CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 251

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
S251P251LnonsyncCtcTt25462254540.99968622313-22315
S251P251LnonsynCCTTTA2546270.00027491922313-22315
S251P251LnonsyncCTcTA2546210.000039274222313-22315
S251P251deldelCCT---77787778122313-22315
S251P251SnonsynCctTct121312110.99835122313-22315
S251P251SnonsynCcTTcA121320.001648822313-22315
S251P251HnonsyncCtcAt9697300.75335422313-22315
S251P251HnonsyncCTcAC9692390.24664622313-22315
S251P251PsynccTccC3502520.7222313-22315
S251P251PsynccTccA350780.22285722313-22315
S251P251PsynccTccG350200.057142922313-22315
S251P251TnonsynCctAct318318122313-22315
S251P251del1delCct-ct87850.97701222313-22315
S251P251del1delCCT-NN8710.011494322313-22315
S251P251del1delccTcc-8710.011494322313-22315
S251P251RnonsyncCtcGt14130.92857122313-22315
S251P251RnonsyncCTcGA1410.071428622313-22315
S251P251FnonsynCCtTTt66122313-22315
S251P251XnonsynCCTTGA55122313-22315
S251P251del2delCCt--t310.33333322313-22315
S251P251del2delcCTc--310.33333322313-22315
S251P251del2delCCT--N310.33333322313-22315
S251P251AnonsynCctGct11122313-22315
S251P251NnonsynCCtAAt11122313-22315
S251P251CnonsynCCtTGt11122313-22315

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
S251P251LcCtcTt2545425462All0.004868
S251P251LCCTTTA725462All0.000001
S251P251LcCTcTA125462All0
S251P251LcCtcTt1971819718AY.98.10.954959
S251P251delCCT---77787778All0.001488
S251P251delCCT---73977397C.370.858519
S251P251LcCtcTt24062406B.1.617.20.00906
S251P251LcCtcTt15591559AY.980.123153
S251P251SCctTct12111213All0.000232
S251P251SCcTTcA21213All0
S251P251HcCtcAt730969All0.00014
S251P251HcCTcAC239969All0.000046
S251P251SCctTct863863B.1.20.007599
S251P251LcCtcTt850850AY.75.10.153264
S251P251PccTccC252350All0.000048
S251P251PccTccA78350All0.000015
S251P251PccTccG20350All0.000004
S251P251TCctAct318318All0.000061
S251P251delCCT---267267C.37.10.698953
S251P251HcCTcAC237248AY.430.00105
S251P251HcCtcAt11248AY.430.000049
S251P251LcCtcTt220220B.1.1.70.000197
S251P251LcCtcTt211211AY.30.002099
S251P251HcCtcAt175175B.1.2390.213675
S251P251LcCtcTt110110AY.40.000171
S251P251LcCtcTt106106AB.10.868852
S251P251TCctAct103103B.1.1.70.000092
S251P251del1Cct-ct8587All0.000016
S251P251del1CCT-NN187All0
S251P251del1ccTcc-187All0
S251P251HcCtcAt8787P.10.001371
S251P251PccTccC8285B.1.1.70.000073
S251P251PccTccA385B.1.1.70.000003
S251P251SCctTct8484AY.1170.007099
S251P251TCctAct7373AY.200.002837
S251P251del1Cct-ct6666B.1.1.70.000059
S251P251HcCtcAt6565B.1.1.70.000058
S251P251SCctTct5858B.1.1.70.000052
