CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 189

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	189	L189F		nonsyn	Ctt	Ttt	11334	11332	0.999824	22127-22129
S	189	L189F		nonsyn	CtT	TtC	11334	2	0.00017646	22127-22129
S	189	L189del		del	CTT	---	214	214	1	22127-22129
S	189	L189L		syn	ctT	ctC	87	48	0.551724	22127-22129
S	189	L189L		syn	ctT	ctG	87	20	0.229885	22127-22129
S	189	L189L		syn	ctT	ctA	87	18	0.206897	22127-22129
S	189	L189L		syn	CtT	TtA	87	1	0.0114943	22127-22129
S	189	L189I		nonsyn	Ctt	Att	74	74	1	22127-22129
S	189	L189P		nonsyn	cTt	cCt	12	12	1	22127-22129
S	189	L189R		nonsyn	cTt	cGt	7	6	0.857143	22127-22129
S	189	L189R		nonsyn	cTT	cGC	7	1	0.142857	22127-22129
S	189	L189S		nonsyn	CTt	TCt	6	6	1	22127-22129
S	189	L189del2		del	cTT	c--	6	4	0.666667	22127-22129
S	189	L189del2		del	CTt	--t	6	1	0.166667	22127-22129
S	189	L189del2		del	CTT	--N	6	1	0.166667	22127-22129
S	189	L189H		nonsyn	cTt	cAt	4	4	1	22127-22129
S	189	L189V		nonsyn	Ctt	Gtt	3	3	1	22127-22129
S	189	L189C		nonsyn	CTt	TGt	3	2	0.666667	22127-22129
S	189	L189del1		del	ctT	ct-	3	1	0.333333	22127-22129
S	189	L189del1		del	cTt	c-t	3	1	0.333333	22127-22129
S	189	L189del1		del	Ctt	-tt	3	1	0.333333	22127-22129
S	189	L189C		nonsyn	CTT	TGC	3	1	0.333333	22127-22129

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	189	L189F	Ctt	Ttt	11332	11334	All	0.002167
S	189	L189F	CtT	TtC	2	11334	All	0
S	189	L189F	Ctt	Ttt	9532	9532	B.1.258.17	0.991058
S	189	L189F	Ctt	Ttt	288	288	B.1.258.4	0.993103
S	189	L189F	Ctt	Ttt	243	243	AY.25	0.001462
S	189	L189del	CTT	---	214	214	All	0.000041
S	189	L189F	Ctt	Ttt	178	178	AY.9	0.012032
S	189	L189F	Ctt	Ttt	151	151	B.1	0.001383
S	189	L189F	Ctt	Ttt	143	143	B.1.258	0.009516
S	189	L189F	Ctt	Ttt	114	114	B.1.258.5	1
S	189	L189F	Ctt	Ttt	93	93	AY.4	0.000145
S	189	L189L	ctT	ctC	48	87	All	0.000009
S	189	L189L	ctT	ctG	20	87	All	0.000004
S	189	L189L	ctT	ctA	18	87	All	0.000003
S	189	L189L	CtT	TtA	1	87	All	0
S	189	L189I	Ctt	Att	74	74	All	0.000014
S	189	L189F	Ctt	Ttt	63	63	B.1.1.432	0.079747
S	189	L189F	Ctt	Ttt	53	53	B.1.1.7	0.000047
S	189	L189del	CTT	---	44	44	B.1.1.7	0.000039
S	189	L189F	Ctt	Ttt	43	43	B.1.2	0.000379
S	189	L189F	Ctt	Ttt	41	41	B.1.258.23	0.97619
S	189	L189F	Ctt	Ttt	31	31	B.1.177	0.000408
