 26 | P26L | cCt | cTt | 60 | 60 | AY.3 | 0.000597 |
S | 26 | P26L | cCt | cTt | 59 | 59 | AY.44 | 0.000359 |
S | 26 | P26L | cCt | cTt | 59 | 59 | B.1 | 0.00054 |
S | 26 | P26L | cCt | cTt | 52 | 52 | B.1.177 | 0.000685 |
S | 26 | P26L | cCt | cTt | 41 | 41 | B.1.637 | 0.002996 |
S | 26 | P26L | cCt | cTt | 39 | 39 | AY.5 | 0.000805 |
S | 26 | P26L | cCt | cTt | 38 | 38 | AY.25 | 0.000229 |
S | 26 | P26L | cCt | cTt | 38 | 38 | B.1.241 | 0.030844 |
S | 26 | P26L | cCt | cTt | 28 | 28 | B.1.577 | 0.019244 |
S | 26 | P26L | cCt | cTt | 26 | 26 | AY.119 | 0.000918 |
S | 26 | P26L | cCt | cTt | 26 | 26 | AY.46.4 | 0.004277 |
S | 26 | P26L | cCt | cTt | 25 | 25 | AY.20 | 0.000972 |
S | 26 | P26L | cCt | cTt | 24 | 24 | P.2 | 0.004479 |
S | 26 | P26L | cCt | cTt | 22 | 22 | P.1 | 0.000347 |
S | 26 | P26L | cCt | cTt | 19 | 19 | AY.14 | 0.001672 |
S | 26 | P26L | cCt | cTt | 19 | 19 | AY.7.2 | 0.010626 |
S | 26 | P26L | cCt | cTt | 18 | 18 | AY.121 | 0.002436 |
S | 26 | P26L | cCt | cTt | 17 | 17 | B.1.160 | 0.00053 |
S | 26 | P26L | cCt | cTt | 15 | 15 | Q.3 | 0.002175 |
S | 26 | P26L | cCt | cTt | 14 | 14 | AY.39 | 0.000346 |
S | 26 | P26L | cCt | cTt | 13 | 13 | B.1.221 | 0.000923 |
S | 26 | P26L | cCt | cTt | 13 | 13 | B.1.258 | 0.000865 |
S | 26 | P26L | cCt | cTt | 12 | 12 | AY.106 | 0.004019 |
S | 26 | P26L | cCt | cTt | 12 | 12 | AY.118 | 0.000752 |
S | 26 | P26L | cCt | cTt | 12 | 12 | AY.120 | 0.000446 |
S | 26 | P26L | cCt | cTt | 12 | 12 | AY.26 | 0.00034 |
S | 26 | P26L | cCt | cTt | 10 | 10 | B.1.177.75 | 0.010406 |
S | 26 | P26L | cCt | cTt | 10 | 10 | B.1.243 | 0.000696 |
S | 26 | P26L | cCt | cTt | 10 | 10 | B.1.526 | 0.000235 |
S | 26 | P26L | cCt | cTt | 9 | 9 | AY.100 | 0.000414 |
S | 26 | P26L | cCt | cTt | 9 | 9 | AY.102 | 0.000239 |
S | 26 | P26L | cCt | cTt | 8 | 8 | AY.117 | 0.000676 |
S | 26 | P26L | cCt | cTt | 8 | 8 | B.1.1.519 | 0.000318 |
S | 26 | P26L | cCt | cTt | 8 | 8 | B.1.596 | 0.000697 |
S | 26 | P26L | cCt | cTt | 7 | 7 | AY.61 | 0.000733 |
S | 26 | P26L | cCt | cTt | 7 | 7 | B.40 | 0.00255 |
S | 26 | P26L | cCt | cTt | 2 | 6 | 0.111111 | |
S | 26 | P26L | cCt | cTt | 6 | 6 | AY.47 | 0.000187 |
S | 26 | P26L | cCt | cTt | 6 | 6 | B.1.427 | 0.000303 |
S | 26 | P26L | cCt | cTt | 6 | 6 | B.1.524 | 0.008439 |
S | 26 | P26L | cCt | cTt | 6 | 6 | C.37 | 0.000696 |
S | 26 | P26L | cCt | cTt | 5 | 5 | AY.24 | 0.002155 |
S | 26 | P26L | cCt | cTt | 5 | 5 | AY.34.1 | 0.00255 |
S | 26 | P26L | cCt | cTt | 5 | 5 | AY.98 | 0.000395 |
S | 26 | P26L | cCt | cTt | 5 | 5 | B.1.399 | 0.009671 |
S | 26 | P26L | cCt | cTt | 5 | 5 | B.1.466.2 | 0.001956 |
S | 26 | P26L | cCt | cTt | 4 | 4 | A.21 | 0.01108 |
S | 26 | P26L | cCt | cTt | 4 | 4 | AY.29 | 0.000063 |
S | 26 | P26L | cCt | cTt | 4 | 4 | AY.39.1 | 0.000158 |
S | 26 | P26L | cCt | cTt | 4 | 4 | AY.4.2 | 0.000087 |
S | 26 | P26L | cCt | cTt | 4 | 4 | AY.71 | 0.0019 |
S | 26 | P26L | cCt | cTt | 4 | 4 | B.1.159 | 0.04878 |
S | 26 | P26L | cCt | cTt | 4 | 4 | B.1.177.4 | 0.000844 |
S | 26 | P26L | cCt | cTt | 4 | 4 | B.1.177.80 | 0.007648 |
S | 26 | P26L | cCt | cTt | 4 | 4 | B.1.525 | 0.000453 |
S | 26 | P26L | cCt | cTt | 4 | 4 | B.1.621 | 0.000354 |
S | 26 | P26L | cCt | cTt | 4 | 4 | Q.1 | 0.000505 |
S | 26 | P26L | cCt | cTt | 4 | 4 | R.1 | 0.00036 |
S | 26 | P26L | cCt | cTt | 3 | 3 | A.2.5 | 0.001497 |
S | 26 | P26L | cCt | cTt | 3 | 3 | AY.27 | 0.000194 |
S | 26 | P26L | cCt | cTt | 3 | 3 | AY.35 | 0.000699 |
S | 26 | P26L | cCt | cTt | 3 | 3 | AY.45 | 0.000365 |
S | 26 | P26L | cCt | cTt | 3 | 3 | AY.46 | 0.000312 |
S | 26 | P26L | cCt | cTt | 3 | 3 | AY.52 | 0.002443 |
S | 26 | P26L | cCt | cTt | 3 | 3 | AY.68 | 0.000821 |
S | 26 | P26L | cCt | cTt | 3 | 3 | B.1.1.306 | 0.001315 |
S | 26 | P26L | cCt | cTt | 3 | 3 | B.1.177.81 | 0.000568 |
S | 26 | P26L | cCt | cTt | 3 | 3 | B.1.36 | 0.000438 |
S | 26 | P26L | cCt | cTt | 3 | 3 | B.1.369 | 0.000856 |
S | 26 | P26L | cCt | cTt | 3 | 3 | N.6 | 0.021277 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.110 | 0.000225 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.22 | 0.004184 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.36 | 0.000296 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.4.4 | 0.000818 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.4.5 | 0.000215 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.40 | 0.001929 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.5.3 | 0.000675 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.5.4 | 0.000553 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.54 | 0.000191 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.55 | 0.001835 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.7.1 | 0.000225 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.70 | 0.000417 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.75.1 | 0.000361 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.9.1 | 0.000167 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.93 | 0.000546 |
S | 26 | P26L | cCt | cTt | 2 | 2 | AY.99.2 | 0.000184 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.1.214 | 0.000111 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.1.25 | 0.001137 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.1.39 | 0.001019 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.240 | 0.000431 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.348 | 0.036364 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.36.29 | 0.001035 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.400 | 0.000858 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.471 | 0.005464 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.565 | 0.001621 |
S | 26 | P26L | cCt | cTt | 2 | 2 | B.1.575 | 0.000607 |
S | 26 | P26L | cCt | cTt | 2 | 2 | C.1 | 0.004785 |
S | 26 | P26L | cCt | cTt | 2 | 2 | C.14 | 0.008658 |
S | 26 | P26L | cCt | cTt | 2 | 2 | Q.8 | 0.00033 |