S251P251HcCtcAt4141B.1.1.5190.001628
S251P251PccTccC3939D.20.002927
S251P251PccTccA3737B.1.2790.019004
S251P251PccTccC3233AY.40.00005
S251P251PccTccA133AY.40.000002
S251P251HcCtcAt3131AY.40.000048
S251P251TCctAct3131AY.40.000048
S251P251HcCtcAt2929B.1.617.20.000109
S251P251LcCtcTt2828AY.430.000124
S251P251HcCtcAt2828AY.440.00017
S251P251HcCtcAt2626B.1.2430.001809
S251P251SCctTct2525AY.40.000039
S251P251PccTccC2525B.1.438.10.002682
S251P251HcCtcAt2424AY.390.000593
S251P251HcCtcAt2323B.1.1770.000303
S251P251HcCtcAt2222B.10.000202
S251P251SCctTct2222B.1.2210.001563
S251P251SCctTct1919B.10.000174
S251P251TCctAct1717B.1.617.20.000064
S251P251delCCT---1717P.1.150.00395
S251P251PccTccC1516AY.250.00009
S251P251PccTccA116AY.250.000006
S251P251LcCtcTt1616AY.440.000097
S251P251LcCtcTt1616B.10.000147
S251P251SCctTct1515AY.1030.000093
S251P251PccTccG1515AY.600.014071
S251P251delCCT---1515B.1.1.70.000013
S251P251TCctAct1515B.1.351.50.008993
S251P251RcCtcGt1314All0.000002
S251P251RcCTcGA114All0
S251P251LcCtcTt1414AY.1030.000087
S251P251HcCtcAt1414AY.1030.000087
S251P251LcCtcTt1414B.1.1.2491
S251P251TCctAct1313AY.430.000058
S251P251PccTccA1313B.1.160.280.038012
S251P251SCctTct1212B.1.2580.000799
S251P251PccTccC911B.10.000082
S251P251PccTccA211B.10.000018
S251P251SCctTct1111B.1.4690.039711
S251P251HcCtcAt99AY.1180.000564
S251P251delCCT---99B.10.000082
S251P251SCctTct99B.1.617.20.000034
S251P251LCCTTTA79C.370.000812
S251P251LcCtcTt19C.370.000116
S251P251LcCTcTA19C.370.000116
S251P251HcCtcAt77AY.1110.001282
S251P251HcCtcAt77AY.30.00007
S251P251PccTccA67AY.440.000037
S251P251PccTccC17AY.440.000006
S251P251HcCtcAt77AY.50.000145
S251P251LcCtcTt77AY.750.000392
S251P251LcCtcTt77Q.70.007778
S251P251HcCtcAt66AB.10.04918
S251P251FCCtTTt66All0.000001
S251P251TCctAct66AY.250.000036
S251P251LcCtcTt66AY.250.000036
S251P251LcCtcTt66AY.340.000582
S251P251LcCtcTt66AY.390.000148
S251P251delCCT---66AY.430.000027
S251P251LcCtcTt66AY.46.60.000433
S251P251TCctAct66B.10.000055
S251P251LcCtcTt66B.1.1.2800.018519
S251P251PccTccC46B.1.1770.000053
S251P251PccTccA26B.1.1770.000026
S251P251TCctAct66B.1.2210.000426
S251P251SCctTct66B.1.5260.000141
S251P251SCctTct66B.1.5960.000523
S251P251delCCT---66B.1.617.20.000023
S251P251HcCtcAt66B.1.6210.000531
S251P251delCCT---66P.10.000095
S251P251XCCTTGA55All0.000001
S251P251LcCtcTt55AY.1200.000186
S251P251SCctTct55AY.250.00003
S251P251LcCtcTt55AY.260.000142
S251P251HcCtcAt55AY.3.10.000426
S251P251TCctAct55AY.470.000156
S251P251HcCtcAt55B.1.10.000091
S251P251HcCtcAt55B.1.1.3180.001509
S251P251PccTccC55B.1.177.120.000758
S251P251LcCtcTt55B.1.20.000044