S	189	L189F	Ctt	Ttt	31	31	B.1.609	0.014861
S	189	L189del	CTT	---	31	31	P.1	0.000488
S	189	L189F	Ctt	Ttt	29	29	B.1.617.2	0.000109
S	189	L189F	Ctt	Ttt	28	28	P.1	0.000441
S	189	L189F	Ctt	Ttt	25	25	B.1.1	0.000454
S	189	L189F	Ctt	Ttt	22	22	B.1.311	0.006041
S	189	L189F	Ctt	Ttt	19	19	B.1.258.24	0.204301
S	189	L189I	Ctt	Att	16	16	AY.9.1	0.00134
S	189	L189del	CTT	---	14	14	AY.43	0.000062
S	189	L189F	Ctt	Ttt	14	14	AY.44	0.000085
S	189	L189F	Ctt	Ttt	14	14	B.1.367	0.011094
S	189	L189P	cTt	cCt	12	12	All	0.000002
S	189	L189L	ctT	ctA	6	12	B.1.1.7	0.000005
S	189	L189L	ctT	ctC	6	12	B.1.1.7	0.000005
S	189	L189F	Ctt	Ttt	11	11	AY.43	0.000049
S	189	L189del	CTT	---	11	11	B.1.177	0.000145
S	189	L189L	ctT	ctC	8	11	B.1.2	0.00007
S	189	L189L	ctT	ctG	2	11	B.1.2	0.000018
S	189	L189L	ctT	ctA	1	11	B.1.2	0.000009
S	189	L189del	CTT	---	10	10	B.1	0.000092
S	189	L189del	CTT	---	9	9	AY.4	0.000014
S	189	L189del	CTT	---	9	9	P.1.15	0.002091
S	189	L189del	CTT	---	8	8	AY.4.5	0.00086
S	189	L189I	Ctt	Att	8	8	AY.43	0.000035
S	189	L189L	ctT	ctG	7	8	AY.44	0.000043
S	189	L189L	ctT	ctA	1	8	AY.44	0.000006
S	189	L189F	Ctt	Ttt	8	8	B	0.001022
S	189	L189F	Ctt	Ttt	8	8	B.1.1.519	0.000318
S	189	L189R	cTt	cGt	6	7	All	0.000001
S	189	L189R	cTT	cGC	1	7	All	0
S	189	L189L	ctT	ctC	7	7	B.1.1	0.000127
S	189	L189F	Ctt	Ttt	7	7	B.4.1	0.132075
S	189	L189F	Ctt	Ttt	6	6	AE.8	0.002934
S	189	L189S	CTt	TCt	6	6	All	0.000001
S	189	L189del2	cTT	c--	4	6	All	0.000001
S	189	L189del2	CTT	--N	1	6	All	0
S	189	L189del2	CTt	--t	1	6	All	0
S	189	L189I	Ctt	Att	6	6	AY.42	0.000241
S	189	L189I	Ctt	Att	6	6	B.1	0.000055
S	189	L189I	Ctt	Att	6	6	B.1.1	0.000109
S	189	L189F	Ctt	Ttt	6	6	B.1.160	0.000187
S	189	L189del	CTT	---	6	6	B.1.617.2	0.000023
S	189	L189L	ctT	ctC	3	6	B.1.617.2	0.000011
S	189	L189L	ctT	ctG	2	6	B.1.617.2	0.000008
S	189	L189L	ctT	ctA	1	6	B.1.617.2	0.000004
S	189	L189del	CTT	---	6	6	C.37	0.000696
S	189	L189del	CTT	---	6	6	P.1.16	0.002245
S	189	L189L	ctT	ctA	5	5	AZ.1	0.004337
S	189	L189F	Ctt	Ttt	5	5	B.1.221	0.000355
S	189	L189del	CTT	---	5	5	B.1.36	0.00073
S	189	L189F	Ctt	Ttt	5	5	B.1.375	0.004098
S	189	L189H	cTt	cAt	4	4	All	0.000001
S	189	L189F	Ctt	Ttt	4	4	AY.103	0.000025
S	189	L189F	Ctt	Ttt	4	4	AY.42	0.000161
S	189	L189F	Ctt	Ttt	4	4	AY.8	0.002424
