CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 148 | N148N | syn | aaC | aaT | 3397 | 3397 | 1 | 22004-22006 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 148 | N148N | aaC | aaT | 3397 | 3397 | All | 0.00065 |
S | 148 | N148N | aaC | aaT | 1086 | 1086 | P.1.1 | 0.344981 |
S | 148 | N148N | aaC | aaT | 347 | 347 | B.1.1.7 | 0.000311 |
S | 148 | N148N | aaC | aaT | 286 | 286 | AY.10 | 0.151563 |
S | 148 | N148N | aaC | aaT | 253 | 253 | B.1.1.39 | 0.12895 |
S | 148 | N148N | aaC | aaT | 184 | 184 | B.1.36.1 | 0.209806 |
S | 148 | N148N | aaC | aaT | 172 | 172 | AY.5 | 0.003552 |
S | 148 | N148N | aaC | aaT | 84 | 84 | AY.43 | 0.000372 |
S | 148 | N148N | aaC | aaT | 70 | 70 | B.1.2 | 0.000616 |
S | 148 | N148N | aaC | aaT | 66 | 66 | AY.4 | 0.000103 |
S | 148 | N148N | aaC | aaT | 58 | 58 | P.1.13 | 0.052111 |
S | 148 | N148N | aaC | aaT | 54 | 54 | P.1 | 0.000851 |
S | 148 | N148N | aaC | aaT | 47 | 47 | B.1.617.2 | 0.000177 |
S | 148 | N148N | aaC | aaT | 45 | 45 | AY.44 | 0.000274 |
S | 148 | N148N | aaC | aaT | 39 | 39 | B.1 | 0.000357 |
S | 148 | N148N | aaC | aaT | 38 | 38 | B.1.1 | 0.000689 |
S | 148 | N148N | aaC | aaT | 31 | 31 | AY.25 | 0.000186 |
S | 148 | N148N | aaC | aaT | 26 | 26 | B.1.311 | 0.007139 |
S | 148 | N148N | aaC | aaT | 22 | 22 | AY.103 | 0.000137 |
S | 148 | N148N | aaC | aaT | 21 | 21 | AY.39 | 0.000519 |
S | 148 | N148N | aaC | aaT | 19 | 19 | B.1.427 | 0.000959 |
S | 148 | N148N | aaC | aaT | 18 | 18 | AY.74 | 0.002082 |
S | 148 | N148N | aaC | aaT | 18 | 18 | B.1.466.2 | 0.007042 |
S | 148 | N148N | aaC | aaT | 15 | 15 | B.1.160 | 0.000468 |
S | 148 | N148N | aaC | aaT | 15 | 15 | B.1.177.35 | 0.010366 |
S | 148 | N148N | aaC | aaT | 15 | 15 | Q.3 | 0.002175 |
S | 148 | N148N | aaC | aaT | 14 | 14 | AY.9.2 | 0.000514 |
S | 148 | N148N | aaC | aaT | 14 | 14 | B.1.429 | 0.000329 |
S | 148 | N148N | aaC | aaT | 14 | 14 | B.1.596 | 0.00122 |
S | 148 | N148N | aaC | aaT | 13 | 13 | B.1.177 | 0.000171 |
S | 148 | N148N | aaC | aaT | 13 | 13 | B.1.526 | 0.000306 |
S | 148 | N148N | aaC | aaT | 12 | 12 | AY.102 | 0.000318 |
S | 148 | N148N | aaC | aaT | 11 | 11 | B.1.561 | 0.004367 |
S | 148 | N148N | aaC | aaT | 10 | 10 | A.19 | 0.09434 |
S | 148 | N148N | aaC | aaT | 10 | 10 | B.1.351 | 0.000297 |
S | 148 | N148N | aaC | aaT | 10 | 10 | D.2 | 0.00075 |
S | 148 | N148N | aaC | aaT | 8 | 8 | AY.3 | 0.00008 |
S | 148 | N148N | aaC | aaT | 8 | 8 | B.1.1.161 | 0.028269 |
S | 148 | N148N | aaC | aaT | 8 | 8 | B.1.369 | 0.002282 |
S | 148 | N148N | aaC | aaT | 8 | 8 | B.1.403 | 0.026144 |
S | 148 | N148N | aaC | aaT | 7 | 7 | AY.119 | 0.000247 |
S | 148 | N148N | aaC | aaT | 7 | 7 | B.1.1.365 | 0.039106 |
S | 148 | N148N | aaC | aaT | 7 | 7 | B.1.1.434 | 0.00244 |
S | 148 | N148N | aaC | aaT | 7 | 7 | B.1.438.1 | 0.000751 |
S | 148 | N148N | aaC | aaT | 6 | 6 | AY.47 | 0.000187 |
S | 148 | N148N | aaC | aaT | 6 | 6 | AY.98.1 | 0.000291 |
S | 148 | N148N | aaC | aaT | 6 | 6 | B.1.177.42 | 0.005367 |
S | 148 | N148N | aaC | aaT | 6 | 6 | B.1.525 | 0.000679 |
S | 148 | N148N | aaC | aaT | 5 | 5 | B.1.470 | 0.007022 |
S | 148 | N148N | aaC | aaT | 5 | 5 | P.1.14 | 0.000239 |
S | 148 | N148N | aaC | aaT | 4 | 4 | AY.4.2 | 0.000087 |
S | 148 | N148N | aaC | aaT | 4 | 4 | B.1.1.306 | 0.001754 |
S | 148 | N148N | aaC | aaT | 4 | 4 | B.1.1.348 | 0.003185 |
S | 148 | N148N | aaC | aaT | 4 | 4 | B.1.1.519 | 0.000159 |
S | 148 | N148N | aaC | aaT | 4 | 4 | B.1.177.81 | 0.000757 |
S | 148 | N148N | aaC | aaT | 3 | 3 | AY.29 | 0.000047 |
S | 148 | N148N | aaC | aaT | 3 | 3 | AY.56 | 0.004815 |
S | 148 | N148N | aaC | aaT | 3 | 3 | AY.59 | 0.001589 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.1.216 | 0.002671 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.1.222 | 0.000612 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.1.37 | 0.000579 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.258 | 0.0002 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.258.17 | 0.000312 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.400 | 0.001287 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.621 | 0.000266 |
S | 148 | N148N | aaC | aaT | 3 | 3 | B.1.637 | 0.000219 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AA.7 | 0.018349 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.20 | 0.000078 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.27 | 0.000129 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.3.1 | 0.000171 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.42 | 0.00008 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.46.4 | 0.000329 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.5.3 | 0.000675 |