S251P251HcCtcAt55B.1.20.000044
S251P251delCCT---55B.1.6210.000443
S251P251XCCTTGA55C.370.00058
S251P251del1Cct-ct440.222222
S251P251LcCtcTt44AY.1100.000451
S251P251TCctAct44AY.1190.000141
S251P251HcCtcAt44AY.230.000279
S251P251delCCT---44AY.250.000024
S251P251PccTccC44AY.290.000063
S251P251delCCT---44AY.290.000063
S251P251RcCtcGt44AY.30.00004
S251P251LcCtcTt44AY.34.10.00204
S251P251HcCtcAt34AY.420.000121
S251P251HcCTcAC14AY.420.00004
S251P251PccTccC44AY.430.000018
S251P251LcCtcTt44AY.46.50.000794
S251P251HcCtcAt44AY.470.000124
S251P251SCctTct44B.1.10.000073
S251P251SCctTct44B.1.1.5190.000159
S251P251TCctAct44B.1.4290.000094
S251P251LcCtcTt44B.1.6370.000292
S251P251del2CCT--N13All0
S251P251del2cCTc--13All0
S251P251del2CCt--t13All0
S251P251HcCtcAt33AY.1020.00008
S251P251delCCT---33AY.1020.00008
S251P251TCctAct33AY.1020.00008
S251P251TCctAct33AY.1030.000019
S251P251SCctTct33AY.1110.000549
S251P251HcCtcAt33AY.1130.000427
S251P251HcCtcAt33AY.140.000264
S251P251TCctAct33AY.30.00003
S251P251SCctTct33AY.30.00003
S251P251LcCtcTt33AY.3.10.000256
S251P251HcCtcAt33AY.320.001597
S251P251TCctAct33AY.340.000291
S251P251HcCtcAt33AY.4.20.000065
S251P251SCctTct33AY.440.000018
S251P251LcCtcTt33AY.460.000312
S251P251SCctTct33AY.470.000093
S251P251LcCtcTt33AY.5.40.00083
S251P251LcCtcTt33AY.540.000286
S251P251PccTccC33AY.790.003632
S251P251LcCtcTt33AY.840.001312
S251P251LcCtcTt33AY.9.20.00011
S251P251PccTccC33AY.9.20.00011
S251P251HcCtcAt33AY.99.20.000276
S251P251PccTccC33B.1.1.280.000934
S251P251delCCT---33B.1.1770.00004
S251P251del1Cct-ct33B.1.177.820.001432
S251P251PccTccC33B.1.20.000026
S251P251LcCtcTt33B.1.2430.000209
S251P251LcCtcTt33B.1.3510.000089
S251P251SCctTct33B.1.4290.000071
S251P251HcCtcAt33B.1.5250.000339
S251P251HcCtcAt33B.1.5260.000071
S251P251SCctTct33B.1.5710.029126
S251P251SCcTTcA23C.370.000232
S251P251SCctTct13C.370.000116
S251P251SCctTct33P.10.000047
S251P251PccTccC23P.10.000032
S251P251PccTccA13P.10.000016
S251P251HcCtcAt33Q.80.000495
S251P251delCCT---220.111111
S251P251HcCtcAt22A0.000774
S251P251HcCtcAt22AD.20.000438
S251P251PccTccA22AY.1020.000053
S251P251HcCtcAt12AY.1200.000037
S251P251HcCTcAC12AY.1200.000037
S251P251LcCtcTt22AY.230.000139
S251P251HcCtcAt22AY.260.000057
S251P251SCctTct22AY.290.000032
S251P251PccTccG22AY.360.000296
S251P251LcCtcTt22AY.360.000296
S251P251LcCtcTt22AY.4.2.10.000298
S251P251LcCtcTt22AY.4.30.001684
S251P251delCCT---22AY.4.50.000215
S251P251LcCtcTt22AY.420.00008
S251P251PccTccA12AY.420.00004
S251P251PccTccC12AY.420.00004
S251P251SCctTct22AY.430.000009
S251P251delCCT---22AY.440.000012