S	189	L189F	Ctt	Ttt	4	4	AY.95	0.003044
S	189	L189L	ctT	ctC	4	4	B.1	0.000037
S	189	L189I	Ctt	Att	4	4	B.1.1.7	0.000004
S	189	L189R	cTt	cGt	4	4	B.1.1.7	0.000004
S	189	L189F	Ctt	Ttt	4	4	B.1.177.54	0.002426
S	189	L189F	Ctt	Ttt	4	4	P.1.12	0.001936
S	189	L189L	ctT	ctA	1	3		0.055556
S	189	L189L	CtT	TtA	1	3		0.055556
S	189	L189L	ctT	ctC	1	3		0.055556
S	189	L189V	Ctt	Gtt	3	3	All	0.000001
S	189	L189C	CTt	TGt	2	3	All	0
S	189	L189C	CTT	TGC	1	3	All	0
S	189	L189del1	Ctt	-tt	1	3	All	0
S	189	L189del1	cTt	c-t	1	3	All	0
S	189	L189del1	ctT	ct-	1	3	All	0
S	189	L189F	Ctt	Ttt	3	3	AY.13	0.000483
S	189	L189del	CTT	---	3	3	AY.25	0.000018
S	189	L189F	Ctt	Ttt	3	3	AY.41	0.000882
S	189	L189F	Ctt	Ttt	3	3	AY.98.1	0.000145
S	189	L189L	ctT	ctG	3	3	B.1.1.464	0.004418
S	189	L189P	cTt	cCt	3	3	B.1.1.7	0.000003
S	189	L189F	Ctt	Ttt	3	3	B.1.36.38	0.004926
S	189	L189F	Ctt	Ttt	3	3	B.1.497	0.000944
S	189	L189I	Ctt	Att	3	3	B.1.617.2	0.000011
S	189	L189F	Ctt	Ttt	3	3	P.1.1	0.000953
S	189	L189I	Ctt	Att	3	3	P.1.14	0.000143
S	189	L189S	CTt	TCt	2	2		0.111111
S	189	L189F	Ctt	Ttt	1	2		0.055556
S	189	L189F	CtT	TtC	1	2		0.055556
S	189	L189del	CTT	---	2	2	AY.120	0.000074
S	189	L189I	Ctt	Att	2	2	AY.23	0.000139
S	189	L189del	CTT	---	2	2	AY.29	0.000032
S	189	L189F	Ctt	Ttt	2	2	AY.33	0.000134
S	189	L189I	Ctt	Att	2	2	AY.33	0.000134
S	189	L189F	Ctt	Ttt	2	2	AY.39	0.000049
S	189	L189I	Ctt	Att	2	2	AY.4	0.000003
S	189	L189L	ctT	ctC	1	2	AY.4	0.000002
S	189	L189L	ctT	ctG	1	2	AY.4	0.000002
S	189	L189L	ctT	ctG	1	2	AY.4.2	0.000022
S	189	L189L	ctT	ctC	1	2	AY.4.2	0.000022
S	189	L189del	CTT	---	2	2	AY.44	0.000012
S	189	L189del	CTT	---	2	2	AY.46.2	0.001271
S	189	L189F	Ctt	Ttt	2	2	AY.5.3	0.000675
S	189	L189F	Ctt	Ttt	2	2	AY.7	0.000392
S	189	L189del	CTT	---	2	2	AY.9	0.000135
S	189	L189C	CTt	TGt	1	2	AY.98	0.000079
S	189	L189C	CTT	TGC	1	2	AY.98	0.000079
S	189	L189F	CtT	TtC	1	2	AY.98	0.000079
S	189	L189F	Ctt	Ttt	1	2	AY.98	0.000079
S	189	L189R	cTT	cGC	1	2	AY.98	0.000079
S	189	L189R	cTt	cGt	1	2	AY.98	0.000079
S	189	L189P	cTt	cCt	2	2	B.1	0.000018
S	189	L189del	CTT	---	2	2	B.1.1	0.000036
S	189	L189F	Ctt	Ttt	2	2	B.1.1.220	0.003717
S	189	L189F	Ctt	Ttt	2	2	B.1.1.222	0.000408
S	189	L189F	Ctt	Ttt	2	2	B.1.1.409	0.005666
S	189	L189del2	CTt	--t	1	2	B.1.1.7	0.000001
