CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 157 & Codon = tCc

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	157	F157S		nonsyn	tTc	tCc	15537	15239	0.98082	22031-22033

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	157	F157S	tTc	tCc	15239	15537	All	0.002915
S	157	F157S	tTc	tCc	13499	13506	B.1.637	0.986408
S	157	F157S	tTc	tCc	652	653	B.1	0.005972
S	157	F157S	tTc	tCc	389	393	B.1.1	0.007057
S	157	F157S	tTc	tCc	130	130	B.1.632	0.872483
S	157	F157S	tTc	tCc	117	119	B.1.1.7	0.000105
S	157	F157S	tTc	tCc	61	61	B.1.1.192	0.140878
S	157	F157S	tTc	tCc	57	57	B.1.2	0.000502
S	157	F157S	tTc	tCc	31	31	B.1.36	0.004523
S	157	F157S	tTc	tCc	26	26	B.1.526	0.000611
S	157	F157S	tTc	tCc	2	24	AY.43	0.000009
S	157	F157S	tTc	tCc	22	22	B.1.1.419	0.162963
S	157	F157S	tTc	tCc	4	22	B.1.617.2	0.000015
S	157	F157S	tTc	tCc	19	19	B.1.177.7	0.003132
S	157	F157S	tTc	tCc	1	16	AY.25	0.000006
S	157	F157S	tTc	tCc	15	15	A.2.5	0.007485
S	157	F157S	tTc	tCc	8	15	AY.44	0.000049
S	157	F157S	tTc	tCc	15	15	P.1	0.000236
S	157	F157S	tTc	tCc	1	13	AY.26	0.000028
S	157	F157S	tTc	tCc	12	12	B	0.001534
S	157	F157S	tTc	tCc	9	9	B.1.1.507	0.078261
S	157	F157S	tTc	tCc	1	7	AY.9.2	0.000037
S	157	F157S	tTc	tCc	7	7	B.1.1.189	0.01059
S	157	F157S	tTc	tCc	7	7	B.1.214.2	0.004197
S	157	F157S	tTc	tCc	7	7	B.1.596	0.00061
S	157	F157S	tTc	tCc	7	7	B.1.636	0.04698
S	157	F157S	tTc	tCc	6	6	B.1.466.2	0.002347
S	157	F157S	tTc	tCc	6	6	B.1.551	0.007742
S	157	F157S	tTc	tCc	3	5	AY.103	0.000019
S	157	F157S	tTc	tCc	5	5	B.1.160	0.000156
S	157	F157S	tTc	tCc	5	5	B.1.177.73	0.002831
S	157	F157S	tTc	tCc	5	5	B.1.621	0.000443
S	157	F157S	tTc	tCc	2	4	AY.3	0.00002
S	157	F157S	tTc	tCc	4	4	B.1.3	0.010471
S	157	F157S	tTc	tCc	4	4	B.1.623	0.002146
S	157	F157S	tTc	tCc	3	3	B.1.177	0.00004
S	157	F157S	tTc	tCc	3	3	B.1.427	0.000151
S	157	F157S	tTc	tCc	3	3	B.1.609	0.001438
S	157	F157S	tTc	tCc	3	3	B.1.618	0.012097
S	157	F157S	tTc	tCc	3	3	C.37	0.000348
S	157	F157S	tTc	tCc	3	3	D.2	0.000225
S	157	F157S	tTc	tCc	3	3	N.5	0.0053
S	157	F157S	tTc	tCc	3	3	P.1.1	0.000953
S	157	F157S	tTc	tCc	3	3	P.1.17	0.000485
S	157	F157S	tTc	tCc	2	2	A.2.5.2	0.003145
S	157	F157S	tTc	tCc	2	2	B.1.1.214	0.000111
S	157	F157S	tTc	tCc	2	2	B.1.1.220	0.003717
S	157	F157S	tTc	tCc	2	2	B.1.1.372	0.001377
S	157	F157S	tTc	tCc	2	2	B.1.1.397	0.004505
S	157	F157S	tTc	tCc	2	2	B.1.1.448	0.004065