S251P251del1ccTcc-12AY.440.000006
S251P251del1Cct-ct12AY.440.000006
S251P251LcCtcTt22AY.450.000243
S251P251LcCtcTt22AY.46.20.001271
S251P251LcCtcTt22AY.46.40.000329
S251P251PccTccC22AY.46.60.000144
S251P251LcCtcTt22AY.50.000041
S251P251RcCtcGt22AY.50.000041
S251P251LcCtcTt22AY.5.30.000675
S251P251HcCtcAt22AY.500.001599
S251P251del1Cct-ct22AY.520.001629
S251P251HcCtcAt22AY.610.00021
S251P251TCctAct22AY.670.000929
S251P251LcCtcTt22AY.80.001212
S251P251SCctTct22AY.880.001768
S251P251LcCtcTt22AY.920.000575
S251P251LcCtcTt22AY.930.000546
S251P251HcCtcAt22AY.980.000158
S251P251LcCtcTt22AY.99.20.000184
S251P251SCctTct22B0.000256
S251P251FCCtTTt22B.10.000018
S251P251RcCtcGt22B.1.10.000036
S251P251delCCT---22B.1.10.000036
S251P251PccTccC22B.1.10.000036
S251P251HcCtcAt22B.1.1.250.001137
S251P251HcCtcAt22B.1.1.280.000622
S251P251SCctTct22B.1.1.280.000622
S251P251PccTccC22B.1.1.330.000842
S251P251LcCtcTt22B.1.1.4320.002532
S251P251LcCtcTt22B.1.1.470.010695
S251P251LcCtcTt22B.1.1390.001466
S251P251LcCtcTt22B.1.1600.000062
S251P251del1Cct-ct22B.1.1600.000062
S251P251SCctTct22B.1.1770.000026
S251P251LcCtcTt22B.1.1770.000026
S251P251LcCtcTt22B.1.177.600.000437
S251P251SCctTct22B.1.177.730.001133
S251P251TCctAct22B.1.177.810.000379
S251P251delCCT---22B.1.20.000018
S251P251FCCtTTt22B.1.20.000018
S251P251SCctTct22B.1.3510.000059
S251P251TCctAct22B.1.3510.000059
S251P251HcCtcAt22B.1.4090.001563
S251P251delCCT---22B.1.5250.000226
S251P251HcCtcAt22B.1.6100.007092
S251P251HcCtcAt22B.1.617.10.000258
S251P251PccTccC22B.1.617.20.000008
S251P251SCctTct22B.1.6340.006849
S251P251RcCTcGA12C.370.000116
S251P251del2CCt--t12C.370.000116
S251P251del2CCT--N12C.370.000116
S251P251RcCtcGt12C.370.000116
S251P251delCCT---22C.390.037736
S251P251HcCtcAt22P.1.120.000968
S251P251LcCtcTt22P.20.000373
S251P251HcCtcAt22R.10.00018
S251P251TCctAct11A0.000387
S251P251SCctTct11A.10.000282
S251P251delCCT---11A.2.50.000499
S251P251SCctTct11A.2.50.000499
S251P251PccTccC11A.2.50.000499
S251P251CCCtTGt11All0
S251P251ACctGct11All0
S251P251NCCtAAt11All0
S251P251HcCtcAt11AY.1000.000046
S251P251delCCT---11AY.1010.00049
S251P251SCctTct11AY.1020.000027
S251P251LcCtcTt11AY.1020.000027
S251P251PccTccG11AY.1030.000006
S251P251LcCtcTt11AY.1050.000643
S251P251LcCtcTt11AY.1060.000335
S251P251HcCtcAt11AY.1080.001103
S251P251delCCT---11AY.1110.000183
S251P251TCctAct11AY.1130.000142
S251P251delCCT---11AY.1170.000085
S251P251HcCtcAt11AY.1170.000085
S251P251LcCtcTt11AY.1170.000085
S251P251TCctAct11AY.1180.000063
S251P251SCctTct11AY.1180.000063
S251P251delCCT---11AY.1180.000063