S	189	L189del2	cTT	c--	1	2	B.1.1.7	0.000001
S	189	L189del	CTT	---	2	2	B.1.177.16	0.001329
S	189	L189F	Ctt	Ttt	2	2	B.1.177.73	0.001133
S	189	L189del	CTT	---	2	2	B.1.2	0.000018
S	189	L189F	Ctt	Ttt	2	2	B.1.36	0.000292
S	189	L189F	Ctt	Ttt	2	2	B.1.36.8	0.002
S	189	L189F	Ctt	Ttt	2	2	B.1.429	0.000047
S	189	L189del	CTT	---	2	2	B.1.621	0.000177
S	189	L189F	Ctt	Ttt	2	2	C.37	0.000232
S	189	L189I	Ctt	Att	2	2	P.1	0.000032
S	189	L189F	Ctt	Ttt	2	2	P.1.2	0.002312
S	189	L189I	Ctt	Att	1	1	A	0.000387
S	189	L189F	Ctt	Ttt	1	1	A.2.5	0.000499
S	189	L189del	CTT	---	1	1	A.2.5	0.000499
S	189	L189L	ctT	ctA	1	1	AY.10	0.00053
S	189	L189L	ctT	ctC	1	1	AY.100	0.000046
S	189	L189del	CTT	---	1	1	AY.100	0.000046
S	189	L189S	CTt	TCt	1	1	AY.103	0.000006
S	189	L189I	Ctt	Att	1	1	AY.103	0.000006
S	189	L189L	ctT	ctC	1	1	AY.113	0.000142
S	189	L189F	Ctt	Ttt	1	1	AY.116	0.000287
S	189	L189I	Ctt	Att	1	1	AY.121	0.000135
S	189	L189H	cTt	cAt	1	1	AY.14	0.000088
S	189	L189F	Ctt	Ttt	1	1	AY.23	0.00007
S	189	L189del	CTT	---	1	1	AY.24	0.000431
S	189	L189del2	CTT	--N	1	1	AY.25	0.000006
S	189	L189P	cTt	cCt	1	1	AY.25	0.000006
S	189	L189del	CTT	---	1	1	AY.26	0.000028
S	189	L189del	CTT	---	1	1	AY.3	0.00001
S	189	L189del1	Ctt	-tt	1	1	AY.33	0.000067
S	189	L189L	ctT	ctA	1	1	AY.33	0.000067
S	189	L189P	cTt	cCt	1	1	AY.39	0.000025
S	189	L189del2	cTT	c--	1	1	AY.4	0.000002
S	189	L189F	Ctt	Ttt	1	1	AY.4.2	0.000022
S	189	L189F	Ctt	Ttt	1	1	AY.4.5	0.000107
S	189	L189L	ctT	ctG	1	1	AY.42	0.00004
S	189	L189C	CTt	TGt	1	1	AY.44	0.000006
S	189	L189P	cTt	cCt	1	1	AY.45	0.000122
S	189	L189I	Ctt	Att	1	1	AY.46	0.000104
S	189	L189F	Ctt	Ttt	1	1	AY.46.4	0.000165
S	189	L189I	Ctt	Att	1	1	AY.46.6	0.000072
S	189	L189L	ctT	ctC	1	1	AY.46.6	0.000072
S	189	L189del	CTT	---	1	1	AY.47	0.000031
S	189	L189I	Ctt	Att	1	1	AY.5	0.000021
S	189	L189F	Ctt	Ttt	1	1	AY.5	0.000021
S	189	L189F	Ctt	Ttt	1	1	AY.52	0.000814
S	189	L189F	Ctt	Ttt	1	1	AY.54	0.000095
S	189	L189I	Ctt	Att	1	1	AY.60	0.000938
S	189	L189L	ctT	ctC	1	1	AY.75	0.000056
S	189	L189F	Ctt	Ttt	1	1	AY.75	0.000056
S	189	L189I	Ctt	Att	1	1	AY.75	0.000056
S	189	L189P	cTt	cCt	1	1	AY.75.1	0.00018
S	189	L189F	Ctt	Ttt	1	1	AY.75.1	0.00018
S	189	L189L	ctT	ctG	1	1	AY.85	0.000427
S	189	L189P	cTt	cCt	1	1	AY.85	0.000427
S	189	L189R	cTt	cGt	1	1	AY.9	0.000068