S | 148 | N148N | aaC | aaT | 2 | 2 | AY.61 | 0.00021 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B | 0.000256 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.1.326 | 0.003521 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.1.420 | 0.002012 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.1.63 | 0.000772 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.177.15 | 0.001262 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.177.45 | 0.000762 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.177.52 | 0.003515 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.178 | 0.047619 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.210 | 0.004264 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.243 | 0.000139 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.258.7 | 0.003824 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.36 | 0.000292 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.409 | 0.001563 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.609 | 0.000959 |
S | 148 | N148N | aaC | aaT | 2 | 2 | B.1.617.1 | 0.000258 |
S | 148 | N148N | aaC | aaT | 2 | 2 | C.37 | 0.000232 |
S | 148 | N148N | aaC | aaT | 2 | 2 | C.38 | 0.016129 |
S | 148 | N148N | aaC | aaT | 2 | 2 | P.2 | 0.000373 |
S | 148 | N148N | aaC | aaT | 2 | 2 | Q.8 | 0.00033 |
S | 148 | N148N | aaC | aaT | 1 | 1 | A | 0.000387 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.114 | 0.000231 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.23 | 0.00007 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.33 | 0.000067 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.34.1 | 0.00051 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.38 | 0.000499 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.46.1 | 0.001027 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.54 | 0.000095 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.58 | 0.000907 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.63 | 0.000387 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.9.1 | 0.000084 |
S | 148 | N148N | aaC | aaT | 1 | 1 | AY.92 | 0.000287 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.1.191 | 0.004762 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.1.214 | 0.000055 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.1.28 | 0.000311 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.1.413 | 0.006897 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.1.521 | 0.005348 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.110.3 | 0.000718 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.126 | 0.001276 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.139 | 0.000733 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.160.26 | 0.002421 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.160.32 | 0.004292 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.177.60 | 0.000218 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.177.7 | 0.000165 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.214 | 0.003663 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.221 | 0.000071 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.234 | 0.000132 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.236 | 0.002053 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.36.36 | 0.000602 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.367 | 0.000792 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.380 | 0.006623 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.411 | 0.003704 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.416 | 0.001269 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.459 | 0.004082 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.499 | 0.00105 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.532 | 0.006211 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.551 | 0.00129 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.576 | 0.000907 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.599 | 0.00365 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.1.621.1 | 0.000506 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.6 | 0.00091 |
S | 148 | N148N | aaC | aaT | 1 | 1 | B.6.1 | 0.026316 |
S | 148 | N148N | aaC | aaT | 1 | 1 | C.16 | 0.00106 |
S | 148 | N148N | aaC | aaT | 1 | 1 | C.26 | 0.007353 |
S | 148 | N148N | aaC | aaT | 1 | 1 | P.1.12 | 0.000484 |
S | 148 | N148N | aaC | aaT | 1 | 1 | P.1.2 | 0.001156 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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