S | 26 | P26L | cCt | cTt | 1 | 1 | A.2 | 0.000662 |
S | 26 | P26L | cCt | cTt | 1 | 1 | A.23.1 | 0.000704 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AA.1 | 0.007246 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.116 | 0.000287 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.12 | 0.000316 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.120.2.1 | 0.000498 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.13 | 0.000161 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.16 | 0.00038 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.23.1 | 0.000417 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.30 | 0.000396 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.4.2.1 | 0.000149 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.41 | 0.000294 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.42 | 0.00004 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.46.5 | 0.000198 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.46.6 | 0.000072 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.57 | 0.000656 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.6 | 0.000041 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.63 | 0.000387 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.67 | 0.000464 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.69 | 0.000187 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.75 | 0.000056 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.79 | 0.001211 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.80 | 0.001129 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.84 | 0.000437 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.9 | 0.000068 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.9.2 | 0.000037 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.92 | 0.000287 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.94 | 0.000443 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.98.1 | 0.000048 |
S | 26 | P26L | cCt | cTt | 1 | 1 | AY.99 | 0.001049 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.176 | 0.000439 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.222 | 0.000204 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.241 | 0.00207 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.28 | 0.000311 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.284 | 0.000107 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.302 | 0.002075 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.312 | 0.001912 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.318 | 0.000302 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.325 | 0.025641 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.328 | 0.016949 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.33 | 0.000421 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.348 | 0.000796 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.377 | 0.001381 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.431 | 0.016129 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.432 | 0.001266 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.50 | 0.000679 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.523 | 0.001563 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.1.59 | 0.006494 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.118 | 0.006711 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.146 | 0.004237 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.160.16 | 0.000929 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.177.15 | 0.000631 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.177.21 | 0.000076 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.177.51 | 0.004566 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.210 | 0.002132 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.214.2 | 0.0006 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.234 | 0.000132 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.236 | 0.002053 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.239 | 0.001221 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.36.17 | 0.000494 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.36.27 | 0.000763 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.404 | 0.001302 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.416 | 0.001269 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.426 | 0.001009 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.433 | 0.003195 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.438.1 | 0.000107 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.468 | 0.005714 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.517 | 0.000427 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.521 | 0.004975 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.564 | 0.000426 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.590 | 0.004545 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.591 | 0.010638 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.605 | 0.005952 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.617.1 | 0.000129 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.619 | 0.000871 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.623 | 0.000536 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.630 | 0.005236 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.631 | 0.003367 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.9.5 | 0.005682 |
S | 26 | P26L | cCt | cTt | 1 | 1 | B.1.93 | 0.000934 |
S | 26 | P26L | cCt | cTt | 1 | 1 | C.36.3 | 0.000567 |
S | 26 | P26L | cCt | cTt | 1 | 1 | C.38 | 0.008065 |
S | 26 | P26L | cCt | cTt | 1 | 1 | D.2 | 0.000075 |
S | 26 | P26L | cCt | cTt | 1 | 1 | L.3 | 0.003546 |
S | 26 | P26L | cCt | cTt | 1 | 1 | P.1.7 | 0.000319 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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