S	189	L189F	Ctt	Ttt	1	1	AY.9.2	0.000037
S	189	L189del	CTT	---	1	1	AY.96	0.002075
S	189	L189L	ctT	ctC	1	1	AY.98	0.000079
S	189	L189I	Ctt	Att	1	1	AY.98.1	0.000048
S	189	L189L	ctT	ctC	1	1	B	0.000128
S	189	L189del	CTT	---	1	1	B	0.000128
S	189	L189I	Ctt	Att	1	1	B	0.000128
S	189	L189S	CTt	TCt	1	1	B.1	0.000009
S	189	L189H	cTt	cAt	1	1	B.1	0.000009
S	189	L189V	Ctt	Gtt	1	1	B.1	0.000009
S	189	L189del1	ctT	ct-	1	1	B.1.1.170	0.001247
S	189	L189F	Ctt	Ttt	1	1	B.1.1.198	0.001468
S	189	L189F	Ctt	Ttt	1	1	B.1.1.263	0.001558
S	189	L189L	ctT	ctC	1	1	B.1.1.28	0.000311
S	189	L189F	Ctt	Ttt	1	1	B.1.1.284	0.000107
S	189	L189del	CTT	---	1	1	B.1.1.311	0.000358
S	189	L189del	CTT	---	1	1	B.1.1.315	0.008475
S	189	L189L	ctT	ctC	1	1	B.1.1.316	0.000925
S	189	L189F	Ctt	Ttt	1	1	B.1.1.317	0.000412
S	189	L189F	Ctt	Ttt	1	1	B.1.1.318	0.000302
S	189	L189L	ctT	ctC	1	1	B.1.1.33	0.000421
S	189	L189F	Ctt	Ttt	1	1	B.1.1.348	0.000796
S	189	L189F	Ctt	Ttt	1	1	B.1.1.445	0.037037
S	189	L189P	cTt	cCt	1	1	B.1.1.519	0.00004
S	189	L189V	Ctt	Gtt	1	1	B.1.1.7	0.000001
S	189	L189del1	cTt	c-t	1	1	B.1.1.7	0.000001
S	189	L189S	CTt	TCt	1	1	B.1.1.7	0.000001
S	189	L189del	CTT	---	1	1	B.1.1.70	0.000341
S	189	L189F	Ctt	Ttt	1	1	B.1.1.70	0.000341
S	189	L189F	Ctt	Ttt	1	1	B.1.139	0.000733
S	189	L189del	CTT	---	1	1	B.1.140	0.018868
S	189	L189F	Ctt	Ttt	1	1	B.1.157	0.002985
S	189	L189del	CTT	---	1	1	B.1.160	0.000031
S	189	L189L	ctT	ctC	1	1	B.1.160.22	0.006757
S	189	L189del	CTT	---	1	1	B.1.160.23	0.004831
S	189	L189del2	cTT	c--	1	1	B.1.177	0.000013
S	189	L189L	ctT	ctC	1	1	B.1.177	0.000013
S	189	L189del2	cTT	c--	1	1	B.1.177.10	0.000878
S	189	L189F	Ctt	Ttt	1	1	B.1.177.12	0.000152
S	189	L189del	CTT	---	1	1	B.1.177.18	0.00116
S	189	L189del	CTT	---	1	1	B.1.177.21	0.000076
S	189	L189F	Ctt	Ttt	1	1	B.1.177.33	0.001645
S	189	L189F	Ctt	Ttt	1	1	B.1.177.4	0.000211
S	189	L189F	Ctt	Ttt	1	1	B.1.177.52	0.001757
S	189	L189del	CTT	---	1	1	B.1.177.6	0.000977
S	189	L189del	CTT	---	1	1	B.1.177.62	0.001192
S	189	L189del	CTT	---	1	1	B.1.177.69	0.001484
S	189	L189F	Ctt	Ttt	1	1	B.1.177.7	0.000165
S	189	L189del	CTT	---	1	1	B.1.218	0.005155
S	189	L189I	Ctt	Att	1	1	B.1.221	0.000071
S	189	L189F	Ctt	Ttt	1	1	B.1.23	0.006061
S	189	L189F	Ctt	Ttt	1	1	B.1.232	0.000537