S251P251HcCtcAt11AY.1190.000035
S251P251LcCtcTt11AY.1210.000135
S251P251RcCtcGt11AY.160.00038
S251P251LcCtcTt11AY.16.10.00047
S251P251LcCtcTt11AY.200.000039
S251P251PccTccC11AY.200.000039
S251P251RcCtcGt11AY.220.002092
S251P251PccTccC11AY.230.00007
S251P251TCctAct11AY.230.00007
S251P251LcCtcTt11AY.240.000431
S251P251HcCtcAt11AY.240.000431
S251P251PccTccA11AY.260.000028
S251P251PccTccA11AY.270.000065
S251P251LcCtcTt11AY.290.000016
S251P251HcCtcAt11AY.290.000016
S251P251delCCT---11AY.30.00001
S251P251PccTccA11AY.30.00001
S251P251delCCT---11AY.330.000067
S251P251SCctTct11AY.330.000067
S251P251HcCtcAt11AY.340.000097
S251P251PccTccC11AY.390.000025
S251P251SCctTct11AY.390.000025
S251P251RcCtcGt11AY.390.000025
S251P251HcCtcAt11AY.4.50.000107
S251P251LcCtcTt11AY.4.50.000107
S251P251del1CCT-NN11AY.430.000004
S251P251TCctAct11AY.440.000006
S251P251ACctGct11AY.440.000006
S251P251PccTccA11AY.450.000122
S251P251SCctTct11AY.450.000122
S251P251HcCtcAt11AY.460.000104
S251P251LcCtcTt11AY.470.000031
S251P251HcCtcAt11AY.510.000909
S251P251LcCtcTt11AY.530.000288
S251P251HcCtcAt11AY.550.000917
S251P251LcCtcTt11AY.590.00053
S251P251HcCtcAt11AY.60.000041
S251P251LcCtcTt11AY.610.000105
S251P251delCCT---11AY.650.000533
S251P251FCCtTTt11AY.670.000464
S251P251LcCtcTt11AY.680.000274
S251P251LcCtcTt11AY.690.000187
S251P251PccTccA11AY.7.10.000113
S251P251LcCtcTt11AY.7.20.000559
S251P251PccTccA11AY.710.000475
S251P251HcCtcAt11AY.710.000475
S251P251LcCtcTt11AY.720.001361
S251P251SCctTct11AY.740.000116
S251P251LcCtcTt11AY.790.001211
S251P251LcCtcTt11AY.820.001357
S251P251LcCtcTt11AY.90.000068
S251P251HcCtcAt11AY.9.10.000084
S251P251SCctTct11AY.9.10.000084
S251P251HcCtcAt11AY.9.20.000037
S251P251delCCT---11AY.9.20.000037
S251P251LcCtcTt11AY.940.000443
S251P251delCCT---11AY.950.000761
S251P251HcCtcAt11B0.000128
S251P251TCctAct11B0.000128
S251P251LcCtcTt11B0.000128
S251P251NCCtAAt11B.10.000009
S251P251TCctAct11B.1.10.000018
S251P251LcCtcTt11B.1.10.000018
S251P251delCCT---11B.1.1.10.000327
S251P251delCCT---11B.1.1.1590.004673
S251P251LcCtcTt11B.1.1.2140.000055
S251P251PccTccG11B.1.1.2140.000055
S251P251HcCtcAt11B.1.1.2200.001859
S251P251PccTccC11B.1.1.2220.000204
S251P251HcCtcAt11B.1.1.2220.000204
S251P251HcCtcAt11B.1.1.2610.008621
S251P251HcCtcAt11B.1.1.2630.001558
S251P251TCctAct11B.1.1.270.00565
S251P251TCctAct11B.1.1.2840.000107
S251P251LcCtcTt11B.1.1.2910.000742
S251P251LcCtcTt11B.1.1.3060.000438
S251P251LcCtcTt11B.1.1.3170.000412
S251P251LcCtcTt11B.1.1.330.000421
S251P251delCCT---11B.1.1.3480.000796
S251P251SCctTct11B.1.1.3480.000796