S	157	F157S	tTc	tCc	2	2	B.1.1.519	0.000079
S	157	F157S	tTc	tCc	2	2	B.1.234	0.000264
S	157	F157S	tTc	tCc	2	2	B.1.243.1	0.044444
S	157	F157S	tTc	tCc	2	2	B.1.336	0.004878
S	157	F157S	tTc	tCc	2	2	B.1.413	0.008511
S	157	F157S	tTc	tCc	2	2	B.4	0.004415
S	157	F157S	tTc	tCc	1	1	A.5	0.001923
S	157	F157S	tTc	tCc	1	1	AY.100	0.000046
S	157	F157S	tTc	tCc	1	1	AY.120.1	0.000321
S	157	F157S	tTc	tCc	1	1	AY.14	0.000088
S	157	F157S	tTc	tCc	1	1	AY.2	0.000356
S	157	F157S	tTc	tCc	1	1	AY.39	0.000025
S	157	F157S	tTc	tCc	1	1	AY.77	0.001127
S	157	F157S	tTc	tCc	1	1	AY.95	0.000761
S	157	F157S	tTc	tCc	1	1	B.1.1.141	0.002012
S	157	F157S	tTc	tCc	1	1	B.1.1.144	0.028571
S	157	F157S	tTc	tCc	1	1	B.1.1.149	0.016393
S	157	F157S	tTc	tCc	1	1	B.1.1.301	0.001179
S	157	F157S	tTc	tCc	1	1	B.1.1.306	0.000438
S	157	F157S	tTc	tCc	1	1	B.1.1.316	0.000925
S	157	F157S	tTc	tCc	1	1	B.1.1.317	0.000412
S	157	F157S	tTc	tCc	1	1	B.1.1.318	0.000302
S	157	F157S	tTc	tCc	1	1	B.1.1.37	0.000193
S	157	F157S	tTc	tCc	1	1	B.1.1.524	0.020833
S	157	F157S	tTc	tCc	1	1	B.1.1.525	0.005464
S	157	F157S	tTc	tCc	1	1	B.1.1.86	0.035714
S	157	F157S	tTc	tCc	1	1	B.1.127	0.002198
S	157	F157S	tTc	tCc	1	1	B.1.177.54	0.000606
S	157	F157S	tTc	tCc	1	1	B.1.214	0.003663
S	157	F157S	tTc	tCc	1	1	B.1.258	0.000067
S	157	F157S	tTc	tCc	1	1	B.1.280	0.007143
S	157	F157S	tTc	tCc	1	1	B.1.324	0.001605
S	157	F157S	tTc	tCc	1	1	B.1.338	0.008621
S	157	F157S	tTc	tCc	1	1	B.1.350	0.002933
S	157	F157S	tTc	tCc	1	1	B.1.356	0.001727
S	157	F157S	tTc	tCc	1	1	B.1.36.29	0.000517
S	157	F157S	tTc	tCc	1	1	B.1.367	0.000792
S	157	F157S	tTc	tCc	1	1	B.1.375	0.00082
S	157	F157S	tTc	tCc	1	1	B.1.411	0.003704
S	157	F157S	tTc	tCc	1	1	B.1.505	0.004386
S	157	F157S	tTc	tCc	1	1	B.1.509	0.000866
S	157	F157S	tTc	tCc	1	1	B.1.517	0.000427
S	157	F157S	tTc	tCc	1	1	B.1.525	0.000113
S	157	F157S	tTc	tCc	1	1	B.1.533	0.009615
S	157	F157S	tTc	tCc	1	1	B.1.561	0.000397
S	157	F157S	tTc	tCc	1	1	B.1.575	0.000303
S	157	F157S	tTc	tCc	1	1	B.1.576	0.000907
S	157	F157S	tTc	tCc	1	1	B.1.621.1	0.000506
S	157	F157S	tTc	tCc	1	1	B.1.627	0.00202
S	157	F157S	tTc	tCc	1	1	B.1.628	0.000352
S	157	F157S	tTc	tCc	1	1	B.1.630	0.005236
S	157	F157S	tTc	tCc	1	1	B.27	0.015385
S	157	F157S	tTc	tCc	1	1	B.29	0.003509
S	157	F157S	tTc	tCc	1	1	B.6	0.00091
S	157	F157S	tTc	tCc	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.