S	189	L189F	Ctt	Ttt	1	1	B.1.237	0.004975
S	189	L189F	Ctt	Ttt	1	1	B.1.243	0.00007
S	189	L189del	CTT	---	1	1	B.1.258	0.000067
S	189	L189del	CTT	---	1	1	B.1.258.3	0.001675
S	189	L189I	Ctt	Att	1	1	B.1.301	0.005917
S	189	L189F	Ctt	Ttt	1	1	B.1.328	0.03125
S	189	L189F	Ctt	Ttt	1	1	B.1.356	0.001727
S	189	L189del	CTT	---	1	1	B.1.36.18	0.00042
S	189	L189del	CTT	---	1	1	B.1.36.2	0.010753
S	189	L189F	Ctt	Ttt	1	1	B.1.36.26	0.002857
S	189	L189L	ctT	ctC	1	1	B.1.36.8	0.001
S	189	L189F	Ctt	Ttt	1	1	B.1.362	0.001541
S	189	L189L	ctT	ctC	1	1	B.1.369	0.000285
S	189	L189S	CTt	TCt	1	1	B.1.391	0.001127
S	189	L189F	Ctt	Ttt	1	1	B.1.391	0.001127
S	189	L189P	cTt	cCt	1	1	B.1.391	0.001127
S	189	L189del	CTT	---	1	1	B.1.409	0.000781
S	189	L189L	ctT	ctA	1	1	B.1.427	0.00005
S	189	L189L	ctT	ctG	1	1	B.1.429	0.000024
S	189	L189del	CTT	---	1	1	B.1.438.1	0.000107
S	189	L189F	Ctt	Ttt	1	1	B.1.470	0.001404
S	189	L189H	cTt	cAt	1	1	B.1.497	0.000315
S	189	L189F	Ctt	Ttt	1	1	B.1.524	0.001406
S	189	L189F	Ctt	Ttt	1	1	B.1.526	0.000024
S	189	L189del	CTT	---	1	1	B.1.561	0.000397
S	189	L189F	Ctt	Ttt	1	1	B.1.575	0.000303
S	189	L189F	Ctt	Ttt	1	1	B.1.590	0.004545
S	189	L189L	ctT	ctC	1	1	B.1.596	0.000087
S	189	L189F	Ctt	Ttt	1	1	B.1.599	0.00365
S	189	L189del	CTT	---	1	1	B.1.617.1	0.000129
S	189	L189H	cTt	cAt	1	1	B.1.617.2	0.000004
S	189	L189F	Ctt	Ttt	1	1	B.1.619	0.000871
S	189	L189del	CTT	---	1	1	B.1.620	0.000946
S	189	L189del	CTT	---	1	1	B.1.621.1	0.000506
S	189	L189I	Ctt	Att	1	1	B.1.623	0.000536
S	189	L189F	Ctt	Ttt	1	1	B.1.623	0.000536
S	189	L189F	Ctt	Ttt	1	1	B.1.627	0.00202
S	189	L189L	ctT	ctG	1	1	B.1.630	0.005236
S	189	L189del	CTT	---	1	1	B.1.638	0.052632
S	189	L189L	ctT	ctC	1	1	B.31	0.003731
S	189	L189del	CTT	---	1	1	B.34	0.013699
S	189	L189I	Ctt	Att	1	1	B.6	0.00091
S	189	L189F	Ctt	Ttt	1	1	C.13	0.025641
S	189	L189L	ctT	ctC	1	1	C.35	0.000774
S	189	L189F	Ctt	Ttt	1	1	D.2	0.000075
S	189	L189V	Ctt	Gtt	1	1	P.1	0.000016
S	189	L189del	CTT	---	1	1	P.1.1	0.000318
S	189	L189F	Ctt	Ttt	1	1	P.1.14	0.000048
S	189	L189F	Ctt	Ttt	1	1	P.1.15	0.000232
S	189	L189F	Ctt	Ttt	1	1	P.1.16	0.000374
S	189	L189F	Ctt	Ttt	1	1	P.1.17	0.000162
S	189	L189L	ctT	ctC	1	1	Q.8	0.000165
S	189	L189del	CTT	---	1	1	U.3	0.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.