S251P251SCctTct11B.1.1.3690.000446
S251P251delCCT---11B.1.1.3720.000689
S251P251LcCtcTt11B.1.1.4610.012048
S251P251LcCtcTt11B.1.1.5230.001563
S251P251delCCT---11B.1.1.5280.004808
S251P251RcCtcGt11B.1.1.70.000001
S251P251LcCtcTt11B.1.110.30.000718
S251P251SCctTct11B.1.130.002375
S251P251SCctTct11B.1.177.100.000878
S251P251LcCtcTt11B.1.177.150.000631
S251P251del1Cct-ct11B.1.177.60.000977
S251P251delCCT---11B.1.177.690.001484
S251P251LcCtcTt11B.1.177.70.000165
S251P251delCCT---11B.1.177.760.002494
S251P251TCctAct11B.1.20.000009
S251P251del1Cct-ct11B.1.20.000009
S251P251SCctTct11B.1.2060.000816
S251P251SCctTct11B.1.2340.000132
S251P251SCctTct11B.1.2390.001221
S251P251HcCtcAt11B.1.2410.000812
S251P251PccTccG11B.1.2430.00007
S251P251LcCtcTt11B.1.2580.000067
S251P251SCctTct11B.1.258.170.000104
S251P251SCctTct11B.1.3370.005587
S251P251delCCT---11B.1.3510.00003
S251P251PccTccC11B.1.360.000146
S251P251del1Cct-ct11B.1.36.10.00114
S251P251PccTccC11B.1.3610.001289
S251P251SCctTct11B.1.3960.000706
S251P251PccTccC11B.1.4260.001009
S251P251delCCT---11B.1.4290.000024
S251P251LcCtcTt11B.1.4290.000024
S251P251LcCtcTt11B.1.4320.011236
S251P251SCctTct11B.1.438.10.000107
S251P251SCctTct11B.1.4620.007246
S251P251SCctTct11B.1.5170.000427
S251P251LcCtcTt11B.1.5250.000113
S251P251TCctAct11B.1.5260.000024
S251P251SCctTct11B.1.5610.000397
S251P251delCCT---11B.1.5610.000397
S251P251HcCtcAt11B.1.5680.001111
S251P251SCctTct11B.1.5690.014493
S251P251LcCtcTt11B.1.5770.000687
S251P251SCctTct11B.1.5820.000491
S251P251SCctTct11B.1.5950.000261
S251P251LcCtcTt11B.1.5950.000261
S251P251LcCtcTt11B.1.5960.000087
S251P251PccTccC11B.1.5960.000087
S251P251del1Cct-ct11B.1.5960.000087
S251P251PccTccA11B.1.5990.00365
S251P251HcCtcAt11B.1.6050.005952
S251P251HcCtcAt11B.1.6090.000479
S251P251TCctAct11B.1.617.10.000129
S251P251del1Cct-ct11B.1.617.20.000004
S251P251delCCT---11B.1.6200.000946
S251P251del2cCTc--11B.1.6210.000089
S251P251TCctAct11B.1.6230.000536
S251P251TCctAct11B.1.6370.000073
S251P251TCctAct11B.600.015873
S251P251TCctAct11C.230.005814
S251P251PccTccA11C.370.000116
S251P251CCCtTGt11C.370.000116
S251P251FCCtTTt11C.370.000116
S251P251TCctAct11D.20.000075
S251P251LcCtcTt11P.10.000016
S251P251del1Cct-ct11P.10.000016
S251P251delCCT---11P.1.10.000318
S251P251HcCtcAt11P.1.130.000898
S251P251SCctTct11P.1.150.000232
S251P251HcCtcAt11P.1.150.000232
S251P251PccTccA11P.1.150.000232
S251P251LcCtcTt11P.1.40.000977
S251P251HcCtcAt11P.20.000187
S251P251SCctTct11Q.80.000165
S251P251del1Cct-ct11R.10.00009
S251P251LcCtcTt11V.10.022727

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.